9 Best topical antimicrobials of 2026

Save up to 36% off

1

Neosporin
Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Soothing Infection Protection & Wound Care of Minor Cuts, Scrapes & Burns, 1 oz

19% Off
Main highlights

24-Hour Infection Protection
Contains neomycin and polymyxin B for continuous infection defense.

Versatile Use for Humans and Pets
Ideal for treating scrapes and wounds on both humans and pets.

Easy Application and Short-term Numbing
Praised for its easy application and immediate, though brief, numbing effect.
Key specs
- Active Ingredients:Neomycin, polymyxin B
- Usage:Infection prevention, pain relief
- Formulation:Ointment
- Packaging:Tube
- Country of Origin:USA
9.9

Exceptional

Our Rating

9.7
Simple to use

9.5
pain management

9.1
worth the money
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2

Neosporin
Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Soothing Infection Protection & Wound Care of Minor Cuts, Scrapes & Burns, 1 oz

23% Off
Main highlights

24-Hour Infection Protection
Contains neomycin and polymyxin B for continuous infection defense.

Versatile Use for Humans and Pets
Ideal for treating scrapes and wounds on both humans and pets.

Easy Application and Short-term Numbing
Praised for its easy application and immediate, though brief, numbing effect.
Key specs
- Active Ingredients:Neomycin, polymyxin B
- Usage:Infection prevention, pain relief
- Formulation:Ointment
- Packaging:Tube
- Country of Origin:USA
9.8

Exceptional

Our Rating

9.7
Simple to use

9.5
pain management

9.1
worth the money
3

Globe
Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to The Active Ingredients of The Leading Brand.
Main highlights

Infection Protection
Provides 24-hour protection against infections in minor cuts, scrapes, and burns.

First Aid Essential
Ideal for first aid kits and treating minor injuries at home or on the go.

Customer Praised Value
Praised for identical ingredients and effectiveness as leading brands at a lower price.
Key specs
- Active Ingredients:Neomycin, Bacitracin, Polymyxin
- Usage:First aid for cuts
- Volume:4 oz total
- Formulation:Ointment
- Packaging:4 single 1 oz tubes
9.6

Exceptional

Our Rating

9.7
Simple to use

9.5
worth the money
4

Globe
Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to The Active Ingredients of The Leading Brand.
Main highlights

Infection Protection
Provides 24-hour protection against infections in minor cuts, scrapes, and burns.

First Aid Essential
Ideal for first aid kits and treating minor injuries at home or on the go.

Customer Praised Value
Praised for identical ingredients and effectiveness as leading brands at a lower price.
Key specs
- Active Ingredients:Neomycin, Bacitracin, Polymyxin
- Usage:First aid for cuts
- Volume:4 oz total
- Formulation:Ointment
- Packaging:4 single 1 oz tubes
9.4

Excellent

Our Rating

9.7
Simple to use

9.5
worth the money
5

CareAll
CareAll Triple Antibiotic Ointment (25 Pack), 0.9gr Foil Packet. First Aid Ointment That Prevents Infection in Minor Scrapes, Cuts, and Burns
Main highlights

Antibiotic Ointment Formulation
FIRST AID ANTIBIOTIC OINTMENT for the prevention of infections in minor cuts, scrapes and burns. Formulated to be phthalate-free, paraben-free, dye-free, and fragrance-free.

Ideal for Travel and First Aid Kits
SINGLE USE each 0.9 gram foil packet is easy to dispense. Perfect for travel, glove compartments, first aid kits in homes, cars, workshops, and workplaces.

Convenient Single Use Packets
Customers frequently praise the convenience of the single-use packets, noting they are perfect for travel, first aid kits, and on-the-go situations.
Key specs
- Active Ingredients:Bacitracin Zinc, Neomycin, Polymyxin B
- Usage:First aid antibiotic
- Volume:0.9 gram
- Formulation:N/A
- Packaging:N/A
9.3

Excellent

Our Rating

9.9
movability

9.9
dispense easily

9.7
worth the money
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6

Band-Aid
Band-Aid Brand Pain Relieving Antiseptic Cleansing Spray, Pramoxine HCl, 8 fl. Oz

24% Off
Main highlights

Pain Relief and Germ Protection
Contains pramoxine HCl for pain relief and benzalkonium Cl to kill germs.

Ideal for Minor Wounds
Perfect for cleaning and relieving pain from cuts, scrapes, and burns.

Highly Trusted Brand
Praised for quality and effectiveness by users and doctors alike.
Key specs
- Active Ingredients:Pramoxine HCl, Benzalkonium Cl
- Usage:Clean minor wounds
- Volume:8-fluid ounce
- Formulation:N/A
- Packaging:N/A
9.2

Excellent

Our Rating

9.7
Simple to use

9.3
materials Quality

8.4
pain management
7

Band-Aid
Band-Aid Brand Pain Relieving Antiseptic Cleansing Spray, Pramoxine HCl, 8 fl. Oz

28% Off
Main highlights

Pain Relief and Germ Protection
Contains pramoxine HCl for pain relief and benzalkonium Cl to kill germs.

Ideal for Minor Wounds
Perfect for cleaning and relieving pain from cuts, scrapes, and burns.

Highly Trusted Brand
Praised for quality and effectiveness by users and doctors alike.
Key specs
- Active Ingredients:Pramoxine HCl, Benzalkonium Cl
- Usage:Clean minor wounds
- Volume:8-fluid ounce
- Formulation:N/A
- Packaging:N/A
9.1

Excellent

Our Rating

9.7
Simple to use

9.3
materials Quality

8.4
pain management
8

neosporin
Neosporin Original First Aid Triple Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Helps Minimize The Appearance of Scars for Minor Wounds, .5 oz

33% Off
Main highlights

24-Hour Infection Protection
Neosporin Original provides 24-hour infection protection for minor cuts, scrapes, and burns with its powerful antibiotic formula.

Ideal for Minor Wounds
Perfect for treating minor cuts, scrapes, and burns, ensuring quick and effective healing.

Highly Praised for Effectiveness
Customers frequently praise its effectiveness and ease of use for minor emergencies.
Key specs
- Active Ingredients:neomycin sulfate, bacitracin zinc, polymyxin B
- Usage:Apply 1 to 3 times daily
- Formulation:Ointment
- Packaging:Tube
- Country of Origin:USA
9.0

Excellent

Our Rating

9.9
For Gentle skin

9.7
Simple to use

9.7
For traveling
9

neosporin
Neosporin Original First Aid Triple Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Helps Minimize The Appearance of Scars for Minor Wounds, .5 oz

36% Off
Main highlights

24-Hour Infection Protection
Neosporin Original provides 24-hour infection protection for minor cuts, scrapes, and burns with its powerful antibiotic formula.

Ideal for Minor Wounds
Perfect for treating minor cuts, scrapes, and burns, ensuring quick and effective healing.

Highly Praised for Effectiveness
Customers frequently praise its effectiveness and ease of use for minor emergencies.
Key specs
- Active Ingredients:neomycin sulfate, bacitracin zinc, polymyxin B
- Usage:Apply 1 to 3 times daily
- Formulation:Ointment
- Packaging:Tube
- Country of Origin:USA
8.9

Very Good

Our Rating

9.9
For Gentle skin

9.7
Simple to use

9.7
For traveling

9 Best topical antimicrobials of 2026

1

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Soothing Infection Protection & Wound Care of Minor Cuts, Scrapes & Burns, 1 oz

9.7

9.5

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Soothing Infection Protection & Wound Care of Minor Cuts, Scrapes & Burns, 1 oz

9.7

9.5

9.1

3

Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to The Active Ingredients of The Leading Brand.

9.7

9.5

4

Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to The Active Ingredients of The Leading Brand.

9.7

9.5

5

CareAll Triple Antibiotic Ointment (25 Pack), 0.9gr Foil Packet. First Aid Ointment That Prevents Infection in Minor Scrapes, Cuts, and Burns

9.9

9.9

9.7

6

Band-Aid Brand Pain Relieving Antiseptic Cleansing Spray, Pramoxine HCl, 8 fl. Oz

9.7

9.3

8.4

7

Band-Aid Brand Pain Relieving Antiseptic Cleansing Spray, Pramoxine HCl, 8 fl. Oz

9.7

9.3

8.4

8

Neosporin Original First Aid Triple Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Helps Minimize The Appearance of Scars for Minor Wounds, .5 oz

9.9

9.7

9.7

9

Neosporin Original First Aid Triple Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Helps Minimize The Appearance of Scars for Minor Wounds, .5 oz

9.9

9.7

9.7

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