10 Best rash creams of 2025

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Best Choice

1

Calmoseptine
Calmoseptine Ointment by Calmoseptine
Main highlights

Fast and Effective Relief
Calmoseptine Ointment provides quick relief from diaper rash, often clearing it up within hours.

Versatile Use Cases
Ideal for diaper rash, post-surgery skin issues, and general skin protection.

Highly Praised Thickness
Customers appreciate its thick consistency for effective protection and healing.
9.8

Exceptional

Our Rating

9.9
Long life

9.5
worth the money

9.1
Easy to use
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Value for Money

2

LMNOOP
LMNOOP Eczema Cream, Maximum Strength Treatment Ointment for Rash, Psoriasis, Dermatitis, Urticaria, Jock Itch, Fungal Infection, Anti-Itch, Relief for Sensitive, Irritated Skin 1.76oz
Main highlights

Healing and Moisturizing Benefits
LMNOOP Eczema Therapy Cream heals eczema, soothes irritation, and moisturizes skin.

Versatile Use for Skin Conditions
Ideal for eczema, psoriasis, dermatitis, and fungal infections.

Quick and Effective Relief
Customers praise its fast action in relieving itchy and inflamed skin.
9.7

Exceptional

Our Rating
3

Cortizone-10
Cortizone-10 Maximum Strength Intensive Healing Itch Relief Lotion for Eczema, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Minor Skin Irritations, Rashes and Inflammation Due to Eczema, 3.5 oz
Main highlights

Maximum Strength Itch Relief
Contains 1% hydrocortisone for fast relief of itch and inflammation.

Ideal for Eczema and Dry Skin
Clinically proven to moisturize for 24 hours, perfect for eczema.

Instant Itch Reduction
Customers praise its immediate effectiveness in reducing itchiness.
9.6

Exceptional

Our Rating

9.7
Moisturizing

9.5
worth the money

9.5
Fashion
4

Amazon Basic Care
Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, Itch Relief For Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Pack of 1)
Main highlights

Maximum Strength Relief
Contains hydrocortisone 1% for fast, effective itch relief.

Versatile Use Cases
Ideal for bug bites, eczema, psoriasis, and poison ivy.

Highly Praised Value
Works as well as name brands at a lower price.
Key specs
- form:Cream
- size:1.45 ounces
- moisturizers:Antioxidants, chamomile, vitamins
- cream type:Anti-itch cream
- active ingredient:Hydrocortisone 1 percent
9.4

Excellent

Our Rating

9.9
quality of ingredients

9.7
Moisturizing

9.1
Aroma
5

A+D

A+D Medicated Rash Ointment 1.5 oz– Relieves Rash & Skin Irritated Skin from Poison Ivy, Eczema, Beard Rash, Bikini Rash, Dry Skin, Chapped Skin, bug bites. Made with Colloidal Oatmeal
9.3

Excellent

Our Rating
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6

Cortizone-10
Cortizone-10 Maximum Strength Intensive Healing Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz
Main highlights

Maximum Strength Itch Relief
Cortizone-10 provides fast relief from itch with maximum-strength hydrocortisone and nourishing moisturizers.

Ideal for Minor Skin Irritations
Perfect for relieving itch from dry, chafed, and chapped skin.

Instant Relief and No Grease
Highly praised for its quick action and non-greasy feel.
Key specs
- form:Cream
- size:2-oz. tube
- moisturizers:Seven moisturizers
- cream type:Anti-Itch Cream
- active ingredient:1 hydrocortisone
9.2

Excellent

Our Rating
7

Desitin
Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide, Hypoallergenic No Added Parabens & Dyes, Protects & Relieves Baby’s Skin for Up to 12 Hours, Prevents Diaper Rash, 4.8 oz Tube

32% Off
Main highlights

Maximum Strength Relief
Desitin's 40% zinc oxide formula provides up to 12-hour protection and healing for diaper rash.

Ideal for Sensitive Skin
Hypoallergenic and free of parabens, phthalates, dyes, and soap, perfect for daily use on baby's sensitive skin.

Highly Recommended by Users
Praised for its effectiveness, forming a protective barrier and soothing chafed skin quickly.
Key specs
- Size:4.8-ounce tube
- Formulation:Paraben-free, dye-free
- Ingredients:40% zinc oxide
- Hypoallergenic:Yes
- Features:5-in-1 action
9.1

Excellent

Our Rating

9.7
Simple to use

9.5
Easy to use

9.5
Comfort
8

Cortizone 10
Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz
Main highlights

Maximum Strength Relief
Contains 1% hydrocortisone for fast, effective itch relief.

Ideal for Itch and Irritation
Perfect for eczema, psoriasis, insect bites, and rashes.

Praised for Quick Absorption
Non-greasy formula absorbs quickly, leaving no residue.
Key specs
- form:Cream
- size:2 oz.
- moisturizers:Aloe
- cream type:Anti-Itch Cream
- active ingredient:1% hydrocortisone
8.9

Very Good

Our Rating
9

Boudreaux's Butt Paste
Boudreaux's Butt Paste Maximum Strength Diaper Rash Cream, Ointment for Baby, 4 oz Tube

26% Off
Main highlights

Fast Relief and Protection
Clinically tested formula provides fast relief and protects irritated skin instantly.

Ideal for Sensitive Skin
Perfect for daily prevention and treatment of moderate diaper rash.

Highly Effective and Long-lasting
Praised for staying on long and soothing sensitive skin.
8.8

Very Good

Our Rating

9.7
Simple to use

9.5
Easy to use

9.1
For Gentle skin
10

Benadryl
Benadryl Extra Strength Anti Itch Relief Gel, 2% Diphenhydramine HCl, Relief from Insect Bites, Sunburn & More, Great for Camping Essentials, 3.5 fl oz

26% Off
Main highlights

Fast-Acting Cooling Relief
Benadryl Extra Strength Gel provides quick relief from itching and pain caused by insect bites, sunburn, and minor skin irritations.

Outdoor Activity Essential
Ideal for camping, hiking, and outdoor events, offering relief for ages 2 and up.

Instant Itch Control
Customers praise its immediate itch relief and cooling sensation, making it a must-have for skin irritations.
Key specs
- Item Form:Gel
- Recommended Use:Insect bites, sunburn
- Dimensions:1.47 x 2.43 x 6.35 inches
- Special Feature:Anti-itch relief
- Reusability:N/A
8.5

Good

Our Rating

8.7
Simple to use

8.4
worth the money

8.4
For traveling

10 Best rash creams of 2025

1

Calmoseptine Ointment by Calmoseptine

9.9

9.5

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

LMNOOP Eczema Cream, Maximum Strength Treatment Ointment for Rash, Psoriasis, Dermatitis, Urticaria, Jock Itch, Fungal Infection, Anti-Itch, Relief for Sensitive, Irritated Skin 1.76oz

3

Cortizone-10 Maximum Strength Intensive Healing Itch Relief Lotion for Eczema, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Minor Skin Irritations, Rashes and Inflammation Due to Eczema, 3.5 oz

9.7

9.5

9.5

4

Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, Itch Relief For Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Pack of 1)

9.9

9.7

9.1

5

A+D Medicated Rash Ointment 1.5 oz– Relieves Rash & Skin Irritated Skin from Poison Ivy, Eczema, Beard Rash, Bikini Rash, Dry Skin, Chapped Skin, bug bites. Made with Colloidal Oatmeal

6

Cortizone-10 Maximum Strength Intensive Healing Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

7

Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide, Hypoallergenic No Added Parabens & Dyes, Protects & Relieves Baby’s Skin for Up to 12 Hours, Prevents Diaper Rash, 4.8 oz Tube

9.7

9.5

9.5

8

Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

9

Boudreaux's Butt Paste Maximum Strength Diaper Rash Cream, Ointment for Baby, 4 oz Tube

9.7

9.5

9.1

10

Benadryl Extra Strength Anti Itch Relief Gel, 2% Diphenhydramine HCl, Relief from Insect Bites, Sunburn & More, Great for Camping Essentials, 3.5 fl oz

8.7

8.4

8.4

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