9 Best enzyme pet urine removers of 2025

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Editor's Choice

1

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ANGRY ORANGE
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies
Main highlights

Dual Action Enzyme Cleaner
Combines stain removal and odor elimination for pet messes.

Versatile Multi-Surface Use
Ideal for carpets, hardwood, fabrics, and more.

Citrus Scented Success
Customers praise the effective odor removal and pleasant scent.
9.8

Exceptional

Our Rating

9.3
Simple to use

8.9
Aroma

8.7
Odor elimination
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Value for Money

2

Biokleen
Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic
Main highlights

Eco-Friendly Formula
Bac-Out uses a plant-based, biodegradable formula without harsh chemicals.

Versatile Cleaning Use
Ideal for pet accidents, laundry, carpets, and more.

Effective Odor Removal
Customers praise its ability to eliminate odors effectively.
9.7

Exceptional

Our Rating

9.7
Simple to use

9.5
Aroma

9.5
Odor elimination
3

Bioda
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
Main highlights

Powerful Cleaning and Odor Control
This probiotic cleaner offers powerful cleaning and odor elimination for various surfaces, leaving a fresh lemon and sage scent.

Ideal for Pet and Household Use
Perfect for managing pet stains, odors, and maintaining household cleanliness, especially in bathrooms and kitchens.

Highly Effective Odor Elimination
Customers praise its ability to permanently eliminate tough odors, especially from pet-related incidents and organic waste.
Key specs
- volume:1 Gallon
- cleaning method:Probiotic cleaner
- scent:Lemon and sage
- specific instructions:Spray & let probiotics work
- perfume:Lemon and sage
9.6

Exceptional

Our Rating
4

Nature's Miracle
Nature’s Miracle Urine Destroyer Plus Dog, 32 Ounces, Enzymatic Formula, Ready-to-Use
Main highlights

Powerful_Enzymatic_Cleaning
Begins breaking down stains immediately and continues until bio-mess is gone.

Versatile_Use_Scenarios
Ideal for multi-pet households, effective on carpets, floors, and fabrics.

Customer_Praised_Sprayer
Battery-powered sprayer offers ease and precision in application.
Key specs
- Enzymatic Formula:Continues working on bio-mess
- Usage:Dog urine messes
- Dimensions:10.51 x 4.61 x 2.76 inches
- Features:Safe for pets and home
- Odor Control:Breaks down odor
9.4

Excellent

Our Rating

9.7
potty training

8.9
Odor elimination

8.7
Simple to use
5

KIDS 'N' PETS
KIDS 'N' PETS Instant All-Purpose Stain & Odor Remover Permanently Eliminates Dog Pee, Cat Urine, Other Smells, Spots from Home Carpet, Couch, Furniture, Mattress, Fabric. Non-Toxic, Child Safe - 27oz
Main highlights

Neutralizes Odors and Stains
Patented formula effectively neutralizes and eliminates tough odors and stains, ensuring a deep clean.

Versatile Application
Ideal for use on carpets, furniture, bedding, and any water-safe surfaces.

Highly Effective Odor Removal
Praised for exceptional ability to permanently eliminate urine and other odors.
Key specs
- Usage:Household stains & odors
- Formulation:Patented formula
- Surface Compatibility:Carpet, furniture, mattresses
- Stain Remover:Instant All-purpose
- Special Features:Non-Toxic & Cruelty-Free
9.3

Excellent

Our Rating

9.9
Stain resistance

9.5
Simple to use

9.1
worth the money
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6

KINZUA ENVIRONMENTAL
KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Effective on Laundry, Carpets & More, Original Scent, 1 Gallon

26% Off
Main highlights

High Enzyme Count for Effective Cleaning
Contains over 200 billion enzymes to liquefy, digest, and eliminate urine and feces.

Versatile Applications for Pet Owners
Ideal for carpets, upholstery, laundry, drains, and toilets; perfect for households with pets.

Customer Praised Stain and Odor Removal
Highly effective in removing pet stains and odors, leaving carpets smelling fresh.
9.0

Excellent

Our Rating

9.1
Simple to use

8.9
Odor elimination

8.4
Aroma
7

ACTIVE
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

20% Off
Main highlights

Complete Odor and Stain Elimination
The enzyme-based formula effectively removes pet stains and odors, leaving a pleasant citrus scent.

Versatile Home Use
Ideal for cleaning carpets, upholstery, hardwood, and various home surfaces affected by pet messes.

Highly Praised Citrus Scent
Customers appreciate the non-overpowering citrus scent that effectively neutralizes odors.
Key specs
- size:32oz
- material:Enzymes and Natural Probiotics
- function:Odor and stain removal
- dimensions:10.2 x 4.65 x 2.83 inches
- color:N/A
8.9

Very Good

Our Rating
8

OUT!
OUT! PetCare Stain and Odor Remover Spray for Pets – Enzyme Cleaner for Carpet, Rugs, and Floors – Dog and Cat Urine Eliminator and Deodorizer – Made in USA – 32 fl oz Bottles, 2 Pack
Main highlights

Key Features
Powerful 3x Pro-Bacteria and Enzyme formula, patented 3-in-1 sprayer, certified cleaner that also eliminates odors for a comprehensive clean.

Ideal Use Cases
Perfect for removing tough stains and everyday messes from carpets, bedding, and other water-safe surfaces, especially in homes with pets.

Customer Praise
Reviewers consistently highlight its effectiveness in eliminating stubborn stains and odors, praising its reliability for a fresh and clean home environment.
Key specs
- Usage:Tackle tough stains
- Formulation:3x Pro-Bacteria and Enzyme
- Surface Compatibility:Carpets, bedding, water-safe surfaces
- Stain Remover:3x Pro-Bacteria and Enzyme
- Special Features:Patented 3-in-1 sprayer
8.8

Very Good

Our Rating

9.3
Simple to use

9.1
Odor elimination

8.9
worth the money
9

Simple Solution
Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz
Main highlights

Powerful Enzymatic Formula
Three times stronger than regular formulas, effectively removes tough pet stains and odors.

Versatile Home Use
Ideal for cleaning dog and cat urine, feces, vomit on carpets, upholstery, and more.

Highly Praised Sprayer
Customers love the improved sprayer for its fine mist and no leakage.
8.7

Very Good

Our Rating

9.7
Odor elimination

9.3
Comfort

9.1
deep clean

9 Best enzyme pet urine removers of 2025

1

Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

9.3

8.9

8.7

How do we rank?

How do we rank?

Analyzing top stores

2

Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic

9.7

9.5

9.5

3

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

4

Nature’s Miracle Urine Destroyer Plus Dog, 32 Ounces, Enzymatic Formula, Ready-to-Use

9.7

8.9

8.7

5

KIDS 'N' PETS Instant All-Purpose Stain & Odor Remover Permanently Eliminates Dog Pee, Cat Urine, Other Smells, Spots from Home Carpet, Couch, Furniture, Mattress, Fabric. Non-Toxic, Child Safe - 27oz

9.9

9.5

9.1

6

KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Effective on Laundry, Carpets & More, Original Scent, 1 Gallon

9.1

8.9

8.4

7

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

8

OUT! PetCare Stain and Odor Remover Spray for Pets – Enzyme Cleaner for Carpet, Rugs, and Floors – Dog and Cat Urine Eliminator and Deodorizer – Made in USA – 32 fl oz Bottles, 2 Pack

9.3

9.1

8.9

9

Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz

9.7

9.3

9.1

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