10 Best herpes medications of 2025

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Best Choice

1

Herplex
Herplex Premium Tablets | Helps Against Outbreaks & Cold Sores with No Side Effects | Helps to Quickly Ease & Reduce Symptoms of Cold Sore, & Fever Blisters | 60 Tablets
Main highlights

Quick Symptom Relief
These tablets help ease cold sore symptoms quickly with no side effects.

Ideal for Cold Sores
Best used for reducing cold sore outbreaks and fever blisters.

Ease of Use
Customers praise the small, easy-to-swallow tablets for convenience.
Key specs
- application:Oral tablets
- usage:Cold sore symptom relief
- weight:1.45 ounces
- formula:Patented homeopathic formula
- pain relief:Rapid relief tablets
9.7

Exceptional

Our Rating
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Value for Money

2

FemiClear
FemiClear for Genital Herpes Symptoms & Cold Sores, Multi-Symptom - Effective Intimate Relief - Made with All-Natural and Organic Ingredients - 0.5 Ounce Tube
Main highlights

Effective Symptom Relief
FemiClear quickly alleviates discomfort, burning, itching, and tingling sensations associated with herpes outbreaks.

Ideal for Immediate Use
Best used at the first sign of a herpes outbreak for maximum effectiveness.

Praised for Quick Relief
Customers appreciate the rapid relief from symptoms, often within 24 hours.
Key specs
- Usage:Herpes outbreak relief
- Sensitivity:Safe for intimate areas
- Formulation:Topical ointment
- Packaging:0.5-ounce tube
- Active Ingredient:Olive oil, olive extract
9.6

Exceptional

Our Rating
3

Abreva
Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2

20% Off
Main highlights

Fast Healing with Docosanol
Contains 10% docosanol to shorten cold sore duration to 2.5 days.

Ideal for On-the-Go Treatment
Portable tube design perfect for quick, discreet application.

Highly Praised for Effectiveness
Users appreciate fast results and healing of cracked lips.
Key specs
- application:Portable tube
- usage:Cold sore treatment
- weight:1.76 ounces
- formula:Docosanol cream
- pain relief:Tingling, pain, burning, itching
9.5

Excellent

Our Rating

8.7
worth the money

8.4
Flavor
4

Terramed Just Think Comfort
Herpes Genital Treatment | Herpcare Fast Acting Ointment | Can be Used on Cold Sore | Homeopathic Medicine | Soothes Itching, Tingling & Burning | Relief from The Symptoms of Genital Sore
Main highlights

Rapid Relief and Soothing
HerpCare Ointment provides fast relief for genital herpes, soothing itching and discomfort with a gentle, homeopathic formula.

Ideal for Sensitive Skin
Perfect for men and women, this ointment is easy to apply and gentle on sensitive skin areas.

Praised for Fast Relief
Customers appreciate the ointment's quick action in reducing herpes symptoms and promoting comfort.
Key specs
- Active Ingredients:Kochia Scoparia, Artemisia Extract
- Usage:Apply to affected area
- Form:Ointment
- Packaging:6.3 x 2.95 x 1.93 inches
- Indications:Genital herpes, sores
9.3

Excellent

Our Rating
5

Herpecin-L
Herpecin-L Pain Relief Treatment for Cold Sores and Fever Blisters, with Lidocaine, numbs Pain and Itch, Protects Against Infection, 0.15 oz

23% Off
Main highlights

Instant Pain Relief
Triple Action treatment numbs pain & itch, protects, and moisturizes.

Ideal for Cold Sores
Best used at the onset of cold sores or fever blisters.

Praised Lidocaine Effect
Customers love the immediate pain relief without numbing the entire lip.
Key specs
- application:Spot treatment
- usage:Cold sore treatment
- weight:0.1 ounces
- formula:Triple Action
- pain relief:Numbs pain & itch
9.2

Excellent

Our Rating

9.9
pain management

9.3
Moisturizing

8.9
Aroma
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6

terrasil
Terragen HG Formula MAX Genital Sores Cream by terrasil, Fast Soothing Natural Treatment for Effective Outbreak Support for Men and Women (14g)
Main highlights

Fast Relief & Soothing Ointment
Terragen HG MAX provides quick relief from genital sores using natural ingredients.

Ideal for Daily Use
Perfect for managing genital irritation and outbreaks in men and women.

Praised for Quick Relief
Users appreciate the immediate relief from itching and irritation.
9.0

Excellent

Our Rating
7

Terramed Just Think Comfort

Genital Herpes Intimate Wash | Fast Acting HerpCare | Medicated | Soothes Itching, Tingling & Burning | Soothes Genital Herpes & Genital Discomfort
8.9

Very Good

Our Rating
8

Herstat
Herstat GST Genital Sore Treatment | Fast, Effective Relief from The Symptoms of Genital Herpes
Main highlights

Fast and Effective Relief
Herstat GST quickly soothes itching, burning, and tingling skin, providing effective relief from genital sore symptoms.

Ideal for Sensitive Areas
Designed for inflamed skin in sensitive areas, offering targeted pain relief with an oily ointment base.

Customer Praised Texture
Users appreciate its soothing texture and effectiveness in calming skin discomfort.
Key specs
- application:Apply to affected area
- usage:Relieve genital sores pain
- weight:0.5 ounces
- formula:Vitamin rich with oils
- pain relief:Targeted pain relief
8.8

Very Good

Our Rating
9

Campho-Phenique
Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing, Original Gel Formula, 0.23 Oz
Main highlights

Pain and Itch Relief
Specially formulated to instantly relieve pain and itch from cold sores and fever blisters.

Versatile Use
Ideal for treating cold sores, fever blisters, insect bites, and minor sunburns.

Quick Healing
Praised for its ability to speed up healing and provide immediate relief.
Key specs
- application:For adults and children 2 years and over
- usage:For cold sores/fever blisters
- weight:0.23 ounces
- formula:Specially formulated
- pain relief:Instantly relieves pain & itch
8.6

Very Good

Our Rating

9.3
worth the money

8.0
Flavor
10

Basic Organics
Basic Brands L-Lysine Lip Ointment with Camphor, Menthol, Vitamin A & E, 0.875 oz
Main highlights

Cold Sore Prevention and Relief
Contains L-Lysine for effective prevention and relief of lip sores.

Ideal for Sun Exposure and Stress
Perfect for those exposed to sun or stress-induced outbreaks.

Highly Praised for Moisturizing
Customers appreciate its moisturizing effect on chapped lips.
Key specs
- application:Goes on clear
- usage:Lip sores, fever blisters
- weight:1 ounces
- formula:Gluten Free, No Dyes
- pain relief:Lip sores, fever blisters
8.5

Good

Our Rating

9.7
Moisturizing

9.5
quality of ingredients

9.3
pain management

10 Best herpes medications of 2025

1

Herplex Premium Tablets | Helps Against Outbreaks & Cold Sores with No Side Effects | Helps to Quickly Ease & Reduce Symptoms of Cold Sore, & Fever Blisters | 60 Tablets

How do we rank?

How do we rank?

Analyzing top stores

2

FemiClear for Genital Herpes Symptoms & Cold Sores, Multi-Symptom - Effective Intimate Relief - Made with All-Natural and Organic Ingredients - 0.5 Ounce Tube

3

Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2

8.7

8.4

4

Herpes Genital Treatment | Herpcare Fast Acting Ointment | Can be Used on Cold Sore | Homeopathic Medicine | Soothes Itching, Tingling & Burning | Relief from The Symptoms of Genital Sore

5

Herpecin-L Pain Relief Treatment for Cold Sores and Fever Blisters, with Lidocaine, numbs Pain and Itch, Protects Against Infection, 0.15 oz

9.9

9.3

8.9

6

Terragen HG Formula MAX Genital Sores Cream by terrasil, Fast Soothing Natural Treatment for Effective Outbreak Support for Men and Women (14g)

7

Genital Herpes Intimate Wash | Fast Acting HerpCare | Medicated | Soothes Itching, Tingling & Burning | Soothes Genital Herpes & Genital Discomfort

8

Herstat GST Genital Sore Treatment | Fast, Effective Relief from The Symptoms of Genital Herpes

9

Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing, Original Gel Formula, 0.23 Oz

9.3

8.0

10

Basic Brands L-Lysine Lip Ointment with Camphor, Menthol, Vitamin A & E, 0.875 oz

9.7

9.5

9.3

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