10 Best preservative free moisturizing eye drops of 2025

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Systane
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)

31% Off
Main highlights

Fast Acting Hydration
Nano droplets provide quick and effective moisture for sensitive eyes.

Ideal for Post-Lasik
Recommended for use before and after Lasik surgery for optimal recovery.

Improved Bottle Design
New squeeze bottle retains shape and reduces waste, praised by users.
9.9

Exceptional

Our Rating

9.1
Long life

9.1
Moisturizing

8.2
worth the money
How do we rank?

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Based on millions of stores and reviews

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Value for Money

2

Refresh
Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free,Value Size, 0.01 Fl Oz Single-Use Containers, 70 Count

33% Off
Main highlights

Preservative-Free Comfort
Original strength, preservative-free formula ideal for sensitive eyes.

Post-Surgery Relief
Effective for dryness relief after LASIK or cataract surgery.

Single-Use Convenience
Praised for sterile, single-use vials reducing contamination risk.
Key specs
- Preservative Free:Yes
- Use Case:After LASIK or surgeries
- Relief Duration:Instantly moisturizes
- Eye Comfort:Great for sensitive eyes
- Moisturizing Formula:Preservative-free formula
9.7

Exceptional

Our Rating

9.9
Simple to use

9.3
worth the money
3

Systane
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)

15% Off
Main highlights

Fast Hydration and Long-Lasting Relief
Provides quick hydration and sustained relief for dry eyes.

Ideal for Contact Lens Wearers
Safe for use with all contact lenses, perfect for daily wear.

User-Friendly Bottle Design
Customers appreciate the easy-to-use bottle, despite some dispensing issues.
Key specs
- Formula:Contains hyaluronate
- Usage:Safe with contact lenses
- Preservatives:Preservative free
- Hydration:Advanced hydration
- Content:1.45 ounces
9.6

Exceptional

Our Rating

9.3
Moisturizing

8.7
worth the money

8.0
Simple to use
4

Refresh
Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count
Main highlights

Preservative-Free Formula
Original strength, preservative-free formula that mimics natural tears.

Ideal for Post-Surgery and Dry Eyes
Recommended for use after LASIK and for relieving mild dryness.

Highly Praised Convenience
Single-use vials praised for preventing contamination and ensuring hygiene.
Key specs
- Preservative Free:Yes
- Use Case:After LASIK or surgeries
- Relief Duration:Instantly moisturizes and lubricates
- Eye Comfort:Great for sensitive eyes
- Moisturizing Formula:Original strength, preservative-free
9.4

Excellent

Our Rating

9.5
Simple to use

9.5
Moisturizing

9.3
Comfort
5

TheraTears
TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials

15% Off
Main highlights

Immediate Long-Lasting Relief
TheraTears provides immediate, long-lasting relief from dry eye symptoms with its unique formula.

Ideal After LASIK
Perfect for post-LASIK care, offering gentle hydration and soothing relief.

Praised Reusability
Customers love the reusability of vials, minimizing waste and maximizing value.
Key specs
- Formula:Lubricant eye drops
- Usage:Immediate relief
- Preservatives:Preservative free
- Hydration:Silky hydration
- Content:30 vials
9.2

Excellent

Our Rating

9.9
Simple to use

9.1
Moisturizing

8.9
Comfort
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6

iVIZIA
iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz Bottle

28% Off
Main highlights

Preservative-Free Moisturizing Relief
iVIZIA eye drops offer preservative-free relief, utilizing hydrating polymers and hyaluronic acid for long-lasting moisture.

Ideal for Dry Eye Sufferers
Perfect for individuals with dry eyes, especially contact lens users seeking comfort and hydration.

Highly Praised for Nighttime Use
Customers appreciate its effectiveness in reducing nighttime dryness, allowing restful sleep with fewer interruptions.
Key specs
- Formula:Hydrating polymers, Hyaluronic Acid
- Usage:Contact lens friendly
- Preservatives:Preservative-Free
- Hydration:Moisturizing, holds 1000x moisture
- Content:0.33 fl oz
9.1

Excellent

Our Rating

9.9
Moisturizing

8.7
Simple to use

8.0
dispense easily
7

BLINK

Blink Boost Preservative-Free Lubricating Eye Drops, Eye Care Drops for Dry Eyes, Instant Moisture for Dry Irritated Eyes & Comfort Throughout the Day, Contact Lens Friendly, 10 mL
9.0

Excellent

Our Rating
8

Refresh

Refresh Tears PF Preservative-Free Artificial Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)
8.7

Very Good

Our Rating
9

Biotrue
Biotrue Hydration Boost, Preservative-Free Eye Drops for Dry Eyes, Instantly Moisturizes, Rehydrates, Contact Lens Friendly, Refresh & Relieve Eye Irritation, 0.33 FL Oz (Pack of 2)
Main highlights

Key Features and Benefits
Features HA Hyaluronan, antioxidants, and electrolytes for instant moisture. Preservative-free and pH balanced, suitable for contact lens wearers.

Ideal Use Cases
Perfect for relieving dry, irritated eyes caused by extensive screen use, environmental factors, and contact lens wear.

Customer Reviews Highlight
Most praised for providing immediate relief and comfort to dry eyes, with users appreciating its contact lens compatibility.
8.6

Very Good

Our Rating

9.9
Comfort

9.3
worth the money

9.3
Moisturizing
10

Systane
Systane Ultra Multi-Dose Preservative-Free Eye Drops Twin Pack (2x10ml)

29% Off
Main highlights

Preservative-Free Hydration
Fast-acting hydration with a preservative-free formula for sensitive eyes, providing lasting dry eye relief.

Ideal for Screen Users
Perfect for users experiencing dry eyes from prolonged screen time or contact lens wear.

Highly Effective Relief
Customers praise its effectiveness in soothing dry and irritated eyes despite the bottle design.
Key specs
- Preservative Free:Preservative-Free
- Use Case:dry eye symptom relief
- Relief Duration:lasting dry eye relief
- Eye Comfort:for sensitive eyes
- Moisturizing Formula:Moisture rich formula
8.5

Good

Our Rating

10 Best preservative free moisturizing eye drops of 2025

1

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)

9.1

9.1

8.2

How do we rank?

How do we rank?

Analyzing top stores

2

Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free,Value Size, 0.01 Fl Oz Single-Use Containers, 70 Count

9.9

9.3

3

Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)

9.3

8.7

8.0

4

Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count

9.5

9.5

9.3

5

TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials

9.9

9.1

8.9

6

iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz Bottle

9.9

8.7

8.0

7

Blink Boost Preservative-Free Lubricating Eye Drops, Eye Care Drops for Dry Eyes, Instant Moisture for Dry Irritated Eyes & Comfort Throughout the Day, Contact Lens Friendly, 10 mL

8

Refresh Tears PF Preservative-Free Artificial Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)

9

Biotrue Hydration Boost, Preservative-Free Eye Drops for Dry Eyes, Instantly Moisturizes, Rehydrates, Contact Lens Friendly, Refresh & Relieve Eye Irritation, 0.33 FL Oz (Pack of 2)

9.9

9.3

9.3

10

Systane Ultra Multi-Dose Preservative-Free Eye Drops Twin Pack (2x10ml)

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