10 Best serum for acnes of 2025

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Best Choice

1

La Roche-Posay
La Roche-Posay Effaclar Salicylic Acid Treatment to Minimize Pores, Clear Acne Blemishes and Post Acne Marks
Main highlights

Pore Minimizing Salicylic Acid Formula
Effaclar's salicylic acid fights acne, minimizes pores, and smoothens skin.

Perfect for Humid Climates and Active Lifestyles
Ideal for those in humid environments or with active routines.

Praised for Immediate Acne Clearing
Customers love its fast action in reducing breakouts.
9.6

Exceptional

Our Rating

8.9
Light weight

8.2
Sheerness

8.0
worth the money
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Value for Money

2

medicube

medicube TXA+Niacinamide 15% Glow Facial Serum for After Spot Care | All-in-One Daily Korean Skincare | Uneven Skin Tone, Texture, and Hydration Care | High-Potency Tranexamic Acid 5% | 1.01 fl.oz

13% Off
9.4

Excellent

Our Rating
3

The Ordinary
The Ordinary Salicylic Acid 2% Solution, Acne-Fighting Serum for Blemish-Prone Skin, 1 Fl Oz
Main highlights

Blemish-Reduction Formula
The Ordinary Salicylic Acid 2% Solution targets acne and blemishes effectively.

Ideal for Oily Skin
Best used for oily and blemish-prone skin types.

Customer Praised Clarity
Users frequently commend its ability to clear skin blemishes.
9.1

Excellent

Our Rating
4

The Ordinary
The Ordinary Niacinamide 10% + Zinc 1%, Smoothing Serum for Blemish-Prone Skin, 1 Fl Oz
Main highlights

Potent Skin Smoothing Formula
The Ordinary Niacinamide 10% + Zinc 1% reduces blemishes and balances sebum production for clearer skin.

Ideal for Blemish-Prone Skin
Perfect for those with oily or acne-prone skin seeking a smoother complexion.

Highly Praised for Reducing Redness
Customers consistently commend its effectiveness in calming and reducing skin redness.
9.0

Excellent

Our Rating
5

CeraVe
CeraVe Resurfacing Retinol Serum For Post Acne Marks, Formulated With Licorice Root Extract & Niacinamide, Brightening Serum & Pore Minimizer For Face, Post Acne Skin Barrier Repair, Non-Comedogenic

15% Off
Main highlights

Smoother and Even-Toned Skin
Encapsulated retinol for smoother, more even skin tone.

Ideal for Sensitive Skin
Gentle formula suitable for sensitive, dry, and acne-prone skin.

User-Praised Texture Improvement
Notable improvement in skin texture and pore appearance.
Key specs
- Skin Type:Dry, sensitive, oily
- Formulation:Serum
- Effects:Brightening, calming
- Niacinamide:Yes
- Peptides:N/A
8.9

Very Good

Our Rating

8.9
Fashion

8.9
Aroma

8.7
worth the money
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6

SKIN1004
SKIN1004 Madagascar Centella Asiatica Ampoule Facial Serum 1.85 fl.oz, 55ml, Soothes Acne Prone and Sensitive Skin
Main highlights

Soothing and Hydrating Formula
Contains Madagascan Centella asiatica, known for high soothing actives, calms and hydrates sensitive skin.

Best for Mild Acne and Redness
Ideal for calming mild acne breakouts and reducing skin redness.

Praised for Skin Barrier Support
Customers appreciate its ability to support and soothe the skin barrier.
8.8

Very Good

Our Rating

9.1
worth the money

8.7
Aroma

8.4
For Gentle skin
7

Minimalist
Minimalist 10% Niacinamide Serum for Acne Control & Oil Balancing with Zinc | Pore Minimizer for Face | Clears Acne Marks & Blemishes for Even Skin Tone | For Women & Men | 1 Fl Oz / 30 ml

25% Off
Main highlights

Reduces Acne Marks & Blemishes
Clinically proven to reduce acne marks and dark spots in 2 weeks for an even complexion.

Ideal for Oily & Combination Skin
Perfect daily serum for oily or acne-prone skin, balancing oil and minimizing pores.

Praised for Softening Skin
Customers love its texture and how it softens and clears skin quickly.
8.7

Very Good

Our Rating
8

Good Molecules
Good Molecules Niacinamide Serum - 10% Niacinamide to Target Acne, Nourishment, and Skin Tone - Ultra Hydrating Serum and Brightening Skin Care for Face
Main highlights

Bright Healthy Complexion
Refines tone, improves texture, and nourishes skin with Niacinamide.

Ideal for Acne Prone Skin
Best for acne, uneven tone, enlarged pores, and dull texture.

Praised for Affordable Quality
Affordable, smooths skin, easy to use, and fragrance-free.
Key specs
- Skin Type:All, combination/oily
- Formulation:Serum
- Effects:Brighten, soothe, refine
- Niacinamide:10%
- Peptides:N/A
8.4

Good

Our Rating
9

BYOMA
BYOMA Clarifying Serum - Barrier Repair Serum - Clarifying Facial Serum for Acne Prone Skin - Calming Face Serum with Ceramides, Blue Tansy, PHA & Zinc - Balanced & Healthy Skin - 1.01 fl. oz
Main highlights

Barrier Boosting Benefits
Features Tri-Ceramide Complex with ceramides, cholesterol, and fatty acids to strengthen skin barrier.

Ideal for Acne Prone Skin
Perfect for calming, clearing, and balancing acne-prone skin with regular use.

Praised for Calming Effects
Most customers love its calming effect due to blue tansy and soothing ingredients.
Key specs
- Skin Type:All skin types
- Formulation:Serum
- Effects:Balances, calms, clears
- Niacinamide:N/A
- Peptides:Tri-Ceramide Complex
8.3

Good

Our Rating
10

THAYERS

Thayers Double Action Acne Serum with Salicylic Acid, Acne Treatment Face Serum with 2% Salicylic Acid and Niacinamide, Soothing and Non-Stripping Skin Care, 1 Fl Oz

32% Off
8.2

Good

Our Rating

10 Best serum for acnes of 2025

1

La Roche-Posay Effaclar Salicylic Acid Treatment to Minimize Pores, Clear Acne Blemishes and Post Acne Marks

8.9

8.2

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

medicube TXA+Niacinamide 15% Glow Facial Serum for After Spot Care | All-in-One Daily Korean Skincare | Uneven Skin Tone, Texture, and Hydration Care | High-Potency Tranexamic Acid 5% | 1.01 fl.oz

3

The Ordinary Salicylic Acid 2% Solution, Acne-Fighting Serum for Blemish-Prone Skin, 1 Fl Oz

4

The Ordinary Niacinamide 10% + Zinc 1%, Smoothing Serum for Blemish-Prone Skin, 1 Fl Oz

5

CeraVe Resurfacing Retinol Serum For Post Acne Marks, Formulated With Licorice Root Extract & Niacinamide, Brightening Serum & Pore Minimizer For Face, Post Acne Skin Barrier Repair, Non-Comedogenic

8.9

8.9

8.7

6

SKIN1004 Madagascar Centella Asiatica Ampoule Facial Serum 1.85 fl.oz, 55ml, Soothes Acne Prone and Sensitive Skin

9.1

8.7

8.4

7

Minimalist 10% Niacinamide Serum for Acne Control & Oil Balancing with Zinc | Pore Minimizer for Face | Clears Acne Marks & Blemishes for Even Skin Tone | For Women & Men | 1 Fl Oz / 30 ml

8

Good Molecules Niacinamide Serum - 10% Niacinamide to Target Acne, Nourishment, and Skin Tone - Ultra Hydrating Serum and Brightening Skin Care for Face

9

BYOMA Clarifying Serum - Barrier Repair Serum - Clarifying Facial Serum for Acne Prone Skin - Calming Face Serum with Ceramides, Blue Tansy, PHA & Zinc - Balanced & Healthy Skin - 1.01 fl. oz

10

Thayers Double Action Acne Serum with Salicylic Acid, Acne Treatment Face Serum with 2% Salicylic Acid and Niacinamide, Soothing and Non-Stripping Skin Care, 1 Fl Oz

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