10 Best pimple spot treatments of 2025

Save up to 35% off

Best Choice

1

Murad
Murad Rapid Relief Acne Spot Treatment – Acne Control Max Strength 2% Salicylic Acid Invisible Gel Spot Solution for Fast Acne Relief - Reduces Blemish Size and Redness Within 4 Hours, 0.5 Oz

14% Off
Main highlights

Fast Acne Relief with Science-Backed Formula
Murad Rapid Relief Acne Spot Treatment offers fast acne relief using 2% salicylic acid, scientifically proven for effectiveness.

Ideal for On-the-Spot Application
Best used for targeted acne treatment, apply directly to blemishes for quick results.

Smooth Skin Finish Praised by Users
Users love that it leaves skin feeling smooth without dryness, a standout feature.
9.9

Exceptional

Our Rating
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

CeraVe
CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz

21% Off
Main highlights

Advanced Exfoliation and Hydration
Combines BHA and AHA to clear acne, smooth skin, and maintain moisture.

Ideal for Sensitive and Acne-Prone Skin
Perfect for those seeking gentle yet effective acne treatment.

Unmatched Performance and Affordability
Praised for its effective results and affordable price point.
9.8

Exceptional

Our Rating

8.9
worth the money

8.9
For Gentle skin

8.7
Aroma
3

AcneFree
AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1

35% Off
Main highlights

Maximum Strength Benzoyl Peroxide
Contains 10% benzoyl peroxide for effective acne treatment and redness control.

Ideal for Spot Treatment
Best used for treating individual pimples and mild recurring acne.

Convenient Flip-Cap Design
Praised for its easy-to-use flip-cap that prevents loss and simplifies application.
9.6

Exceptional

Our Rating

9.7
quality of ingredients

8.4
worth the money

8.0
Sheerness
4

Mighty Patch
Mighty Patch™ Original patch from Hero Cosmetics - Hydrocolloid Acne Pimple Patch for Covering Zits and Blemishes in Face and Skin, Vegan-friendly and Not Tested on Animals (36 Count)
Main highlights

Overnight Pimple Treatment
Mighty Patch Original uses hydrocolloid to visibly improve pimples overnight, reducing redness and size.

Best for Night Use
Ideal for overnight use, these patches stay on securely while you sleep.

Customer Praised Adhesion
Customers love the strong adhesion that keeps the patch in place all night.
9.5

Excellent

Our Rating

9.5
Simple to use

9.5
Simple to take off

9.5
Attachment
5

Neutrogena
Neutrogena On-The-Spot Acne Treatment Gel with Benzoyl Peroxide - Gentle Face Acne Medicine for Acne Prone Skin, 0.75 oz

33% Off
Main highlights

Effective Acne Treatment with Benzoyl Peroxide
.75-ounce tube with 2.5% benzoyl peroxide fights acne gently.

Ideal for Daily Use on Acne-Prone Skin
Use up to three times daily without over-drying.

Praised for Quick and Visible Results
Customers appreciate its effectiveness and quick results.
9.4

Excellent

Our Rating
See Today’s Deals & Prices
6

Mario Badescu
Mario Badescu Drying Lotion for All Skin Types| Blemish Spot Treatment with Salicylic Acid and Sulfur | Dries Surface Blemishes | 1 Fl Oz

30% Off
Main highlights

Key Features and Benefits
Fast-acting acne treatment, reduces blemish size overnight, suitable for occasional use.

Ideal Use Cases
Best for emergency acne treatment, spot application for quick results.

Praised Feature
Highly effective in reducing blemish size and duration.
9.3

Excellent

Our Rating

8.0
For Gentle skin

8.0
Aroma

8.0
Moisturizing
7

Neutrogena
Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 10% Benzoyl Peroxide Acne Treatment Medication, Pimple Cream for Acne Prone Skin Care, 1 oz

27% Off
Main highlights

Maximum Strength Benzoyl Peroxide
Contains 10% benzoyl peroxide for rapid acne reduction.

Ideal for Stubborn Acne
Perfect for treating stubborn acne on acne-prone skin.

Quick and Effective Results
Praised for reducing acne size and redness within hours.
9.1

Excellent

Our Rating

8.7
Aroma

8.4
Fashion

8.2
worth the money
8

Clean & Clear
Clean & Clear, Persa-Gel 10 Acne Spot Treatment, Maximum Strength, 1 Oz

25% Off
Main highlights

Maximum Strength Formula
Contains 10% benzoyl peroxide for effective acne treatment.

Ideal for Spot Treatment
Perfect for inflamed acne bumps and quick results.

Highly Praised for Quick Results
Users report visible reduction in acne overnight.
9.0

Excellent

Our Rating
9

Differin
Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

20% Off
Main highlights

Effective Acne Treatment
Differin Gel targets clogged pores and inflammation, reducing breakouts and improving skin texture and tone.

Ideal for Acne-Prone Skin
Best for those with acne-prone, sensitive skin needing a gentle retinoid treatment.

Praised for Clear Skin
Customers love its ability to keep skin clear and smooth, even with hormonal or diet-related acne.
8.8

Very Good

Our Rating

8.2
worth the money

8.0
Aroma

8.0
Fashion
10

KEYCONCEPTS
PatchRx Pimple Patches for Face (120 Patches), Hydrocolloid Acne Patches with Tea Tree Oil, Pimple Patch Pimple Stickers - Hydrocolloid Patch Acne Dots - Acne Pimple Patches For Face - Zit Patches

28% Off
Main highlights

Hydrocolloid with Tea Tree Oil
These patches combine hydrocolloid technology with tea tree oil to soothe and absorb impurities effectively.

Day and Night Versatility
Ideal for acne treatment anytime, these patches work in 6-8 hours, suitable for both day and night use.

Strong Adhesion and Discretion
Praised for good adhesion and being discreet under masks, making them versatile for daily wear.
8.6

Very Good

Our Rating

9.3
Simple to use

9.3
Simple to take off

8.7
Attachment

10 Best pimple spot treatments of 2025

1

Murad Rapid Relief Acne Spot Treatment – Acne Control Max Strength 2% Salicylic Acid Invisible Gel Spot Solution for Fast Acne Relief - Reduces Blemish Size and Redness Within 4 Hours, 0.5 Oz

How do we rank?

How do we rank?

Analyzing top stores

2

CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz

8.9

8.9

8.7

3

AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1

9.7

8.4

8.0

4

Mighty Patch™ Original patch from Hero Cosmetics - Hydrocolloid Acne Pimple Patch for Covering Zits and Blemishes in Face and Skin, Vegan-friendly and Not Tested on Animals (36 Count)

9.5

9.5

9.5

5

Neutrogena On-The-Spot Acne Treatment Gel with Benzoyl Peroxide - Gentle Face Acne Medicine for Acne Prone Skin, 0.75 oz

6

Mario Badescu Drying Lotion for All Skin Types| Blemish Spot Treatment with Salicylic Acid and Sulfur | Dries Surface Blemishes | 1 Fl Oz

8.0

8.0

8.0

7

Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 10% Benzoyl Peroxide Acne Treatment Medication, Pimple Cream for Acne Prone Skin Care, 1 oz

8.7

8.4

8.2

8

Clean & Clear, Persa-Gel 10 Acne Spot Treatment, Maximum Strength, 1 Oz

9

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

8.2

8.0

8.0

10

PatchRx Pimple Patches for Face (120 Patches), Hydrocolloid Acne Patches with Tea Tree Oil, Pimple Patch Pimple Stickers - Hydrocolloid Patch Acne Dots - Acne Pimple Patches For Face - Zit Patches

9.3

9.3

8.7

Sign up and get exclusive special deals