10 Best methylated b complexes of 2025

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1

Pure Therapro Rx
Pure TheraPro Rx Methylated B Complex Vitamins Made in USA, 4 Month Supply | Methyl B Complete Quatrefolic 5-MTHF Folate, B12 Methylcobalamin, TMG Trimethylglycine, Methylfolate | Pharm Grade
Main highlights

Advanced Methylation Support
Features active B vitamins including Folate as Quatrefolic and Methylcobalamin for enhanced bioavailability and energy production.

Ideal for Allergen-Sensitive Users
Free from gluten, soy, corn, and other common allergens, perfect for sensitive individuals.

Boosts Energy and Focus
Praised for significantly increasing energy levels and mental clarity according to customer reviews.
9.9

Exceptional

Our Rating

9.5
simple to consume

9.5
quality of ingredients

9.3
worth the money
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Value for Money

2

Pure Encapsulations
Pure Encapsulations B-Complex Plus - B Vitamins Supplement to Support Neurological Health, Cardiovascular Health, Energy Levels & Nervous System Support* - with Vitamin B12 & More - 120 Capsules
Main highlights

Nervous_System_and_Cardiovascular_Support
Supports nervous and cardiovascular systems, promoting healthy nerve, blood cells, hair, skin, and nails.

Ideal_for_Neurological_and_Cognitive_Health
Perfect for those needing cognitive and neurological health support, including memory and energy.

Customer_Praised_Professional_Recommendation
Frequently recommended by healthcare professionals and praised for its effectiveness.
Key specs
- Form:Capsule
- Formulation:Methylated Folate, B12
- Ingredients:B vitamins, Metafolin
- Vitamin B Complex:Pure Encapsulations
- Support Type:Nervous, Cardiovascular
9.6

Exceptional

Our Rating

9.7
simple to consume

9.5
quality of ingredients

9.3
Absorbency
3

Igennus Healthcare Nutrition
Igennus Super B-Complex Methylated B Vitamins, Sustained Release, Clean Label, MTHFR Supplement with Methylfolate & B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets

20% Off
Main highlights

High Absorption B Vitamins
Features methylated forms like methylfolate & methylcobalamin for superior absorption and efficacy.

Ideal for Energy and Heart Health
Supports energy metabolism, immune function, and heart health with MTHFR-friendly ingredients.

Praised for Clean Ingredients
Customers appreciate the absence of fillers and the vegan, hypoallergenic formula.
9.5

Excellent

Our Rating

9.7
simple to consume

9.7
quality of ingredients

9.5
worth the money
4

Micro Ingredients
Pure Methylated B Complex for Women & Men | 240 Capsules with High Absorption Vitamin C | 11-in-1 with Vitamins B12, Thiamin, Folate + Inositol, Choline & More | Only Active Ingredients | Filler Free
Main highlights

11-in-1 Formula with Fat-Soluble Vitamin C
Combines 11 essential nutrients, including methylated B vitamins and fat-soluble vitamin C, for comprehensive health support.

Ideal for Energy and Brain Health
Perfect for those seeking enhanced energy levels and cognitive function through high-quality B vitamins and antioxidants.

Praised for High Absorption and Purity
Customers appreciate the product's high absorption rate and the absence of fillers, ensuring a pure and effective supplement.
Key specs
- Form:Capsules
- Formulation:Methylated vitamins with C
- Ingredients:Thiamin, riboflavin, niacin
- Vitamin B Complex:Methylated B Complex
- Support Type:Energy, cellular, heart
9.4

Excellent

Our Rating
5

Igennus Healthcare Nutrition
Igennus Super B-Complex Methylated B-Vitamins, MTHFR Supplement with Methylfolate & B12 Methylcobalamin, High Bioavailability & Potency, Vegan, Lab Verified, 180 Small Tablets

16% Off
Main highlights

Key Features and Benefits
High-strength, super absorbable B complex with methylated forms for instant use, sustained release for all-day support, and pure, clean ingredients.

Ideal Use Cases
Perfect for those needing intensive support for energy metabolism, immune health, homocysteine regulation, and MTHFR gene mutation carriers.

Customer Reviews Summary
Most praised for significantly improving energy levels and overall well-being, with many appreciating the hypoallergenic, vegan-friendly formula.
9.3

Excellent

Our Rating

9.7
simple to consume

9.5
worth the money

9.3
Absorbency
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6

Triquetra Health
BioActive Vitamin B Complex - Blood Stream Ready, Methylated B Complex - Featuring Methylfolate, 3 BioActive Forms of B12, BenfoPure® B1 & Pantesin® B5 - 12 B Vitamins in Clinical Doses - 60 Servings
Main highlights

Max Absorption B Vitamins
Active and methylated forms ensure faster energy and vitality.

Ideal for Energy Boost
Perfect for enhancing metabolism and overall vitality.

Highly Praised Absorption
Customers love the effective absorption and energy boost.
Key specs
- Form:Capsule
- Formulation:Methylated forms
- Ingredients:Methyl B12, L-Methylfolate
- Vitamin B Complex:Bioactive B12 Complex
- Support Type:Energy, metabolism, vitality
9.2

Excellent

Our Rating
7

THORNE
THORNE Basic B-Complex - Tissue-Ready Vitamin B Complex Supplement with Choline - Supports Cellular Energy Production, Brain Health & Red Blood Cell Formation* - Gluten-Free, Dairy-Free - 60 Capsules
Main highlights

Optimal Nervous System Support
Promotes healthy nerve cells and optimal nervous system function.

Ideal for Energy Boost
Perfect for those needing enhanced cellular energy and vitality.

Praised for Balanced B6
Customers love the balanced B6 for avoiding toxicity.
Key specs
- Form:Capsule
- Formulation:Eight B vitamins, choline
- Ingredients:B vitamins, choline
- Vitamin B Complex:Thorne Research
- Support Type:Nervous System, Cellular Energy
9.1

Excellent

Our Rating

9.3
simple to consume

9.1
worth the money

8.7
Flavor
8

PrimeMD

Methylated B Complex with Methylfolate and B12 Methylcobalamin 1000 mcg - Methylated Multivitamin for Energy, Brain Function, and Wellness - Vitamin B Complex for Men & Women (90 Servings) (Pack of 1)
9.0

Excellent

Our Rating
9

Life Extension
Life Extension BioActive Complete B-Complex, Heart, Brain and Nerve Support, Healthy Energy, Metabolism, Complete B Complex, 60 Vegetarian Capsules
Main highlights

Heart and Brain Health Support
BioActive Complete B-Complex nourishes heart and brain health with a full spectrum of B vitamins.

Ideal for Energy and Metabolism
Perfect for boosting energy and supporting metabolism in daily routines.

Praised for Energy Boost
Customers appreciate the noticeable energy increase after taking the supplement.
Key specs
- Form:Capsule
- Formulation:Easy-to-absorb
- Ingredients:Full spectrum vitamin B
- Vitamin B Complex:BioActive Complete B-Complex
- Support Type:Heart & brain health
8.9

Very Good

Our Rating

8.9
simple to consume

8.9
worth the money

8.2
Flavor
10

Double Wood Supplements
Methylated Multivitamin (Methylated and Activated Vitamins Only - Methylated B Complex with Trimethylglycine (TMG) and Methylfolate)(Non-GMO, Gluten Free MTHFR Supplement) 120 Capsules by Double Wood
Main highlights

Methylated and Activated Vitamins
Contains methylated forms of vitamins for improved bioavailability and absorption.

Ideal for MTHFR Gene Mutation
Perfect for individuals needing methylated vitamins due to MTHFR mutation.

Praised for Bioavailability
Customers appreciate the bioavailability of pre-converted B vitamins.
Key specs
- Calcium:Included
- Vitamin D:Included
- B-Vitamins:Methylated B Complex
- Vitamin A:N/A
- Vitamin E:N/A
8.8

Very Good

Our Rating

10 Best methylated b complexes of 2025

1

Pure TheraPro Rx Methylated B Complex Vitamins Made in USA, 4 Month Supply | Methyl B Complete Quatrefolic 5-MTHF Folate, B12 Methylcobalamin, TMG Trimethylglycine, Methylfolate | Pharm Grade

9.5

9.5

9.3

How do we rank?

How do we rank?

Analyzing top stores

2

Pure Encapsulations B-Complex Plus - B Vitamins Supplement to Support Neurological Health, Cardiovascular Health, Energy Levels & Nervous System Support* - with Vitamin B12 & More - 120 Capsules

9.7

9.5

9.3

3

Igennus Super B-Complex Methylated B Vitamins, Sustained Release, Clean Label, MTHFR Supplement with Methylfolate & B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets

9.7

9.7

9.5

4

Pure Methylated B Complex for Women & Men | 240 Capsules with High Absorption Vitamin C | 11-in-1 with Vitamins B12, Thiamin, Folate + Inositol, Choline & More | Only Active Ingredients | Filler Free

5

Igennus Super B-Complex Methylated B-Vitamins, MTHFR Supplement with Methylfolate & B12 Methylcobalamin, High Bioavailability & Potency, Vegan, Lab Verified, 180 Small Tablets

9.7

9.5

9.3

6

BioActive Vitamin B Complex - Blood Stream Ready, Methylated B Complex - Featuring Methylfolate, 3 BioActive Forms of B12, BenfoPure® B1 & Pantesin® B5 - 12 B Vitamins in Clinical Doses - 60 Servings

7

THORNE Basic B-Complex - Tissue-Ready Vitamin B Complex Supplement with Choline - Supports Cellular Energy Production, Brain Health & Red Blood Cell Formation* - Gluten-Free, Dairy-Free - 60 Capsules

9.3

9.1

8.7

8

Methylated B Complex with Methylfolate and B12 Methylcobalamin 1000 mcg - Methylated Multivitamin for Energy, Brain Function, and Wellness - Vitamin B Complex for Men & Women (90 Servings) (Pack of 1)

9

Life Extension BioActive Complete B-Complex, Heart, Brain and Nerve Support, Healthy Energy, Metabolism, Complete B Complex, 60 Vegetarian Capsules

8.9

8.9

8.2

10

Methylated Multivitamin (Methylated and Activated Vitamins Only - Methylated B Complex with Trimethylglycine (TMG) and Methylfolate)(Non-GMO, Gluten Free MTHFR Supplement) 120 Capsules by Double Wood

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