November 4, 2025

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10 Best lysine pills of 2025

Save up to 40% off

Best Choice

1

Quantum Health
Quantum Health Super Lysine+ / Advanced Formula Lysine+ Immune Support with Vitamin C, Echinacea, Licorice, Propolis, Odorless Garlic (180 Tablets), Packaging may vary
Main highlights

Immune Support and Lip Health
SuperLysine+ combines L-Lysine, Vitamin C, and Echinacea for enhanced immune and lip health support.

Ideal for Cold Sore Prevention
Perfect for those seeking to prevent and manage cold sore outbreaks effectively.

Customer Praised Cold Sore Relief
Highly praised for stopping cold sores quickly and effectively.
Key specs
- Form:Tablets
- Quality:Award-winning formula
- Functions:Immune support, lip health
- Dosage:60-day supply
- Certification:N/A
9.8

Exceptional

Our Rating

9.3
quality of ingredients

9.1
Absorbency

8.9
simple to consume
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

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Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Solgar
Solgar L-Lysine 1000 mg, 250 Tablets - Enhanced Absorption and Assimilation - Promotes Integrity of Skin and Lips - Collagen Support - Amino Acids - Non-GMO, Vegan, Gluten Free - 250 Servings

21% Off
Main highlights

Collagen Support and Skin Integrity
L-Lysine aids collagen production, enhancing skin and lip health.

Versatile Health Applications
Ideal for skin health, cold sore prevention, and immune support.

Highly Praised Skin Benefits
Customers report improved skin clarity and reduced blemishes.
9.7

Exceptional

Our Rating

9.7
quality of ingredients

8.9
Absorbency

8.7
Flavor
3

Nature Made
Nature Made L-Lysine 1000 mg, Dietary Supplement, 60 Tablets, 60 Day Supply

40% Off
Main highlights

Protein Synthesis Support
Nature Made L-Lysine 1000 mg tablets aid in protein synthesis with essential amino acids.

Ideal for Cold Sores
Effective in reducing cold sore healing time and preventing outbreaks.

Customer Praise for Effectiveness
Users appreciate its effectiveness in managing cold sores and overall quality.
9.4

Excellent

Our Rating

8.4
worth the money

8.0
Flavor

8.0
simple to consume
4

NOW Foods
NOW Foods Supplements, (L-Lysine Hydrochloride) 1,000 mg, Double Strength, Amino Acid, 100 Tablets

34% Off
Main highlights

Essential Amino Acid Support
L-Lysine is crucial for collagen synthesis and protein maintenance.

Immune System Boost
Ideal for cold/flu season and preventing viral outbreaks.

Customer Praised Effectiveness
Highly effective in reducing cold sore and shingles severity.
9.3

Excellent

Our Rating

9.5
worth the money

8.9
Absorbency

8.2
Flavor
5

Bronson
Bronson L-Lysine Defense Immune Support Complex 1500 MG L-Lysine Plus Olive Leaf, Garlic, Vitamin C and Zinc - Non-GMO, 90 Vegetarian Capsules
Main highlights

Comprehensive Immune Support
Combines L-Lysine with Olive Leaf, Garlic, Vitamin C, and Zinc for enhanced immune health.

Ideal for Immune Boosting
Perfect for individuals seeking to maintain a healthy immune system.

Easy to Swallow Capsules
Praised for smooth, easy-to-swallow capsules enhancing user experience.
9.1

Excellent

Our Rating

9.5
simple to consume

9.3
worth the money

9.1
Flavor
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6

Pure Encapsulations
Pure Encapsulations L-Lysine - Essential Amino Acid Supplement for Immune Support & Gum, Lip Health* - with L-Lysine HCl - 90 Capsules
Main highlights

Essential Amino Acid Support
L-Lysine aids immune function and natural defenses, vital for health.

Cold Sores and Shingles Relief
Ideal for managing cold sores and shingles symptoms effectively.

Praised for Purity
Customers appreciate its purity and absence of fillers.
Key specs
- Form:Capsules
- Quality:Premium ingredients
- Functions:Immune support
- Dosage:N/A
- Certification:Free from allergens
8.8

Very Good

Our Rating

9.9
simple to consume

9.7
worth the money

9.7
Flavor
7

NOW Foods
NOW Foods Supplements, L-Lysine (L-Lysine Monohydrochloride) 500 mg, Amino Acid, 100 Veg Capsules

33% Off
Main highlights

Supports Collagen and Immune Health
L-Lysine aids collagen synthesis and supports immune and cardiovascular health.

Versatile Dosage for Various Needs
Ideal for athletes, vegans, and those needing adjustable supplementation.

Effective Cold Sore Management
Praised for reducing cold sore duration and severity.
8.7

Very Good

Our Rating

9.5
worth the money

9.1
Flavor

8.9
simple to consume
8

Best Naturals
Best Naturals L-Lysine 1000mg 180 Tablets - Double Strength Lysine for stronger immune health & cold sores

16% Off
Main highlights

Key Features
1000 mg L-Lysine HCL per tablet, 180 count, non-GMO, gluten-free, made in USA, GMP compliant, FDA registered, no artificial additives.

Ideal Use Cases
Perfect for those seeking immune support, skin health, and improved calcium absorption without allergens or artificial ingredients.

Customer Reviews
Highly praised for purity and effectiveness in supporting immune health and addressing skin issues, with noticeable results.
Key specs
- Form:Tablet
- Quality:3rd Party Lab Tested
- Functions:N/A
- Dosage:1000 mg
- Certification:GMP Compliant
8.6

Very Good

Our Rating

9.5
worth the money

8.7
simple to consume

8.7
Flavor
9

Nature's Bounty

Nature's Bounty L-Lysine, 1000mg, 60 Tablets
8.5

Good

Our Rating
10

THORNE
THORNE - Lysine - Essential Amino Acid for Skin Health, Energy Production, and Immune Function* - 500 mg - 60 Capsules
Main highlights

Promotes Collagen Formation
Supports skin health, immune function, and energy production with 500 mg of lysine per capsule.

Ideal for Skin and Immune Support
Best used for maintaining healthy skin, gums, and immune defenses.

Highly Rated for Cold Sore Relief
Praised for effectively minimizing cold sore outbreaks and aiding post-surgery recovery.
8.2

Good

Our Rating

9.9
worth the money

9.7
simple to consume

9.5
Flavor

10 Best lysine pills of 2025

1

Quantum Health Super Lysine+ / Advanced Formula Lysine+ Immune Support with Vitamin C, Echinacea, Licorice, Propolis, Odorless Garlic (180 Tablets), Packaging may vary

9.3

9.1

8.9

How do we rank?

How do we rank?

Analyzing top stores

2

Solgar L-Lysine 1000 mg, 250 Tablets - Enhanced Absorption and Assimilation - Promotes Integrity of Skin and Lips - Collagen Support - Amino Acids - Non-GMO, Vegan, Gluten Free - 250 Servings

9.7

8.9

8.7

3

Nature Made L-Lysine 1000 mg, Dietary Supplement, 60 Tablets, 60 Day Supply

8.4

8.0

8.0

4

NOW Foods Supplements, (L-Lysine Hydrochloride) 1,000 mg, Double Strength, Amino Acid, 100 Tablets

9.5

8.9

8.2

5

Bronson L-Lysine Defense Immune Support Complex 1500 MG L-Lysine Plus Olive Leaf, Garlic, Vitamin C and Zinc - Non-GMO, 90 Vegetarian Capsules

9.5

9.3

9.1

6

Pure Encapsulations L-Lysine - Essential Amino Acid Supplement for Immune Support & Gum, Lip Health* - with L-Lysine HCl - 90 Capsules

9.9

9.7

9.7

7

NOW Foods Supplements, L-Lysine (L-Lysine Monohydrochloride) 500 mg, Amino Acid, 100 Veg Capsules

9.5

9.1

8.9

8

Best Naturals L-Lysine 1000mg 180 Tablets - Double Strength Lysine for stronger immune health & cold sores

9.5

8.7

8.7

9

Nature's Bounty L-Lysine, 1000mg, 60 Tablets

10

THORNE - Lysine - Essential Amino Acid for Skin Health, Energy Production, and Immune Function* - 500 mg - 60 Capsules

9.9

9.7

9.5

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