10 Best ergonomic gaming mice of 2025

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Best Choice

1

Logitech
Logitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite

17% Off
Main highlights

Ergonomic Design Benefit
The 57-degree angle reduces wrist strain and improves posture.

Ideal for Multi-Device Use
Perfect for users who switch between Windows and Apple computers.

Praised for Comfort
Users love the natural grip and reduced muscle strain.
Key specs
- Design:Natural handshake position
- Battery:1 Lithium Polymer
- Dimensions:4.72 x 3.11 x 3.09 inches
- Connectivity:802.11a
- Features:Advanced optical tracking
9.8

Exceptional

Our Rating

9.5
Battery Duration

9.3
lasts a long time

9.3
materials Quality
How do we rank?

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Value for Money

2

Logitech
Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Right Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop, PC - Graphite

11% Off
Main highlights

Ergonomic Comfort
Designed for small to medium hands, promotes natural posture.

Versatile Connectivity
Connects via Bluetooth or USB to multiple operating systems.

Quiet Clicks
Praised for its whisper-quiet operation, ideal for offices.
9.7

Exceptional

Our Rating

9.7
worth the money

9.7
Battery Duration

9.3
Comfortable
3

Razer
Razer Basilisk V3 Customizable Ergonomic Gaming Mouse: Fastest Gaming Mouse Switch - Chroma RGB Lighting - 26K DPI Optical Sensor - 11 Programmable Buttons - HyperScroll Tilt Wheel - Classic Black

42% Off
Main highlights

Ergonomic Design with Thumb Rest
Supports hand comfortably with optimally positioned buttons for easy access.

Versatile Gaming and Office Use
Ideal for FPS gaming and office tasks with customizable buttons and ergonomic design.

Praised Hyperscroll Tilt Wheel
Highly appreciated for smooth scrolling and tactile feedback.
Key specs
- Design:Ergonomic with thumb rest
- Backlight:11 Razer Chroma RGB zones
- Buttons:11 programmable
- DPI:26K
- Battery:1 Lithium Ion required
9.5

Excellent

Our Rating

9.5
Precision

9.5
Comfort

9.3
Comfortable
4

ProtoArc
ProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for Windows, Mac OS, Black
Main highlights

Ergonomic Design Benefit
Features an extended wrist rest for natural forearm position, reducing fatigue.

Multi-Device Usability
Ideal for multitasking with dual Bluetooth and USB connectivity across devices.

Customer Praised Comfort
Highly praised for its ergonomic comfort and design efficiency.
Key specs
- Design:Ergonomic, Wireless
- Battery:500mAh Li-Ion
- Dimensions:5.43 x 2.72 x 0.1 inches
- Connectivity:Dual BT 4.0, 2.4G USB
- Features:Silent Clicking, Rechargeable
9.4

Excellent

Our Rating
5

Nulea
Nulea M504 Wired Vertical Mouse, USB Ergonomic Optical Mouse with 4 Adjustable DPI, 11 RGB Backlight Modes, Compatible for Laptop, PC, Desktop, Mac, Grey

10% Off
Main highlights

Ergonomic Design Benefits
Reduces arm discomfort and wrist pain with natural grip.

Ideal for Office Use
Perfect for long hours of work, reducing strain.

Praised RGB Lighting
Users love the adjustable and vibrant RGB lighting.
Key specs
- Design:57 degree ergonomic vertical
- Battery:1 Lithium Ion required
- Dimensions:4.61 x 3.46 x 3.43 inches
- Connectivity:USB 2.0
- Features:RGB lighting, non-slip scroll
9.2

Excellent

Our Rating

9.9
worth the money

9.9
Comfort

9.9
Comfortable
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6

Perixx

Perixx PERIMICE-713RX Wireless Rechargeable Vertical Mouse - Duo Wired and Wireless Charging Feature - Charging Pad Included - 6 Buttons Design - Black - Right-Handed Design
9.1

Excellent

Our Rating
7

TRELC
TRELC Gaming Mouse with 5 D Rocker, Ergonomic Mouse with 10000 DPI/11 Programmable Buttons, Vertical Gaming Mice Wired for PC/Laptop/E-Sports/Gamer (Black)
Main highlights

Ergonomic Design Benefits
Reduces wrist strain and muscle pain with vertical grip.

Ideal for Gaming Enthusiasts
Perfect for FPS, MOBA, and MMO gamers with 5-direction rocker.

Praised Comfort and Wrist Relief
Highly comfortable for small hands, eases wrist fatigue.
9.0

Excellent

Our Rating

9.3
Precision

8.9
Comfortable

8.7
materials Quality
8

Redragon
Redragon M908 Impact RGB LED MMO Gaming Mouse with 12 Side Buttons, Optical Wired Ergonomic Mouse with Max 12,400DPI, High Precision, 18 Programmable Macro Shortcuts, Comfort Grip

30% Off
Main highlights

High Precision and Customization
Features up to 12,400 DPI, adjustable in 100 increments.

Ideal for MMO Gaming
Equipped with 12 programmable side buttons for complex commands.

Highly Praised Comfort
Users appreciate ergonomic design for comfort during extended use.
8.8

Very Good

Our Rating

9.1
Simple to use

8.9
Comfortable

8.9
for playing video games
9

Razer
Razer Basilisk V3 X HyperSpeed Customizable Wireless Gaming Mouse: Mechanical Switches Gen-2-5G Advanced 18K Optical Sensor - Chroma RGB 9 Programmable Controls 535 Hr Battery Classic Black

37% Off
Main highlights

Ergonomic Design with Custom Controls
The iconic ergonomic form supports various grips with 9 customizable buttons for personalized commands.

Ideal for Long Gaming Sessions
Up to 285 hours on HyperSpeed, 535 hours on Bluetooth, perfect for extended play.

Praised for Smooth Performance
High-resolution sensor praised for precision and smooth operation without noticeable lag.
Key specs
- Design:Ergonomic
- Backlight:Razer Chroma RGB
- Buttons:9 customizable
- DPI:18K
- Battery:1 AA required
8.7

Very Good

Our Rating
10

Redragon
Redragon M811 Aatrox MMO Gaming Mouse, 15 Programmable Buttons Wired RGB Mouse w/Ergonomic Natural Grip Build, 10 Side Macro Keys, Software Supports DIY Keybinds & Backlit
Main highlights

Customizable DPI and Button Options
Offers 5 DPI levels and 15 programmable buttons for gaming versatility.

Ideal for MMO Gamers
Perfect for MMO players needing multiple keybinds and macros.

Praised Button Layout
Users love the accessible and well-spaced button design.
Key specs
- Design:Natural grip
- Backlight:5 modes RGB
- Buttons:15 programmable
- DPI:500-12400
- Battery:N/A
8.6

Very Good

Our Rating

10 Best ergonomic gaming mice of 2025

1

Logitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite

9.5

9.3

9.3

How do we rank?

How do we rank?

Analyzing top stores

2

Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Right Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop, PC - Graphite

9.7

9.7

9.3

3

Razer Basilisk V3 Customizable Ergonomic Gaming Mouse: Fastest Gaming Mouse Switch - Chroma RGB Lighting - 26K DPI Optical Sensor - 11 Programmable Buttons - HyperScroll Tilt Wheel - Classic Black

9.5

9.5

9.3

4

ProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for Windows, Mac OS, Black

5

Nulea M504 Wired Vertical Mouse, USB Ergonomic Optical Mouse with 4 Adjustable DPI, 11 RGB Backlight Modes, Compatible for Laptop, PC, Desktop, Mac, Grey

9.9

9.9

9.9

6

Perixx PERIMICE-713RX Wireless Rechargeable Vertical Mouse - Duo Wired and Wireless Charging Feature - Charging Pad Included - 6 Buttons Design - Black - Right-Handed Design

7

TRELC Gaming Mouse with 5 D Rocker, Ergonomic Mouse with 10000 DPI/11 Programmable Buttons, Vertical Gaming Mice Wired for PC/Laptop/E-Sports/Gamer (Black)

9.3

8.9

8.7

8

Redragon M908 Impact RGB LED MMO Gaming Mouse with 12 Side Buttons, Optical Wired Ergonomic Mouse with Max 12,400DPI, High Precision, 18 Programmable Macro Shortcuts, Comfort Grip

9.1

8.9

8.9

9

Razer Basilisk V3 X HyperSpeed Customizable Wireless Gaming Mouse: Mechanical Switches Gen-2-5G Advanced 18K Optical Sensor - Chroma RGB 9 Programmable Controls 535 Hr Battery Classic Black

10

Redragon M811 Aatrox MMO Gaming Mouse, 15 Programmable Buttons Wired RGB Mouse w/Ergonomic Natural Grip Build, 10 Side Macro Keys, Software Supports DIY Keybinds & Backlit

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