10 Best methylated multivitamins of 2025

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1

Pure Therapro Rx
Methyl Multi Without Iron Methylated Multivitamin for Men & Women, 120-Day Supply | Methyl B12 & Methylfolate (5-MTHF) for MTHFR Support | Pharma Grade Multivitamin & Multimineral For Health, 240 Caps
Main highlights

Comprehensive Wellness Support
Methyl Multi without Iron is a meticulously-researched multivitamin promoting cognitive function and detoxification with high-quality ingredients.

Ideal for MTHFR Mutations
Perfect for individuals with MTHFR mutations, enhancing vitamin absorption and supporting metabolism and energy release.

Customer-Praised Effectiveness
Customers appreciate the improvement in B12 levels and reduced neuropathic symptoms, highlighting its effectiveness.
9.8

Exceptional

Our Rating

9.9
quality of ingredients

9.5
worth the money

9.5
Absorbency
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Value for Money

2

10X Health System
10X Health Optimize Methylated Multivitamin for Men & Women - 34 in 1 Formula with 800 mcg of Vitamin B12, Vitamin E, 5-MTHF, B Complex, NAC, Magnesium & Zinc Multivitamins - 90 Capsules
Main highlights

Comprehensive Nutritional Support
10x Optimize provides a multivitamin and mineral formula addressing genetic methylation deficits for optimal health.

Efficient Supplementation
Best used for reducing overall supplement intake while maintaining nutritional balance.

Enhanced Absorption and Well-being
Praised for methylated nutrients improving absorption, reducing anxiety, and boosting sleep quality.
Key specs
- B-Vitamins:Includes B12, B2, B6
- Vitamin D:N/A
- Zinc:Yes
- Calcium:N/A
- Vitamin E:N/A
9.5

Excellent

Our Rating
3

Micro Ingredients
Micro Ingredients Pure Methylated Multivitamin, 240 Capsules | 11-in-1 Formula with Vitamins C, D, B12, Folate, Magnesium, Zinc & More | Supports Daily Wellness & Immune Health | Filler Free, Non-GMO
Main highlights

High Absorption Bioactive Form
This multivitamin features 19 essential nutrients in highly absorbable forms, ensuring effective nutrient uptake and utilization.

Comprehensive Health Support
Ideal for men and women seeking energy, heart, immune, and brain health support through a complete multivitamin solution.

Filler-Free Formula
Customers appreciate the pure, active ingredients without fillers, enhancing the supplement's effectiveness and safety.
Key specs
- Form:Capsuled formula
- Ingredients:Methylated Multivitamin Complex
- Non-GMO:Yes
- Benefits:Energy, heart, immune support
- Serving Size:240 capsules
9.4

Excellent

Our Rating
4

Double Wood Supplements
Methylated Multivitamin (Methylated and Activated Vitamins Only - Methylated B Complex with Trimethylglycine (TMG) and Methylfolate)(Non-GMO, Gluten Free MTHFR Supplement) 120 Capsules by Double Wood
Main highlights

Methylated and Activated Vitamins
Contains methylated forms of vitamins for improved bioavailability and absorption.

Ideal for MTHFR Gene Mutation
Perfect for individuals needing methylated vitamins due to MTHFR mutation.

Praised for Bioavailability
Customers appreciate the bioavailability of pre-converted B vitamins.
Key specs
- B-Vitamins:Methylated B Complex
- Vitamin D:Included
- Zinc:N/A
- Calcium:Included
- Vitamin E:N/A
9.3

Excellent

Our Rating
5

envitamin
envitamin Methylated Multivitamin Multimineral Complex L Methylfolate
Main highlights

Comprehensive Nutritional Support
Includes methylated B12, 5-MTHF, inositol, and lycopene for enhanced absorption.

Ideal for Active Lifestyles
Perfect for athletes and active individuals seeking improved recovery and energy.

Praised for Energy Boost
Customers appreciate the noticeable increase in energy and overall wellness.
9.2

Excellent

Our Rating
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6

Igennus Healthcare Nutrition
Igennus High Strength Methylated Men's Multivitamin, All-Day Nutrient Delivery, Clean MTHFR Supplement with Active B12 and Methylfolate, 21 Highly Bioavailable Nutrients, Non-GMO & Halal, 60 Tablets
Main highlights

High-Potency Nutrients
22 essential nutrients with bioactive B-complex, chelated minerals, and antioxidants for men's health.

Daily Energy and Immunity
Ideal for boosting daily energy and immune support with methylated B-vitamins and vitamin D3.

Bioavailable Vitamins Praised
Customers praise bioavailable forms of vitamins, especially methylated B-vitamins and methylfolate.
Key specs
- B-Vitamins:active B-complex
- Vitamin D:D3
- Zinc:high absorption zinc
- Calcium:N/A
- Vitamin E:N/A
9.1

Excellent

Our Rating
7

NUTRAHARMONY
Methylated Multivitamin - B-Complex with Methylfolate & B12 - for Men & Women - 9-in-1 MTHFR Supplement with TMG - for Energy, Brain & Mood - Vegan, Lab Tested - Made in USA - 120 Capsules, One/Day
Main highlights

Essential Vitamins for Methylation
Contains 9 vital vitamins including methylated B complex for daily wellness.

Daily Energy and Cognitive Support
Ideal for boosting energy, enhancing focus, and maintaining mood balance.

Customer Favorite for Energy Boost
Praised for its effective energy and metabolism support.
Key specs
- B-Vitamins:B2, B6, B9, B12
- Vitamin D:D3
- Zinc:N/A
- Calcium:N/A
- Vitamin E:Yes
9.0

Excellent

Our Rating
8

Nutricost

Nutricost Methylated Multivitamin 120 Capsules, 60 Servings - 23 Vitamin & Minerals Per Serving
8.9

Very Good

Our Rating
9

Pure Encapsulations
Pure Encapsulations O.N.E. Multivitamin - Once Daily Multivitamin with Antioxidant Complex Metafolin, CoQ10, and Lutein to Support Vision, Cognitive Function, and Cellular Health* - 60 Capsules
Main highlights

Comprehensive Nutrient Support
Includes vitamins A, B, C, D, E, CoQ10, L-5-MTHF, and ALA for antioxidant and cognitive support.

Ideal for Energy Boost
Best used for enhancing energy levels and cognitive function in active individuals.

Energy Enhancement Praised
Customers frequently commend the multivitamin for significantly boosting energy and improving daily vitality.
Key specs
- Form:Capsules
- Ingredients:Vitamins A, B, C, D, E
- Non-GMO:Yes
- Benefits:Cognitive support, wellness
- Serving Size:Once-daily capsules
8.6

Very Good

Our Rating

9.1
simple to consume

9.1
worth the money

9.1
quality of ingredients
10

Inessa
Inessa Methylated Multivitamin for Men and Women - Advanced Natural Daily Mens Multivitamins with CoQ10 100mg, Vitamins D3, K2, A, B Complex Vitamins, Folic Acid & Zinc - 60 Vegan Tablets
Main highlights

Comprehensive Wellness Support
This multivitamin includes 25 bioavailable ingredients for optimal health.

Ideal for Busy Lifestyles
One-a-day tablet simplifies daily wellness for men and women.

Highly Praised Ingredient List
Customers appreciate the extensive and clean ingredient profile.
8.4

Good

Our Rating

9.9
worth the money

9.3
quality of ingredients

8.7
simple to consume

10 Best methylated multivitamins of 2025

1

Methyl Multi Without Iron Methylated Multivitamin for Men & Women, 120-Day Supply | Methyl B12 & Methylfolate (5-MTHF) for MTHFR Support | Pharma Grade Multivitamin & Multimineral For Health, 240 Caps

9.9

9.5

9.5

How do we rank?

How do we rank?

Analyzing top stores

2

10X Health Optimize Methylated Multivitamin for Men & Women - 34 in 1 Formula with 800 mcg of Vitamin B12, Vitamin E, 5-MTHF, B Complex, NAC, Magnesium & Zinc Multivitamins - 90 Capsules

3

Micro Ingredients Pure Methylated Multivitamin, 240 Capsules | 11-in-1 Formula with Vitamins C, D, B12, Folate, Magnesium, Zinc & More | Supports Daily Wellness & Immune Health | Filler Free, Non-GMO

4

Methylated Multivitamin (Methylated and Activated Vitamins Only - Methylated B Complex with Trimethylglycine (TMG) and Methylfolate)(Non-GMO, Gluten Free MTHFR Supplement) 120 Capsules by Double Wood

5

envitamin Methylated Multivitamin Multimineral Complex L Methylfolate

6

Igennus High Strength Methylated Men's Multivitamin, All-Day Nutrient Delivery, Clean MTHFR Supplement with Active B12 and Methylfolate, 21 Highly Bioavailable Nutrients, Non-GMO & Halal, 60 Tablets

7

Methylated Multivitamin - B-Complex with Methylfolate & B12 - for Men & Women - 9-in-1 MTHFR Supplement with TMG - for Energy, Brain & Mood - Vegan, Lab Tested - Made in USA - 120 Capsules, One/Day

8

Nutricost Methylated Multivitamin 120 Capsules, 60 Servings - 23 Vitamin & Minerals Per Serving

9

Pure Encapsulations O.N.E. Multivitamin - Once Daily Multivitamin with Antioxidant Complex Metafolin, CoQ10, and Lutein to Support Vision, Cognitive Function, and Cellular Health* - 60 Capsules

9.1

9.1

9.1

10

Inessa Methylated Multivitamin for Men and Women - Advanced Natural Daily Mens Multivitamins with CoQ10 100mg, Vitamins D3, K2, A, B Complex Vitamins, Folic Acid & Zinc - 60 Vegan Tablets

9.9

9.3

8.7

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