10 Best hypoallergenic formulas of 2025

Explore top picks

Best Choice

1

Enfamil
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz, 4 Count
Main highlights

Key Features
Clinically proven colic relief, contains LGG probiotic for allergy management, and supports brain development with DHA, ARA, and choline.

Ideal Use Cases
Best for babies with cow`s milk allergy, showing colic symptoms, and families seeking a formula that supports immune health and brain development.

Customer Reviews
Most praised for providing fast relief from colic symptoms, with noticeable improvements within 48 hours, and being a trusted choice among pediatricians.
9.8

Exceptional

Our Rating

8.9
Comfort

8.0
worth the money

8.0
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Value for Money

2

Enfamil

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 12.6 Oz Can, Pack of 6
9.7

Exceptional

Our Rating

8.9
Comfort

8.0
worth the money

8.0
For traveling
3

Enfamil
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz Can
Main highlights

Clinically Proven Colic Relief
Delivers clinically proven relief from colic due to cow's milk allergy, ensuring a happier, better-rested baby and mom.

Best for Dairy Allergies
Ideal for babies with dairy or soy allergies, providing gentle, lactose-free nutrition with omega-3 DHA, ARA, and choline for brain development.

Effective Allergy Management
Most customer reviews praise how effectively it manages dairy allergies and reduces digestive issues, ensuring a comfortable and happy baby.
Key specs
- milk source:Cow's milk
- nutrition type:Hypoallergenic formula
- age range:0 - 10 months
- ingredients:Omega-3 DHA, ARA, choline
- digestibility:Gentle, lactose-free
9.4

Excellent

Our Rating

9.9
quality of ingredients

8.0
worth the money

8.0
Packaging materials
4

Enfamil
Enfamil Nutramigen Baby Formula, Hypoallergenic and Lactose Free Formula with Enflora LGG, Fast Relief from Severe Crying and Colic, Powder Can, 19.8 Oz (Pack of 1)
Main highlights

Clinically Proven Relief
Delivers fast relief from colic due to cow's milk allergy, soothing your baby quickly.

Ideal for Sensitive Tummies
Perfect for babies with lactose intolerance and milk allergies, ensuring comfort.

Highly Praised Probiotic
Parents love the LGG Probiotic for improving digestive health and reducing colic symptoms.
9.3

Excellent

Our Rating
5

NUTRICIA PEPTICATE

Pepticate Baby Formula, Hypoallergenic Powdered Infant Formula for Cow Milk Allergy, with Omega 3 DHA, ARA, Iron & Prebiotics, 13.2oz
9.2

Excellent

Our Rating
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6

Similac
Similac Alimentum with 2'-FL HMO Hypoallergenic Infant Formula, for Food Allergies and Colic Due to Protein Sensitivity, Ready-to-Feed Baby Formula, 8-fl-oz Bottle, Pack of 24
Main highlights

Hypoallergenic Formula with Immune Support
Similac Alimentum is hypoallergenic with 2-FL HMO for immune support.

Ideal for Babies with Milk Protein Allergies
Perfect for infants with cow's milk protein allergies and colic.

Quick Relief from Colic Symptoms
Most parents praise its effectiveness in reducing colic quickly.
9.1

Excellent

Our Rating
7

Enfamil
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 32 Fl Oz, 6 Count
Main highlights

Key Features and Benefits
Clinically proven colic relief due to cow`s milk allergy, supports brain development, and boosts immunity; pediatrician trusted, lactose-free formula.

Ideal Use Cases
Perfect for babies with cow`s milk allergy showing colic symptoms, needing fast, gentle relief and nutritional support for brain and immune system.

Customer Reviews Summary
Most praised for providing quick and effective relief from colic symptoms, making it a life-changer for both babies and parents.
Key specs
- Nutrition:Lactose-free formula
- Ready-to-Use:Yes
- Form:Liquid
- DHA:Omega-3 DHA
- Recommended Age:0 - 1 years
9.0

Excellent

Our Rating

8.9
Comfort

8.0
worth the money

8.0
For traveling
8

Nutramigen
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Concentrated Liquid, 8 Fl Oz, 24 Bottles
Main highlights

Key Features
Clinically proven to ease colic from cow`s milk allergy within 48 hours, supports brain development, and strengthens immunity. Pediatrician-recommended, lactose-free formula.

Ideal Use Cases
Perfect for babies with colic due to cow`s milk allergy, needing fast relief, and parents seeking a nutrient-rich, hypoallergenic option for brain development and immunity support.

Customer Praise
Most reviews highlight the quick, effective relief for colicky babies and the convenience of the ready-to-feed formula, greatly appreciated by satisfied parents.
Key specs
- Nutrition:Clinically proven relief
- Ready-to-Use:Ready-to-feed
- Form:Lactose-free formula
- DHA:Omega-3 DHA, ARA, choline
- Recommended Age:N/A
8.9

Very Good

Our Rating
9

Similac
Similac Alimentum With 2'-FL HMO Hypoallergenic Infant Formula, for Food Allergies and Colic Due to Protein Sensitivity, Baby Formula Powder, 12.1-oz Can
Main highlights

Hypoallergenic Formula Benefits
Contains milk protein broken down to eliminate allergic reactions, reduces colic symptoms within 24 hours, and includes immune-nourishing 2-FL HMO.

Ideal For Colic and Allergies
Best for infants with cow's milk protein allergies and colic symptoms, providing relief and nutrition quickly.

Praised for Reducing Vomiting
Parents report reduced vomiting and improved tolerance, though frequent use means going through a can in 3 days.
Key specs
- milk source:Cow's milk protein
- nutrition type:Hypoallergenic formula
- age range:Most infants
- ingredients:Milk protein broken down
- digestibility:Reduces colic symptoms
8.7

Very Good

Our Rating

9.9
quality of ingredients

9.9
For Gentle skin

8.0
worth the money
10

EleCare

EleCare Hypoallergenic Amino Acid-Based Infant Formula, Complete Nutrition for Food Allergies and GI Conditions, Amino Acid-Based Baby Formula Powder, 14.1-oz Can
8.5

Good

Our Rating

10 Best hypoallergenic formulas of 2025

1

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz, 4 Count

8.9

8.0

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 12.6 Oz Can, Pack of 6

8.9

8.0

8.0

3

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz Can

9.9

8.0

8.0

4

Enfamil Nutramigen Baby Formula, Hypoallergenic and Lactose Free Formula with Enflora LGG, Fast Relief from Severe Crying and Colic, Powder Can, 19.8 Oz (Pack of 1)

5

Pepticate Baby Formula, Hypoallergenic Powdered Infant Formula for Cow Milk Allergy, with Omega 3 DHA, ARA, Iron & Prebiotics, 13.2oz

6

Similac Alimentum with 2'-FL HMO Hypoallergenic Infant Formula, for Food Allergies and Colic Due to Protein Sensitivity, Ready-to-Feed Baby Formula, 8-fl-oz Bottle, Pack of 24

7

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 32 Fl Oz, 6 Count

8.9

8.0

8.0

8

Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Concentrated Liquid, 8 Fl Oz, 24 Bottles

9

Similac Alimentum With 2'-FL HMO Hypoallergenic Infant Formula, for Food Allergies and Colic Due to Protein Sensitivity, Baby Formula Powder, 12.1-oz Can

9.9

9.9

8.0

10

EleCare Hypoallergenic Amino Acid-Based Infant Formula, Complete Nutrition for Food Allergies and GI Conditions, Amino Acid-Based Baby Formula Powder, 14.1-oz Can

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