10 Best acne serums of 2025

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Best Choice

1

La Roche-Posay
La Roche-Posay Effaclar Salicylic Acid Treatment to Minimize Pores, Clear Acne Blemishes and Post Acne Marks

25% Off
Main highlights

Pore Minimizing Salicylic Acid Formula
Effaclar's salicylic acid fights acne, minimizes pores, and smoothens skin.

Perfect for Humid Climates and Active Lifestyles
Ideal for those in humid environments or with active routines.

Praised for Immediate Acne Clearing
Customers love its fast action in reducing breakouts.
9.7

Exceptional

Our Rating

8.9
Light weight

8.2
Sheerness

8.0
worth the money
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Value for Money

2

CeraVe
CeraVe Resurfacing Retinol Serum For Post Acne Marks, Formulated With Licorice Root Extract & Niacinamide, Brightening Serum & Pore Minimizer For Face, Post Acne Skin Barrier Repair, Non-Comedogenic

25% Off
Main highlights

Smoother and Even-Toned Skin
Encapsulated retinol for smoother, more even skin tone.

Ideal for Sensitive Skin
Gentle formula suitable for sensitive, dry, and acne-prone skin.

User-Praised Texture Improvement
Notable improvement in skin texture and pore appearance.
9.6

Exceptional

Our Rating

8.9
Fashion

8.9
Aroma

8.7
worth the money
3

The Ordinary
The Ordinary Salicylic Acid 2% Solution, Acne-Fighting Serum for Blemish-Prone Skin, 1 Fl Oz

15% Off
Main highlights

Blemish-Reduction Formula
The Ordinary Salicylic Acid 2% Solution targets acne and blemishes effectively.

Ideal for Oily Skin
Best used for oily and blemish-prone skin types.

Customer Praised Clarity
Users frequently commend its ability to clear skin blemishes.
9.3

Excellent

Our Rating
4

Good Molecules
Good Molecules Niacinamide Serum - 10% Niacinamide Balancing B3 Facial Serum for Acne, Tone, Texture - Brightening and Hydrating Skincare for Face
Main highlights

Bright Healthy Complexion
Refines tone, improves texture, and nourishes skin with Niacinamide.

Ideal for Acne Prone Skin
Best for acne, uneven tone, enlarged pores, and dull texture.

Praised for Affordable Quality
Affordable, smooths skin, easy to use, and fragrance-free.
9.2

Excellent

Our Rating
5

The Ordinary
The Ordinary Niacinamide 10% + Zinc 1%, Smoothing Serum for Blemish-Prone Skin, 1 Fl Oz
Main highlights

Potent Skin Smoothing Formula
The Ordinary Niacinamide 10% + Zinc 1% reduces blemishes and balances sebum production for clearer skin.

Ideal for Blemish-Prone Skin
Perfect for those with oily or acne-prone skin seeking a smoother complexion.

Highly Praised for Reducing Redness
Customers consistently commend its effectiveness in calming and reducing skin redness.
9.1

Excellent

Our Rating
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6

BYOMA
BYOMA Clarifying Serum - Barrier Repair Serum - Clarifying Facial Serum for Acne Prone Skin - Calming Face Serum with Ceramides, Blue Tansy, PHA & Zinc - Balanced & Healthy Skin - 1.01 fl. oz

25% Off
Main highlights

Barrier Boosting Benefits
Features Tri-Ceramide Complex with ceramides, cholesterol, and fatty acids to strengthen skin barrier.

Ideal for Acne Prone Skin
Perfect for calming, clearing, and balancing acne-prone skin with regular use.

Praised for Calming Effects
Most customers love its calming effect due to blue tansy and soothing ingredients.
9.0

Excellent

Our Rating
7

THAYERS

Thayers Double Action Acne Serum with Salicylic Acid, Acne Treatment Face Serum with 2% Salicylic Acid and Niacinamide, Soothing and Non-Stripping Skin Care, 1 Fl Oz

18% Off
8.9

Very Good

Our Rating
8

SKIN1004
SKIN1004 Madagascar Centella Asiatica Ampoule Facial Serum 1.85 fl.oz, 55ml, Soothes Acne Prone and Sensitive Skin
Main highlights

Soothing and Hydrating Formula
Contains Madagascan Centella asiatica, known for high soothing actives, calms and hydrates sensitive skin.

Best for Mild Acne and Redness
Ideal for calming mild acne breakouts and reducing skin redness.

Praised for Skin Barrier Support
Customers appreciate its ability to support and soothe the skin barrier.
8.8

Very Good

Our Rating

9.1
worth the money

8.7
Aroma

8.4
For Gentle skin
9

CeraVe
CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz

21% Off
Main highlights

Advanced Exfoliation and Hydration
Combines BHA and AHA to clear acne, smooth skin, and maintain moisture.

Ideal for Sensitive and Acne-Prone Skin
Perfect for those seeking gentle yet effective acne treatment.

Unmatched Performance and Affordability
Praised for its effective results and affordable price point.
8.7

Very Good

Our Rating

8.9
worth the money

8.9
For Gentle skin

8.7
Aroma
10

Cetaphil
Cetaphil Gentle Clear Triple-Action Acne Treatment Serum with Salicylic Acid, Treats and Prevents Acne, Great for Post-Acne Marks, for All Skin Types, 1oz

33% Off
Main highlights

Triple Action Benefits
Treats current acne, prevents future breakouts, and reduces post-acne marks.

Ideal for Sensitive Skin
Gentle formulation, perfect for sensitive skin needing acne treatment.

Economical Use
A little goes a long way, praised for effectiveness.
8.6

Very Good

Our Rating

9.5
For Gentle skin

9.1
Moisturizing

8.9
Aroma

10 Best acne serums of 2025

1

La Roche-Posay Effaclar Salicylic Acid Treatment to Minimize Pores, Clear Acne Blemishes and Post Acne Marks

8.9

8.2

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

CeraVe Resurfacing Retinol Serum For Post Acne Marks, Formulated With Licorice Root Extract & Niacinamide, Brightening Serum & Pore Minimizer For Face, Post Acne Skin Barrier Repair, Non-Comedogenic

8.9

8.9

8.7

3

The Ordinary Salicylic Acid 2% Solution, Acne-Fighting Serum for Blemish-Prone Skin, 1 Fl Oz

4

Good Molecules Niacinamide Serum - 10% Niacinamide Balancing B3 Facial Serum for Acne, Tone, Texture - Brightening and Hydrating Skincare for Face

5

The Ordinary Niacinamide 10% + Zinc 1%, Smoothing Serum for Blemish-Prone Skin, 1 Fl Oz

6

BYOMA Clarifying Serum - Barrier Repair Serum - Clarifying Facial Serum for Acne Prone Skin - Calming Face Serum with Ceramides, Blue Tansy, PHA & Zinc - Balanced & Healthy Skin - 1.01 fl. oz

7

Thayers Double Action Acne Serum with Salicylic Acid, Acne Treatment Face Serum with 2% Salicylic Acid and Niacinamide, Soothing and Non-Stripping Skin Care, 1 Fl Oz

8

SKIN1004 Madagascar Centella Asiatica Ampoule Facial Serum 1.85 fl.oz, 55ml, Soothes Acne Prone and Sensitive Skin

9.1

8.7

8.4

9

CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz

8.9

8.9

8.7

10

Cetaphil Gentle Clear Triple-Action Acne Treatment Serum with Salicylic Acid, Treats and Prevents Acne, Great for Post-Acne Marks, for All Skin Types, 1oz

9.5

9.1

8.9

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