November 3, 2025

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10 Best rls supplements of 2025

Save up to 47% off

Best Choice

1

Approved Science

Approved Science Restlex - 420 mg Magnesium Glycinate Blend, L-theanine 200 mg - 60 Capsules
9.6

Exceptional

Our Rating
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Based on millions of stores and reviews

Shoppers influence our rankings
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Value for Money

2

Double Wood Supplements
Magnesium L Threonate, Magtein, Sleep and Cognitive Support – High Absorption – Most Bioavailable Form of Magnesium – 2,000 mg – 120 Capsules

14% Off
Main highlights

Supports Brain Magnesium Levels
Magtein Magnesium L-Threonate is the only form clinically proven to boost brain magnesium levels.

Ideal for Sleep and Cognitive Health
Perfect for those seeking enhanced sleep quality and cognitive support.

Praised for Sleep Improvement
Customers appreciate its effectiveness in improving sleep without causing a laxative effect.
9.5

Excellent

Our Rating

9.7
simple to consume

9.5
Absorbency

9.3
quality of sleep
3

Hyland's
Hyland's Restful Legs PM, Nighttime Formula, Calms Agitated Legs so You Can Sleep, 50 Quick Dissolving Tablets

32% Off
Main highlights

Natural Relief for Restless Legs
Provides relief from itching, crawling, and tingling sensations.

Ideal for Nighttime Use
Perfect for those experiencing sleeplessness due to restless legs.

Quick-Acting Formula
Customers praise the fast relief, often within minutes.
9.3

Excellent

Our Rating

9.5
Simple to use

8.4
Flavor

8.2
worth the money
4

Hyland's
Hyland's Restful Legs Tablets, Natural Itching, Crawling, Tingling and Leg Jerk Relief, Quick Dissolving Tablets, 50 Count

26% Off
Main highlights

Natural Relief for Restless Legs
Provides relief from itching, tingling, and the urge to move legs.

Ideal for Bedtime Use
Perfect for those experiencing restless legs syndrome before sleep.

Highly Effective According to Users
Praised for quick relief and aiding in sleep improvement.
Key specs
- features:Quick-dissolving tablets
- components:50 tablets
- usage:Relief of agitated legs
- origin:USA
- dimensions:4 x 1.38 x 1.38 inches
9.2

Excellent

Our Rating

9.7
Simple to use

8.7
worth the money

8.7
Flavor
5

Nature's Bounty
Nature's Bounty Magnesium 500 mg Tablets, High Potency Magnesium Supplement for Bone & Muscle Health, Whole Body Support, 200 Count (Pack of 1)

47% Off
Main highlights

Bone and Muscle Health Support
Magnesium plays an essential role in bone health and muscle function.

Daily Energy and Metabolism Boost
Ideal for individuals seeking improved energy and muscle function.

Easy to Swallow and Effective
Users praise the tablet's ease of swallowing and effectiveness.
9.0

Excellent

Our Rating

9.7
worth the money

9.3
Absorbency

9.1
simple to consume
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6

Hyland's
Hyland's Restful Legs PM, Nighttime Formula, Calms Agitated Legs so You Can Sleep, 50 Quick Dissolving Tablets (Pack of 2)
Main highlights

Quick Dissolving Tablets
Hylands Restful Legs PM offers fast relief with quick-dissolving tablets, ensuring convenience and ease of use for nighttime discomfort.

Nighttime Restlessness Relief
Ideal for those experiencing restless legs at night, providing soothing comfort and aiding in restful sleep.

Highly Effective Non-Prescription
Praised for its effectiveness, often compared favorably to prescription alternatives by users.
8.9

Very Good

Our Rating

9.3
Flavor

9.1
worth the money
7

Calm Legs
Calm Legs Natural for Natural Itching, Crawling, Tingling and Agitated Leg with Iron, Magnesium, and Valerian Root (60 Tablets)…
Main highlights

Support Leg Muscle Relaxation
Natural ingredients like magnesium and valerian root promote leg muscle relaxation and improve sleep quality.

Ideal for Restless Legs
Perfect for those experiencing restless legs, itching, tingling, and crawling sensations.

Best Effectiveness Among Competitors
Customers consistently praise its effectiveness compared to other brands.
Key specs
- Usage:Supports leg muscle relaxation
- Ingredients:Iron, magnesium, valerian root
- Melatonin:N/A
- Gluten-Free:N/A
- Form:N/A
8.7

Very Good

Our Rating

9.7
quality of sleep

9.5
quality of ingredients

9.1
pain management
8

BIOptimizers
BIOptimizers Magnesium Breakthrough Complex Supplement with 7 Forms of Mg: Glycinate, Malate, Citrate, and More - Natural Support for Sleep and Cognitive Function - 30 Capsules- Calming Vitamins
Main highlights

Comprehensive Magnesium Formula
Contains 7 forms of magnesium to support bodily functions and counter magnesium deficiency.

Optimal for Sleep and Brain Health
Ideal for improving sleep quality and supporting cognitive function through natural ingredients.

Highly Praised for Easy Absorption
Customers appreciate its fast absorption and minimal digestive discomfort.
8.5

Good

Our Rating

9.9
Flavor

9.5
simple to consume

9.3
Absorbency
9

MagniLife
MagniLife Relaxing Legs, Restless Legs, Natural Sleep Aid and Pain Reliever, Calms Jerks, Restlessness, and Discomfort - 125 Quick Dissolve Tablets
Main highlights

Key Features and Benefits
Quick-dissolve tablets relieve leg discomfort, aiding sleep by stopping unpleasant sensations and promoting relaxation.

Ideal Use Cases
Best for individuals experiencing restless legs syndrome, nighttime leg discomfort, or difficulty sleeping due to leg sensations.

Customer Reviews Highlight
Most praised for its fast-acting relief, significantly improving sleep quality for users with restless legs.
Key specs
- dosage form:Tablets
- application method:Oral
- product type:Sleeping Aid
- skin type:N/A
- number of patches:N/A
8.4

Good

Our Rating

9.7
Simple to use

8.7
Aroma

8.4
worth the money
10

Natural Rhythm
Natural Rhythm Triple Calm Magnesium 150 mg - 120 Capsules – Magnesium Complex Compound Supplement with Magnesium Glycinate, Malate, and Taurate. Calming Blend for Promoting Rest and Relaxation.
Main highlights

Promotes Tranquility and Well-Being
Incorporates magnesium taurate, glycinate, and malate for rest and relaxation.

Ideal for Restoring Natural Rhythm
Use as a supplement for magnesium deficiency or enhancing life rhythm.

Gentle and Effective Formula
Highly praised for non-laxative, easy-to-swallow capsules.
8.2

Good

Our Rating

9.7
simple to consume

9.3
Absorbency

9.3
Flavor

10 Best rls supplements of 2025

1

Approved Science Restlex - 420 mg Magnesium Glycinate Blend, L-theanine 200 mg - 60 Capsules

How do we rank?

How do we rank?

Analyzing top stores

2

Magnesium L Threonate, Magtein, Sleep and Cognitive Support – High Absorption – Most Bioavailable Form of Magnesium – 2,000 mg – 120 Capsules

9.7

9.5

9.3

3

Hyland's Restful Legs PM, Nighttime Formula, Calms Agitated Legs so You Can Sleep, 50 Quick Dissolving Tablets

9.5

8.4

8.2

4

Hyland's Restful Legs Tablets, Natural Itching, Crawling, Tingling and Leg Jerk Relief, Quick Dissolving Tablets, 50 Count

9.7

8.7

8.7

5

Nature's Bounty Magnesium 500 mg Tablets, High Potency Magnesium Supplement for Bone & Muscle Health, Whole Body Support, 200 Count (Pack of 1)

9.7

9.3

9.1

6

Hyland's Restful Legs PM, Nighttime Formula, Calms Agitated Legs so You Can Sleep, 50 Quick Dissolving Tablets (Pack of 2)

9.3

9.1

7

Calm Legs Natural for Natural Itching, Crawling, Tingling and Agitated Leg with Iron, Magnesium, and Valerian Root (60 Tablets)…

9.7

9.5

9.1

8

BIOptimizers Magnesium Breakthrough Complex Supplement with 7 Forms of Mg: Glycinate, Malate, Citrate, and More - Natural Support for Sleep and Cognitive Function - 30 Capsules- Calming Vitamins

9.9

9.5

9.3

9

MagniLife Relaxing Legs, Restless Legs, Natural Sleep Aid and Pain Reliever, Calms Jerks, Restlessness, and Discomfort - 125 Quick Dissolve Tablets

9.7

8.7

8.4

10

Natural Rhythm Triple Calm Magnesium 150 mg - 120 Capsules – Magnesium Complex Compound Supplement with Magnesium Glycinate, Malate, and Taurate. Calming Blend for Promoting Rest and Relaxation.

9.7

9.3

9.3

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