10 Best itch relief sprays of 2025

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Best Choice

1

Tecnu

Tecnu Rash Relief Medicated Anti Itch Spray with Scar Prevention, 6 Fl Oz, (3 Pack) Protection & Itchy Skin Relief from Poison Ivy, Poison Oak, Rashes, Insect Bites & Sunburn, Homeopathic Skin Care
9.8

Exceptional

Our Rating
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Value for Money

2

DCH Labs
DCH Labs Itch Relief CalaSpray: Fast Itch Relief from Poison Ivy, Oak, Sumac, and Minor Scrapes & Cuts, 3 Ounces (2-Pack)
Main highlights

Fast Itch and Pain Relief
Contains Pramoxine HCI 1% and Zinc Acetate 0.10% for quick relief from poison ivy, oak, sumac, insect bites, and minor cuts.

Ideal for Outdoor Enthusiasts
Perfect for gardeners, hikers, campers, and anyone frequently outdoors, providing easy application and effective relief.

Touch-Free Application
Highly praised for its no-touch spray application that prevents spreading rash-causing oils.
Key specs
- Application Method:Continuous spray
- Type of Relief:Pain & itch relief
- Formulation:Spray
- Usage Instructions:Spray on affected area
- Product Dimensions:4 x 2 x 6.5 inches
9.7

Exceptional

Our Rating
3

Benadryl

Benadryl Extra Strength Itch Cooling Spray, Topical Analgesic Spray with Diphenhydramine HCI & Zinc Acetate Skin Protectant for Fast Relief from Insect Bites, Travel Size, 2 fl. oz

22% Off
9.6

Exceptional

Our Rating

9.9
pain management

9.7
Simple to use

9.5
Easy to grip
4

Cortizone 10
Cortizone 10 Maximum Strength Soothing Aloe Itch Relief Cooling Spray, 1% Hydrocortisone, Fast-Acting, Anti-Itch Spray for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac, 2.7 oz
Main highlights

Fast Relief and Cooling
Provides fast-acting relief with a cooling mist for itch and irritation.

Versatile Use Cases
Ideal for insect bites, rashes, eczema, psoriasis, and poison ivy.

Praised Application Method
Customers love the upside-down spray feature for hard-to-reach areas.
Key specs
- form:Spray
- size:2.7 oz
- cream type:Cooling Spray
- active ingredient:Hydrocortisone 1
- application method:Spray
9.5

Excellent

Our Rating
5

Dermoplast
Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz (Packaging May Vary)

13% Off
Main highlights

Fast Pain and Itch Relief
Dermoplast provides quick relief from minor cuts, burns, and bug bites with hospital-strength Benzocaine.

Ideal for Postpartum and Family Use
Perfect for postpartum care and soothing children's minor injuries, offering no-touch application.

Highly Effective and Easy to Use
Customers praise its instant cooling effect and versatility for various skin irritations.
9.4

Excellent

Our Rating

9.7
Simple to use

9.1
worth the money

8.9
pain management
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6

Bactine MAX
Bactine MAX First Aid Spray - Cleansing Spray with 4% Lidocaine - Relief for Minor Cuts, Burns & Bug Bites - 5oz
Main highlights

Max Relief and Germ Protection
Bactine MAX provides pain and itch relief while killing 99% of germs.

Ideal for Minor Injuries
Perfect for cuts, scrapes, burns, bug bites, and sunburns.

No-Sting Application Praised
Customers appreciate the sting-free application, even on sensitive skin.
9.3

Excellent

Our Rating

9.7
Simple to use

9.3
pain management

8.7
Easy to grip
7

Benadryl
Benadryl Extra Strength Anti Itch Relief Gel, 2% Diphenhydramine HCl, Relief from Insect Bites, Sunburn & More, Great for Camping Essentials, 3.5 fl oz

25% Off
Main highlights

Fast-Acting Cooling Relief
Benadryl Extra Strength Gel provides quick relief from itching and pain caused by insect bites, sunburn, and minor skin irritations.

Outdoor Activity Essential
Ideal for camping, hiking, and outdoor events, offering relief for ages 2 and up.

Instant Itch Control
Customers praise its immediate itch relief and cooling sensation, making it a must-have for skin irritations.
Key specs
- Item Form:Gel
- Recommended Use:Insect bites, sunburn
- Dimensions:1.47 x 2.43 x 6.35 inches
- Special Feature:Anti-itch relief
- Reusability:N/A
9.0

Excellent

Our Rating

8.7
Simple to use

8.4
worth the money

8.4
For traveling
8

Aquaphor
Aquaphor Itch Relief Ointment, Maximum Strength 1% Hydrocortisone, Relieves Itch from Skin Irritation, Insect Bites, Psoriasis, Skin Rashes, Eczema, & Poison Ivy, 2 oz
Main highlights

Long Lasting Itch Relief
Aquaphor Itch Relief ointment provides soothing relief for up to 12 hours.

Versatile Use Cases
Ideal for insect bites, poison ivy, dry skin, and psoriasis.

Praised Texture
Customers appreciate its long-lasting effect, despite its Vaseline-like texture.
Key specs
- form:Tube
- size:2 ounces
- cream type:Itch Relief Ointment
- active ingredient:1% hydrocortisone
- application method:Ointment
8.9

Very Good

Our Rating

8.7
pain management

8.2
quality of ingredients

8.0
Moisturizing
9

Tecnu
Tecnu Rash Relief Medicated Anti Itch Spray with Scar Prevention, 6 Fl Oz, Protection & Itchy Skin Relief from Poison Ivy, Poison Oak, Rashes, Insect Bites & Sunburn, Homeopathic Skin Care
Main highlights

Immediate Relief and Scar Prevention
Offers quick relief from itching and promotes healing without scarring.

Versatile Outdoor Use
Ideal for insect bites, poison ivy, and minor burns—perfect for outdoor enthusiasts.

Highly Effective Itch Stopper
Customers praise its ability to stop itching quickly and effectively.
Key specs
- Application Method:Spray
- Type of Relief:Pain & itching relief
- Formulation:Homeopathic formula
- Usage Instructions:Spray on affected area
- Product Dimensions:2 x 2 x 6.25 inches
8.8

Very Good

Our Rating

9.5
Comfort

9.1
Simple to use

8.2
worth the money
10

Westlake HB Pharma

Westlake Extra Strength Itch Relief Spray, Diphenhydramine HCl 2% | Relieves Pain and Itching of Insect Bites, Poison Ivy, Sunburn, Minor Cuts | 2 Pack
8.6

Very Good

Our Rating

10 Best itch relief sprays of 2025

1

Tecnu Rash Relief Medicated Anti Itch Spray with Scar Prevention, 6 Fl Oz, (3 Pack) Protection & Itchy Skin Relief from Poison Ivy, Poison Oak, Rashes, Insect Bites & Sunburn, Homeopathic Skin Care

How do we rank?

How do we rank?

Analyzing top stores

2

DCH Labs Itch Relief CalaSpray: Fast Itch Relief from Poison Ivy, Oak, Sumac, and Minor Scrapes & Cuts, 3 Ounces (2-Pack)

3

Benadryl Extra Strength Itch Cooling Spray, Topical Analgesic Spray with Diphenhydramine HCI & Zinc Acetate Skin Protectant for Fast Relief from Insect Bites, Travel Size, 2 fl. oz

9.9

9.7

9.5

4

Cortizone 10 Maximum Strength Soothing Aloe Itch Relief Cooling Spray, 1% Hydrocortisone, Fast-Acting, Anti-Itch Spray for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac, 2.7 oz

5

Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz (Packaging May Vary)

9.7

9.1

8.9

6

Bactine MAX First Aid Spray - Cleansing Spray with 4% Lidocaine - Relief for Minor Cuts, Burns & Bug Bites - 5oz

9.7

9.3

8.7

7

Benadryl Extra Strength Anti Itch Relief Gel, 2% Diphenhydramine HCl, Relief from Insect Bites, Sunburn & More, Great for Camping Essentials, 3.5 fl oz

8.7

8.4

8.4

8

Aquaphor Itch Relief Ointment, Maximum Strength 1% Hydrocortisone, Relieves Itch from Skin Irritation, Insect Bites, Psoriasis, Skin Rashes, Eczema, & Poison Ivy, 2 oz

8.7

8.2

8.0

9

Tecnu Rash Relief Medicated Anti Itch Spray with Scar Prevention, 6 Fl Oz, Protection & Itchy Skin Relief from Poison Ivy, Poison Oak, Rashes, Insect Bites & Sunburn, Homeopathic Skin Care

9.5

9.1

8.2

10

Westlake Extra Strength Itch Relief Spray, Diphenhydramine HCl 2% | Relieves Pain and Itching of Insect Bites, Poison Ivy, Sunburn, Minor Cuts | 2 Pack

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