10 Best zinc oxide ointments of 2025

Save up to 40% off

Best Choice

1

Nivagen
Nivagen Zinc Oxide Ointment USP 20% | For Diaper Rash, Chafed Skin, Protects From Wetness, Relief From Poison Ivy, Poison Oak, & Poison Sumac | 15oz Jar Of Zinc Oxide
Main highlights

Key Features and Benefits
Fast-acting formula with Zinc Oxide for immediate relief from diaper rash, chafing, and chapped skin; safe for all ages and daily use.

Ideal Use Cases
Perfect for preventing skin discomfort due to diaper rash, minor burns, insect bites, and irritation from poison ivy, oak, and sumac.

Customer Reviews Highlight
Most praised for its quick effectiveness in healing and providing a protective barrier, making it a must-have for parents and outdoor enthusiasts.
9.9

Exceptional

Our Rating
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Globe
16 oz Globe Zinc Oxide 20% Skin Protectant Barrier Ointment, Treatment for Diaper Rash, Relief From Poison Ivy, Sumac & Oak, Protects From Wetness, Protects Chafed Skin
Main highlights

Key Features and Benefits
Fast-acting, zinc oxide-based cream provides broad-spectrum protection and relief, in a market-leading 16 oz size for diaper rash treatment.

Ideal Use Cases
Exceptional for treating and preventing diaper rash, and offering soothing relief from poison ivy, oak, and sumac symptoms.

Customer Reviews Highlight
Most praised for its effectiveness in rapid relief and prevention of diaper rash, making it a favorite among parents.
9.7

Exceptional

Our Rating
3

CareAll

CareAll Zinc Oxide 20% Skin Protectant Barrier Ointment 2 oz (3 Pack), Relieves, Treats and Prevents Minor Skin Irritations due to Diaper Rash. Helps Seal Out Wetness. Protects Chafed Skin.
9.6

Exceptional

Our Rating
4

CareAll

CareAll Zinc Oxide 20% Skin Protectant Barrier Ointment 15 oz., Provides Relief, Prevention and Treatment for Chafing due to Diaper Rash. Helps Seal Out Wetness. Non-Nano.

32% Off
9.5

Excellent

Our Rating

9.3
Easy to use

9.1
worth the money
5

Dynarex
Dynarex Zinc Oxide Ointment, Soothes, Prevents, and Relieves Diaper Rash, Chaffed Skin, and Irritation, White, 1 Count - 15 oz. Jar of Ointment

38% Off
Main highlights

Protective Skin Barrier
Dynarex Zinc Oxide Ointment provides a protective barrier to prevent diaper rash and chafing, offering soothing relief and irritation prevention.

Ideal for Diaper Rash
Apply liberally on clean, dry skin to prevent and treat diaper rash effectively with each diaper change.

Customer Praises Soothing Relief
Users frequently commend the immediate soothing relief provided by the ointment, especially for irritated and inflamed skin.
9.2

Excellent

Our Rating
See Today’s Deals & Prices
6

Desitin
Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide for Treatment, Relief & Prevention, Hypoallergenic, Phthalate- & Paraben-Free Paste, Protects Skin for 12 Hours, 4.8 oz

32% Off
Main highlights

Maximum Strength Relief
Desitin's 40% zinc oxide formula provides up to 12-hour protection and healing for diaper rash.

Ideal for Sensitive Skin
Hypoallergenic and free of parabens, phthalates, dyes, and soap, perfect for daily use on baby's sensitive skin.

Highly Recommended by Users
Praised for its effectiveness, forming a protective barrier and soothing chafed skin quickly.
Key specs
- Size:4.8-ounce tube
- Formulation:Paraben-free, dye-free
- Ingredients:40% zinc oxide
- Features:5-in-1 action
- Protection:Up to 12 hours
9.1

Excellent

Our Rating

9.7
Simple to use

9.5
Easy to use

9.5
Comfort
7

Medline Remedy
Medline Remedy Essentials Zinc Oxide Skin Protectant Paste (4 oz Tube), Unscented, Barrier, Incontinence Cream, Diaper Rash, Adults, Elderly, Hypoallergenic, Paraben Free
Main highlights

Effective Wetness Defense
Contains 75% petrolatum and 20% zinc oxide for robust skin protection.

Versatile Use Cases
Ideal for diaper rash, incontinence, chafing, and minor skin irritations.

Praised Barrier Cream
Highly recommended by customers for its reliable protective barrier.
8.9

Very Good

Our Rating
8

TenderGentle
Zinc Oxide Ointment for Adults and Babies - 1 oz Diaper Rash Ointment - Skin Protectant for Diaper Rashes, Cuts, and Burns - 20% Zinc Oxide
Main highlights

Zinc Oxide Protection
Contains 20% zinc oxide to protect and heal skin.

Versatile Use Cases
Ideal for diaper rashes, poison ivy, oak, and sumac.

Customer Praised Effectiveness
Praised for quick relief and soothing properties.
Key specs
- Size:1 oz. tube
- Formulation:Ointment
- Ingredients:20% zinc oxide
- Features:Aids skin, diaper rash
- Protection:Skin protectant
8.8

Very Good

Our Rating
9

TenderGentle

Zinc Oxide Ointment for Adults and Babies - 2 oz Diaper Rash Ointment - Skin Protectant for Diaper Rashes, Cuts, and Burns - 20% Zinc Oxide
8.7

Very Good

Our Rating
10

Globe Pharmacy

(2 Pack) Globe Zinc Oxide Ointment 20%, 2 Ounce Tube (Total 4 oz) Advanced Skin Protection, For Diaper Rash, Relief From Poison Ivy, Sumac & Oak, Protects From Wetness, Protects Chafed Skin

40% Off
8.6

Very Good

Our Rating

10 Best zinc oxide ointments of 2025

1

Nivagen Zinc Oxide Ointment USP 20% | For Diaper Rash, Chafed Skin, Protects From Wetness, Relief From Poison Ivy, Poison Oak, & Poison Sumac | 15oz Jar Of Zinc Oxide

How do we rank?

How do we rank?

Analyzing top stores

2

16 oz Globe Zinc Oxide 20% Skin Protectant Barrier Ointment, Treatment for Diaper Rash, Relief From Poison Ivy, Sumac & Oak, Protects From Wetness, Protects Chafed Skin

3

CareAll Zinc Oxide 20% Skin Protectant Barrier Ointment 2 oz (3 Pack), Relieves, Treats and Prevents Minor Skin Irritations due to Diaper Rash. Helps Seal Out Wetness. Protects Chafed Skin.

4

CareAll Zinc Oxide 20% Skin Protectant Barrier Ointment 15 oz., Provides Relief, Prevention and Treatment for Chafing due to Diaper Rash. Helps Seal Out Wetness. Non-Nano.

9.3

9.1

5

Dynarex Zinc Oxide Ointment, Soothes, Prevents, and Relieves Diaper Rash, Chaffed Skin, and Irritation, White, 1 Count - 15 oz. Jar of Ointment

6

Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide for Treatment, Relief & Prevention, Hypoallergenic, Phthalate- & Paraben-Free Paste, Protects Skin for 12 Hours, 4.8 oz

9.7

9.5

9.5

7

Medline Remedy Essentials Zinc Oxide Skin Protectant Paste (4 oz Tube), Unscented, Barrier, Incontinence Cream, Diaper Rash, Adults, Elderly, Hypoallergenic, Paraben Free

8

Zinc Oxide Ointment for Adults and Babies - 1 oz Diaper Rash Ointment - Skin Protectant for Diaper Rashes, Cuts, and Burns - 20% Zinc Oxide

9

Zinc Oxide Ointment for Adults and Babies - 2 oz Diaper Rash Ointment - Skin Protectant for Diaper Rashes, Cuts, and Burns - 20% Zinc Oxide

10

(2 Pack) Globe Zinc Oxide Ointment 20%, 2 Ounce Tube (Total 4 oz) Advanced Skin Protection, For Diaper Rash, Relief From Poison Ivy, Sumac & Oak, Protects From Wetness, Protects Chafed Skin

Sign up and get exclusive special deals