10 Best migraine supplements of 2025

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Best Choice

1

MigreLief

MigreLief Original Formula Triple Therapy with Puracol, 60 Count (Pack of 3)
9.6

Exceptional

Our Rating
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Value for Money

2

Vita Sciences
Vita Sciences Migravent Migraine Relief Supplement w/Vitamin B2, Riboflavin, Magnesium, Coenzyme CoQ10, PA-Free Butterbur, Bioperine, Premium Herbal Extracts 60 Count
Main highlights

Key Ingredients and Benefits
Migravent contains Vitamin B2, Magnesium, CoQ10, and PA-Free Butterbur for natural migraine relief and brain health.

Ideal Use for Migraine Sufferers
Perfect for those seeking a natural, caffeine-free solution to reduce migraine frequency and severity.

Customer Praise for Effectiveness
Many users report a significant decrease in migraine frequency and severity after regular use.
Key specs
- Gluten-Free:Yes
- Form:Capsules
- Ingredients:Vitamin B2, Magnesium, Butterbur
- Non-GMO:Yes
- Benefits:Migraine relief, brain health
9.5

Excellent

Our Rating

9.1
simple to consume

8.9
Flavor

8.2
worth the money
3

MigreLief
MigreLief Original Triple Therapy with Puracol - Nutritional Support for Migraine Sufferers - 60 Caplets/1 Month Supply
Main highlights

Effective Nutritional Support
MigreLief provides dual patented nutritional support for migraine sufferers with a unique combination of Magnesium, Riboflavin, and Puracol Feverfew.

Recommended for Migraine Prevention
Ideal for adults and teens seeking consistent migraine prevention with a safe, non-GMO, vegetarian formula.

Improved Quality of Life
Users report significant reduction in migraine frequency and severity, enhancing daily life quality.
9.3

Excellent

Our Rating

8.9
worth the money

8.4
simple to consume

8.2
Flavor
4

C Calthorvitana

C Calthorvitana Migraine Relief Supplement – Liposomal Riboflavin, Vitamin B2 B6 & B12, Magnesium, CoQ10, L-Theanine, PA-Free Butterbur & Feverfew – Natural Head & Nerve – 60 Softgels
9.2

Excellent

Our Rating
5

Alafia Naturals
Migraine Gummy – Headache and Migraine Relief Supplement with Magnesium Glycinate, CoQ10, Feverfew, Butterbur, and Riboflavin – 60 Gummies
Main highlights

Natural Ingredients and Benefits
Combines Magnesium Glycinate, Vitamin B2, CoQ10, Butterbur, Feverfew for migraine relief.

Daily Use for Prevention
Ideal for daily use to reduce frequency and severity of migraines.

Taste and Ease of Use
Orange-flavored gummies praised for taste and easy consumption.
Key specs
- Form:Gummy
- Usage Instructions:Daily doses for relief
- Dietary Restrictions:Vegan, non-GMO
- Flavor:Orange
- Elemental Magnesium:Magnesium Glycinate
9.1

Excellent

Our Rating

9.7
Flavor

9.5
simple to consume

9.1
pain management
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6

Quantum Health
Quantum Health MigShield Magnesium Supplement with Riboflavin & CoQ10 Helps Promote Proper Function of Brain Heart & Muscles Daily Nutritional Essentials for Women & Men - 60 Tablets

26% Off
Main highlights

Effective Magnesium Formula
Combines magnesium oxide and citrate, riboflavin, and CoQ10 for brain, heart, and muscle support.

Ideal for Migraine Prevention
Beneficial for individuals seeking to prevent migraines with a natural supplement.

Praised for Size and Composition
Smaller pill size and comprehensive formulation praised by users.
9.0

Excellent

Our Rating

9.9
simple to consume

9.7
quality of ingredients

9.3
pain management
7

Naticura
Migratone Migraine Relief - Natural Headache Relief Vitamin - Migraine Supplement with PA - Free Butterbur, Magnesium, Vitamin B2 B6 and B12, Microactive CoQ10 and Feverfew - Migraine Clinic's Choice

15% Off
Main highlights

Powerful Ingredients for Headache Relief
Migratone combines PA-free Butterbur, Ashwagandha, Feverfew, Riboflavin, and Magnesium for effective migraine relief.

Ideal for Migraine Sufferers
Best for individuals seeking natural alternatives to reduce migraine frequency and intensity.

Customer Praised Ingredient Combination
Highly praised for its effective blend of natural ingredients that help manage migraines.
Key specs
- Form:Capsules
- Use:Headache relief
- Active Ingredient:Butterbur, Ashwagandha
- Features:No gluten, dairy, GMOs
- Material:Vegan, plant-based
8.9

Very Good

Our Rating

9.3
simple to consume

9.3
worth the money

8.9
Flavor
8

Carlyle

Carlyle Feverfew Capsules 380mg | 180 Count | Traditional Herb Extract | Non-GMO, Gluten Free
8.7

Very Good

Our Rating
9

Family Tree Remedies
Preventa Migraine Relief Supplement – PA-Free Butterbur, Magnesium, Riboflavin, Feverfew – Daily Headache Prevention – 60 Capsules
Main highlights

Natural Ingredients for Migraine Relief
Utilizes high-grade natural ingredients like butterbur, feverfew, riboflavin, and magnesium.

Ideal for Chronic Headache Sufferers
Designed for those with migraines and chronic daily headaches.

Effective Pain Reduction
Customers report significant pain reduction and fewer migraines over time.
8.6

Very Good

Our Rating

9.9
quality of ingredients

9.7
pain management

8.0
worth the money
10

MigreLief

MigreLief® Nutritional Support Kit for Migraine & Headache Sufferers Original Daily Formula Now Fast-Acting/As-Needed Formula - Supplement Bundle Pack - 1 Month Supply
8.5

Good

Our Rating

10 Best migraine supplements of 2025

1

MigreLief Original Formula Triple Therapy with Puracol, 60 Count (Pack of 3)

How do we rank?

How do we rank?

Analyzing top stores

2

Vita Sciences Migravent Migraine Relief Supplement w/Vitamin B2, Riboflavin, Magnesium, Coenzyme CoQ10, PA-Free Butterbur, Bioperine, Premium Herbal Extracts 60 Count

9.1

8.9

8.2

3

MigreLief Original Triple Therapy with Puracol - Nutritional Support for Migraine Sufferers - 60 Caplets/1 Month Supply

8.9

8.4

8.2

4

C Calthorvitana Migraine Relief Supplement – Liposomal Riboflavin, Vitamin B2 B6 & B12, Magnesium, CoQ10, L-Theanine, PA-Free Butterbur & Feverfew – Natural Head & Nerve – 60 Softgels

5

Migraine Gummy – Headache and Migraine Relief Supplement with Magnesium Glycinate, CoQ10, Feverfew, Butterbur, and Riboflavin – 60 Gummies

9.7

9.5

9.1

6

Quantum Health MigShield Magnesium Supplement with Riboflavin & CoQ10 Helps Promote Proper Function of Brain Heart & Muscles Daily Nutritional Essentials for Women & Men - 60 Tablets

9.9

9.7

9.3

7

Migratone Migraine Relief - Natural Headache Relief Vitamin - Migraine Supplement with PA - Free Butterbur, Magnesium, Vitamin B2 B6 and B12, Microactive CoQ10 and Feverfew - Migraine Clinic's Choice

9.3

9.3

8.9

8

Carlyle Feverfew Capsules 380mg | 180 Count | Traditional Herb Extract | Non-GMO, Gluten Free

9

Preventa Migraine Relief Supplement – PA-Free Butterbur, Magnesium, Riboflavin, Feverfew – Daily Headache Prevention – 60 Capsules

9.9

9.7

8.0

10

MigreLief® Nutritional Support Kit for Migraine & Headache Sufferers Original Daily Formula Now Fast-Acting/As-Needed Formula - Supplement Bundle Pack - 1 Month Supply

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