10 Best systane lubricant eye gels of 2025

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Best Choice

1

Systane
Systane Lub Eye Nightime Ointment 3.5g (6 Pack) 0.12 Ounce(Packaging May Vary)

10% Off
Main highlights

Effective for Severe Dry Eyes
Contains 94% White Petrolatum and 3% Mineral Oil, providing long-lasting moisture and relief for extremely dry eyes. Ideal for nighttime use.

Ideal for Post-Eye Surgery Care
Perfect for individuals recovering from eye surgery or those with severe dry eyes. Provides overnight protection and moisture, ensuring comfort and healing.

Highly Praised for Long-Lasting Comfort
Customers appreciate the thick consistency and effectiveness, noting significant relief from dry eyes and improved comfort throughout the night.
9.8

Exceptional

Our Rating

9.5
Moisturizing

9.3
Simple to use

8.7
worth the money
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Value for Money

2

Systane
Systane Nighttime Lubricant Eye Ointment 3.50 g (Pack of 4)
Main highlights

Lubricates and Comforts Dry Eyes
Systane Nighttime Lubricant Eye Ointment provides rich, preservative-free lubrication, offering nighttime relief for dry eyes and preventing further irritation.

Ideal for Severe Dry Eye Relief
Perfect for individuals with severe dry eyes, especially those who need long-lasting overnight moisture and cannot use drops due to conditions like Rheumatoid Arthritis.

Highly Praised for Overnight Moisture
Customers consistently praise the product for keeping eyes lubricated overnight, preventing discomfort and dryness, and making mornings pain-free.
Key specs
- Use Case:Dry eyes relief
- Relief Duration:Nighttime relief
- Eye Comfort:Lubricates and comforts
- Packaging Type:4 Pack
- Moisturizing Formula:Rich ointment
9.5

Excellent

Our Rating

9.9
Simple to use

9.7
Moisturizing

9.5
pain management
3

Systane
Systane Lubricant Eye Gel Drops, 10-mL (Packaging May Vary)

16% Off
Main highlights

Long-Lasting Relief
Thicker formulation offers prolonged relief from dry eye discomfort.

Ideal for Night Use
Perfect for overnight use due to gel-like consistency.

Highly Praised Moisturization
Customers love the effective moisturization that lasts through the night.
Key specs
- Use Case:Dryness of the eye
- Relief Duration:Temporary relief
- Eye Comfort:Protective shield
- Packaging Type:Product packaging may vary
- Moisturizing Formula:Thicker eye drop
9.2

Excellent

Our Rating

9.1
Simple to use

9.1
Moisturizing

8.9
Long life
4

Systane
Systane Lubricant Eye Gel, Nighttime, 0.35-Ounces (package may vary)

18% Off
Main highlights

Key Features
1 Dr Recommended Brand of Artificial Tears offers thickest gel for maximum dry eye protection, ensuring long-lasting, nighttime relief.

Ideal Use Cases
Perfect for individuals suffering from severe dryness and irritation, providing exceptional relief during sleep and in dry, challenging environments.

Customer Reviews
Most praised for its effectiveness in significantly reducing dry eye symptoms, offering immediate and long-lasting comfort.
Key specs
- Use Case:Nighttime protection
- Relief Duration:Long-lasting, nighttime protection
- Eye Comfort:Burning and irritation relief
- Packaging Type:N/A
- Moisturizing Formula:Thickest gel formulation
9.0

Excellent

Our Rating

8.9
Moisturizing

8.4
Long life

8.2
worth the money
5

Systane
Systane Nighttime Lubricant Eye Ointment 3.5g Tube
Main highlights

Long-Lasting Protection
Forms a long-lasting, protective layer on eyes while you sleep, soothing and protecting against dryness and irritation.

Ideal for Nighttime Use
Best used for nighttime relief of dry eye symptoms, providing comfort and protection as you rest.

Soothing Effect
Most praised for its soothing effect, alleviating discomfort from dry eyes effectively.
Key specs
- Formula:Preservative-free
- Usage:Nighttime
- Preservatives:None
- Hydration:Soothes and protects
- Content:Ointment
8.8

Very Good

Our Rating
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6

Systane
Systane Lubricant Eye Gel Drops 10 ml, 2 Count
Main highlights

Convenient Gel Protection
Combines the convenience of a drop with the long-lasting protection of a gel, available in a pack of 2 for anytime use.

Ideal for Nighttime Use
Best used before bedtime due to temporary blurriness, providing long-lasting relief from dry eyes overnight.

Soothing and Long-Lasting
Praised for its soothing properties and long-lasting relief, especially beneficial for those with very dry eyes.
Key specs
- Use Case:Anytime protection
- Relief Duration:N/A
- Eye Comfort:N/A
- Packaging Type:Pack of 2
- Moisturizing Formula:N/A
8.7

Very Good

Our Rating

9.3
Simple to use

8.7
Easy to grip

8.7
Long life
7

Systane
Systane Nighttime Lubricant Eye Ointment 3.50 g (2 Pack) Lubricates and Comforts Dry Eyes Preservative-Free Rich Ointment for Nighttime Relief
Main highlights

Long-lasting Relief
Sterile gel drops offer extended dry-eye relief during sleep.

Nighttime Comfort
Perfect for use in windy, sunny conditions, or digital strain.

Customer Favorite Feature
Praised for its soothing, preservative-free formulation.
Key specs
- Use Case:Overnight dry eye relief
- Relief Duration:Long-lasting nighttime protection
- Eye Comfort:Restore comfort and relieve
- Packaging Type:4.25 x 3.27 x 0.75 inches
- Moisturizing Formula:Sterile gel drops
8.5

Good

Our Rating
8

Systane
Systane Lubricant Eye Ointment 3.5 g 1 Pack Canadian
Main highlights

Safe and Effective Formulation
Systane Nighttime Lubricant Eye Ointment is preservative-free, providing a safe and effective solution for nighttime dry eye relief.

Nighttime Dry Eye Relief
Ideal for use while sleeping, Systane Nighttime forms a smooth, comfortable protective layer to keep eyes lubricated and comfortable throughout the night.

Highly Effective for Severe Dry Eyes
Customers praise its effectiveness in relieving severe dry eyes, noting significant improvements in comfort and vision after regular nighttime use.
Key specs
- Use Case:Nighttime dry eye protection
- Relief Duration:Nighttime
- Eye Comfort:Smooth, protective layer
- Packaging Type:3.5g tubes
- Moisturizing Formula:Lubricant Eye Ointment
8.4

Good

Our Rating

9.7
Moisturizing

9.3
Simple to use

8.0
worth the money
9

Systane
Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

32% Off
Main highlights

Fast Long-Lasting Relief
Provides quick and extended relief for dry eye symptoms.

Ideal for On-the-Go Use
Perfect for soothing irritated eyes anytime, anywhere.

Highly Rated by Users
Praised for relieving dryness and reducing redness efficiently.
8.3

Good

Our Rating

9.5
Moisturizing

9.1
Long life

8.9
worth the money
10

Systane

Systane Gel Drops Lubricant Eye Gel, Anytime Protection, (0.33 oz (1 Pack) - 10 mL)

20% Off
8.0

Good

Our Rating

10 Best systane lubricant eye gels of 2025

1

Systane Lub Eye Nightime Ointment 3.5g (6 Pack) 0.12 Ounce(Packaging May Vary)

9.5

9.3

8.7

How do we rank?

How do we rank?

Analyzing top stores

2

Systane Nighttime Lubricant Eye Ointment 3.50 g (Pack of 4)

9.9

9.7

9.5

3

Systane Lubricant Eye Gel Drops, 10-mL (Packaging May Vary)

9.1

9.1

8.9

4

Systane Lubricant Eye Gel, Nighttime, 0.35-Ounces (package may vary)

8.9

8.4

8.2

5

Systane Nighttime Lubricant Eye Ointment 3.5g Tube

6

Systane Lubricant Eye Gel Drops 10 ml, 2 Count

9.3

8.7

8.7

7

Systane Nighttime Lubricant Eye Ointment 3.50 g (2 Pack) Lubricates and Comforts Dry Eyes Preservative-Free Rich Ointment for Nighttime Relief

8

Systane Lubricant Eye Ointment 3.5 g 1 Pack Canadian

9.7

9.3

8.0

9

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

9.5

9.1

8.9

10

Systane Gel Drops Lubricant Eye Gel, Anytime Protection, (0.33 oz (1 Pack) - 10 mL)

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