10 Best acid reflux medicines of 2025

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1

REFLUX GOURMET
REFLUX GOURMET Natural Heartburn Acid Reflux Relief Support Supplement for GERD, LPR, Indigestion, Aid for Intermittent Fasting, Alginate Therapy, Made in The USA, Vanilla Caramel
Main highlights

Natural Relief and Safe Ingredients
All-natural supplement for heartburn relief, free from glycerin, potassium, and parabens, safe for children and pregnancy.

Versatile Use for Reflux and Fasting
Ideal for those seeking relief from reflux, GERD, LPR, and hunger pains during intermittent fasting.

Customer Praised Taste and Effectiveness
Praised for effective relief and pleasant taste, with flavors like Vanilla Caramel and Mint Chocolate.
Key specs
- Form:Supplement
- Use:Heartburn relief
- Active Ingredient:Alginate
- Dosage:One teaspoon
- Relief Duration:N/A
9.8

Exceptional

Our Rating

9.7
Simple to use

9.5
simple to consume

9.3
Flavor
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Value for Money

2

GoodSense
GoodSense Omeprazole Delayed Release Tablets 20 mg, Stomach Acid Reducer for Frequent Heartburn Treatment, 42 Count
Main highlights

Heartburn Treatment Efficiency
Omeprazole 20 mg reduces stomach acid for frequent heartburn relief.

Ideal for Frequent Heartburn
Best for those experiencing heartburn at least twice weekly.

User Satisfaction
Customers praise its consistent effectiveness in heartburn relief.
9.7

Exceptional

Our Rating

9.9
simple to consume

9.3
worth the money

9.3
Flavor
3

Amazon Basic Care
Amazon Basic Care Maximum Strength Famotidine Tablets 20 mg, Acid Reducer Pills for Heartburn Relief, 200 Count (Packaging may vary)
Main highlights

Effective Heartburn Relief
Contains 20 mg famotidine, reduces heartburn for up to 12 hours.

Ideal for Nighttime Use
Prevents nighttime indigestion when taken before bedtime.

Cost-Effective Alternative
Customers praise value, comparable effectiveness to name brands.
9.6

Exceptional

Our Rating

9.9
simple to consume

9.3
worth the money

9.1
Flavor
4

Amazon Basic Care
Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1) (Packaging may vary)
Main highlights

Effective Acid Reduction
Omeprazole 20 mg reduces stomach acid, treating frequent heartburn occurring twice a week or more.

Recommended for Regular Heartburn Sufferers
Ideal for those experiencing heartburn at least twice weekly, requiring a 14-day treatment.

Cost-Effective Prilosec Alternative
Praised for affordability and effectiveness compared to Prilosec, offering great value.
9.4

Excellent

Our Rating

9.9
simple to consume

9.3
Flavor

9.3
worth the money
5

Amazon Basic Care
Amazon Basic Care Esomeprazole Magnesium Delayed Release Capsules, 20 mg, Acid Reducer, Heartburn Medicine, 42 Count
Main highlights

Effective Acid Reducer
Contains esomeprazole 20 mg, clinically proven to treat frequent heartburn.

Ideal for Frequent Heartburn
Best for those experiencing heartburn 2 or more days a week.

Cost-Effective Alternative
Praised for being as effective as Nexium but more affordable.
9.3

Excellent

Our Rating

9.5
simple to consume

8.4
worth the money
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6

Ohm
Ohm Omeprazole 20mg, 42 Delayed-Release Tablets, Acid Reducer for Frequent Heartburn, 24-Hour Relief Heartburn Medicine, Helps Relieve Stomach & Chest Discomfort (6 Weeks of Supply, 42, Count)
Main highlights

Effective Stomach Acid Reduction
Ohm Omeprazole Tablets provide effective relief from frequent heartburn by reducing stomach acid with delayed-release technology.

Ideal for Regular Use
Perfect for individuals needing consistent heartburn management, offering three 14-day treatment courses in one package.

Easy Swallowing Experience
Customers appreciate the coated tablets for being easier to swallow compared to capsules.
9.2

Excellent

Our Rating
7

HealthCareAisle
HealthCareAisle Omeprazole 20 mg, 42 Delayed-Release Capsules - Acid Reducer, Treats Frequent Heartburn, 42 Count (Pack of 1)
Main highlights

Effective Heartburn Relief
Omeprazole 20mg capsules provide 24-hour relief from frequent heartburn.

Best for Frequent Heartburn
Ideal for individuals experiencing heartburn 2 or more days a week.

Affordable Alternative
Customers praise its cost-effectiveness compared to brand-name products.
8.9

Very Good

Our Rating
8

Boiron
Boiron Acidil for Relief of Acid Reflux, Heartburn, Indigestion, and Upset Stomach - 60 Count

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Main highlights

Natural and Fast Relief
Boiron Acidil provides fast-acting relief from acid reflux, heartburn, and indigestion naturally.

Best for Mild Symptoms
Ideal for mild to moderate digestive discomforts, perfect for everyday use.

Quick-Dissolving Tablets
Customers appreciate the quick-dissolving tablets that work within minutes.
8.7

Very Good

Our Rating

8.0
Flavor

8.0
worth the money
9

Glenmark Therapeutics
Glenmark Maximum Strength Famotidine Tablets, 20 mg, Acid Reducer for Heartburn Relief, 200 Count
Main highlights

Effective Acid Reducer
Includes 20 mg of Famotidine for quick heartburn relief.

Ideal for Frequent Heartburn
Perfect for those experiencing frequent heartburn or indigestion.

Highly Praised Affordability
Praised for its cost-effectiveness compared to name brands.
8.6

Very Good

Our Rating

9.9
simple to consume

9.3
worth the money
10

Curist
Curist Famotidine 20mg Bulk Pack (300 Count Tablets) Acid Reflux Medicine for Heartburn Relief - OTC Maximum Strength Stomach Acid Reducer - Anti Acid Relief Tablets for Indigestion Heartburn Relief
Main highlights

Effective Relief and Prevention
Provides quick heartburn relief and lasting protection against stomach acid.

Convenient for Meal-Induced Heartburn
Ideal for preventing heartburn from specific foods and beverages.

Great Value and Performance
Praised for excellent value and comparable effectiveness to name brands.
Key specs
- Form:Tablets
- Use:Acid reflux relief
- Active Ingredient:Famotidine 20mg
- Dosage:20mg
- Relief Duration:Lasting protection
8.5

Good

Our Rating

10 Best acid reflux medicines of 2025

1

REFLUX GOURMET Natural Heartburn Acid Reflux Relief Support Supplement for GERD, LPR, Indigestion, Aid for Intermittent Fasting, Alginate Therapy, Made in The USA, Vanilla Caramel

9.7

9.5

9.3

How do we rank?

How do we rank?

Analyzing top stores

2

GoodSense Omeprazole Delayed Release Tablets 20 mg, Stomach Acid Reducer for Frequent Heartburn Treatment, 42 Count

9.9

9.3

9.3

3

Amazon Basic Care Maximum Strength Famotidine Tablets 20 mg, Acid Reducer Pills for Heartburn Relief, 200 Count (Packaging may vary)

9.9

9.3

9.1

4

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1) (Packaging may vary)

9.9

9.3

9.3

5

Amazon Basic Care Esomeprazole Magnesium Delayed Release Capsules, 20 mg, Acid Reducer, Heartburn Medicine, 42 Count

9.5

8.4

6

Ohm Omeprazole 20mg, 42 Delayed-Release Tablets, Acid Reducer for Frequent Heartburn, 24-Hour Relief Heartburn Medicine, Helps Relieve Stomach & Chest Discomfort (6 Weeks of Supply, 42, Count)

7

HealthCareAisle Omeprazole 20 mg, 42 Delayed-Release Capsules - Acid Reducer, Treats Frequent Heartburn, 42 Count (Pack of 1)

8

Boiron Acidil for Relief of Acid Reflux, Heartburn, Indigestion, and Upset Stomach - 60 Count

8.0

8.0

9

Glenmark Maximum Strength Famotidine Tablets, 20 mg, Acid Reducer for Heartburn Relief, 200 Count

9.9

9.3

10

Curist Famotidine 20mg Bulk Pack (300 Count Tablets) Acid Reflux Medicine for Heartburn Relief - OTC Maximum Strength Stomach Acid Reducer - Anti Acid Relief Tablets for Indigestion Heartburn Relief

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