February 21, 2026

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10 Best paulas choice clinicals 20 of 2026

Save up to 15% off

1

Paula's Choice

Paula's Choice 5% Niacinamide Body Serum + CLINICAL 20% Niacinamide Treatment, Face & Body Kit for Discoloration, Redness & Bumpy Skin, All Skin Types Including Acne-Prone, Set of 2

15% Off
9.8

Exceptional

Our Rating
How do we rank?

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Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
2

Paula's Choice
Paula's Choice CLINICAL 1% Retinol Face Treatment with Peptides, Vitamin C & Licorice Extract, Anti-Aging Skin Care Serum, Fine Lines & Wrinkles, Fragrance Free, 1 Fl Oz
Main highlights

Key Features
Advanced retinol formula targets fine lines, wrinkles, and uneven tone, offering hydration and natural radiance with sustainable packaging.

Ideal Use Cases
Perfect for all skin types, especially those addressing aging signs like wrinkles and uneven skin tone seeking lightweight hydration.

Customer Praise
Users laud its effectiveness on fine lines without irritation, highlighting noticeable improvements in skin texture and tone.
9.5

Excellent

Our Rating

8.0
Fashion

8.0
Aroma

8.0
Moisturizing
3

Paula's Choice
Paula's Choice CLINICAL 20% Niacinamide Vitamin B3 Concentrated Face Serum, Anti-Aging Serum for Face, Treatment for Discoloration & Minimizing Large Pores, Fragrance-Free, 0.67oz
Main highlights

Advanced Niacinamide Formula
Contains a 20% concentration of niacinamide for anti-aging and pore minimizing.

Best for Uneven Skin Tone
Ideal for those seeking to improve skin texture and tone.

Praised for Smoother Skin
Customers love its ability to smooth skin texture effectively.
Key specs
- Vitamin C:Present
- Effects:Brighten, refine pores
- Skin Type:N/A
- Niacinamide:N/A
- Hyaluronic Acid:N/A
9.3

Excellent

Our Rating

8.7
Aroma

8.0
Moisturizing

8.0
Sheerness
4

Paula's Choice
Paula's Choice CLINICAL 20% Niacinamide Vitamin B3 Concentrated Face Serum, Anti-Aging Serum for Face, Treatment for Discoloration & Minimizing Large Pores, Fragrance-Free, 0.67oz
Main highlights

Advanced Niacinamide Formula
Contains a 20% concentration of niacinamide for anti-aging and pore minimizing.

Best for Uneven Skin Tone
Ideal for those seeking to improve skin texture and tone.

Praised for Smoother Skin
Customers love its ability to smooth skin texture effectively.
Key specs
- Vitamin C:Present
- Effects:Brighten, refine pores
- Skin Type:N/A
- Niacinamide:N/A
- Hyaluronic Acid:N/A
9.1

Excellent

Our Rating

8.7
Aroma

8.0
Moisturizing

8.0
Sheerness
5

Paula's Choice

Paula’s Choice CLINICAL 20% Niacinamide Serum Treatment + Travel Size 2% BHA Salicylic Acid Liquid Exfoliant Duo, Set of 2

14% Off
9.0

Excellent

Our Rating
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6

Paula's Choice
Paula's Choice CLINICAL 1% Retinol Face Treatment with Peptides, Vitamin C & Licorice Extract, Anti-Aging Skin Care Serum, Fine Lines & Wrinkles, Fragrance Free, 1 Fl Oz
Main highlights

Key Features
Advanced retinol formula targets fine lines, wrinkles, and uneven tone, offering hydration and natural radiance with sustainable packaging.

Ideal Use Cases
Perfect for all skin types, especially those addressing aging signs like wrinkles and uneven skin tone seeking lightweight hydration.

Customer Praise
Users laud its effectiveness on fine lines without irritation, highlighting noticeable improvements in skin texture and tone.
8.7

Very Good

Our Rating

8.0
Fashion

8.0
Aroma

8.0
Moisturizing
7

Paula's Choice
Paula's Choice CLINICAL 0.3% Retinol + 2% Bakuchiol Face Serum Treatment, Anti-Aging Serum for Face with Ceramides, Hylauronic Acid, Vitamin C & E, Deep Wrinkles & Fine Lines, Fragrance-Free, 1 oz
Main highlights

Key Features
Triple-action blend with Retinol, Bakuchiol & Peptides boosts collagen, targeting aging signs for a radiant look. Sustainable packaging.

Ideal Use
Perfect for all skin types, addressing deep wrinkles, discoloration, and hyperpigmentation, enhancing skin elasticity and texture.

Customer Praise
94% users saw improved elasticity, 90% noted better skin texture, highlighting its effectiveness in combating signs of aging without irritation.
8.5

Good

Our Rating

9.9
Fashion

9.1
Aroma

8.7
Moisturizing
8

Paula's Choice
Paula's Choice CLINICAL 0.3% Retinol + 2% Bakuchiol Face Serum Treatment, Anti-Aging Serum for Face with Ceramides, Hylauronic Acid, Vitamin C & E, Deep Wrinkles & Fine Lines, Fragrance-Free, 1 oz
Main highlights

Key Features
Triple-action blend with Retinol, Bakuchiol & Peptides boosts collagen, targeting aging signs for a radiant look. Sustainable packaging.

Ideal Use
Perfect for all skin types, addressing deep wrinkles, discoloration, and hyperpigmentation, enhancing skin elasticity and texture.

Customer Praise
94% users saw improved elasticity, 90% noted better skin texture, highlighting its effectiveness in combating signs of aging without irritation.
8.3

Good

Our Rating

9.9
Fashion

9.1
Aroma

8.7
Moisturizing
9

Paula's Choice
Paula's Choice CLINICAL Discoloration Repair Face Serum with Tranexamic Acid, Facial Serum for Stubborn Dark Spots, Post-Acne Marks & Sun Damage, Fragrance-Free, 1 Fl Oz
Main highlights

Key Features
Clinical-strength brighteners like 3% tranexamic acid and 5% niacinamide target dark spots, discoloration, with sustainable packaging.

Ideal Use Cases
Perfect for fading mask-like discoloration, melasma, hyperpigmentation on all skin types and tones, including post-acne marks.

Customer Praise
Most reviews highlight its effectiveness in visibly reducing dark spots and improving evenness of skin tone without irritation.
8.0

Good

Our Rating

8.0
Moisturizing

8.0
Light weight

8.0
Aroma
10

Paula's Choice
Paula's Choice CLINICAL Discoloration Repair Face Serum with Tranexamic Acid, Facial Serum for Stubborn Dark Spots, Post-Acne Marks & Sun Damage, Fragrance-Free, 1 Fl Oz
Main highlights

Key Features
Clinical-strength brighteners like 3% tranexamic acid and 5% niacinamide target dark spots, discoloration, with sustainable packaging.

Ideal Use Cases
Perfect for fading mask-like discoloration, melasma, hyperpigmentation on all skin types and tones, including post-acne marks.

Customer Praise
Most reviews highlight its effectiveness in visibly reducing dark spots and improving evenness of skin tone without irritation.
7.7

Good

Our Rating

8.0
Moisturizing

8.0
Light weight

8.0
Aroma

10 Best paulas choice clinicals 20 of 2026

1

Paula's Choice 5% Niacinamide Body Serum + CLINICAL 20% Niacinamide Treatment, Face & Body Kit for Discoloration, Redness & Bumpy Skin, All Skin Types Including Acne-Prone, Set of 2

How do we rank?

How do we rank?

Analyzing top stores

2

Paula's Choice CLINICAL 1% Retinol Face Treatment with Peptides, Vitamin C & Licorice Extract, Anti-Aging Skin Care Serum, Fine Lines & Wrinkles, Fragrance Free, 1 Fl Oz

8.0

8.0

8.0

3

Paula's Choice CLINICAL 20% Niacinamide Vitamin B3 Concentrated Face Serum, Anti-Aging Serum for Face, Treatment for Discoloration & Minimizing Large Pores, Fragrance-Free, 0.67oz

8.7

8.0

8.0

4

Paula's Choice CLINICAL 20% Niacinamide Vitamin B3 Concentrated Face Serum, Anti-Aging Serum for Face, Treatment for Discoloration & Minimizing Large Pores, Fragrance-Free, 0.67oz

8.7

8.0

8.0

5

Paula’s Choice CLINICAL 20% Niacinamide Serum Treatment + Travel Size 2% BHA Salicylic Acid Liquid Exfoliant Duo, Set of 2

6

Paula's Choice CLINICAL 1% Retinol Face Treatment with Peptides, Vitamin C & Licorice Extract, Anti-Aging Skin Care Serum, Fine Lines & Wrinkles, Fragrance Free, 1 Fl Oz

8.0

8.0

8.0

7

Paula's Choice CLINICAL 0.3% Retinol + 2% Bakuchiol Face Serum Treatment, Anti-Aging Serum for Face with Ceramides, Hylauronic Acid, Vitamin C & E, Deep Wrinkles & Fine Lines, Fragrance-Free, 1 oz

9.9

9.1

8.7

8

Paula's Choice CLINICAL 0.3% Retinol + 2% Bakuchiol Face Serum Treatment, Anti-Aging Serum for Face with Ceramides, Hylauronic Acid, Vitamin C & E, Deep Wrinkles & Fine Lines, Fragrance-Free, 1 oz

9.9

9.1

8.7

9

Paula's Choice CLINICAL Discoloration Repair Face Serum with Tranexamic Acid, Facial Serum for Stubborn Dark Spots, Post-Acne Marks & Sun Damage, Fragrance-Free, 1 Fl Oz

8.0

8.0

8.0

10

Paula's Choice CLINICAL Discoloration Repair Face Serum with Tranexamic Acid, Facial Serum for Stubborn Dark Spots, Post-Acne Marks & Sun Damage, Fragrance-Free, 1 Fl Oz

8.0

8.0

8.0

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