10 Best eye ointments of 2026

Save up to 31% off

1

Systane
Systane Nighttime Lubricant Eye Ointment 3.50 g , 0.12 Oz (Pack of 3)

19% Off
Main highlights

Effective Nighttime Relief
Systane Nighttime Lubricant Eye Ointment provides soothing relief for dry eyes, ensuring comfort throughout the night.

Perfect for CPAP Users
Ideal for individuals using CPAP machines, preventing dryness caused by air exposure during sleep.

Highly Recommended by Users
Praised for its effectiveness, especially for those with severe dry eyes or incomplete eyelid closure.
9.9

Exceptional

Our Rating
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Based on millions of stores and reviews

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2

Optase
Optase HYLO Night Eye Ointment - .18 oz
Main highlights

Preservative Free Night Relief
OPTASE Hylo Night Ointment provides comfortable lubrication for dry eye relief, free from preservatives.

Ideal for Nighttime Use
Designed for overnight application to protect and lubricate eyes while sleeping.

Effective Dry Eye Relief
Customers praise its effectiveness in reducing morning dry-eye symptoms and protecting the cornea.
Key specs
- Formula:White Petrolatum, Lanolin, Light Mineral Oil
- Usage:Apply before bed
- Preservatives:Preservative free
- Hydration:Over 6 hours retention
- Dimensions:3.81 x 1.61 x 0.9 inches
9.8

Exceptional

Our Rating

9.7
Moisturizing

9.3
Comfort

8.0
Simple to use
3

Systane
Systane Nighttime Lubricant Eye Ointment 3.5g Tube
Main highlights

Long-Lasting Protection
Forms a long-lasting, protective layer on eyes while you sleep, soothing and protecting against dryness and irritation.

Ideal for Nighttime Use
Best used for nighttime relief of dry eye symptoms, providing comfort and protection as you rest.

Soothing Effect
Most praised for its soothing effect, alleviating discomfort from dry eyes effectively.
Key specs
- Formula:Preservative-free
- Usage:Nighttime
- Preservatives:None
- Hydration:Soothes and protects
- Dimensions:6 x 5 x 4 inches
9.6

Exceptional

Our Rating
4

Soothe
Soothe Preservative-Free Lubricant Eye Ointment, Nighttime Relief for Severe Dry & Irritated Eyes, Gentle for Sensitive Eyes, 0.12 Fl Oz
Main highlights

Key Features and Benefits
Moisturizes and refreshes severe dry eyes overnight with a soothing formula, containing two lubricants for long-lasting relief and comfort.

Ideal Use Cases
Perfect for individuals suffering from severe dry eyes, especially effective overnight to prevent irritation and provide relief from dryness.

Customer Reviews Highlight
Most reviews praise its effectiveness in providing significant relief from severe dryness, noting its ease of use and overnight comfort.
9.4

Excellent

Our Rating

8.2
worth the money

8.0
Simple to use
5

Soothe
Soothe Preservative-Free Lubricant Eye Ointment, Nighttime Relief for Severe Dry & Irritated Eyes, Gentle for Sensitive Eyes, 0.12 Fl Oz
Main highlights

Key Features and Benefits
Moisturizes and refreshes severe dry eyes overnight with a soothing formula, containing two lubricants for long-lasting relief and comfort.

Ideal Use Cases
Perfect for individuals suffering from severe dry eyes, especially effective overnight to prevent irritation and provide relief from dryness.

Customer Reviews Highlight
Most reviews praise its effectiveness in providing significant relief from severe dryness, noting its ease of use and overnight comfort.
9.2

Excellent

Our Rating

8.2
worth the money

8.0
Simple to use
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6

Stye
Stye Sterile Lubricant Eye Ointment, Opthalmologist Tested to Relieve Stinging, Burning, Itching and Dry Eyes, 0.125 Oz

27% Off
Main highlights

Dual-Action Relief and Lubrication
Provides symptomatic stye relief and lubrication to prevent further irritation.

Ideal for Stye Treatment
Perfect for relieving discomfort from styes, including burning and itching.

Trusted Stye Relief
Praised for easing pain with quick, effective results.
Key specs
- Use Case:Stye treatment relief
- Relief Duration:Temporarily relieves discomfort
- Eye Comfort:Relieves burning, stinging, itching
- Packaging Type:Ointment
- Moisturizing Formula:Dual-action formula
9.0

Excellent

Our Rating

8.0
Comfort

8.0
Simple to use

8.0
worth the money
7

Stye
Stye Sterile Lubricant Eye Ointment, Opthalmologist Tested to Relieve Stinging, Burning, Itching and Dry Eyes, 0.125 Oz

31% Off
Main highlights

Dual-Action Relief and Lubrication
Provides symptomatic stye relief and lubrication to prevent further irritation.

Ideal for Stye Treatment
Perfect for relieving discomfort from styes, including burning and itching.

Trusted Stye Relief
Praised for easing pain with quick, effective results.
Key specs
- Use Case:Stye treatment relief
- Relief Duration:Temporarily relieves discomfort
- Eye Comfort:Relieves burning, stinging, itching
- Packaging Type:Ointment
- Moisturizing Formula:Dual-action formula
8.8

Very Good

Our Rating

8.0
Comfort

8.0
Simple to use

8.0
worth the money
8

Genteal
Genteal Tears Night-Time Ointment 3.5g Clear 0.12 Fl Oz
Main highlights

Severe Dry Eye Symptom Relief
Provides long-lasting nighttime relief, moisturizes and lubricates eyes, and protects against further eye irritation.

Nighttime Use for Maximum Effectiveness
Ideal for severe dry eyes, Bell's Palsy, Sjogren syndrome, and post-eye surgery care. Apply before bed for best results.

Thick and Soothing Formula
Praised for its thick, soothing consistency that provides overnight comfort and prevents eye irritation and dryness.
8.7

Very Good

Our Rating

9.9
Moisturizing

9.3
worth the money

8.0
Simple to use
9

Genteal
Genteal Tears Night-Time Ointment 3.5g Clear 0.12 Fl Oz
Main highlights

Severe Dry Eye Symptom Relief
Provides long-lasting nighttime relief, moisturizes and lubricates eyes, and protects against further eye irritation.

Nighttime Use for Maximum Effectiveness
Ideal for severe dry eyes, Bell's Palsy, Sjogren syndrome, and post-eye surgery care. Apply before bed for best results.

Thick and Soothing Formula
Praised for its thick, soothing consistency that provides overnight comfort and prevents eye irritation and dryness.
8.6

Very Good

Our Rating

9.9
Moisturizing

9.3
worth the money

8.0
Simple to use
10

Optase
Optase HYLO Night Eye Ointment - .18 oz

10% Off
Main highlights

Preservative Free Night Relief
OPTASE Hylo Night Ointment provides comfortable lubrication for dry eye relief, free from preservatives.

Ideal for Nighttime Use
Designed for overnight application to protect and lubricate eyes while sleeping.

Effective Dry Eye Relief
Customers praise its effectiveness in reducing morning dry-eye symptoms and protecting the cornea.
Key specs
- Formula:White Petrolatum, Lanolin, Light Mineral Oil
- Usage:Apply before bed
- Preservatives:Preservative free
- Hydration:Over 6 hours retention
- Dimensions:3.81 x 1.61 x 0.9 inches
8.5

Good

Our Rating

9.7
Moisturizing

9.3
Comfort

8.0
Simple to use

10 Best eye ointments of 2026

1

Systane Nighttime Lubricant Eye Ointment 3.50 g , 0.12 Oz (Pack of 3)

How do we rank?

How do we rank?

Analyzing top stores

2

Optase HYLO Night Eye Ointment - .18 oz

9.7

9.3

8.0

3

Systane Nighttime Lubricant Eye Ointment 3.5g Tube

4

Soothe Preservative-Free Lubricant Eye Ointment, Nighttime Relief for Severe Dry & Irritated Eyes, Gentle for Sensitive Eyes, 0.12 Fl Oz

8.2

8.0

5

Soothe Preservative-Free Lubricant Eye Ointment, Nighttime Relief for Severe Dry & Irritated Eyes, Gentle for Sensitive Eyes, 0.12 Fl Oz

8.2

8.0

6

Stye Sterile Lubricant Eye Ointment, Opthalmologist Tested to Relieve Stinging, Burning, Itching and Dry Eyes, 0.125 Oz

8.0

8.0

8.0

7

Stye Sterile Lubricant Eye Ointment, Opthalmologist Tested to Relieve Stinging, Burning, Itching and Dry Eyes, 0.125 Oz

8.0

8.0

8.0

8

Genteal Tears Night-Time Ointment 3.5g Clear 0.12 Fl Oz

9.9

9.3

8.0

9

Genteal Tears Night-Time Ointment 3.5g Clear 0.12 Fl Oz

9.9

9.3

8.0

10

Optase HYLO Night Eye Ointment - .18 oz

9.7

9.3

8.0

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