10 Best enzyme pet urine removers of 2025

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Editor's Choice

1

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ANGRY ORANGE
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies
Main highlights

Dual Action Enzyme Cleaner
Combines stain removal and odor elimination for pet messes.

Versatile Multi-Surface Use
Ideal for carpets, hardwood, fabrics, and more.

Citrus Scented Success
Customers praise the effective odor removal and pleasant scent.
9.8

Exceptional

Our Rating

9.3
Simple to use

8.9
Aroma

8.7
Odor elimination
How do we rank?

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
Value for Money

2

Eco Strong
Eco Strong Pet Stain and Odor Remover - Cat Urine Enzyme Cleaner Destroyer, Urine Destroyer for Dogs, Pet Urine Enzyme Cleaner - 128 Oz
Main highlights

Key Features
Bio-enzymatic formula eliminates odors at the source, not just masking them. Safe, non-toxic, and has a gentle citrus scent.

Ideal Use Cases
Perfect for cleaning carpets, upholstery, car interiors, and laundry affected by pet accidents. Ideal for homes with pets.

Customer Praise
Most reviews highlight its effectiveness in removing stubborn pet odors and stains, leaving a fresh scent without harmful chemicals.
9.6

Exceptional

Our Rating

9.9
Absorbency

9.3
Simple to clean

9.1
Odor elimination
3

KINZUA ENVIRONMENTAL
KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Effective on Laundry, Carpets & More, Original Scent, 1 Gallon
Main highlights

High Enzyme Count for Effective Cleaning
Contains over 200 billion enzymes to liquefy, digest, and eliminate urine and feces.

Versatile Applications for Pet Owners
Ideal for carpets, upholstery, laundry, drains, and toilets; perfect for households with pets.

Customer Praised Stain and Odor Removal
Highly effective in removing pet stains and odors, leaving carpets smelling fresh.
9.3

Excellent

Our Rating

9.1
Simple to use

8.9
Odor elimination

8.4
Aroma
4

Rocco & Roxie Supply Co.
Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
Main highlights

Certified Safe and Effective
Chlorine-free, color-safe, and CRI-approved for all carpets.

Ideal for Pet Owners
Perfect for removing pet stains and odors from multiple surfaces.

Enzyme-Based Miracle Worker
Customer reviews praise its ability to eliminate odors completely.
9.2

Excellent

Our Rating

9.9
worth the money

9.5
Simple to use

8.9
Odor elimination
5

Nature's Miracle
Nature's Miracle Urine Destroyer Plu for Dogs, Enzymatic Formula for Severe Dog Urine Stains, 32 fl oz

15% Off
Main highlights

Powerful_Enzymatic_Cleaning
Begins breaking down stains immediately and continues until bio-mess is gone.

Versatile_Use_Scenarios
Ideal for multi-pet households, effective on carpets, floors, and fabrics.

Customer_Praised_Sprayer
Battery-powered sprayer offers ease and precision in application.
9.0

Excellent

Our Rating

9.7
potty training

8.9
Odor elimination

8.7
Simple to use
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6

Resolve
Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz
Main highlights

Odor Neutralization and Stain Removal
Neutralizes odors on contact and removes pet and food stains.

Ideal for Households with Pets and Kids
Perfect for carpets, fabrics, and hard surfaces in busy homes.

Customer Praise for Odor Elimination
Praised for effectively reducing odors, even with repeated use.
8.9

Very Good

Our Rating

9.5
Simple to use

9.1
worth the money

8.7
Aroma
7

ACTIVE
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil
Main highlights

Complete Odor and Stain Elimination
The enzyme-based formula effectively removes pet stains and odors, leaving a pleasant citrus scent.

Versatile Home Use
Ideal for cleaning carpets, upholstery, hardwood, and various home surfaces affected by pet messes.

Highly Praised Citrus Scent
Customers appreciate the non-overpowering citrus scent that effectively neutralizes odors.
8.8

Very Good

Our Rating
8

OUT!
OUT! PetCare Advanced Pet Stain and Odor Remover, Stain and Odor Eliminator, Pet Carpet Cleaner, Enzyme Cleaner Spray, Pro Bacteria Urine Remove, Deodorizer, Safe & Effective, 32 fl oz (2 Pack)
Main highlights

Key Features
Powerful 3x Pro-Bacteria and Enzyme formula, patented 3-in-1 sprayer, certified cleaner that also eliminates odors for a comprehensive clean.

Ideal Use Cases
Perfect for removing tough stains and everyday messes from carpets, bedding, and other water-safe surfaces, especially in homes with pets.

Customer Praise
Reviewers consistently highlight its effectiveness in eliminating stubborn stains and odors, praising its reliability for a fresh and clean home environment.
8.6

Very Good

Our Rating

9.3
Simple to use

9.1
Odor elimination

8.9
worth the money
9

BugMD
BugMD Enzyme Cleaner & Odor Eliminator for Strong Odor (32oz) - Pet Stain Remover for Carpet, Upholstery, Hardwood, Dog & Cat Urine - Powerful Deodorizer for Home, Floors, Furniture, & Carpet Cleaning
Main highlights

Powerful Enzyme Formula
Removes stubborn pet stains and odors from multiple surfaces.

Versatile Home Use
Ideal for carpets, rugs, hardwood, furniture, and more.

Customer Praised Safety
Highly appreciated for being non-toxic and safe for pets.
8.5

Good

Our Rating
10

ACTIVE
Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads
Main highlights

Powerful Odor and Stain Elimination
ACTIVE Pet Detergent's enzymes tackle pet stains and odors, ensuring fresh results.

Versatile for Pet and Human Laundry
Ideal for pet beds, clothing, and even personal laundry.

Highly Praised Odor Removal
Customers love its ability to remove tough pet odors.
Key specs
- Cleaning Power:Natural cleaning power
- Load Capacity:64 loads
- Formulation:Bio based enzyme cleaner
- Hypoallergenic:Gentle for sensitive skin
- Stain Removal:Targets pesky stains
8.4

Good

Our Rating

10 Best enzyme pet urine removers of 2025

1

Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

9.3

8.9

8.7

2

Eco Strong Pet Stain and Odor Remover - Cat Urine Enzyme Cleaner Destroyer, Urine Destroyer for Dogs, Pet Urine Enzyme Cleaner - 128 Oz

9.9

9.3

9.1

3

KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Effective on Laundry, Carpets & More, Original Scent, 1 Gallon

9.1

8.9

8.4

4

Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray

9.9

9.5

8.9

5

Nature's Miracle Urine Destroyer Plu for Dogs, Enzymatic Formula for Severe Dog Urine Stains, 32 fl oz

9.7

8.9

8.7

6

Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz

9.5

9.1

8.7

7

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

8

OUT! PetCare Advanced Pet Stain and Odor Remover, Stain and Odor Eliminator, Pet Carpet Cleaner, Enzyme Cleaner Spray, Pro Bacteria Urine Remove, Deodorizer, Safe & Effective, 32 fl oz (2 Pack)

9.3

9.1

8.9

9

BugMD Enzyme Cleaner & Odor Eliminator for Strong Odor (32oz) - Pet Stain Remover for Carpet, Upholstery, Hardwood, Dog & Cat Urine - Powerful Deodorizer for Home, Floors, Furniture, & Carpet Cleaning

10

Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads

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