10 Best sensitive stomach formulas of 2025

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Best Choice

1

Earth's Best
Earth's Best Organic Sensitivity Infant Formula for Babies 0-12 Months, Reduced Lactose Powder Formula with Iron, Omega-3 DHA, and Omega-6 ARA, 32 Ounce Value Container
Main highlights

Key Features
Reduces fussiness, gas, crying; boosts immunity, brain, eye development. Easy-to-prepare. Supports first year growth.

Ideal Use Cases
Perfect for babies experiencing lactose sensitivity, needing nutritional support from day one to their first birthday.

Customer Reviews
Most praised for significantly reducing digestive issues, leading to happier, more comfortable babies.
Key specs
- nutrition type:Reduced lactose formula
- ingredients:Organic ingredients
- digestibility:Eases fussiness, gas
- age range:First 12 months
- milk source:N/A
9.7

Exceptional

Our Rating

8.7
Flavor

8.4
worth the money

8.2
quality of ingredients
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Value for Money

2

Good Start
Good Start | Dr. Brown’s Gentle Pro, Baby Formula Powder, For Sensitive Tummies, Easy Digestion and Softer Poops, Infant Formula with Probiotics, DHA, Non-GMO, 32 OZ
Main highlights

Key Features
Mimics breastmilk nutrition, easy-to-digest proteins, prebiotics, DHA for brain development. Designed for complete nutrition up to 12 months.

Ideal Use Cases
Perfect for easing infants into bottle feeding, supporting digestive health, and nurturing brain and eye development in the first year.

Customer Reviews Summary
Most praised for its gentleness on baby’s tummy, closely resembling breastmilk, leading to happy, well-fed babies with fewer digestive issues.
9.6

Exceptional

Our Rating

9.9
Comfort

9.3
Flavor

9.1
worth the money
3

Similac
Similac 360 Total Care Sensitive Infant Formula for Fussiness & Gas Due to Lactose Sensitivity, Has 5 HMO Prebiotics, Baby Formula Powder, 20.1-oz Tub
Main highlights

Closest Prebiotic Blend
Similac 360 Total Care Sensitive features 5 HMO prebiotics identical to breast milk, supporting digestion and immune health.

Ideal for Sensitive Tummies
Designed for babies with lactose sensitivity to reduce fussiness and gas.

Praised for Sensitive Stomach Relief
Highly rated by customers for effectively soothing sensitive stomachs in infants.
Key specs
- nutrition type:Gentle nutrition
- ingredients:No artificial growth hormones
- digestibility:For sensitive tummies
- age range:N/A
- milk source:Breast milk identical
9.5

Excellent

Our Rating
4

Similac
Similac Sensitive Infant Formula, for Fussiness & Gas Due to Lactose Sensitivity, Baby Formula Powder, 29.8-oz Value Can
Main highlights

Key Features and Benefits
Specially designed for lactose sensitivity, supports brain and eye development without palm olein oil, and contains no artificial growth hormones.

Ideal Use Cases
Perfect for babies experiencing fussiness and gas due to lactose sensitivity and requiring essential nutrients for development.

Customer Reviews Summary
Most praised for significantly reducing fussiness and gas, with many parents noting improved sleep and comfort for their babies.
Key specs
- nutrition type:Sensitive formula
- ingredients:DHA, lutein, vitamin E
- digestibility:For fussiness and gas
- age range:0 - 1 years
- milk source:N/A
9.4

Excellent

Our Rating
5

Similac

Similac 360 Total Care Sensitive Infant Formula for Fussiness & Gas Due to Lactose Sensitivity, Has 5 HMO Prebiotics, Baby Formula, Ready to Feed, 2-fl-oz Bottle, Pack of 12

36% Off
9.3

Excellent

Our Rating
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6

Enfamil
Enfamil NeuroPro Gentlease Baby Formula, Brain and Immune Support with DHA, Clinically Proven to Reduce Fusiness, Crying, Gas and Spit-up in 24 Hours, Non-GMO, 19.5 Oz
Main highlights

Key Features
Offers all-in-one comfort for fussiness, gas, and spit-up in 24 hours, with DHA for brain development and HuMO6 blend for immune support.

Ideal Use Cases
Perfect for infants up to 12 months experiencing digestive discomfort or parents seeking to support brain growth and immune health.

Customer Reviews
Most praised for its quick relief of digestive issues, making it a trusted choice among parents for infant comfort and well-being.
9.2

Excellent

Our Rating

8.9
worth the money

8.9
Flavor

8.4
Comfort
7

Enfamil
Enfamil Gentlease Baby Formula, Reduces Fussiness, Gas, Crying and Spit-up in 24 hours, DHA & Choline to support Brain development, Value Powder Can, 19.9 Oz
Main highlights

Ease Fussiness and Gas
Enfamil Gentlease has been clinically shown to ease fussiness, crying, gas, and spit-up, making it a comforting choice for your little one.

Ideal for Sensitive Stomachs
Designed for babies up to 12 months with easy-to-digest proteins, vitamins, and minerals, particularly beneficial during formula shortages or for sensitive tummies.

Gentle on Baby's Tummy
Parents frequently praise its ability to reduce gas and fussiness, making it a preferred choice over other formulas that cause discomfort.
9.1

Excellent

Our Rating

9.7
quality of ingredients

9.3
For Gentle skin

8.0
worth the money
8

Similac

Similac Pro-Total Comfort Infant Formula With Iron, 20.1-oz Tub
9.0

Excellent

Our Rating
9

Good Start

Good Start | Dr. Brown's Soothe Pro, Baby Formula Powder, for Sensitive Tummies, Gas, Fussiness and Spit-Up, Infant Formula with Probiotics, DHA, Non-GMO, 12 Ounces
8.9

Very Good

Our Rating
10

Mama Bear
Amazon Brand - Mama Bear Sensitivity Baby Formula Powder, 2'-FL HMO, for Fussiness & Gas when Sensitive to Lactose, Non-GMO, 22.5 oz, 1.4 pound (Pack of 1)

27% Off
Main highlights

Key Features
99% less lactose, supports immune system with 2-FL HMO, enriched with DHA for brain development, and meets FDA standards. Non-GMO.

Ideal Use
Perfect for infants 0-12 months with lactose sensitivity, providing complete nutrition as a breast milk alternative.

Customer Praise
Parents appreciate its ease on sensitive stomachs, comparable to Similac Pro-Sensitive, but at a better value.
Key specs
- nutrition type:Complete nutrition
- ingredients:Reduced lactose, DHA
- digestibility:Reduced lactose, gluten free
- age range:0 - 1 years
- milk source:Milk-based powder
8.8

Very Good

Our Rating

9.9
quality of ingredients

9.1
Flavor

9.1
worth the money

10 Best sensitive stomach formulas of 2025

1

Earth's Best Organic Sensitivity Infant Formula for Babies 0-12 Months, Reduced Lactose Powder Formula with Iron, Omega-3 DHA, and Omega-6 ARA, 32 Ounce Value Container

8.7

8.4

8.2

How do we rank?

How do we rank?

Analyzing top stores

2

Good Start | Dr. Brown’s Gentle Pro, Baby Formula Powder, For Sensitive Tummies, Easy Digestion and Softer Poops, Infant Formula with Probiotics, DHA, Non-GMO, 32 OZ

9.9

9.3

9.1

3

Similac 360 Total Care Sensitive Infant Formula for Fussiness & Gas Due to Lactose Sensitivity, Has 5 HMO Prebiotics, Baby Formula Powder, 20.1-oz Tub

4

Similac Sensitive Infant Formula, for Fussiness & Gas Due to Lactose Sensitivity, Baby Formula Powder, 29.8-oz Value Can

5

Similac 360 Total Care Sensitive Infant Formula for Fussiness & Gas Due to Lactose Sensitivity, Has 5 HMO Prebiotics, Baby Formula, Ready to Feed, 2-fl-oz Bottle, Pack of 12

6

Enfamil NeuroPro Gentlease Baby Formula, Brain and Immune Support with DHA, Clinically Proven to Reduce Fusiness, Crying, Gas and Spit-up in 24 Hours, Non-GMO, 19.5 Oz

8.9

8.9

8.4

7

Enfamil Gentlease Baby Formula, Reduces Fussiness, Gas, Crying and Spit-up in 24 hours, DHA & Choline to support Brain development, Value Powder Can, 19.9 Oz

9.7

9.3

8.0

8

Similac Pro-Total Comfort Infant Formula With Iron, 20.1-oz Tub

9

Good Start | Dr. Brown's Soothe Pro, Baby Formula Powder, for Sensitive Tummies, Gas, Fussiness and Spit-Up, Infant Formula with Probiotics, DHA, Non-GMO, 12 Ounces

10

Amazon Brand - Mama Bear Sensitivity Baby Formula Powder, 2'-FL HMO, for Fussiness & Gas when Sensitive to Lactose, Non-GMO, 22.5 oz, 1.4 pound (Pack of 1)

9.9

9.1

9.1

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