Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
Advertising Disclosure
10 Best itch relief for humans of 2025
Explore up to 26% off
- Best Choice
1
Clicked 12 times in the last monthMED PRIDEMED PRIDE Hydrocortisone Cream 1% Maximum Strength Itch Relief, Bulk 16 Oz Hydro Cortisone Cream for Eczema, Dermatitis, Mosquito Bites
- Curious about how we select the top products for you? Explore How It Works
- Value for Money
2
AquaphorAquaphor Itch Relief Ointment, Maximum Strength 1% Hydrocortisone, Relieves Itch from Skin Irritation, Insect Bites, Psoriasis, Skin Rashes, Eczema, & Poison Ivy, 2 oz
3
BenadrylBenadryl Anti Itch Gel, Relief of Outdoor Itches Associated with Poison Ivy, Topical Analgesic, Cooling Relief, Diphenhydramine, 3.5 oz
25% Off4
BenadrylBenadryl Extra Strength Anti-Itch Cooling Spray, Diphenhydramine HCI Topical Analgesic and Zinc Acetate Skin Protectant for Fast Relief from Most Outdoor Itches, Travel Size, 2 fl. oz
22% Off5
Cortizone 10Cortizone 10 Maximum Strength Itch Relief Cooling Spray, Hydrocortisone 1% & Soothing Aloe, Fast-Acting, No-Mess Anti-Itch Spray for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy & More, 2.7 oz.
-
See Today’s Deals & Prices
6
Cortizone 10Cortizone 10 Maximum Strength Fast Itch Relief with Massaging Rollerball, 1% Hydrocortisone Anti-Itch Liquid, 1.5 oz.
15% Off7
BenadrylBenadryl Extra Strength Anti-Itch Topical Cream with 2% Diphenhydramine HCI for Itch Relief of Outdoor Itches Associated with Poison Ivy, Insect Bites & More, 1 fl oz
26% Off8
SarnaSarna Sensitive Steroid-Free Anti-Itch Lotion for Dry Irritated Skin, Fragrance free - 7.5 Fl Oz
9
BenadrylBenadryl Extra Strength Itch Relief Stick, Diphenhydramine HCL Topical Analgesic & Zinc Acetate to Relieve Skin Itching & Pain Associated with Insect Bites, Sunburn & More, 0.47 fl. oz
10
Cortizone 10Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.