9 Best flea killer for dogs of 2025

Save up to 11% off

Best Choice

1

Frontline
FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

11% Off
Main highlights

Comprehensive Flea and Tick Protection
FRONTLINE Plus kills fleas, ticks, larvae, and lice effectively.

Ideal for Large Dogs
Perfect for dogs 45 to 88 lbs., including thick coats.

Waterproof and Long-lasting
Proven waterproof even through creeks and rivers.
9.9

Exceptional

Our Rating

8.0
Simple to use

8.0
Aroma

8.0
Comfort
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Value for Money

2

Capstar
Capstar for Dogs (nitenpyram), Fast-Acting Oral Flea Treatment for Dogs Over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing in 30 Minutes, 6 Doses
Main highlights

Fast-Acting Relief
Capstar nitenpyram starts killing adult fleas in just 30 minutes.

Ideal for Quick Reinfestation Control
Perfect for dogs over 25 lbs needing fast flea treatment.

Convenient Oral Administration
Praised for easy, mess-free administration without vet prescription.
Key specs
- Dog Weight Range:25.1-125 pounds
- Form:Oral
- Flea Action:Starts killing fleas in 30 minutes
- Active Ingredient:nitenpyram
- Dosage:57 mg
9.7

Exceptional

Our Rating

8.2
Simple to use

8.0
simple to consume

8.0
Aroma
3

Veterinary Formula
Veterinary Formula Flea and Tick Spray for Dogs, 8 oz – Easy-to-Use Dog Flea Spray, Kills on Contact, Prevents Egg & Larval Development for 14 weeks
Main highlights

Kills Fleas and Ticks
Veterinary Formula Spray eliminates fleas and ticks at all life stages.

Ideal for Long-Term Protection
Offers up to 14 weeks of protection from fleas and ticks.

Praised for Effectiveness
Customers commend its ability to kill pests without harming pets.
Key specs
- Active Ingredients:pyrethrins, permethrin, Nylar
- Application Method:Spray
- Formulation Type:Spray
- Safety Information:Follow directions on bottle
- Duration of Effect:Up to 14 weeks
9.6

Exceptional

Our Rating

8.4
Simple to use

8.4
For Gentle skin

8.2
Comfort
4

PetArmor
PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Dogs Over 25 lbs, 6 Doses
Main highlights

Rapid Flea Elimination
Begins killing fleas within 30 minutes with over 90% effectiveness.

Convenient for Large Dogs
Ideal for dogs weighing 25.1 to 200 pounds, no prescription needed.

Customer Praised Fast Action
Highly praised for immediate relief and fast flea reduction.
9.3

Excellent

Our Rating

8.0
Simple to use

8.0
Sheerness

8.0
Aroma
5

Capstar
Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses
Main highlights

Fast-Acting Flea Treatment
Capstar nitenpyram starts killing adult fleas in just 30 minutes.

Ideal for Small Dogs and Puppies
Safe for dogs 4 weeks and older, weighing 2-25 pounds.

Convenient No-Prescription Solution
Easy administration with no vet prescription needed, praised by customers.
Key specs
- Dog Weight Range:2-25 pounds
- Form:Oral
- Flea Action:Starts killing in 30 minutes
- Active Ingredient:Nitenpyram
- Dosage:57 mg
9.2

Excellent

Our Rating

8.2
Simple to use

8.0
simple to consume

8.0
Comfort
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6

Vet's Best
Vet’s Best Indoor Flea and Tick Spray – Dog Flea and Tick Treatment for Home, Plant-Based Formula with Natural Oils, Kills Fleas, Eggs & Ticks on Contact, Made in USA, 32 oz
Main highlights

Natural Flea Tick Protection
Certified natural plant-based formula effectively eliminates and prevents fleas, ticks, and mosquitoes.

Versatile Application Areas
Ideal for use on dogs, carpets, and furniture without staining.

Pleasant Spearmint Scent
Customers appreciate the refreshing scent that leaves homes smelling fresh.
Key specs
- Active Ingredients:Peppermint oil, Eugenol
- Application Method:Spray directly on skin
- Formulation Type:Natural plant-based
- Safety Information:Safe for dogs 12+ weeks
- Duration of Effect:Long-lasting protection
9.1

Excellent

Our Rating

8.4
Simple to use

8.0
Aroma

8.0
worth the money
7

yumflan
Yumflan Flea Comb with Rubber Handle, Flea and Tick Combs for Dogs & Cats, Fine Tooth Dog Comb for Grooming (Purple)
Main highlights

Enhanced Comfort and Control
Features a rubber-sheathed handle for a comfortable, non-slip grip, making grooming easier and more enjoyable for pet owners.

Versatile Grooming Tool
Ideal for use on cats, dogs, and other small animals with various coat types, ensuring broad applicability.

User-Friendly Design
Praised for its ergonomic handle and gentle, effective grooming, especially appreciated by those with arthritis.
Key specs
- Usage:Cats and dogs
- Grip:Rubber-sheathed handle
- Dimensions:7 x 1.8 x 0.5 inches
- Features:Non-slip handle
- Material:Higher grade metal
9.0

Excellent

Our Rating
8

Advantus
Advantus Dog Fast Acting Oral Flea Treatment Soft Chews Dogs 23 - 110 lbs. | 7 ct.
Main highlights

Fast-Acting Flea Relief
Starts killing adult fleas within one hour of administration.

Travel-Ready Solution
Ideal for preventing flea infestations during travel or visits.

Effective Flea Control
Praised for visible results in flea reduction and relief.
Key specs
- Target Weight:23 - 110 lbs
- Active Ingredients:Imidacloprid
- Application Method:Soft chew
- Treatment Duration:Once daily
- Protection Type:Flea treatment
8.9

Very Good

Our Rating

8.7
Simple to use

8.0
Aroma

8.0
Flavor
9

TTLXBL

Dog Flea and Tick Treatment Chewable 200 Treatment Chews Natural Soft Chew Fleas Ticks Treatment Dog Oral Chewables Support Supplement Breeds and Ages Dogs Chicken Flavor
8.7

Very Good

Our Rating

9 Best flea killer for dogs of 2025

1

FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

8.0

8.0

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Capstar for Dogs (nitenpyram), Fast-Acting Oral Flea Treatment for Dogs Over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing in 30 Minutes, 6 Doses

8.2

8.0

8.0

3

Veterinary Formula Flea and Tick Spray for Dogs, 8 oz – Easy-to-Use Dog Flea Spray, Kills on Contact, Prevents Egg & Larval Development for 14 weeks

8.4

8.4

8.2

4

PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Dogs Over 25 lbs, 6 Doses

8.0

8.0

8.0

5

Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses

8.2

8.0

8.0

6

Vet’s Best Indoor Flea and Tick Spray – Dog Flea and Tick Treatment for Home, Plant-Based Formula with Natural Oils, Kills Fleas, Eggs & Ticks on Contact, Made in USA, 32 oz

8.4

8.0

8.0

7

Yumflan Flea Comb with Rubber Handle, Flea and Tick Combs for Dogs & Cats, Fine Tooth Dog Comb for Grooming (Purple)

8

Advantus Dog Fast Acting Oral Flea Treatment Soft Chews Dogs 23 - 110 lbs. | 7 ct.

8.7

8.0

8.0

9

Dog Flea and Tick Treatment Chewable 200 Treatment Chews Natural Soft Chew Fleas Ticks Treatment Dog Oral Chewables Support Supplement Breeds and Ages Dogs Chicken Flavor

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