Our rankings are generated through the algorithmic analysis of thousands of customer reviews about products, brands, merchant customer service levels, popularity trends, and more. We use advanced technology, including AI, to help process and organize this information at scale, supporting our analysis with greater speed and consistency. The rankings reflect our opinion and should be a good starting point for shopping.
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10 Best enzyme urine cleaners of 2026
Save up to 22% off
Best Choice1
Bioda9.9Exceptional
397+
bought this week
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer, 1 Gallon
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Type:Probiotic Enzyme Cleaner and Deodorizer
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Use Duration:Active up to 21 days
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Bottle Size:1 Gallon
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Formulation:Professional Strength
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Fragrance:Lemon and sage
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Value for Money2
Nature's Miracle9.7Exceptional
Nature's Miracle Cat Urine Destroyer Plus, Enzymatic Cleaner, 32 oz
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package dimensions:10.55 x 4.67 x 2.76 inches; 2.29 Pounds
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asin:B09KQTY9YR
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date first available:October 31, 2021
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item model number:P-98367
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best sellers rank:#1 in Cat Stain Removers
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3
Nature's Miracle9.5Excellent
Nature's Miracle Dog Urine Destroyer Plus, Enzymatic Cleaner, 32 oz
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product dimensions:4.53 x 2.95 x 10.43 inches; 2.27 Pounds
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asin:B09KQVCC67
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date first available:October 31, 2021
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department:Unisex-Adult
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item model number:P-98366
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4
Biokleen9.4Excellent
Biokleen Bac Out Enzyme Cleaner, Stain & Pet Odor Eliminator, Lime Scent
22% Off-
is discontinued by manufacturer:No
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product dimensions:7 x 12 x 7 inches; 0.01 ounces
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asin:B0061VZQWO
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date first available:April 6, 2011
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item model number:B00034
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5
Nature's Miracle9.2Excellent
Nature’s Miracle Dog Stain & Odor Remover, Enzymatic Cleaner, 24 oz
18% Off-
product dimensions:3.75 x 2 x 11 inches; 1.67 Pounds
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asin:B0717BLT6V
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date first available:May 30, 2017
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department:Unisex-Adult
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item model number:P-96962-6
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6
Zep8.9Very Good
Zep Urine Remover 128 Ounces Targets and Eliminates Urine Odors and Stains
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asin:B0CK2M9LQ2
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product dimensions:12.5 x 6 x 6 inches; 8.65 Pounds
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date first available:September 28, 2023
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item model number:ZUURMV128
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best sellers rank:#10 in Commercial All-Purpose Cleaners
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7
Nature's Miracle8.6Very Good
Nature's Miracle Cat Urine Destroyer Plus, Enzymatic Cleaner, 1 gal
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8
AmazonCommercial8.5Good
AmazonCommercial Multi-Purpose Enzyme Cleaner, Stain & Odor Remover, Pet Stain Remover, 1-Gallon, 1-Pack
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Rocco & Roxie Supply Co.8.4Good
Rocco & Roxie Enzyme Stain & Odor Eliminator, 1 Gallon
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Form Factor:Spray
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Certified Safe:Seal of Approval by the Carpet and Rug Institute (CRI)
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Capacity:1-Gallon
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Cleaner Type:Enzyme Cleaner
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Ingredients:Chlorine free, color safe, no hazardous propellants or residue
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10
Nilodor8.2Good
Nilodor BEON Urine Enzymatic Cleaner with Odor Neutralizer for Pet Dog, Carpet, and Bathroom, 1 Gallon, Cucumber Melon
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is discontinued by manufacturer:No
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product dimensions:1 x 1 x 1 inches 8.71 Pounds
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country of origin:China
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asin:B0113ZHXM8
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date first available:July 2, 2015
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