10 Best mitochondrials of 2025

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Best Choice

1

Designs for Health
Designs for Health Mitochondria Energy Formula with Bio-PQQ - Mito-PQQ Rhodiola + 20mg PQQ (Pyrroloquinoline Quinone) Supplement - Supports Mitochondrial Biogenesis + Healthy Aging (60 Capsules)
Main highlights

Energy_and_Healthy_Aging_Support
Designed to support mitochondrial biogenesis, healthy aging, energy production, and protection from oxidative stress. Non-GMO, gluten-free, dairy-free, and soy-free.

Ideal_Use_Cases
Recommended for enhancing mitochondrial energy, brain health, and antioxidant support. Suitable for those seeking functional medicine practitioner-trusted supplements.

Most_Praised_Feature
Customers frequently commend the high quality and effectiveness of Designs for Health supplements, particularly for boosting energy and overall health.
9.8

Exceptional

Our Rating

9.9
simple to consume

9.9
worth the money

9.9
quality of ingredients
How do we rank?

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
Value for Money

2

Designs for Health
Designs for Health Mitochondrial NRG - Support Cellular Vitality + Metabolism - Mitochondria Energy Supplement with Alpha Lipoic Acid, Trans Resveratrol + Curcumin Powder (120 Vegan Capsules)
Main highlights

Energy and Metabolism Support
Features active B vitamins, CoQ10, and ALA for energy and mitochondrial health.

Ideal for Fatigue and Performance
Perfect for those with fatigue or seeking improved athletic performance.

Praised for Quick Effectiveness
Customers appreciate the fast-acting and noticeable energy boost.
9.7

Exceptional

Our Rating

9.9
Absorbency

9.9
quality of ingredients

9.9
Flavor
3

Life Extension
Life Extension Mitochondrial Energy Optimizer with PQQ – For Heart & Brain Health, Energy Management and Anti-Aging - Gluten-Free, Non-GMO, Vegetarian – 120 Capsules

28% Off
Main highlights

Cellular Energy Boost
Combines PQQ, carnosine, R-lipoic acid to enhance energy.

Ideal for Energy Management
Perfect for those seeking improved mental and physical energy.

Customer Praised Energy Boost
Highly effective in increasing energy levels throughout the day.
9.6

Exceptional

Our Rating

8.9
simple to consume

8.9
Flavor

8.7
worth the money
4

Resciency
2326 MG Mitochondrial Supplements with ATP, Vitamins, CoQ10 & PQQ, More Effective Than Creatine HMB & Nitric Oxide, Energy, Endurance, Strength, Recovery & Muscle, Organic, 240 Capsules
Main highlights

Comprehensive Energy Support
Combines ATP, CoQ10, PQQ, and vitamins for enhanced energy, endurance, and recovery.

Ideal for Active Lifestyles
Perfect for fitness enthusiasts and busy individuals needing sustained energy and muscle support.

Praised for Organic Ingredients
Customers love the natural energy boost from organic beetroot and maca root.
Key specs
- Form:Supplement
- Ingredients:ATP, CoQ10, PQQ, vitamins
- Benefits:Enhances energy and endurance
- Capsules:N/A
- Serving Size:N/A
9.4

Excellent

Our Rating
5

Bioclinic Naturals
Bioclinic Naturals Mitochondrial Formula 2.86 Ounce
Main highlights

High Energy Formula
Contains 300 mg of CoQ10 and 1500 mg of Acetyl-L-carnitine for enhanced energy.

Ideal for Active Lifestyles
Perfect for those seeking increased ATP levels without oxidative stress.

Praised for Energy Boost
Customers love the sustained energy and overall vitality boost.
9.2

Excellent

Our Rating

9.9
quality of ingredients

9.9
Efficient Energy Use

9.3
Flavor
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6

Peak Performance
Mitochondria Maximizer with CoQ10 and Active PQQ. Best Mitochondrial Support Supplement with MCT Oil. Natural Cellular Generator for Clean, Focused Energy 60 Vegetarian Capsules
Main highlights

Enhanced Cellular Energy
Peak Performance supplement supports mitochondrial function with PQQ and CoQ10, improving energy production and absorption.

Ideal for Chronic Pain Relief
Beneficial for those with joint inflammation or arthritis seeking reduced pain and increased mobility.

Boosts Mental Clarity
Customers praise improved alertness and focus, ideal for demanding work environments.
8.9

Very Good

Our Rating

9.9
worth the money

9.7
simple to consume

9.5
Absorbency
7

Life Extension
Life Extension Mitochondrial Basics with PQQ, L-Taurine, R-lipoic Acid, foundational Supplement for Cellular Energy Production, Brain and Heart Health, Gluten-Free, Non-GMO, Vegetarian, 30 Capsules
Main highlights

Supports Cellular Energy Production
Contains PQQ, R-lipoic acid, and taurine to enhance energy.

Ideal for Mitochondrial Support
Best for those with mitochondrial-related energy issues.

Praised for Overall Well-Being
Users report improved mental clarity and presence.
8.8

Very Good

Our Rating
8

CystoRebalance
CystoRebalance Urolithin A Supplement 2000MG - for Healthy Aging, Antioxidants and Mitochondrial Support - High Purity & Potency - 120 Softgels - 2 Month Supply
Main highlights

High Absorption and Potency
2000 mg of Urolithin A in easy-to-swallow softgels for enhanced absorption and effectiveness.

Ideal for Healthy Aging
Promotes overall wellness and mitochondrial support, perfect for those seeking antioxidants and longevity benefits.

Customer Praise for Convenience
Users love the convenient softgel form and the easy daily dosage.
Key specs
- Form:Softgel
- Ingredients:Urolithin A
- Benefits:Promotes Overall Wellness
- Capsules:60 Day Supply
- Serving Size:2 Softgels
8.5

Good

Our Rating
9

Life Extension
Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support, ubiquinol CoQ10, shilajit, potent heart health & cellular energy production support, ultra-absorbable, gluten-free, 60 softgel
Main highlights

Heart and Cellular Energy Support
Combines ubiquinol CoQ10 and shilajit for enhanced heart health and energy.

Ideal for High-Energy Organs
Suitable for individuals seeking to boost brain, liver, and kidney energy.

Consistently High Quality
Praised for reliable quality across Life Extension's product range.
8.4

Good

Our Rating

9.7
simple to consume

9.1
Absorbency

9.1
worth the money
10

Life Extension
Life Extension PQQ Caps – Pyrroloquinoline Quinone, 10 mg – Promotes The Growth of New Mitochondria, ATP, Energy Support – Gluten-Free, Non-GMO, Vegetarian – 30 Capsules

50% Off
Main highlights

Promotes Mitochondrial Growth
PQQ supports new mitochondrial growth, boosting cellular energy.

Ideal for Aging Adults
Useful for older individuals needing cognitive and energy support.

Praised for Energy Boost
Customers report increased energy and reduced fatigue.
8.1

Good

Our Rating

9.9
quality of ingredients

9.3
Efficient Energy Use

8.0
worth the money

10 Best mitochondrials of 2025

1

Designs for Health Mitochondria Energy Formula with Bio-PQQ - Mito-PQQ Rhodiola + 20mg PQQ (Pyrroloquinoline Quinone) Supplement - Supports Mitochondrial Biogenesis + Healthy Aging (60 Capsules)

9.9

9.9

9.9

2

Designs for Health Mitochondrial NRG - Support Cellular Vitality + Metabolism - Mitochondria Energy Supplement with Alpha Lipoic Acid, Trans Resveratrol + Curcumin Powder (120 Vegan Capsules)

9.9

9.9

9.9

3

Life Extension Mitochondrial Energy Optimizer with PQQ – For Heart & Brain Health, Energy Management and Anti-Aging - Gluten-Free, Non-GMO, Vegetarian – 120 Capsules

8.9

8.9

8.7

4

2326 MG Mitochondrial Supplements with ATP, Vitamins, CoQ10 & PQQ, More Effective Than Creatine HMB & Nitric Oxide, Energy, Endurance, Strength, Recovery & Muscle, Organic, 240 Capsules

5

Bioclinic Naturals Mitochondrial Formula 2.86 Ounce

9.9

9.9

9.3

6

Mitochondria Maximizer with CoQ10 and Active PQQ. Best Mitochondrial Support Supplement with MCT Oil. Natural Cellular Generator for Clean, Focused Energy 60 Vegetarian Capsules

9.9

9.7

9.5

7

Life Extension Mitochondrial Basics with PQQ, L-Taurine, R-lipoic Acid, foundational Supplement for Cellular Energy Production, Brain and Heart Health, Gluten-Free, Non-GMO, Vegetarian, 30 Capsules

8

CystoRebalance Urolithin A Supplement 2000MG - for Healthy Aging, Antioxidants and Mitochondrial Support - High Purity & Potency - 120 Softgels - 2 Month Supply

9

Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support, ubiquinol CoQ10, shilajit, potent heart health & cellular energy production support, ultra-absorbable, gluten-free, 60 softgel

9.7

9.1

9.1

10

Life Extension PQQ Caps – Pyrroloquinoline Quinone, 10 mg – Promotes The Growth of New Mitochondria, ATP, Energy Support – Gluten-Free, Non-GMO, Vegetarian – 30 Capsules

9.9

9.3

8.0

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