10 Best itch relief creams of 2025

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CeraVe

CeraVe Moisturizing Cream for Itch Relief, Anti Itch Cream with Pramoxine Hydrochloride, Relieves Itchy with Minor Skin Irritations, Sunburn Relief, Bug Bites, Fragrance Free, 16 Ounces

17% Off
9.8

Exceptional

Our Rating
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Value for Money

2

CeraVe
CeraVe Anti Itch Moisturizing Lotion with Pramoxine Hydrochloride, Relieves Itch with Minor Skin Irritations, Sunburn Relief, Bug Bites, 8 Ounce
Main highlights

Fast-Acting Relief
Provides quick relief from itching due to insect bites, sunburn, and poison ivy, while moisturizing skin.

Versatile Use
Ideal for minor skin irritations, dry skin, and occasional itchy patches.

Moisturizing Benefit
Highly praised for combining itch relief with effective skin hydration.
9.5

Excellent

Our Rating

9.1
Moisturizing

8.9
Aroma

8.9
Comfort
3

Benadryl
Benadryl Extra Strength Anti Itch Relief Gel, 2% Diphenhydramine HCl, Relief from Insect Bites, Sunburn & More, Great for Camping Essentials, 3.5 fl oz

26% Off
Main highlights

Fast-Acting Cooling Relief
Benadryl Extra Strength Gel provides quick relief from itching and pain caused by insect bites, sunburn, and minor skin irritations.

Outdoor Activity Essential
Ideal for camping, hiking, and outdoor events, offering relief for ages 2 and up.

Instant Itch Control
Customers praise its immediate itch relief and cooling sensation, making it a must-have for skin irritations.
Key specs
- Item Form:Gel
- Recommended Use:Insect bites, sunburn
- Dimensions:1.47 x 2.43 x 6.35 inches
- Special Feature:Anti-itch relief
- Reusability:N/A
9.2

Excellent

Our Rating

8.7
Simple to use

8.4
worth the money

8.4
For traveling
4

Cortizone 10
Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz
Main highlights

Maximum Strength Relief
Contains 1% hydrocortisone for fast, effective itch relief.

Ideal for Itch and Irritation
Perfect for eczema, psoriasis, insect bites, and rashes.

Praised for Quick Absorption
Non-greasy formula absorbs quickly, leaving no residue.
Key specs
- form:Cream
- size:2 oz.
- cream type:Anti-Itch Cream
- active ingredient:1% hydrocortisone
- application method:Topical
9.0

Excellent

Our Rating
5

Cortizone-10
Cortizone-10 Maximum Strength Intensive Healing Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz
Main highlights

Maximum Strength Itch Relief
Cortizone-10 provides fast relief from itch with maximum-strength hydrocortisone and nourishing moisturizers.

Ideal for Minor Skin Irritations
Perfect for relieving itch from dry, chafed, and chapped skin.

Instant Relief and No Grease
Highly praised for its quick action and non-greasy feel.
Key specs
- form:Cream
- size:2-oz. tube
- cream type:Anti-Itch Cream
- active ingredient:1 hydrocortisone
- application method:Topical
8.9

Very Good

Our Rating
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6

Amazon Basic Care
Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, Itch Relief For Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Pack of 1)
Main highlights

Maximum Strength Relief
Contains hydrocortisone 1% for fast, effective itch relief.

Versatile Use Cases
Ideal for bug bites, eczema, psoriasis, and poison ivy.

Highly Praised Value
Works as well as name brands at a lower price.
Key specs
- form:Cream
- size:1.45 ounces
- cream type:Anti-itch cream
- active ingredient:Hydrocortisone 1 percent
- application method:Cream
8.7

Very Good

Our Rating

9.9
quality of ingredients

9.7
Moisturizing

9.1
Aroma
7

Benadryl
Benadryl Extra Strength Itch Stopping Cream, Topical Analgesic Cream with Diphenhydramine HCl & Zinc Acetate Skin Protectant, Anti-Itch Ointment for Insect Bite & Sunburn Relief, 1 oz

30% Off
Main highlights

Effective Relief for Itching and Pain
Benadryl Extra Strength Anti-Itch Cream offers fast relief from itching and pain caused by insect bites, sunburn, and other minor skin irritations.

Ideal for Outdoor Enthusiasts
Perfect for camping, hiking, and other outdoor activities, providing on-the-go relief for common outdoor itches.

Highly Praised for Quick Itch Relief
Customers appreciate the cream's ability to quickly alleviate itching from mosquito and other insect bites.
Key specs
- Item Form:Cream
- Recommended Use:Insect bites, sunburn
- Dimensions:9.06 x 4.88 x 1.19 inches
- Special Feature:Anti-itch relief
- Reusability:N/A
8.6

Very Good

Our Rating

9.5
pain management

8.9
Simple to use

8.2
worth the money
8

Cortizone-10
Cortizone-10 Maximum Strength Intensive Healing Itch Relief Lotion for Eczema, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Minor Skin Irritations, Rashes and Inflammation Due to Eczema, 3.5 oz
Main highlights

Maximum Strength Itch Relief
Contains 1% hydrocortisone for fast relief of itch and inflammation.

Ideal for Eczema and Dry Skin
Clinically proven to moisturize for 24 hours, perfect for eczema.

Instant Itch Reduction
Customers praise its immediate effectiveness in reducing itchiness.
8.5

Good

Our Rating

9.7
Moisturizing

9.5
worth the money

9.5
Fashion
9

Gold Bond
Gold Bond Medicated Maximum Strength Pain & Itch Relief Cream, 1.75 oz., with Lidocaine
Main highlights

Maximum Strength Lidocaine Formula
Contains 4% lidocaine, the highest strength available without a prescription, providing fast and effective relief from itching and pain.

Effective for Various Skin Irritations
Ideal for relieving pain and itch associated with sunburn, insect bites, minor cuts, burns, and scrapes.

Fast-Acting and Long-Lasting Relief
Customers praise its quick action in stopping itching and its effectiveness in providing long-lasting relief from severe skin irritations.
Key specs
- form:Cream
- size:1.75 oz
- cream type:Pain & Itch Relief
- active ingredient:Lidocaine
- application method:Topical
8.4

Good

Our Rating

9.9
pain management

9.3
worth the money

8.7
Moisturizing
10

Cortizone 10
Cortizone-10 Maximum Strength Water Resistant Itch Relief Ointment, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz
Main highlights

Key Features
Maximum-strength 1% hydrocortisone ointment, water-resistant, fast itch relief for eczema, psoriasis, poison plants, fragrance and dye free.

Ideal Use
Exceptional for quickly soothing eczema, psoriasis, and reactions to poison oak, ivy, sumac, locking in moisture for longer-lasting comfort.

Customer Praise
Reviews highlight rapid itch relief in under 10 minutes and long-lasting effectiveness, appreciating its fragrance-free and dye-free formula.
Key specs
- form:tube
- size:2-oz.
- cream type:Anti-Itch Ointment
- active ingredient:1 percent hydrocortisone
- application method:ointment
8.3

Good

Our Rating

10 Best itch relief creams of 2025

1

CeraVe Moisturizing Cream for Itch Relief, Anti Itch Cream with Pramoxine Hydrochloride, Relieves Itchy with Minor Skin Irritations, Sunburn Relief, Bug Bites, Fragrance Free, 16 Ounces

How do we rank?

How do we rank?

Analyzing top stores

2

CeraVe Anti Itch Moisturizing Lotion with Pramoxine Hydrochloride, Relieves Itch with Minor Skin Irritations, Sunburn Relief, Bug Bites, 8 Ounce

9.1

8.9

8.9

3

Benadryl Extra Strength Anti Itch Relief Gel, 2% Diphenhydramine HCl, Relief from Insect Bites, Sunburn & More, Great for Camping Essentials, 3.5 fl oz

8.7

8.4

8.4

4

Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

5

Cortizone-10 Maximum Strength Intensive Healing Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

6

Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, Itch Relief For Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Pack of 1)

9.9

9.7

9.1

7

Benadryl Extra Strength Itch Stopping Cream, Topical Analgesic Cream with Diphenhydramine HCl & Zinc Acetate Skin Protectant, Anti-Itch Ointment for Insect Bite & Sunburn Relief, 1 oz

9.5

8.9

8.2

8

Cortizone-10 Maximum Strength Intensive Healing Itch Relief Lotion for Eczema, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Minor Skin Irritations, Rashes and Inflammation Due to Eczema, 3.5 oz

9.7

9.5

9.5

9

Gold Bond Medicated Maximum Strength Pain & Itch Relief Cream, 1.75 oz., with Lidocaine

9.9

9.3

8.7

10

Cortizone-10 Maximum Strength Water Resistant Itch Relief Ointment, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

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