10 Best herpes treatments of 2025

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Best Choice

1

Herplex
Herplex Premium Tablets | Helps Against Outbreaks & Cold Sores with No Side Effects | Helps to Quickly Ease & Reduce Symptoms of Cold Sore, & Fever Blisters | 60 Tablets
Main highlights

Quick Symptom Relief
These tablets help ease cold sore symptoms quickly with no side effects.

Ideal for Cold Sores
Best used for reducing cold sore outbreaks and fever blisters.

Ease of Use
Customers praise the small, easy-to-swallow tablets for convenience.
Key specs
- active ingredients:Anantherum Muricatum 12x, Clematis Erecta 12x, Mezereum 12x, Phytolacca Decandra 12x, Ranunculus Bulbosus 12x, Rhus Toxicodendron 12x, Thuja Occidentalis 12x, Natrum Muriaticum 30x, Sepia 30x
- weight:1.45 ounces
- formula:Patented homeopathic formula
- pain relief:Rapid relief tablets
- dimensions:3.19 x 1.73 x 1.69 inches
9.8

Exceptional

Our Rating
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Value for Money

2

FemiClear
FemiClear for Genital Herpes Symptoms & Cold Sores, Multi-Symptom - Effective Intimate Relief - Made with All-Natural and Organic Ingredients - 0.5 Ounce Tube
Main highlights

Effective Symptom Relief
FemiClear quickly alleviates discomfort, burning, itching, and tingling sensations associated with herpes outbreaks.

Ideal for Immediate Use
Best used at the first sign of a herpes outbreak for maximum effectiveness.

Praised for Quick Relief
Customers appreciate the rapid relief from symptoms, often within 24 hours.
Key specs
- Usage:Herpes outbreak relief
- Sensitivity:Safe for intimate areas
- Formulation:Topical ointment
- Packaging:0.5-ounce tube
- Active Ingredient:Olive oil, olive extract
9.7

Exceptional

Our Rating
3

Abreva
Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2

22% Off
Main highlights

Fast Healing with Docosanol
Contains 10% docosanol to shorten cold sore duration to 2.5 days.

Ideal for On-the-Go Treatment
Portable tube design perfect for quick, discreet application.

Highly Praised for Effectiveness
Users appreciate fast results and healing of cracked lips.
Key specs
- active ingredients:10% docosanol
- weight:1.76 ounces
- formula:Docosanol cream
- pain relief:Tingling, pain, burning, itching
- dimensions:1.71 x 5.1 x 5.5 inches
9.6

Exceptional

Our Rating

8.7
worth the money

8.4
Flavor
4

NOW Foods
NOW Foods Supplements, (L-Lysine Hydrochloride) 1,000 mg, Double Strength, Amino Acid, 100 Tablets

34% Off
Main highlights

Essential Amino Acid Support
L-Lysine is crucial for collagen synthesis and protein maintenance.

Immune System Boost
Ideal for cold/flu season and preventing viral outbreaks.

Customer Praised Effectiveness
Highly effective in reducing cold sore and shingles severity.
9.5

Excellent

Our Rating

9.5
worth the money

8.9
Absorbency

8.2
Flavor
5

Bravado Labs
Bravado Labs L-Lysine 1000mg Capsules – Immune & Cold Sore Support – Vegan, Non-GMO, Allergen-Free, 3rd-Party Tested, Lisina 1000 mg Organica - Made in USA

20% Off
Main highlights

Comprehensive Immune Support
HrpRX offers advanced lysine formula with vitamins and herbs for maximum immune defense.

Ideal for Outbreak Prevention
Best used daily to prevent cold sores and HRP outbreaks.

Quick Response to Symptoms
Customers praise its effectiveness in minimizing outbreak severity and duration.
Key specs
- Absorption:Maximum absorption
- Form:Tablet
- Quality:100% pure, all-natural
- Functions:Immune support, outbreak prevention
- Dosage:1 tablet a day
9.4

Excellent

Our Rating

9.7
simple to consume

9.7
worth the money

8.9
Absorbency
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6

Herstat
Herstat GST Genital Sore Treatment | Fast, Effective Relief from The Symptoms of Genital Herpes
Main highlights

Fast and Effective Relief
Herstat GST quickly soothes itching, burning, and tingling skin, providing effective relief from genital sore symptoms.

Ideal for Sensitive Areas
Designed for inflamed skin in sensitive areas, offering targeted pain relief with an oily ointment base.

Customer Praised Texture
Users appreciate its soothing texture and effectiveness in calming skin discomfort.
Key specs
- active ingredients:Purified Propolis Extract
- weight:0.5 ounces
- formula:Vitamin rich with oils
- pain relief:Targeted pain relief
- dimensions:3.74 x 0.67 x 0.67 inches
9.3

Excellent

Our Rating
7

Herpecin-L
Herpecin-L Pain Relief Treatment for Cold Sores and Fever Blisters, with Lidocaine, numbs Pain and Itch, Protects Against Infection, 0.15 oz

27% Off
Main highlights

Instant Pain Relief
Triple Action treatment numbs pain & itch, protects, and moisturizes.

Ideal for Cold Sores
Best used at the onset of cold sores or fever blisters.

Praised Lidocaine Effect
Customers love the immediate pain relief without numbing the entire lip.
Key specs
- active ingredients:Lidocaine
- weight:0.1 ounces
- formula:Triple Action
- pain relief:Numbs pain & itch
- dimensions:6.18 x 4.33 x 1.18 inches
9.2

Excellent

Our Rating

9.9
pain management

9.3
Moisturizing

8.9
Aroma
8

Mederma
Mederma Fever Blister Discreet Healing Patch - A Patch That Protects and Conceals Cold Sores - 15 Count
Main highlights

Fast Healing Hydrocolloid Gel
Ultra-thin hydrocolloid gel accelerates healing and prevents scabbing.

Discreet Social Use
Ideal for social settings, conceals cold sores effectively.

Pain and Itch Relief
Eliminates pain and itchiness, enhancing comfort during healing.
Key specs
- active ingredients:Hydrocolloid Gel
- weight:0.63 ounces
- formula:Ultra-thin Hydrocolloid
- pain relief:Relieve pain
- dimensions:6.1 x 4.3 x 0.8 inches
9.1

Excellent

Our Rating

8.7
Comfort

8.4
Simple to use

8.4
Sheerness
9

Terramed Just Think Comfort
Herpes Genital Treatment | Herpcare Fast Acting Ointment | Can be Used on Cold Sore | Homeopathic Medicine | Soothes Itching, Tingling & Burning | Relief from The Symptoms of Genital Sore
Main highlights

Rapid Relief and Soothing
HerpCare Ointment provides fast relief for genital herpes, soothing itching and discomfort with a gentle, homeopathic formula.

Ideal for Sensitive Skin
Perfect for men and women, this ointment is easy to apply and gentle on sensitive skin areas.

Praised for Fast Relief
Customers appreciate the ointment's quick action in reducing herpes symptoms and promoting comfort.
Key specs
- Active Ingredients:Kochia Scoparia, Artemisia Extract
- Usage:Apply to affected area
- Form:Ointment
- Packaging:6.3 x 2.95 x 1.93 inches
- Indications:Genital herpes, sores
8.9

Very Good

Our Rating
10

terrasil
Terragen HG Formula MAX by terrasil, Fast Soothing Natural Treatment Cream for Genital Sores & Effective Outbreak Support, for Men and Women (14g)
Main highlights

Fast Relief & Soothing Ointment
Terragen HG MAX provides quick relief from genital sores using natural ingredients.

Ideal for Daily Use
Perfect for managing genital irritation and outbreaks in men and women.

Praised for Quick Relief
Users appreciate the immediate relief from itching and irritation.
8.8

Very Good

Our Rating

10 Best herpes treatments of 2025

1

Herplex Premium Tablets | Helps Against Outbreaks & Cold Sores with No Side Effects | Helps to Quickly Ease & Reduce Symptoms of Cold Sore, & Fever Blisters | 60 Tablets

How do we rank?

How do we rank?

Analyzing top stores

2

FemiClear for Genital Herpes Symptoms & Cold Sores, Multi-Symptom - Effective Intimate Relief - Made with All-Natural and Organic Ingredients - 0.5 Ounce Tube

3

Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2

8.7

8.4

4

NOW Foods Supplements, (L-Lysine Hydrochloride) 1,000 mg, Double Strength, Amino Acid, 100 Tablets

9.5

8.9

8.2

5

Bravado Labs L-Lysine 1000mg Capsules – Immune & Cold Sore Support – Vegan, Non-GMO, Allergen-Free, 3rd-Party Tested, Lisina 1000 mg Organica - Made in USA

9.7

9.7

8.9

6

Herstat GST Genital Sore Treatment | Fast, Effective Relief from The Symptoms of Genital Herpes

7

Herpecin-L Pain Relief Treatment for Cold Sores and Fever Blisters, with Lidocaine, numbs Pain and Itch, Protects Against Infection, 0.15 oz

9.9

9.3

8.9

8

Mederma Fever Blister Discreet Healing Patch - A Patch That Protects and Conceals Cold Sores - 15 Count

8.7

8.4

8.4

9

Herpes Genital Treatment | Herpcare Fast Acting Ointment | Can be Used on Cold Sore | Homeopathic Medicine | Soothes Itching, Tingling & Burning | Relief from The Symptoms of Genital Sore

10

Terragen HG Formula MAX by terrasil, Fast Soothing Natural Treatment Cream for Genital Sores & Effective Outbreak Support, for Men and Women (14g)

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