October 19, 2025

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10 Best refrigerated probiotics of 2025

Save up to 19% off

Best Choice

1

Visbiome
Visbiome® GI Care - High Potency Probiotic - 112.5 Billion CFU Live Probiotics, Original De Simone Formulation, Made in USA, 60 Capsules.
Main highlights

Powerful Probiotic Blend
Contains 8 clinically-tested strains with 112.5 billion CFU per capsule, designed for optimal gut health in both men and women.

Ideal for Gut Health Maintenance
Best for individuals needing potent probiotics for gut health, supported by over 100 clinical trials and recommended by doctors.

Highly Praised Cold Shipping
Customers appreciate the cold shipping with ice packs and temperature monitoring, ensuring the product arrives in optimal condition.
Key specs
- CFU:112.5 billion
- Form:Capsule
- Strains:8 clinically-tested
- Gluten Free:Yes
- Features:Low-FODMAP, Non-GMO
9.8

Exceptional

Our Rating

9.9
Packaging materials

9.9
Temperature control

9.7
quality of ingredients
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Garden of Life
Garden of Life Probiotics for Women and Men Raw Probiotics Ultimate Care 100 Billion CFU Probiotic Supplement, Daily Probiotic for Adults with Digestive Enzymes, 30 Capsules

11% Off
Main highlights

Key Features and Benefits
100 Billion CFU with 34 probiotic strains, Clinically Studied species, added vitamins, minerals, and digestive enzymes for enhanced gut health.

Ideal Use Cases
Perfect for restoring gut balance, supporting healthy digestion, nutrient assimilation, and boosting the immune system in both men and women.

Customer Reviews Summary
Highly praised for its effectiveness in improving digestive health and maintaining gut flora balance, with noticeable results.
Key specs
- CFU:100 Billion
- Form:Capsule
- Strains:34 Probiotic Strains
- Gluten Free:Yes
- Features:Non-GMO, Digestive Enzymes
9.7

Exceptional

Our Rating

9.5
simple to consume

9.1
Flavor

8.2
worth the money
3

Florajen
Florajen3 Digestion High Potency Refrigerated Probiotics | Restores Balance in Digestive System | for Antibiotic Side Effects | 60 Capsules

11% Off
Main highlights

Key Features and Benefits
Allergen-free, non-GMO, and kosher, promoting digestive health with a multiculture blend in GMP-certified facilities.

Ideal Use Cases
Ideal for those with dietary restrictions, and to alleviate digestive upset, especially beneficial following antibiotic use.

Customer Reviews Summary
Most praised for its effectiveness in improving gut health and its ability to alleviate digestive discomfort without causing allergies.
Key specs
- Usage:Digestive health support
- Formulation:Capsules
- Ingredient Type:Lactobacillus acidophilus, Bifidobacterium
- Effect:Restore digestive balance
- Support Type:Digestive
9.6

Exceptional

Our Rating

9.3
simple to consume

8.2
Flavor

8.0
worth the money
4

Physician's CHOICE
Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 60ct

10% Off
Main highlights

Supports Digestive Health & Gut Balance
The probiotic contains 60 billion CFU and 10 strains to support digestive health and a balanced gut microbiome.

Perfect for Gut Health Challenges
Ideal for managing occasional constipation, diarrhea, gas, and bloating, enhancing gut health.

Improved Digestion & Reduced Bloating
Customers praise its effectiveness in improving digestion and reducing bloating.
Key specs
- Type:General Probiotic
- Usage:Supports digestive health
- Strains:10 diverse strains
- Formulation:Acid-resistant capsules
- Ingredients:Probiotics and prebiotics
9.5

Excellent

Our Rating

9.7
simple to consume

9.5
worth the money

9.5
quality of ingredients
5

Garden of Life
Garden of Life Raw Probiotics for Women and Men with Digestive Enzymes, 100 Billion CFU, Clinically Studied Strains, Shelf Stable, 30 Capsules
Main highlights

High Potency Probiotic Formula
Contains 100 Billion CFU and 34 strains for optimal gut health.

Convenient for Travel
Shelf-stable, no need for refrigeration, ideal for busy lifestyles.

Clinically Studied Strains
Praised for its effective strains supporting digestive health.
Key specs
- CFU:100 Billion
- Form:Capsule
- Strains:34 Probiotic Strains
- Gluten Free:Yes
- Features:Non-GMO, Enzymes, Vitamins
9.3

Excellent

Our Rating

9.5
simple to consume

9.1
Flavor

8.2
worth the money
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6

Physician's CHOICE
Physician's Choice Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 30ct

18% Off
Main highlights

Digestive and Gut Support
Max Strength General Purpose Probiotic with 60B CFU supports digestive and gut health for a balanced microbiome.

Best for Digestive Issues
Ideal for occasional constipation, diarrhea, gas, and bloating relief in both women and men.

Customer Praised Effectiveness
Users report significant improvements in digestion and energy levels after consistent use.
9.2

Excellent

Our Rating

9.7
simple to consume

9.5
worth the money

9.5
quality of ingredients
7

Florajen

Florajen Digestion Probiotics, Gut Health Supplement with Constipation and Bloating Relief for Adults, 30 Count (Refrigerated)
8.9

Very Good

Our Rating
8

Garden of Life
Garden of Life Once Daily Dr. Formulated Probiotics for Women 50 Billion CFU 16 Probiotic Strains with Organic Prebiotics for Digestive, Vaginal & Immune Health, Dairy Free, Shelf Stable 30 Capsules

10% Off
Main highlights

50 Billion CFU for Digestive and Immune Support
Formulated with 50 Billion CFU and 16 probiotics for optimal digestive and immune health.

Perfect for Women's Health Needs
Designed to support women's digestive, immune, and reproductive health, including maintaining balanced pH levels.

Praised for Gut Health Benefits
Customers frequently commend its impact on gut health and overall well-being.
8.8

Very Good

Our Rating

9.1
simple to consume

8.9
worth the money

8.9
quality of ingredients
9

Flora
Flora - Super 8 Hi-Potency Probiotic - Daily Probiotic for Gut & Digestive Health - 42 Billion CFU - Contains Lactobacillus & Bifidobacterium Strains - Keep Chilled - 60 Capsules
Main highlights

Key Features
High potency with 42 Billion CFU, 8 active strains, survives stomach acid, supports yeast balance, digestive and immune health. Gluten-free, vegetarian.

Ideal Use Cases
Perfect for those looking to maintain vaginal health, proper yeast balance, and enhance digestive function amidst modern dietary and lifestyle challenges.

Customer Reviews
Most praised for its effectiveness in improving digestive health and maintaining yeast balance, leading to noticeable improvements in overall well-being.
8.5

Good

Our Rating
10

Garden of Life
Garden of Life Raw Probiotics for Women - 85 Billion CFU Probiotic for Vaginal Probiotics with Vitamins, Minerals, Enzymes - 90 Capsules, Womens Probiotic Supplement for Digestive and Immune Health

19% Off
Main highlights

Probiotic Potency and Diversity
85 Billion CFU from 32 diverse strains, including Lactobacillus and Bifidobacteria, plus vitamins and digestive enzymes for comprehensive digestive and vaginal health support.

Ideal for Post-Antibiotic Recovery
Perfect for women recovering from antibiotics, dealing with digestive issues, or seeking overall gut and vaginal health improvement.

Effective for Digestive and Vaginal Health
Praised for significantly improving digestion, reducing bloating, and enhancing vaginal health, making it a highly recommended choice for women.
Key specs
- CFU:85 Billion
- Form:Probiotic supplement
- Strains:32 diverse strains
- Gluten Free:Yes
- Features:Non-GMO, NSF Gluten-Free
8.4

Good

Our Rating

9.9
quality of ingredients

9.1
simple to consume

9.1
Flavor

10 Best refrigerated probiotics of 2025

1

Visbiome® GI Care - High Potency Probiotic - 112.5 Billion CFU Live Probiotics, Original De Simone Formulation, Made in USA, 60 Capsules.

9.9

9.9

9.7

How do we rank?

How do we rank?

Analyzing top stores

2

Garden of Life Probiotics for Women and Men Raw Probiotics Ultimate Care 100 Billion CFU Probiotic Supplement, Daily Probiotic for Adults with Digestive Enzymes, 30 Capsules

9.5

9.1

8.2

3

Florajen3 Digestion High Potency Refrigerated Probiotics | Restores Balance in Digestive System | for Antibiotic Side Effects | 60 Capsules

9.3

8.2

8.0

4

Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 60ct

9.7

9.5

9.5

5

Garden of Life Raw Probiotics for Women and Men with Digestive Enzymes, 100 Billion CFU, Clinically Studied Strains, Shelf Stable, 30 Capsules

9.5

9.1

8.2

6

Physician's Choice Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 30ct

9.7

9.5

9.5

7

Florajen Digestion Probiotics, Gut Health Supplement with Constipation and Bloating Relief for Adults, 30 Count (Refrigerated)

8

Garden of Life Once Daily Dr. Formulated Probiotics for Women 50 Billion CFU 16 Probiotic Strains with Organic Prebiotics for Digestive, Vaginal & Immune Health, Dairy Free, Shelf Stable 30 Capsules

9.1

8.9

8.9

9

Flora - Super 8 Hi-Potency Probiotic - Daily Probiotic for Gut & Digestive Health - 42 Billion CFU - Contains Lactobacillus & Bifidobacterium Strains - Keep Chilled - 60 Capsules

10

Garden of Life Raw Probiotics for Women - 85 Billion CFU Probiotic for Vaginal Probiotics with Vitamins, Minerals, Enzymes - 90 Capsules, Womens Probiotic Supplement for Digestive and Immune Health

9.9

9.1

9.1

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