July 6, 2025

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10 Best moisturizing eye drops without preservatives of 2025

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Best Choice

1

Systane
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
Main highlights

Fast Hydration and Long-Lasting Relief
Provides quick hydration and sustained relief for dry eyes.

Ideal for Contact Lens Wearers
Safe for use with all contact lenses, perfect for daily wear.

User-Friendly Bottle Design
Customers appreciate the easy-to-use bottle, despite some dispensing issues.
Key specs
- Formula:Contains hyaluronate
- Usage:Safe with contact lenses
- Preservatives:Preservative free
- Hydration:Advanced hydration
- Dimensions:5 x 2 x 4.3 inches
9.8

Exceptional

Our Rating

9.3
Moisturizing

8.7
worth the money

8.0
Simple to use
How do we rank?

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Careful review Our team ensures quality, value, and fit based on real user feedback

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Real users impact

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Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Biotrue
Biotrue Hydration Boost, Preservative-Free Eye Drops for Dry Eyes, Instantly Moisturizes, Rehydrates, Contact Lens Friendly, Refresh & Relieve Eye Irritation, 0.33 FL Oz (Pack of 2)
Main highlights

Key Features and Benefits
Features HA Hyaluronan, antioxidants, and electrolytes for instant moisture. Preservative-free and pH balanced, suitable for contact lens wearers.

Ideal Use Cases
Perfect for relieving dry, irritated eyes caused by extensive screen use, environmental factors, and contact lens wear.

Customer Reviews Highlight
Most praised for providing immediate relief and comfort to dry eyes, with users appreciating its contact lens compatibility.
9.7

Exceptional

Our Rating

9.9
Comfort

9.3
worth the money

9.3
Moisturizing
3

iVIZIA
iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz Bottle

28% Off
Main highlights

Preservative-Free Moisturizing Relief
iVIZIA eye drops offer preservative-free relief, utilizing hydrating polymers and hyaluronic acid for long-lasting moisture.

Ideal for Dry Eye Sufferers
Perfect for individuals with dry eyes, especially contact lens users seeking comfort and hydration.

Highly Praised for Nighttime Use
Customers appreciate its effectiveness in reducing nighttime dryness, allowing restful sleep with fewer interruptions.
Key specs
- Formula:Hydrating polymers, Hyaluronic Acid
- Usage:Contact lens friendly
- Preservatives:Preservative-Free
- Hydration:Moisturizing, holds 1000x moisture
- Dimensions:1.34 x 1.42 x 3.78 inches
9.6

Exceptional

Our Rating

9.9
Moisturizing

8.7
Simple to use

8.0
dispense easily
4

Refresh
Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count
Main highlights

Preservative-Free Formula
Original strength, preservative-free formula that mimics natural tears.

Ideal for Post-Surgery and Dry Eyes
Recommended for use after LASIK and for relieving mild dryness.

Highly Praised Convenience
Single-use vials praised for preventing contamination and ensuring hygiene.
Key specs
- Preservative Free:Yes
- Use Case:After LASIK or surgeries
- Relief Duration:Instantly moisturizes and lubricates
- Eye Comfort:Great for sensitive eyes
- Moisturizing Formula:Original strength, preservative-free
9.4

Excellent

Our Rating

9.5
Simple to use

9.5
Moisturizing

9.3
Comfort
5

Refresh
Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

22% Off
Main highlights

Fast-Acting Relief
Rapidly comforts dry, irritated eyes with a triple-action formula.

Ideal for On-the-Go
Single-use vials are convenient for travel and frequent use.

Praised for Immediate Relief
Customers love the quick relief from dryness and irritation.
9.3

Excellent

Our Rating

9.9
Simple to use

9.3
Moisturizing

8.9
Long life
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6

BLINK

Blink Boost Preservative-Free Lubricating Eye Drops, Eye Care Drops for Dry Eyes, Instant Moisture for Dry Irritated Eyes & Comfort Throughout the Day, Contact Lens Friendly, 10 mL
9.2

Excellent

Our Rating
7

Biotrue

Biotrue Hydration Boost, Preservative-Free Eye Drops for Dry Eyes, Instantly Moisturizes, Rehydrates, Contact Lens Friendly, Refresh & Relieve Eye Irritation, 0.33 FL Oz (Pack of 1)
9.1

Excellent

Our Rating
8

TheraTears
TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials

15% Off
Main highlights

Immediate Long-Lasting Relief
TheraTears provides immediate, long-lasting relief from dry eye symptoms with its unique formula.

Ideal After LASIK
Perfect for post-LASIK care, offering gentle hydration and soothing relief.

Praised Reusability
Customers love the reusability of vials, minimizing waste and maximizing value.
Key specs
- Formula:Lubricant eye drops
- Usage:Immediate relief
- Preservatives:Preservative free
- Hydration:Silky hydration
- Dimensions:4 x 4 x 6 inches
8.9

Very Good

Our Rating

9.9
Simple to use

9.1
Moisturizing

8.9
Comfort
9

Soothe
Soothe Preservative-Free Lubricant Eye Drops, Dry Eye Relief, Moisturizing, for Fast Relief & Gentle Enough for Sensitive Eyes and LASIK Dryness, Single-Use Vials, 30 Count
Main highlights

Long-Lasting Relief
Soothe Lubricant Eye Drops provide fast-acting, long-lasting relief for dry eyes, preventing irritation and discomfort.

Ideal for Sensitive Eyes
Perfect for those with sensitive eyes or post-LASIK dryness, offering gentle, preservative-free moisture.

Highly Praised for Effectiveness
Customers appreciate the effectiveness in soothing dry eye symptoms and the ample quantity in each vial.
Key specs
- Preservative Free:Yes
- Use Case:Dry eyes relief
- Relief Duration:Long-lasting relief
- Eye Comfort:Fast-acting dry eye therapy
- Moisturizing Formula:Soothe Lubricant Eye Drops
8.8

Very Good

Our Rating

9.5
Moisturizing

9.5
Simple to use

8.7
worth the money
10

OCuSOFT
OCuSOFT Retaine MGD Ophthalmic Emulsion - Complete Dry Eye Relief - Soothes Red & Irritated Eyes - 30 Count Preservative-Free Single-Use Containers - 0.01 Fl Oz

36% Off
Main highlights

Moisturizing Lubrication
Retained MGD offers long-lasting relief with preservative-free emulsion.

Ideal for Severe Dry Eyes
Perfect for moderate to severe dry eye conditions.

Highly Praised Effectiveness
Customers love its soothing effect and non-irritating formula.
Key specs
- Formula:Preservative-free emulsion
- Usage:Moderate to severe dry eyes
- Preservatives:None
- Hydration:Moisturizes, lubricates, protects
- Dimensions:2.63 x 2.13 x 3 inches
8.6

Very Good

Our Rating

9.3
Moisturizing

8.9
Long life

8.4
worth the money

10 Best moisturizing eye drops without preservatives of 2025

1

Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)

9.3

8.7

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Biotrue Hydration Boost, Preservative-Free Eye Drops for Dry Eyes, Instantly Moisturizes, Rehydrates, Contact Lens Friendly, Refresh & Relieve Eye Irritation, 0.33 FL Oz (Pack of 2)

9.9

9.3

9.3

3

iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz Bottle

9.9

8.7

8.0

4

Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count

9.5

9.5

9.3

5

Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

9.9

9.3

8.9

6

Blink Boost Preservative-Free Lubricating Eye Drops, Eye Care Drops for Dry Eyes, Instant Moisture for Dry Irritated Eyes & Comfort Throughout the Day, Contact Lens Friendly, 10 mL

7

Biotrue Hydration Boost, Preservative-Free Eye Drops for Dry Eyes, Instantly Moisturizes, Rehydrates, Contact Lens Friendly, Refresh & Relieve Eye Irritation, 0.33 FL Oz (Pack of 1)

8

TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials

9.9

9.1

8.9

9

Soothe Preservative-Free Lubricant Eye Drops, Dry Eye Relief, Moisturizing, for Fast Relief & Gentle Enough for Sensitive Eyes and LASIK Dryness, Single-Use Vials, 30 Count

9.5

9.5

8.7

10

OCuSOFT Retaine MGD Ophthalmic Emulsion - Complete Dry Eye Relief - Soothes Red & Irritated Eyes - 30 Count Preservative-Free Single-Use Containers - 0.01 Fl Oz

9.3

8.9

8.4

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