10 Best otc probiotics of 2025

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Best Choice

1

Florastor
Florastor Probiotics for Digestive and Immune Health, 100 Capsules, Probiotics for Women & Men, Helps Flush Out Bad Bacteria, Boosts The Good with Our Unique Strain Saccharomyces Boulardii
Main highlights

Dual Action Support
Florastor probiotic strengthens digestive health and boosts immunity using Saccharomyces boulardii CNCM I-745.

Ideal for Digestive Recovery
Perfect for individuals recovering from antibiotics or digestive disorders like IBS and Crohn's.

Highly Praised Digestive Relief
Customers appreciate its effectiveness in normalizing bowel movements and reducing bloating.
9.8

Exceptional

Our Rating

9.7
simple to consume

9.7
Simple to use

9.5
Comfort
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Value for Money

2

Culturelle
Culturelle Pro Strength Daily Probiotics For Digestive Health (2 Month Supply) with Prebiotics for Women & Men, Supports Occasional Diarrhea, Gas & Bloating, Gluten & Soy Free, 60 Count
Main highlights

Digestive Health Support
Contains 12 billion CFUs of Lactobacillus rhamnosus LGG for digestive balance.

Ideal for Sensitive Stomachs
Helps manage occasional diarrhea, gas, and bloating; great for IBS or Crohn's.

Highly Recommended by Users
Praised for cost-effectiveness and noticeable improvement in digestive issues.
9.6

Exceptional

Our Rating

9.9
Comfort

9.7
simple to consume

9.7
Freshness
3

Nature's Bounty
Nature's Bounty Acidophilus Probiotic, Daily Probiotic Supplement, Digestive Health, 200 Tablets, Twin Pack

22% Off
Main highlights

Provides Friendly Bacteria
Contains 100 million active Lactobacillus acidophilus cultures for digestive health support.

Ideal for Daily Use
One-per-day supplement, easy to incorporate into daily routine with meals.

Praised for Effectiveness
Customers appreciate its mildness on the stomach and comparable effectiveness to pricier brands.
9.5

Excellent

Our Rating

9.5
simple to consume

9.3
quality of ingredients

9.1
worth the money
4

OLLY
OLLY Probiotic + Prebiotic Gummy, Digestive Support and Gut Health, 500 Million CFUs, Fiber, Adult Chewable Supplement for Men and Women, Peach, 30 Day Supply - 30 Count

20% Off
Main highlights

Powerful Digestive Support
OLLY Probiotic + Prebiotic gummies offer 500 million CFUs to enhance gut health and digestion.

Convenient Daily Use
Ideal for adults seeking easy, chewable digestive support without needing food or water.

Delicious Flavor
Customers love the naturally flavored Peachy Peach taste, enhancing the supplement experience.
9.3

Excellent

Our Rating

9.3
Flavor

8.0
Comfort

8.0
worth the money
5

Physician's CHOICE
Physician's Choice Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 30ct

26% Off
Main highlights

Digestive and Gut Support
Max Strength General Purpose Probiotic with 60B CFU supports digestive and gut health for a balanced microbiome.

Best for Digestive Issues
Ideal for occasional constipation, diarrhea, gas, and bloating relief in both women and men.

Customer Praised Effectiveness
Users report significant improvements in digestion and energy levels after consistent use.
9.2

Excellent

Our Rating

9.7
simple to consume

9.5
worth the money

9.5
quality of ingredients
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6

Nature's Bounty
Nature's Bounty Probiotic 10 Daily Probiotic Supplement for Digestive, Immune, and Upper Respiratory Support, Ultra Strength, 30 Capsules 1 Pack

56% Off
Main highlights

Ultra Strength Probiotic Formula
Contains 20 billion CFU and 10 unique strains for digestive and immune support.

Ideal for Digestive and Immune Health
Supports individuals with IBS, constipation, and digestive autoimmune disorders.

Highly Praised for Effective Results
Customers appreciate its effectiveness in maintaining gut health and reducing medication needs.
8.9

Very Good

Our Rating

9.3
simple to consume

8.7
worth the money

8.2
Flavor
7

Culturelle
Culturelle Daily Probiotic Gummies for Women & Men, Berry Flavor, 52 Count, Naturally-Sourced Daily Probiotic + Prebiotic for Digestive Health, Non-GMO & Vegan

11% Off
Main highlights

Probiotic Prebiotic Formula
Culturelle Daily Probiotic Gummies support digestive health with 2 billion CFUs and prebiotics, promoting a balanced gut microbiome.

Ideal for Daily Wellness Routine
Perfect for individuals seeking an easy, tasty way to enhance digestive health daily with naturally sourced ingredients.

Praised for Taste and Convenience
Customers love the berry flavor and gummy form, making it a pleasant addition to their daily routine.
8.6

Very Good

Our Rating

9.5
simple to consume

9.1
Comfort

8.7
quality of ingredients
8

Physician's CHOICE
Physician's CHOICE Vaginal Probiotics for Women - pH Balance, Odor Control, Yeast Balance, Vaginal Flora & Feminine Health - 6B CFU with Organic Prebiotics and Cranberry Extract - 30 CT

25% Off
Main highlights

Unique Licorice Root Formula
Supports vaginal health with probiotics, prebiotic, and cranberry extract for pH balance and odor control.

Ideal for Feminine Health
Designed for women seeking optimal vaginal microbiome and yeast balance with daily confidence.

Praised for Noticeable Results
Users report improved comfort and confidence within the first month of use.
8.4

Good

Our Rating
9

OLLY

OLLY Probiotic Gummy, 1 Billion CFUs, Immune and Digestive Support, Chewable Probiotic Supplement, Mango, 80 Count
8.3

Good

Our Rating
10

NATURE TARGET
NATURE TARGET Probiotics for Women, 100 Billion CFUs Probiotic with Digestive Enzymes & Prebiotics, Vaginal Probiotics with Cranberry for Urinary Tract Health, pH Balance, 90 Veggie Capsules
Main highlights

Gut Health Solution
Combines 100 Billion CFUs probiotics, prebiotics, enzymes, and multivitamins for comprehensive gut health support.

Women's Health Focus
Ideal for supporting vaginal and urinary tract health with cranberry and D-mannose.

Effective Prebiotics
Praised for its effectiveness in improving gut health and digestion.
8.2

Good

Our Rating

10 Best otc probiotics of 2025

1

Florastor Probiotics for Digestive and Immune Health, 100 Capsules, Probiotics for Women & Men, Helps Flush Out Bad Bacteria, Boosts The Good with Our Unique Strain Saccharomyces Boulardii

9.7

9.7

9.5

How do we rank?

How do we rank?

Analyzing top stores

2

Culturelle Pro Strength Daily Probiotics For Digestive Health (2 Month Supply) with Prebiotics for Women & Men, Supports Occasional Diarrhea, Gas & Bloating, Gluten & Soy Free, 60 Count

9.9

9.7

9.7

3

Nature's Bounty Acidophilus Probiotic, Daily Probiotic Supplement, Digestive Health, 200 Tablets, Twin Pack

9.5

9.3

9.1

4

OLLY Probiotic + Prebiotic Gummy, Digestive Support and Gut Health, 500 Million CFUs, Fiber, Adult Chewable Supplement for Men and Women, Peach, 30 Day Supply - 30 Count

9.3

8.0

8.0

5

Physician's Choice Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 30ct

9.7

9.5

9.5

6

Nature's Bounty Probiotic 10 Daily Probiotic Supplement for Digestive, Immune, and Upper Respiratory Support, Ultra Strength, 30 Capsules 1 Pack

9.3

8.7

8.2

7

Culturelle Daily Probiotic Gummies for Women & Men, Berry Flavor, 52 Count, Naturally-Sourced Daily Probiotic + Prebiotic for Digestive Health, Non-GMO & Vegan

9.5

9.1

8.7

8

Physician's CHOICE Vaginal Probiotics for Women - pH Balance, Odor Control, Yeast Balance, Vaginal Flora & Feminine Health - 6B CFU with Organic Prebiotics and Cranberry Extract - 30 CT

9

OLLY Probiotic Gummy, 1 Billion CFUs, Immune and Digestive Support, Chewable Probiotic Supplement, Mango, 80 Count

10

NATURE TARGET Probiotics for Women, 100 Billion CFUs Probiotic with Digestive Enzymes & Prebiotics, Vaginal Probiotics with Cranberry for Urinary Tract Health, pH Balance, 90 Veggie Capsules

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