Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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10 Best enzyme urine cleaners of 2026
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Best Choice1
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in the last weekRocco & Roxie Supply Co.9.7Exceptional
Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon
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Form Factor:Spray
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Certified Safe:Seal of Approval by the Carpet and Rug Institute (CRI)
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Capacity:1-Gallon
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Cleaner Type:Enzyme Cleaner
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Ingredients:Chlorine free, color safe, no hazardous propellants or residue
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Value for Money2
Eco Strong9.5Excellent
Eco Strong Pet Stain and Odor Remover - Cat Urine Enzyme Cleaner Destroyer, Urine Destroyer for Dogs, Pet Urine Enzyme Cleaner - 128 Oz
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package dimensions:12.4 x 6.02 x 5.83 inches 8 Pounds
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asin:B083FBGDJM
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date first available:January 17, 2020
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item model number:pet-beds
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best sellers rank: 63 in Cat Odor Removers
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3
Rocco & Roxie Supply Co.9.4Excellent
Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz
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4
Bioda9.3Excellent
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
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package dimensions:11.85 x 6.02 x 5.91 inches; 9.22 Pounds
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asin:B0CJ51KCH4
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date first available:September 15, 2023
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best sellers rank:#3 in Commercial All-Purpose Cleaners
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product dimensions:N/A
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5
Biokleen9.0Excellent
Biokleen Bac-Out Enzyme Cleaner and Stain & Odor Remover for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic, Lime Scent, 128 Ounces
33% Off Limited Time Deal-
is discontinued by manufacturer:No
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product dimensions:7 x 12 x 7 inches; 0.01 ounces
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asin:B0061VZQWO
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date first available:April 6, 2011
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item model number:B00034
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6
Nature's Miracle8.8Very Good
Nature’s Miracle Urine Destroyer Plus for Cats, Enzymatic Formula Tough on Strong Cat Urine And The Yellow Sticky Residue, 1 Gal
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country of origin:USA
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package dimensions:12.24 x 7.6 x 5 inches 8.84 Pounds
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asin:B09KQXK6WQ
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date first available:October 31, 2021
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item model number:P-98372
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7
Rocco & Roxie Supply Co.8.7Very Good
Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training
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8
AmazonCommercial8.6Very Good
AmazonCommercial Multi-Purpose Enzyme Cleaner, Stain & Odor Remover, Pet Stain Remover, 1-Gallon, 1-Pack
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package dimensions:N/A
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asin:B07XL3C6FR
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date first available:January 6, 2020
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best sellers rank:#4 in Commercial All-Purpose Cleaners
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product dimensions:6.1 x 6.1 x 11.68 inches; 8.6 Pounds
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Black Diamond Stoneworks8.5Good
Commercial Multi-Purpose Enzyme Cleaner & Odor Eliminator | Pet & Human Urine, Stains & Odors | Carpet, Laundry, Bathroom, Drain & Trash Deodorizer | Dog, Cat, Organic Waste Remover (1 Gallon)
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10
GELEAN8.4Good
Multi-Purpose Probiotic Enzyme Citrus Cleaner, 1/2 Gallon (64 oz.) - Pet Stain and Odor Remover - Concentrated - Professional & Home Strength Drains, Floors, Bathrooms, Toilets Trash Can, Made in USA
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