November 6, 2025

Advertising Disclosure

10 Best folate supplements of 2025

Save up to 42% off

Best Choice

1

THORNE
THORNE - 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels* - 60 Capsules - 5-MTHF 1mg
Main highlights

Supports Cardiovascular and Nerve Health
Thorne 5-MTHF provides active folate for cardiovascular, nerve health, and methylation support.

Ideal for MTHFR Gene Mutation
Perfect for individuals with MTHFR mutation needing enhanced folate absorption.

Improves Focus and Mood
Customers praise its ability to enhance focus, mood, and overall well-being.
9.8

Exceptional

Our Rating

9.9
simple to consume

9.5
Absorbency

9.3
worth the money
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Solgar
Solgar Folate 1000 mcg, 120 Tablets - 1000 mcg Bio-active Metafolin - Vegan, Gluten Free, Dairy Free, Kosher - 120 Servings

29% Off
Main highlights

Key Features
Bioactive Solgar Folate with Metafolin L-methyfolate for heart health, nervous system support, and red blood cell formation. Vegan, non-GMO, gluten-free.

Ideal Use
Perfect for vegans seeking heart and nervous system support, those needing enhanced red blood cell production without dietary restrictions.

Customer Reviews
Most praised for its effectiveness in promoting overall well-being, with noticeable improvements in heart and nervous health.
Key specs
- Form:Capsules
- Active Ingredient:Metafolin L-methyfolate
- Bioavailability:Yes
- Dosage:N/A
- Vegan:Yes
9.7

Exceptional

Our Rating

9.5
simple to consume

9.3
worth the money

8.7
Flavor
3

Nature Made
Nature Made Folic Acid 400 mcg (665 mcg DFE), Dietary Supplement for Nervous System Function, 250 Tablets, 250 Day Supply

31% Off
Main highlights

Nervous System Support
Contains 250 tablets of 400 mcg folic acid per bottle, supporting nervous system function.

Ideal for Women
Perfect for women of childbearing age and pregnant women for developmental support.

Customer Value Praise
Praised for good value and effective packaging.
9.6

Exceptional

Our Rating

9.7
simple to consume

9.7
worth the money

9.1
Flavor
4

NOW Foods
NOW Foods Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90 Tablets

42% Off
Main highlights

Superior Bioavailability and Potency
Methylfolate, a biologically active form, enhances cell function and DNA synthesis.

Ideal for MTHFR Gene Mutation
Perfect for those needing methylfolate supplementation due to genetic mutations.

Easy to Swallow Tablets
Customers appreciate the ease of swallowing despite the tablet size.
9.3

Excellent

Our Rating

9.9
simple to consume

9.9
Absorbency

9.7
worth the money
5

Life Extension
Life Extension BioActive Folate & Vitamin B12, Promotes Heart, Brain & GI Tract Health, Non-GMO, Gluten-Free, Vegetarian, 90 Capsules
Main highlights

Key Features and Benefits
Combines bioavailable forms of folate and vitamin B12 promoting heart, brain, digestive health, and healthy DNA function.

Ideal Use Cases
Perfect for individuals seeking to support heart health, maintain healthy homocysteine levels, and enhance red blood cell production.

Customer Reviews Highlight
Most praised for its effectiveness in boosting energy levels and overall sense of well-being, as reported by satisfied customers.
9.2

Excellent

Our Rating

9.9
simple to consume

9.7
worth the money

9.5
Absorbency
See Today’s Deals & Prices
6

Doctor's BEST
Doctor's Best Fully Active Folate with Quatrefolic400 mcg, Healthy Mood, Memory, Circulation, Well-Being, 90 VC

42% Off
Main highlights

Provides Active Folate and Vitamin C
Best Fully Active Folate offers MTHF 5-methyltetrahydrofolate for DNA regulation and metabolic processes, with added Vitamin C for stability. Gluten-free, Non-GMO, Vegan.

Ideal for Immune Boost and General Well-being
Perfect for individuals needing folate supplementation, including those with low folic acid, celiac disease, and pregnant women. Small capsules are easy to swallow.

Customers Praise Small Capsule Size
Users frequently commend the ease of swallowing due to the small capsule size, making it convenient for those who struggle with larger pills.
9.0

Excellent

Our Rating

9.9
simple to consume

9.7
quality of ingredients

9.7
Absorbency
7

Triquetra Health
L Methyl Folate 15mg Plus Methyl B12 Cofactor – High Potency, Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Bioactive Forms of Vitamin B9 & B12 (60 Capsules – 60 Servings)

26% Off
Main highlights

Active Folate and B12 Support
Provides 15mg L-Methyl Folate and Methyl B12 for optimal body function.

Ideal for Mood and Energy
Perfect for enhancing mood, energy, and cognitive function.

Praised for Mood Improvement
Users report improved mood and energy levels within days.
Key specs
- Form:Calcium salt
- Active Ingredient:L Methyl folate
- Bioavailability:Immediately absorbed
- Dosage:15mg
- Vegan:N/A
8.7

Very Good

Our Rating

9.7
simple to consume

9.7
worth the money

9.7
Absorbency
8

Life Extension
Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets
Main highlights

Optimal Cognitive Support
This folate supplement supports brain health and optimal cognitive function as you age.

Ideal for MTHFR Mutation
Best for individuals with MTHFR mutation needing L-methylfolate supplementation.

Highly Effective Methylfolate
Praised for its high-quality, effective L-methylfolate form over folic acid.
Key specs
- Form:Supplement
- Active Ingredient:5-MTHF
- Bioavailability:Metabolically active form
- Dosage:1700 mcg
- Vegan:N/A
8.6

Very Good

Our Rating

9.3
simple to consume

9.3
worth the money

9.1
Flavor
9

365 by Whole Foods Market
365 by Whole Foods Market, Folic Acid 800mcg, Vegan, 250 Tablets
Main highlights

Key Features and Benefits
Specially formulated for the nutritional needs of pregnant and lactating women, enhancing overall health with essential vitamins and minerals.

Ideal Use Cases
Perfect for expectant or new mothers seeking to supplement their diet with vital nutrients for their well-being and their baby`s development.

Customer Reviews Summary
Highly praised for its effectiveness in boosting energy levels and improving overall health during pregnancy and breastfeeding.
8.5

Good

Our Rating

9.9
simple to consume

9.9
worth the money

9.9
Flavor
10

Double Wood Supplements
Methylfolate 1,000mcg, 120 Capsules (Third Party Tested Methyl Folate Supplement) Methylated Folate is a More Active Form of Folate Than Folic Acid (Non-GMO, Vegan Safe) by Double Wood
Main highlights

Bioavailable Folate
L Methyl Folate is the active form of folate, easily absorbed into the bloodstream.

Energy Support
Ideal for individuals seeking to enhance energy levels and combat fatigue.

High Quality
Praised for noticeable improvements in muscle energy consumption.
Key specs
- Form:Capsules
- Active Ingredient:L Methyl Folate
- Bioavailability:High
- Dosage:1,000MCG
- Vegan:Yes
8.4

Good

Our Rating

10 Best folate supplements of 2025

1

THORNE - 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels* - 60 Capsules - 5-MTHF 1mg

9.9

9.5

9.3

How do we rank?

How do we rank?

Analyzing top stores

2

Solgar Folate 1000 mcg, 120 Tablets - 1000 mcg Bio-active Metafolin - Vegan, Gluten Free, Dairy Free, Kosher - 120 Servings

9.5

9.3

8.7

3

Nature Made Folic Acid 400 mcg (665 mcg DFE), Dietary Supplement for Nervous System Function, 250 Tablets, 250 Day Supply

9.7

9.7

9.1

4

NOW Foods Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90 Tablets

9.9

9.9

9.7

5

Life Extension BioActive Folate & Vitamin B12, Promotes Heart, Brain & GI Tract Health, Non-GMO, Gluten-Free, Vegetarian, 90 Capsules

9.9

9.7

9.5

6

Doctor's Best Fully Active Folate with Quatrefolic400 mcg, Healthy Mood, Memory, Circulation, Well-Being, 90 VC

9.9

9.7

9.7

7

L Methyl Folate 15mg Plus Methyl B12 Cofactor – High Potency, Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Bioactive Forms of Vitamin B9 & B12 (60 Capsules – 60 Servings)

9.7

9.7

9.7

8

Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets

9.3

9.3

9.1

9

365 by Whole Foods Market, Folic Acid 800mcg, Vegan, 250 Tablets

9.9

9.9

9.9

10

Methylfolate 1,000mcg, 120 Capsules (Third Party Tested Methyl Folate Supplement) Methylated Folate is a More Active Form of Folate Than Folic Acid (Non-GMO, Vegan Safe) by Double Wood

Sign up and get exclusive special deals