October 21, 2025

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10 Best otc probiotics of 2025

Save up to 56% off

Best Choice

1

Florastor
Florastor Probiotics for Digestive and Immune Health, 100 Capsules, Probiotics for Women & Men, Helps Flush Out Bad Bacteria, Boosts The Good with Our Unique Strain Saccharomyces Boulardii
Main highlights

Dual Action Support
Florastor probiotic strengthens digestive health and boosts immunity using Saccharomyces boulardii CNCM I-745.

Ideal for Digestive Recovery
Perfect for individuals recovering from antibiotics or digestive disorders like IBS and Crohn's.

Highly Praised Digestive Relief
Customers appreciate its effectiveness in normalizing bowel movements and reducing bloating.
Key specs
- Form:Capsules
- Strains:Saccharomyces boulardii CNCM I-745
- Features:Shelf stable, vegetarian
- Dosage:2 capsules 1-2 times daily
- CFU:N/A
9.8

Exceptional

Our Rating

9.7
simple to consume

9.7
Simple to use

9.5
Comfort
How do we rank?

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Real users impact

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Based on millions of stores and reviews

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Value for Money

2

Culturelle
Culturelle Pro Strength Daily Probiotics For Digestive Health (2 Month Supply) with Prebiotics for Women & Men, Supports Occasional Diarrhea, Gas & Bloating, Gluten & Soy Free, 60 Count
Main highlights

Digestive Health Support
Contains 12 billion CFUs of Lactobacillus rhamnosus LGG for digestive balance.

Ideal for Sensitive Stomachs
Helps manage occasional diarrhea, gas, and bloating; great for IBS or Crohn's.

Highly Recommended by Users
Praised for cost-effectiveness and noticeable improvement in digestive issues.
9.6

Exceptional

Our Rating

9.9
Comfort

9.7
simple to consume

9.7
Freshness
3

Nature's Bounty
Nature's Bounty Lactobacillus Acidophilus Probiotic Supplement - Daily Probiotic for Women/Men Digestive Health, 100 Million Organisms, Vegetarian, 1 Serving per Day, 120 Tablets
Main highlights

Provides Friendly Bacteria
Contains 100 million active Lactobacillus Acidophilus cultures for digestive and immune health.

Ideal for Daily Use
One-per-day tablet, perfect for maintaining gut health with ease.

Trusted Brand
Customers appreciate Nature's Bounty's reliability and product effectiveness.
Key specs
- Form:Tablet
- Strains:Lactobacillus Acidophilus
- Features:Gluten, dairy, wheat free
- Dosage:One tablet daily
- CFU:100 million
9.3

Excellent

Our Rating

9.5
simple to consume

9.1
worth the money

8.9
Flavor
4

OLLY
OLLY Probiotic + Prebiotic Gummy, Digestive Support and Gut Health, 500 Million CFUs, Fiber, Adult Chewable Supplement for Men and Women, Peach, 30 Day Supply - 30 Count

20% Off
Main highlights

Powerful Digestive Support
OLLY Probiotic + Prebiotic gummies offer 500 million CFUs to enhance gut health and digestion.

Convenient Daily Use
Ideal for adults seeking easy, chewable digestive support without needing food or water.

Delicious Flavor
Customers love the naturally flavored Peachy Peach taste, enhancing the supplement experience.
Key specs
- Probiotic Strains:Bacillus Coagulans
- Formulation:Gummy
- Prebiotic Type:Prebiotic Fiber
- Serving Size:One gummy daily
- Country of Origin:USA
9.1

Excellent

Our Rating

9.3
Flavor

8.0
Comfort

8.0
worth the money
5

Nature's Bounty
Nature's Bounty Probiotic 10 Daily Probiotic Supplement for Digestive, Immune, and Upper Respiratory Support, Ultra Strength, 30 Capsules 1 Pack

56% Off
Main highlights

Ultra Strength Probiotic Formula
Contains 20 billion CFU and 10 unique strains for digestive and immune support.

Ideal for Digestive and Immune Health
Supports individuals with IBS, constipation, and digestive autoimmune disorders.

Highly Praised for Effective Results
Customers appreciate its effectiveness in maintaining gut health and reducing medication needs.
Key specs
- Form:Capsule
- Strains:10 unique strains
- Features:Supports digestive and immune health
- Dosage:One capsule per day
- CFU:20 billion
8.8

Very Good

Our Rating

9.3
simple to consume

8.7
worth the money

8.2
Flavor
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6

Culturelle
Culturelle Daily Probiotic Gummies for Women & Men, Berry Flavor, 52 Count, Naturally-Sourced Daily Probiotic + Prebiotic for Digestive Health, Non-GMO & Vegan

11% Off
Main highlights

Probiotic Prebiotic Formula
Culturelle Daily Probiotic Gummies support digestive health with 2 billion CFUs and prebiotics, promoting a balanced gut microbiome.

Ideal for Daily Wellness Routine
Perfect for individuals seeking an easy, tasty way to enhance digestive health daily with naturally sourced ingredients.

Praised for Taste and Convenience
Customers love the berry flavor and gummy form, making it a pleasant addition to their daily routine.
8.5

Good

Our Rating

9.5
simple to consume

9.1
Comfort

8.7
quality of ingredients
7

Physician's CHOICE
Physician's Choice Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 30ct

18% Off
Main highlights

Digestive and Gut Support
Max Strength General Purpose Probiotic with 60B CFU supports digestive and gut health for a balanced microbiome.

Best for Digestive Issues
Ideal for occasional constipation, diarrhea, gas, and bloating relief in both women and men.

Customer Praised Effectiveness
Users report significant improvements in digestion and energy levels after consistent use.
8.4

Good

Our Rating

9.7
simple to consume

9.5
worth the money

9.5
quality of ingredients
8

OLLY

OLLY Probiotic Gummy, 1 Billion CFUs, Immune and Digestive Support, Chewable Probiotic Supplement, Mango, 80 Count
8.3

Good

Our Rating
9

Align

Align Probiotic, Pro Formula, Probiotics for Women and Men, Daily Probiotic Supplement, Helps Soothe Occasional Bloating & Gas*, #1 Doctor Recommended Brand‡, 30 Capsules (Packaging May Vary)
8.2

Good

Our Rating
10

Nature's Way
Nature's Way Women's Probiotic Pearls, Supports Vaginal and Digestive Health*, 1 Billion Live Cultures, No Refrigeration Required, 30 Softgels (Packaging May Vary)
Main highlights

Daily Probiotic Support
Contains 1 billion active Lactobacilli cultures to support digestive and vaginal health.

Convenient and Travel-Friendly
Small, easy-to-swallow pearls require no refrigeration, ideal for on-the-go use.

Highly Praised Swallowability
Customers love the small, round shape that's easy to swallow.
8.1

Good

Our Rating

9.9
simple to consume

9.7
Flavor

8.9
worth the money

10 Best otc probiotics of 2025

1

Florastor Probiotics for Digestive and Immune Health, 100 Capsules, Probiotics for Women & Men, Helps Flush Out Bad Bacteria, Boosts The Good with Our Unique Strain Saccharomyces Boulardii

9.7

9.7

9.5

How do we rank?

How do we rank?

Analyzing top stores

2

Culturelle Pro Strength Daily Probiotics For Digestive Health (2 Month Supply) with Prebiotics for Women & Men, Supports Occasional Diarrhea, Gas & Bloating, Gluten & Soy Free, 60 Count

9.9

9.7

9.7

3

Nature's Bounty Lactobacillus Acidophilus Probiotic Supplement - Daily Probiotic for Women/Men Digestive Health, 100 Million Organisms, Vegetarian, 1 Serving per Day, 120 Tablets

9.5

9.1

8.9

4

OLLY Probiotic + Prebiotic Gummy, Digestive Support and Gut Health, 500 Million CFUs, Fiber, Adult Chewable Supplement for Men and Women, Peach, 30 Day Supply - 30 Count

9.3

8.0

8.0

5

Nature's Bounty Probiotic 10 Daily Probiotic Supplement for Digestive, Immune, and Upper Respiratory Support, Ultra Strength, 30 Capsules 1 Pack

9.3

8.7

8.2

6

Culturelle Daily Probiotic Gummies for Women & Men, Berry Flavor, 52 Count, Naturally-Sourced Daily Probiotic + Prebiotic for Digestive Health, Non-GMO & Vegan

9.5

9.1

8.7

7

Physician's Choice Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 30ct

9.7

9.5

9.5

8

OLLY Probiotic Gummy, 1 Billion CFUs, Immune and Digestive Support, Chewable Probiotic Supplement, Mango, 80 Count

9

Align Probiotic, Pro Formula, Probiotics for Women and Men, Daily Probiotic Supplement, Helps Soothe Occasional Bloating & Gas*, #1 Doctor Recommended Brand‡, 30 Capsules (Packaging May Vary)

10

Nature's Way Women's Probiotic Pearls, Supports Vaginal and Digestive Health*, 1 Billion Live Cultures, No Refrigeration Required, 30 Softgels (Packaging May Vary)

9.9

9.7

8.9

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