10 Best leptin supplements of 2025

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1

Dr. Westin Childs
Dr. Westin Childs | Leptin Resistance Rx – Natural Leptin Sensitizer Support Supplement for Women for Thyroid, Metabolic Health, Vitality, Energy, Focus with Glycosaminoglycans, Vitamin C - 60 ct
Main highlights

Leptin Sensitivity Enhancement
Supports leptin sensitivity, hormone balance, and thyroid function for a slender physique.

Ideal for Weight Management
Best used with exercise, whole foods, and intermittent fasting for optimal results.

Energy and Focus Boost
Customers love the boost in energy and focus it provides.
9.7

Exceptional

Our Rating
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Value for Money

2

Health As It Ought To Be

Health As It Ought To Be Leptin Syn3rgy Supplement | Physician Formulated Capsules with Green Tea, African Mango, Ginseng | 60 Capsules
9.5

Excellent

Our Rating
3

NatureGenX
NatureGenX LeptinXT - Leptin Supplements for Weight Loss for Women, Healthy Fat Burner Pills, Advanced Strength Fat Burners for Women Weight Loss, Ideal Womens Fat Burner & Diet Pills, 60 Ct.
Main highlights

Supports Weight Loss Goals
NatureGenX Leptin XT helps reduce calorie intake by influencing leptin hunger hormones, best combined with a calorie-controlled diet and exercise.

Ideal for Women Seeking Natural Weight Loss
Crafted with natural ingredients like garcinia cambogia, green tea extract, and raspberry ketones, it supports women's weight loss journey and appetite control.

Customer Praise for Appetite Suppression
Users appreciate its ability to curb hunger, reduce binge eating, and increase energy levels, contributing to a more active and focused lifestyle.
9.4

Excellent

Our Rating
4

Power By Naturals
Power By Naturals Advanced Leptin Supplements for Weight Loss for Women, African Mango Leptin Weight Loss, Gluten-Free, Dietary Supplements for Weight Loss, Vegetarian, Easy to Swallow, 60 Capsules
Main highlights

Key Features and Benefits
Natural weight management with leptin optimization, reduces cravings, and promotes fat utilization, enriched with caffeine and green tea for energy and focus.

Ideal Use Cases
Best for women seeking a natural approach to balance diet, reduce hunger, and support an active lifestyle with mental clarity and energy.

Customer Reviews Highlight
Most praised for effectively reducing cravings and boosting energy without artificial ingredients, leading to noticeable weight management results.
9.3

Excellent

Our Rating

8.0
Flavor

8.0
worth the money
5

CaelumCore
CaelumCore Liposomal Berberine HCL - Berberine 1500mg Activates AMPK & GLP-1, High Bioavailability Berberines Supplement for Women and Men, Berberine Plus Overall Health Support (1 Pack)

16% Off
Main highlights

High Bioavailability and Potency
Liposomal Berberine HCL offers 6X enhanced absorption, delivering 1500mg in just one capsule for superior health support.

Ideal for Weight Management and Metabolic Health
Activates AMPK & GLP-1 for energy, appetite control, and effective weight loss.

Praised for Effective Weight Loss
Customers report steady weight loss and improved energy levels with no side effects.
9.0

Excellent

Our Rating
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6

Power By Naturals
Power By Naturals Leptin Detox Cleanse for Reduce Weight - Natural Gut & Colon Cleanser, 1532mg, Acai Berry Cleanse for Men & Women, 60 Capsules, USA-Made
Main highlights

Kick-Start Healthy Weight Loss & Colon Cleanser
This detox formula naturally increases energy, flushes excess waste and toxins, and supports healthy digestion with all-natural ingredients.

Ideal for Overindulgence & Digestive Issues
Perfect for those struggling with gas, bloating, or following a ketogenic diet. Also great for rebooting before starting a diet.

Praised for Gentle & Effective Detox
Customers love that it works fast without causing cramps or constipation, helps with bloating, and increases energy levels.
8.9

Very Good

Our Rating

9.9
simple to consume

9.3
quality of ingredients

8.0
pain management
7

IDEAL PERFORMANCE

Leptithin Max Keto Capsules, LeptithinMax Advanced Formula Supplement Pills - Maximum Strength, Leptithin Max All Natural Keto Pills, LeptithinMax Capsules, Leptithin Max Pills Reviews (60 Capsules)
8.8

Very Good

Our Rating
8

Power By Naturals
Power By Naturals Leptin Detox & Leptin Burn Supplements | Natural Weight Loss, Appetite Suppressant, Metabolism Booster & Digestive Support | Thermogenic Fat Burner | 60 Count
Main highlights

Healthy Weight Loss and Detox
Before starting a diet, reboot your metabolism with this detox formula. Naturally increases energy, flushes toxins, and supports keto diet by reducing gas and bloating.

Ideal for Weight Management and Mood Support
Perfect for those on keto diet or anyone needing appetite control, energy boost, and enhanced mood. Natural thermogenic fat burners target belly fat.

Customer Praises for Effective Weight Loss
Many users report significant weight loss and reduced cravings. Notable reviews mention losing up to 8 lbs, reduced need for coffee, and improved mood.
8.6

Very Good

Our Rating
9

Vivaravida
Berberine HCl Supplement 3000 mg - Liposomal Berberine HCl Liquid - AMPK Activator with Turmeric, Ceylon Cinnamon, 12 Natural Ingredients - 2 fl oz

23% Off
Main highlights

High Purity and Fast Absorption
Berberine Drops 3000mg with liposomal delivery for efficient AMPK activation and rapid absorption.

Ideal for Weight Management
Supports metabolism regulation and appetite control, aiding in weight loss journeys.

Praised for Natural Ingredients
Customers appreciate the clean, gluten-free, and dairy-free formulation.
8.5

Good

Our Rating
10

Clean Nutraceuticals
Clean Nutraceuticals Sea Moss Black Seed Oil Ashwagandha Turmeric Bladderwrack Burdock & Vitamin C Vitamin D3 with Elderberry Manuka Dandelion Yellow Dock Iodine Chlorophyll ACV

40% Off
Main highlights

Comprehensive Nutritional Blend
Combines 15 powerful ingredients including Sea Moss, Black Seed Oil, Ashwagandha, and Turmeric for overall health and wellness.

Ideal for Daily Wellness
Supports digestion, energy, mental clarity, and sleep, making it perfect for daily health maintenance.

Boosts Energy Levels
Customers frequently praise the energy boost and improved focus without jitters or crashes.
8.3

Good

Our Rating

10 Best leptin supplements of 2025

1

Dr. Westin Childs | Leptin Resistance Rx – Natural Leptin Sensitizer Support Supplement for Women for Thyroid, Metabolic Health, Vitality, Energy, Focus with Glycosaminoglycans, Vitamin C - 60 ct

2

Health As It Ought To Be Leptin Syn3rgy Supplement | Physician Formulated Capsules with Green Tea, African Mango, Ginseng | 60 Capsules

3

NatureGenX LeptinXT - Leptin Supplements for Weight Loss for Women, Healthy Fat Burner Pills, Advanced Strength Fat Burners for Women Weight Loss, Ideal Womens Fat Burner & Diet Pills, 60 Ct.

4

Power By Naturals Advanced Leptin Supplements for Weight Loss for Women, African Mango Leptin Weight Loss, Gluten-Free, Dietary Supplements for Weight Loss, Vegetarian, Easy to Swallow, 60 Capsules

8.0

8.0

5

CaelumCore Liposomal Berberine HCL - Berberine 1500mg Activates AMPK & GLP-1, High Bioavailability Berberines Supplement for Women and Men, Berberine Plus Overall Health Support (1 Pack)

6

Power By Naturals Leptin Detox Cleanse for Reduce Weight - Natural Gut & Colon Cleanser, 1532mg, Acai Berry Cleanse for Men & Women, 60 Capsules, USA-Made

9.9

9.3

8.0

7

Leptithin Max Keto Capsules, LeptithinMax Advanced Formula Supplement Pills - Maximum Strength, Leptithin Max All Natural Keto Pills, LeptithinMax Capsules, Leptithin Max Pills Reviews (60 Capsules)

8

Power By Naturals Leptin Detox & Leptin Burn Supplements | Natural Weight Loss, Appetite Suppressant, Metabolism Booster & Digestive Support | Thermogenic Fat Burner | 60 Count

9

Berberine HCl Supplement 3000 mg - Liposomal Berberine HCl Liquid - AMPK Activator with Turmeric, Ceylon Cinnamon, 12 Natural Ingredients - 2 fl oz

10

Clean Nutraceuticals Sea Moss Black Seed Oil Ashwagandha Turmeric Bladderwrack Burdock & Vitamin C Vitamin D3 with Elderberry Manuka Dandelion Yellow Dock Iodine Chlorophyll ACV

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