10 Best eye lubricant drops preservative frees of 2025

Save up to 30% off

Best Choice

1

Systane
Systane Ultra Lubricant Eye Drops, 60 Count (Pack of 1), (Packaging may vary)
Main highlights

Extended Protection and Fast Relief
Systane Ultra provides extended protection and fast, long-lasting relief for dry eye symptoms.

Ideal for Winter Dryness
Perfect for combating winter dryness and environmental irritants, especially in harsh climates.

Praised for Soothing Hydration
Customers love its soothing and hydrating properties, ideal for chronic dry eyes.
Key specs
- Use Case:Dry eye relief
- Relief Duration:Fast Long-Lasting
- Eye Comfort:Dry Eye Symptom Relief
- Moisturizing Formula:Extended Protection
- Preservative Free:N/A
9.8

Exceptional

Our Rating

9.5
Moisturizing

9.3
Long life

8.9
worth the money
How do we rank?

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Value for Money

2

Systane
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)

27% Off
Main highlights

Fast Hydration and Long-Lasting Relief
Provides quick hydration and sustained relief for dry eyes.

Ideal for Contact Lens Wearers
Safe for use with all contact lenses, perfect for daily wear.

User-Friendly Bottle Design
Customers appreciate the easy-to-use bottle, despite some dispensing issues.
Key specs
- Formula:Contains hyaluronate
- Usage:Safe with contact lenses
- Preservatives:Preservative free
- Hydration:Advanced hydration
- Content:1.45 ounces
9.7

Exceptional

Our Rating

9.3
Moisturizing

8.7
worth the money

8.0
Simple to use
3

Systane
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)
Main highlights

Fast Acting Hydration
Nano droplets provide quick and effective moisture for sensitive eyes.

Ideal for Post-Lasik
Recommended for use before and after Lasik surgery for optimal recovery.

Improved Bottle Design
New squeeze bottle retains shape and reduces waste, praised by users.
9.6

Exceptional

Our Rating

9.1
Long life

9.1
Moisturizing

8.2
worth the money
4

Systane
Systane Ultra Multi-Dose Preservative-Free Eye Drops Twin Pack (2x10ml)

28% Off
Main highlights

Preservative-Free Hydration
Fast-acting hydration with a preservative-free formula for sensitive eyes, providing lasting dry eye relief.

Ideal for Screen Users
Perfect for users experiencing dry eyes from prolonged screen time or contact lens wear.

Highly Effective Relief
Customers praise its effectiveness in soothing dry and irritated eyes despite the bottle design.
Key specs
- Use Case:dry eye symptom relief
- Relief Duration:lasting dry eye relief
- Eye Comfort:for sensitive eyes
- Moisturizing Formula:Moisture rich formula
- Preservative Free:Preservative-Free
9.5

Excellent

Our Rating
5

Refresh
Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free,Value Size, 0.01 Fl Oz Single-Use Containers, 70 Count

30% Off
Main highlights

Preservative-Free Comfort
Original strength, preservative-free formula ideal for sensitive eyes.

Post-Surgery Relief
Effective for dryness relief after LASIK or cataract surgery.

Single-Use Convenience
Praised for sterile, single-use vials reducing contamination risk.
Key specs
- Use Case:After LASIK or surgeries
- Relief Duration:Instantly moisturizes
- Eye Comfort:Great for sensitive eyes
- Moisturizing Formula:Preservative-free formula
- Preservative Free:Yes
9.3

Excellent

Our Rating

9.9
Simple to use

9.3
worth the money
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6

Refresh

Refresh Tears PF Preservative-Free Artificial Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)
9.0

Excellent

Our Rating
7

Refresh
Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

18% Off
Main highlights

Fast-Acting Relief
Rapidly comforts dry, irritated eyes with a triple-action formula.

Ideal for On-the-Go
Single-use vials are convenient for travel and frequent use.

Praised for Immediate Relief
Customers love the quick relief from dryness and irritation.
8.9

Very Good

Our Rating

9.9
Simple to use

9.3
Moisturizing

8.9
Long life
8

Systane

Systane PRO PF Multi-dose Preservative-Free Lubricant Eye Drops 2 Count

27% Off
8.8

Very Good

Our Rating
9

Refresh
Refresh Celluvisc Lubricant Eye Gel For Dry Eyes, Preservative-Free Drops, 0.01 Fl Oz Single-Use Containers, 30 Count

30% Off
Main highlights

Relieves Dry and Irritated Eyes
Original strength gel formula alleviates discomfort and keeps eyes feeling better longer.

Ideal for Nighttime Use
Recommended for evening use due to its thick, moisturizing formula.

Highly Praised for Moisturizing
Customers praise its effectiveness in keeping eyes hydrated overnight.
Key specs
- Use Case:Alleviates discomfort
- Relief Duration:Keeps eyes feeling better longer
- Eye Comfort:Relieves dry, burning, irritated eyes
- Moisturizing Formula:Original strength gel
- Preservative Free:N/A
8.6

Very Good

Our Rating

9.1
Simple to use

9.1
Comfort

8.9
Moisturizing
10

Refresh
Refresh Optive Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count

28% Off
Main highlights

Dual-Action Lubrication and Hydration
The dual-action formula lubricates and hydrates, providing fast relief from mild eye dryness with soothing moisture.

Ideal for Post-Surgery and Sensitive Eyes
Perfect for use after LASIK or other eye surgeries; preservative-free for sensitive eyes.

Highly Praised for Soothing Effectiveness
Customers rave about the soothing and moisturizing effects, especially for computer users and those with severe dry eyes.
Key specs
- Use Case:Post-surgery dryness
- Relief Duration:Works fast
- Eye Comfort:Soothing moisture
- Moisturizing Formula:Dual-action formula
- Preservative Free:Yes
8.3

Good

Our Rating

9.9
For traveling

9.7
Comfort

9.3
Moisturizing

10 Best eye lubricant drops preservative frees of 2025

1

Systane Ultra Lubricant Eye Drops, 60 Count (Pack of 1), (Packaging may vary)

9.5

9.3

8.9

How do we rank?

How do we rank?

Analyzing top stores

2

Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)

9.3

8.7

8.0

3

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)

9.1

9.1

8.2

4

Systane Ultra Multi-Dose Preservative-Free Eye Drops Twin Pack (2x10ml)

5

Refresh Plus Lubricant Eye Drops For Dry Eyes, Preservative-Free,Value Size, 0.01 Fl Oz Single-Use Containers, 70 Count

9.9

9.3

6

Refresh Tears PF Preservative-Free Artificial Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)

7

Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

9.9

9.3

8.9

8

Systane PRO PF Multi-dose Preservative-Free Lubricant Eye Drops 2 Count

9

Refresh Celluvisc Lubricant Eye Gel For Dry Eyes, Preservative-Free Drops, 0.01 Fl Oz Single-Use Containers, 30 Count

9.1

9.1

8.9

10

Refresh Optive Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count

9.9

9.7

9.3

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