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10 Best pimple spot treatments of 2026

Save up to 28% off
  • Best Choice

    1

    Mighty Patch Hero Cosmetics Original Nighttime Acne Pimple Patches, 36 Ct
    Mighty Patch
    9.9
    Exceptional

    Mighty Patch Hero Cosmetics Original Nighttime Acne Pimple Patches, 36 Ct

    • is discontinued by manufacturer:No
    • product dimensions:5.5 x 3.25 x 0.75 inches; 0.8 ounces
    • upc:864475000404
    • asin:B074PVTPBW
    • item model number:BP29693105
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  • Value for Money

    2

    Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel, 1 oz
    Neutrogena
    9.8
    Exceptional

    Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel, 1 oz

    28% Off
    • is discontinued by manufacturer:No
    • upc:070501024614
    • asin:B00NR1YVYU
    • item model number:70501024614
    • manufacturer:Kenvue

  • 3

    Neutrogena On-The-Spot Acne Spot Treatment Cream, 0.75 oz
    Neutrogena
    9.5
    Excellent

    Neutrogena On-The-Spot Acne Spot Treatment Cream, 0.75 oz

    17% Off
    • is discontinued by manufacturer:Yes
    • product dimensions:1.45 x 3.95 x 3.95 inches; 0.75 ounces
    • upc:070501017906
    • asin:B00UOLIOC6
    • item model number:2620649002

  • 4

    AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1
    AcneFree
    9.3
    Excellent

    AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1

    • is discontinued by manufacturer:No
    • product dimensions:4.57 x 1.45 x 3.74 inches; 1 ounces
    • upc:850004234785
    • asin:B0014VTOAQ
    • department:unisex-adult

  • 5

    Differin Acne Spot Treatment, Max Strength, 10% Benzoyl Peroxide, 1oz
    Differin
    9.2
    Excellent

    Differin Acne Spot Treatment, Max Strength, 10% Benzoyl Peroxide, 1oz

    16% Off
    • is discontinued by manufacturer:N/A
    • product dimensions:N/A
    • upc:302994611003
    • asin:B0D355W5F2
    • item model number:0299.053078
  • See Today’s Deals & Prices

  • 6

    The Ordinary Sulfur 10% Powder-to-Cream Acne Spot Treatment Concentrate, Reduces Pimple Size and Zit Redness, 0.18 Oz
    The Ordinary
    9.0
    Excellent

    The Ordinary Sulfur 10% Powder-to-Cream Acne Spot Treatment Concentrate, Reduces Pimple Size and Zit Redness, 0.18 Oz

  • 7

    Dr.Leo 1.8% Salicylic Acid Acne Spot Treatment Drying Lotion, 0.34oz
    Dr.Leo
    8.8
    Very Good

    Dr.Leo 1.8% Salicylic Acid Acne Spot Treatment Drying Lotion, 0.34oz

    17% Off Limited Time Deal

  • 8

    La Roche-Posay Effaclar Salicylic Acid Acne Treatment for Face 1.35 oz
    La Roche-Posay
    8.7
    Very Good

    La Roche-Posay Effaclar Salicylic Acid Acne Treatment for Face 1.35 oz

    25% Off

  • 9

    Murad Rapid Relief Acne Spot Treatment – Acne Control Max Strength 2% Salicylic Acid Invisible Gel Spot Solution for Fast Acne Relief - Reduces Blemish Size and Redness Within 4 Hours, 0.5 Oz
    Murad
    8.6
    Very Good

    Murad Rapid Relief Acne Spot Treatment – Acne Control Max Strength 2% Salicylic Acid Invisible Gel Spot Solution for Fast Acne Relief - Reduces Blemish Size and Redness Within 4 Hours, 0.5 Oz

    • upc:767332108032
    • is discontinued by manufacturer:No
    • asin:B06XDTLQ1Y
    • product dimensions:9.8 x 7.9 x 3.9 inches 0.01 ounces
    • item model number:10803MU

  • 10

    Mario Badescu Drying Lotion for All Skin Types| Blemish Spot Treatment with Salicylic Acid and Sulfur | Dries Surface Blemishes | 1 Fl Oz
    Mario Badescu
    8.5
    Good

    Mario Badescu Drying Lotion for All Skin Types| Blemish Spot Treatment with Salicylic Acid and Sulfur | Dries Surface Blemishes | 1 Fl Oz

    • is discontinued by manufacturer:No
    • product dimensions:2.5 x 2.5 x 2 inches 1 ounces
    • country of origin:USA
    • upc:785364133082 785364130081 885790423518
    • asin:B0017SWIU4