10 Best topical antimicrobials of 2026

Save up to 31% off

Best Choice

1

Neosporin
Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Wound Care of Minor Cuts, Scrapes and Burns, Polymyxin B & Pramoxine HCl, 1 oz

20% Off
Main highlights

24-Hour Infection Protection
Contains neomycin and polymyxin B for continuous infection defense.

Versatile Use for Humans and Pets
Ideal for treating scrapes and wounds on both humans and pets.

Easy Application and Short-term Numbing
Praised for its easy application and immediate, though brief, numbing effect.
Key specs
- Active Ingredients:Neomycin, polymyxin B
- Usage:Infection prevention, pain relief
- Formulation:Ointment
- Packaging:Tube
- Country of Origin:USA
9.9

Exceptional

Our Rating

9.7
Simple to use

9.5
pain management

9.1
worth the money
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Value for Money

2

Neosporin
Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Wound Care of Minor Cuts, Scrapes and Burns, Polymyxin B & Pramoxine HCl, 1 oz

24% Off
Main highlights

24-Hour Infection Protection
Contains neomycin and polymyxin B for continuous infection defense.

Versatile Use for Humans and Pets
Ideal for treating scrapes and wounds on both humans and pets.

Easy Application and Short-term Numbing
Praised for its easy application and immediate, though brief, numbing effect.
Key specs
- Active Ingredients:Neomycin, polymyxin B
- Usage:Infection prevention, pain relief
- Formulation:Ointment
- Packaging:Tube
- Country of Origin:USA
9.8

Exceptional

Our Rating

9.7
Simple to use

9.5
pain management

9.1
worth the money
3

neosporin
Neosporin Original First Aid Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes and Burns,.5 oz

28% Off
Main highlights

24-Hour Infection Protection
Neosporin Original provides 24-hour infection protection for minor cuts, scrapes, and burns with its powerful antibiotic formula.

Ideal for Minor Wounds
Perfect for treating minor cuts, scrapes, and burns, ensuring quick and effective healing.

Highly Praised for Effectiveness
Customers frequently praise its effectiveness and ease of use for minor emergencies.
Key specs
- Active Ingredients:neomycin sulfate, bacitracin zinc, polymyxin B
- Usage:Apply 1 to 3 times daily
- Formulation:Ointment
- Packaging:Tube
- Country of Origin:USA
9.7

Exceptional

Our Rating

9.9
For Gentle skin

9.7
Simple to use

9.7
For traveling
4

neosporin
Neosporin Original First Aid Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes and Burns,.5 oz

31% Off
Main highlights

24-Hour Infection Protection
Neosporin Original provides 24-hour infection protection for minor cuts, scrapes, and burns with its powerful antibiotic formula.

Ideal for Minor Wounds
Perfect for treating minor cuts, scrapes, and burns, ensuring quick and effective healing.

Highly Praised for Effectiveness
Customers frequently praise its effectiveness and ease of use for minor emergencies.
Key specs
- Active Ingredients:neomycin sulfate, bacitracin zinc, polymyxin B
- Usage:Apply 1 to 3 times daily
- Formulation:Ointment
- Packaging:Tube
- Country of Origin:USA
9.6

Exceptional

Our Rating

9.9
For Gentle skin

9.7
Simple to use

9.7
For traveling
5

Neosporin
Neosporin Original First Aid Triple Antibiotic Ointment, Bacitracin Zinc & Neomycin Sulfate Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes & Burns, 1 oz
Main highlights

24-Hour Infection Protection
Neosporin provides 24-hour protection against infections for minor wounds.

Ideal for Minor Cuts and Scrapes
Perfect for treating minor cuts, scrapes, and burns quickly.

Convenient Size
Highly portable and easy to store, praised by users.
Key specs
- Active Ingredients:neomycin sulfate, bacitracin zinc, polymyxin B
- Usage:Treats minor cuts, scrapes
- Formulation:Topical ointment
- Packaging:1-ounce tube
- Country of Origin:USA
9.5

Excellent

Our Rating

9.9
quality of ingredients

9.7
worth the money

9.7
Simple to use
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6

Neosporin
Neosporin Original First Aid Triple Antibiotic Ointment, Bacitracin Zinc & Neomycin Sulfate Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes & Burns, 1 oz
Main highlights

24-Hour Infection Protection
Neosporin provides 24-hour protection against infections for minor wounds.

Ideal for Minor Cuts and Scrapes
Perfect for treating minor cuts, scrapes, and burns quickly.

Convenient Size
Highly portable and easy to store, praised by users.
Key specs
- Active Ingredients:neomycin sulfate, bacitracin zinc, polymyxin B
- Usage:Treats minor cuts, scrapes
- Formulation:Topical ointment
- Packaging:1-ounce tube
- Country of Origin:USA
9.4

Excellent

Our Rating

9.9
quality of ingredients

9.7
worth the money

9.7
Simple to use
7

Globe
Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to The Active Ingredients of The Leading Brand.
Main highlights

Infection Protection
Provides 24-hour protection against infections in minor cuts, scrapes, and burns.

First Aid Essential
Ideal for first aid kits and treating minor injuries at home or on the go.

Customer Praised Value
Praised for identical ingredients and effectiveness as leading brands at a lower price.
Key specs
- Active Ingredients:Neomycin, Bacitracin, Polymyxin
- Usage:First aid for cuts
- Volume:4 oz total
- Formulation:Ointment
- Packaging:4 single 1 oz tubes
9.2

Excellent

Our Rating

9.7
Simple to use

9.5
worth the money
8

Globe
Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to The Active Ingredients of The Leading Brand.
Main highlights

Infection Protection
Provides 24-hour protection against infections in minor cuts, scrapes, and burns.

First Aid Essential
Ideal for first aid kits and treating minor injuries at home or on the go.

Customer Praised Value
Praised for identical ingredients and effectiveness as leading brands at a lower price.
Key specs
- Active Ingredients:Neomycin, Bacitracin, Polymyxin
- Usage:First aid for cuts
- Volume:4 oz total
- Formulation:Ointment
- Packaging:4 single 1 oz tubes
9.0

Excellent

Our Rating

9.7
Simple to use

9.5
worth the money
9

Thera Care
Thera|Care Triple Antibiotic Ointment | First Aid | Infection Prevention and Protection | 1.0 oz | Topical Wound Care for Minor Scrapes and Cuts
Main highlights

Long-lasting Protection
Provides extended protection against infections for minor cuts, scrapes, and burns with antibiotic ointment.

Ideal for Minor Wounds
Perfect for treating minor scrapes, cuts, and fresh piercings, aiding in faster healing.

Highly Praised Effectiveness
Customers commend its efficiency in healing and preventing infections effectively.
Key specs
- Active Ingredients:Bacitracin Zinc
- Usage:Treats minor cuts, scrapes
- Formulation:Ointment
- Packaging:1.0 oz. tube
- Country of Origin:India
8.8

Very Good

Our Rating
10

Thera Care
Thera|Care Triple Antibiotic Ointment | First Aid | Infection Prevention and Protection | 1.0 oz | Topical Wound Care for Minor Scrapes and Cuts
Main highlights

Long-lasting Protection
Provides extended protection against infections for minor cuts, scrapes, and burns with antibiotic ointment.

Ideal for Minor Wounds
Perfect for treating minor scrapes, cuts, and fresh piercings, aiding in faster healing.

Highly Praised Effectiveness
Customers commend its efficiency in healing and preventing infections effectively.
Key specs
- Active Ingredients:Bacitracin Zinc
- Usage:Treats minor cuts, scrapes
- Formulation:Ointment
- Packaging:1.0 oz. tube
- Country of Origin:India
8.6

Very Good

Our Rating

10 Best topical antimicrobials of 2026

1

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Wound Care of Minor Cuts, Scrapes and Burns, Polymyxin B & Pramoxine HCl, 1 oz

9.7

9.5

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Wound Care of Minor Cuts, Scrapes and Burns, Polymyxin B & Pramoxine HCl, 1 oz

9.7

9.5

9.1

3

Neosporin Original First Aid Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes and Burns,.5 oz

9.9

9.7

9.7

4

Neosporin Original First Aid Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes and Burns,.5 oz

9.9

9.7

9.7

5

Neosporin Original First Aid Triple Antibiotic Ointment, Bacitracin Zinc & Neomycin Sulfate Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes & Burns, 1 oz

9.9

9.7

9.7

6

Neosporin Original First Aid Triple Antibiotic Ointment, Bacitracin Zinc & Neomycin Sulfate Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes & Burns, 1 oz

9.9

9.7

9.7

7

Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to The Active Ingredients of The Leading Brand.

9.7

9.5

8

Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to The Active Ingredients of The Leading Brand.

9.7

9.5

9

Thera|Care Triple Antibiotic Ointment | First Aid | Infection Prevention and Protection | 1.0 oz | Topical Wound Care for Minor Scrapes and Cuts

10

Thera|Care Triple Antibiotic Ointment | First Aid | Infection Prevention and Protection | 1.0 oz | Topical Wound Care for Minor Scrapes and Cuts

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