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10 Best oral pain reliefs of 2025
Save up to 32% off
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Based on millions of stores and reviews
Shoppers influence our rankings
Analyzing top stores
 3
AnbesolAnbesol Gel Maximum Strength - Instant Oral Pain Relief for Toothaches, Canker Sores, Sore Gums, Denture Pain - 0.33 oz
15% OffMain highlights- 
                        Formulated with Benzocaine for fast, temporary relief from mouth pain.
Instant Oral Pain Relief
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                        Effective for toothaches, canker sores, sore gums, and more.
Ideal for Various Oral Pains
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                        Customers appreciate its immediate numbing effect for pain relief.
Praised for Quick Numbing
 
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OrajelOrajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- From Oral Pain Relief Brand
25% OffMain highlights- 
                        Orajel's 4X clinical strength formula provides fast relief for tooth and gum pain.
Instant Pain Relief Formula
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                        Useful for managing pain before seeing a dentist, offering temporary relief.
Ideal for Pre-Dental Visits
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                        Customers appreciate the immediate pain relief, though it may wear off quickly.
Praised for Immediate Relief
 
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 5
OrajelOrajel 3X for Toothache & Gum Pain: Maximum Gel Tube 0.42oz - From #1 Oral Pain Relief Brand - Orajel for Instant Pain Relief
Main highlights- 
                        Orajel provides immediate pain relief for tooth and gum discomfort with its maximum strength formula containing 20% benzocaine.
Instant Pain Relief with Maximum Strength Formula
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                        Ideal for providing temporary relief from toothaches, gum irritation, and pain from dental aligners, helping avoid emergency dental visits.
Emergency Dental Pain Relief
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                        Customers frequently praise Orajel for its quick pain relief and effectiveness, although some mention the need for frequent reapplication and issues with the tube design.
Fast-Acting and Effective
 
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 6
AnbesolAnbesol Maximum Strength Liquid, Instant Oral Pain Relief for Toothaches, Mouth Sores*, Gum, Braces & Denture Pain, ADA Accepted, 0.41 oz
17% OffMain highlights- 
                        Anbesol Maximum Strength Liquid provides fast relief for toothaches, canker sores, and sore gums with Benzocaine.
Instant Oral Pain Relief
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                        Perfect for use on toothache pain, canker sores, and dental brace discomfort.
Ideal for Oral Discomfort
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                        Customers praise its quick action and reliable pain relief for oral issues.
Fast and Efficient Relief
 
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DenTekDenTek Instant Oral Pain Relief Maximum Strength Kit for Toothaches | 50 Count
32% OffMain highlights- 
                        DenTek kit provides immediate relief from oral pain and toothaches.
Instant Pain Relief
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                        Perfect for temporary relief of sensitive teeth and sore gums.
Ideal for Sensitive Teeth
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                        Customers love the easy-to-use applicators for precise application.
Praised Applicator Design
 
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 9
OrajelOrajel 4X for Toothache & Gum Pain Severe Gel Tube, No Color, 0.25 Ounce
26% OffMain highlights- 
                        Provides fast and effective relief for severe toothache and gum pain.
Clinical Strength Pain Relief
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                        Perfect for quick relief during dental emergencies and gum irritation.
Ideal for Toothache and Gum Pain
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                        Customers appreciate its rapid action in relieving severe oral pain.
Praised for Effective Pain Relief
 
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Oral-BOral-B Mouth Sore Mouthwash Special Care Oral Rinse, Hydrogen Peroxide Mouthwash, 16 fl oz, Mouthwash Alcohol Free
10% OffMain highlights- 
                        Oral-B's special care rinse is alcohol-free, reducing irritation for sensitive mouths while effectively cleansing oral wounds.
Alcohol-Free Formula for Sensitive Mouths
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                        Perfect for users with canker sores, cheek bites, braces, or denture irritations, providing targeted relief and care.
Ideal for Mouth Sores and Irritations
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                        Many users appreciate the product's effectiveness in alleviating mouth sore pain within a short time.
Pain Relief Praised by Users
 
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