10 Best otc muscle relaxers of 2025

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Best Choice

1

Dee Cee Laboratories
Dee Cee Labs Formula 303 Maximum Strength All-Natural Relaxant Tablets, 250 Tablets; All-Natural Relaxant containing Magnesium for Sore Muscles, Passion Flower, and Valerian Root
Main highlights

Natural Ingredients for Relaxation
Formula 303 combines valerian root, passion flower, and magnesium for muscle relaxation and stress relief.

Ideal for Muscle and Stress Relief
Best used for easing muscle spasms, tension, and stress naturally.

Effective Sciatic Pain Relief
Customers praise its effectiveness in relieving sciatic pain and improving mobility.
Key specs
- Usage:Muscle spasm, stress relief
- Gluten-Free:Yes
- Form:Tablets
- Ingredients:Valerian Root, Passion Flower, Magnesium
- Non-GMO:Yes
9.6

Exceptional

Our Rating

9.3
simple to consume

8.9
pain management

8.0
Flavor
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Value for Money

2

Dee Cee Laboratories
Dee CEE Labs Formula 303 Maximum Strength Tablets, 90 Tablets; All-Natural containing Magnesium for Sore Muscles, Passion Flower, and Valerian Root

18% Off
Main highlights

Natural_Ingredients_Relaxation
Dee Cee Labs Formula 303 uses valerian root, passion flower, and magnesium for stress and muscle relief.

Ideal_for_Muscle_Tension
Best used for muscle spasms, joint relief, and stress management.

Customer_Praised_Effectiveness
Customers appreciate its quick action and effectiveness in muscle relaxation.
Key specs
- Type:Herbal Remedy
- Effectiveness:Muscle, stress relief
- Formulation:Tablet
- Ingredients:Valerian Root, Passion Flower, Magnesium
- Safety:Gluten Free, Non-GMO
9.5

Excellent

Our Rating
3

Oregon's Wild Harvest
Oregon's Wild Harvest Muscle Relax Organic Herbal Supplement Vegan Capsules with Valerian, Hops and Skullcap - 90 Count

21% Off
Main highlights

Vegan Organic Formula
90ct non-GMO pullulan plant-sourced vegan capsules with certified organic Valerian, Skullcap, and Hops.

Ideal for Relaxation
Perfect for muscle relaxation and improving sleep, especially at night.

Highly Effective for Cramps
Praised for relieving menstrual cramps and post-training muscle tension.
9.3

Excellent

Our Rating

9.3
quality of sleep

8.0
worth the money

8.0
pain management
4

Aleve
Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets, Pain Reliever & Fever Reducer, Medicine for Body , 250 Count
Main highlights

12-Hour Pain Relief
Aleve provides up to 12 hours of uninterrupted pain relief, ideal for back and muscle pain.

Ideal for Back Pain
Specially formulated for quick relief from back and muscle pain, perfect for active individuals.

Quick Pain Relief
Customers praise its fast-acting relief for back and muscle pain compared to other variants.
Key specs
- Tablet Form:Small, easy-to-swallow
- Active Ingredient:220 mg naproxen sodium
- Targeted Relief:Back & muscle pain
- Dosage:Use as directed
- Fever Reducer:Yes, for 12+
9.0

Excellent

Our Rating

9.5
worth the money

9.5
pain management
5

Amazon Basic Care

Amazon Basic Care Back and Muscle Pain, 220 mg, 12-Hour Pain Relief, Naproxen Sodium Tablets, Pain Reliever and Fever Reducer, 90 Count
8.8

Very Good

Our Rating
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6

DR. HERBAL WELL
DR.HERBAL WELL Muscle Ease - Joint, Muscle & Nerve Support Fast Acting Relax Comfort Recovery Natural Herbal Supplement - (60 Capsules) MAX-Strength
Main highlights

Fast-Acting Comfort
Muscle Ease delivers quick relief from muscle discomfort, ideal for immediate post-activity recovery.

Ideal for Active Lifestyles
Perfect for athletes, arthritis sufferers, and those in need of muscle recovery.

Praised for Natural Ingredients
Customers appreciate the all-natural, safe formulation that complements existing health routines.
Key specs
- Ginseng Content:Notoginseng Radix Rhizoma
- Formulation:Advanced formula
- Extract Ratio:N/A
- Capsule Count:N/A
- Flavor:N/A
8.7

Very Good

Our Rating
7

Percogesic
Percogesic Backache Relief Pain Reliever, Maximum Strength, 48 Tablets

10% Off
Main highlights

Fast Acting Formula
Percogesic Backache Relief offers quick relief for backaches and muscular pain with its maximum strength formula.

Ideal for Back and Muscle Pain
Best used for relieving backaches, muscle pain, and sciatic discomfort effectively.

Customer Praised Effectiveness
Praised for its fast action and long-lasting relief, similar to other popular brands.
Key specs
- dosing instructions:Easy to swallow tablets
- form:Coated tablets
- active ingredient:Magnesium salicylate
- pain relief:Enhanced pain relief
- flavor:N/A
8.6

Very Good

Our Rating

8.4
worth the money

8.0
pain management
8

Dee Cee Laboratories
Dee CEE Labs Formula 303 Maximum Strength Tablets, 45 Tablets; All-Natural containing Magnesium for Sore Muscles, Passion Flower, and Valerian Root
Main highlights

Natural Relief for Muscle Spasm, Tension, and Stress
Dee Cee Laboratories Formula 303 offers natural relief for muscle spasms, tension, and stress using valerian root, passionflower, and magnesium.

Ideal for Muscle Relaxation and Mild Insomnia
Formula 303 is best used for easing muscle tension, occasional leg cramps, and mild insomnia, promoting overall relaxation without severe side effects.

Highly Praised for Effective Muscle Relaxation
Customers frequently praise Formula 303 for its ability to relax muscles effectively within 20 to 40 minutes, helping with various muscle-related issues.
Key specs
- active ingredient:valerian root, passionflower, magnesium
- product type:herbal remedy
- dosage form:N/A
- skin type:N/A
- number of patches:N/A
8.5

Good

Our Rating

9.3
For teething

8.0
worth the money

8.0
pain management
9

Boiron
Boiron Arnicare Tablets for Pain Relief from Muscle Pain, Joint Soreness, Swelling from Injury or Bruises - 60 Count
Main highlights

NSAID-Free Natural Relief
Provides muscle pain and swelling relief without NSAIDs, gluten-free.

Ideal for Everyday Aches
Perfect for muscle pain, joint soreness, and swelling from injuries.

Highly Praised for Bruising
Customers love its effectiveness in preventing and treating bruising.
8.4

Good

Our Rating

9.3
Simple to use

8.9
worth the money

8.9
Flavor
10

Theraworx
Theraworx Relief for Muscle Cramps Roll-On Fast-Acting Muscle Spasm, Leg Soreness with Magnesium Sulfate - 2.5 oz - 1 Count
Main highlights

Quick Relief and Absorption
Fast-acting formula that absorbs quickly to relieve muscle cramps and soreness.

Convenient Daily Use
Ideal for daily use on muscle cramps, spasms, and soreness.

User-Friendly Application
Roll-on design praised for ease of use and no mess.
Key specs
- Type:Muscle cramp relief
- Effectiveness:Relieves cramps and soreness
- Formulation:Non-greasy, non-oily
- Ingredients:Natural ingredients
- Safety:Safe to use daily
8.3

Good

Our Rating

9.3
Simple to use

8.7
pain management

8.4
worth the money

10 Best otc muscle relaxers of 2025

1

Dee Cee Labs Formula 303 Maximum Strength All-Natural Relaxant Tablets, 250 Tablets; All-Natural Relaxant containing Magnesium for Sore Muscles, Passion Flower, and Valerian Root

9.3

8.9

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Dee CEE Labs Formula 303 Maximum Strength Tablets, 90 Tablets; All-Natural containing Magnesium for Sore Muscles, Passion Flower, and Valerian Root

3

Oregon's Wild Harvest Muscle Relax Organic Herbal Supplement Vegan Capsules with Valerian, Hops and Skullcap - 90 Count

9.3

8.0

8.0

4

Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets, Pain Reliever & Fever Reducer, Medicine for Body , 250 Count

9.5

9.5

5

Amazon Basic Care Back and Muscle Pain, 220 mg, 12-Hour Pain Relief, Naproxen Sodium Tablets, Pain Reliever and Fever Reducer, 90 Count

6

DR.HERBAL WELL Muscle Ease - Joint, Muscle & Nerve Support Fast Acting Relax Comfort Recovery Natural Herbal Supplement - (60 Capsules) MAX-Strength

7

Percogesic Backache Relief Pain Reliever, Maximum Strength, 48 Tablets

8.4

8.0

8

Dee CEE Labs Formula 303 Maximum Strength Tablets, 45 Tablets; All-Natural containing Magnesium for Sore Muscles, Passion Flower, and Valerian Root

9.3

8.0

8.0

9

Boiron Arnicare Tablets for Pain Relief from Muscle Pain, Joint Soreness, Swelling from Injury or Bruises - 60 Count

9.3

8.9

8.9

10

Theraworx Relief for Muscle Cramps Roll-On Fast-Acting Muscle Spasm, Leg Soreness with Magnesium Sulfate - 2.5 oz - 1 Count

9.3

8.7

8.4

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