10 Best enzyme laundry detergents of 2025

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Best Choice

1

Rockin' Green
Rockin' Green Laundry Detergent, Plant based, All Natural Laundry Detergent Powder, Vegan and Biodegradable Odor Fighter, Safe for Sensitive Skin (Active Wear 90 Loads - Unscented)
Main highlights

Plant-Based Power
Formulated with plant-based enzymes to tackle stubborn stains and odors.

Ideal for Activewear
Perfect for high-tech workout clothes and microfibers, extending their lifespan.

Loved for Odor Elimination
Highly praised for effectively removing odors from gym clothes.
Key specs
- Cleaning Power:Powerful plant-based enzymes
- Load Capacity:Up to 90 loads
- Formulation:Plant-based enzymes
- Stain Removal:Breaks down toughest stains
- Eco-Friendly:Vegan and cruelty-free
9.9

Exceptional

Our Rating

9.5
Freshness

9.5
For Gentle skin

9.1
Aroma
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Value for Money

2

Dirty Labs
Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) | Hyper-Concentrated | High Efficiency & Standard Machine Washing | Nontoxic, Biodegradable | Stain & Odor Removal
Main highlights

Key Features
Nontoxic, biobased, hypoallergenic formula with advanced enzyme technology for effective, gentle cleaning. Eco-friendly packaging and manufacturing.

Ideal Use Cases
Perfect for sensitive skin, baby clothes, and pet bedding. Optimized for cold water and high efficiency washers.

Customer Praise
Highly praised for its stain removal effectiveness, while being safe for sensitive skin and having a minimal environmental impact.
9.8

Exceptional

Our Rating

8.7
For Gentle skin

8.4
dispense easily

8.2
Freshness
3

ACTIVE
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads
Main highlights

Effective Stain and Odor Removal
Bio enzymatic formula targets and eliminates tough stains and odors.

Perfect for Activewear and Pet Accidents
Ideal for removing sweat, grease, and pet-related odors.

Highly Recommended for Odor Elimination
Customers praise its ability to remove persistent smells.
Key specs
- Usage:Laundry
- Formulation:Enzyme Powder
- Surface Compatibility:All Fabrics
- Stain Remover:Heavy Duty
- Special Features:Plant-based Formula
9.7

Exceptional

Our Rating
4

ACTIVE
Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads
Main highlights

Powerful Odor and Stain Elimination
ACTIVE Pet Detergent's enzymes tackle pet stains and odors, ensuring fresh results.

Versatile for Pet and Human Laundry
Ideal for pet beds, clothing, and even personal laundry.

Highly Praised Odor Removal
Customers love its ability to remove tough pet odors.
Key specs
- Cleaning Power:Natural cleaning power
- Load Capacity:64 loads
- Formulation:Bio based enzyme cleaner
- Stain Removal:Targets pesky stains
- Eco-Friendly:Natural & free of chemicals
9.6

Exceptional

Our Rating
5

Nature's Miracle
Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

15% Off
Main highlights

Powerful Stain and Odor Removal
Bio-enzymatic formula tackles tough pet stains and odors.

Versatile Laundry Additive
Ideal for clothing, pet beds, and washable fabrics.

Customer Praised Effectiveness
Highly recommended for eliminating odors and stains.
Key specs
- Usage:Clothing, pet beds
- Formulation:Bio-enzymatic
- Surface Compatibility:Not for specialty fabrics
- Stain Remover:Laundry Bio-Enzymatic Formula
- Special Features:OdorCapture 360 Technology
9.5

Excellent

Our Rating

9.9
Vacuum strength

9.5
Simple to use

9.3
Aroma
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6

OxiClean
OxiClean Odor Blasters Versatile Odor and Stain Remover Powder, 5 lb

15% Off
Main highlights

Powerful Stain and Odor Removal
OxiClean Odor Blasters effectively removes tough stains and odors, ensuring clothes are clean and fresh.

Ideal for Laundry and Household Cleaning
Perfect for tackling laundry stains and odors, and versatile enough for kitchen and bathroom cleaning.

Highly Praised for Odor Elimination
Customers frequently praise its ability to eliminate stubborn odors, especially from pet bedding and work clothes.
Key specs
- Usage:Laundry stain remover
- Formulation:Oxygen-based, water-activated
- Surface Compatibility:Machine-washable fabrics
- Stain Remover:OxiClean Odor Blasters
- Special Features:Chlorine-free, color-safe
9.3

Excellent

Our Rating

9.3
Simple to use

9.3
Aroma

9.1
Flexibility
7

Dirty Labs
Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High Efficiency & Standard Machine Washer | Nontoxic, Biodegradable | Stain & Odor Removal Enzyme Booster
Main highlights

Nontoxic Biodegradable Formula
The Dirty Labs Laundry Booster uses a hypoallergenic, nontoxic, and biodegradable formula, free from harsh chemicals, ensuring safety for sensitive skin and the environment.

Ideal for Tough Stain Removal
Perfect for removing biological stains and odors like sweat, body grime, and pet urine, making it ideal for households with kids and pets.

Praised for Odor Elimination
Customers consistently praise its effectiveness in eliminating stubborn odors, especially pet-related, without leaving any residue or overpowering fragrance.
Key specs
- Usage:Laundry booster
- Formulation:Biodegradable formula
- Surface Compatibility:Traditional and HE washers
- Stain Remover:Bioenzyme for biological stains
- Special Features:Hypoallergenic, cruelty-free, vegan
9.2

Excellent

Our Rating

9.9
For Gentle skin

9.5
Aroma

9.5
deep clean
8

ACTIVE
Active Wear Laundry Detergent & Soak - Formulated for Sweat and Workout Clothes - Natural Performance Concentrate Enzyme Booster Deodorizer - Powder Wash for Activewear Gym Apparel (90 Loads)

36% Off
Main highlights

Plant-Based Enzyme Formula
Scientifically formulated with natural enzymes to eliminate odors from sweat and extend clothes lifespan.

Ideal for Activewear
Specialized detergent for workout clothes, including shirts, shorts, and yoga pants.

Odor Elimination Success
Highly praised for removing odors without leaving a perfume scent.
Key specs
- Cleaning Power:Plant-based enzymes
- Load Capacity:90 loads
- Formulation:Powdered detergent
- Stain Removal:Removes sweat smells
- Eco-Friendly:Plant-based, phosphate-free
9.1

Excellent

Our Rating

9.9
For exercise

9.3
Freshness

9.1
Aroma
9

Lysol
Lysol Tough Odor Eliminator Laundry Sanitizer Additive, Sanitizing Liquid for Gym Clothes and Activewear, 0% Bleach, Eliminates Odor Causing Bacteria, 90oz

11% Off
Main highlights

Eliminates Bacteria and Viruses
Removes 99.9% of bacteria and viruses, including SARS-COV-2.

Ideal for Activewear
Perfect for sanitizing gym clothes, sportswear, and uniforms.

Highly Praised Odor Elimination
Customers love its ability to remove persistent odors.
Key specs
- Usage:Sanitize laundry
- Form:Liquid
- Packaging:4.6 x 7.5 x 11.3 inches
- Safety:Bleach and Phosphate free
- Compatibility:Standard & HE machines
9.0

Excellent

Our Rating

9.9
Odor elimination

9.3
Simple to use

8.0
Packaging materials
10

Lazy Coconuts

Lazy Coconuts Complete 5 Enzyme Laundry Detergent Strips - Unscented, 48 Loads - Sulfate Free Laundry Detergent With Solid And Liquid Enzymes - Fights Natural Stains and Odor
8.9

Very Good

Our Rating

10 Best enzyme laundry detergents of 2025

1

Rockin' Green Laundry Detergent, Plant based, All Natural Laundry Detergent Powder, Vegan and Biodegradable Odor Fighter, Safe for Sensitive Skin (Active Wear 90 Loads - Unscented)

9.5

9.5

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) | Hyper-Concentrated | High Efficiency & Standard Machine Washing | Nontoxic, Biodegradable | Stain & Odor Removal

8.7

8.4

8.2

3

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

4

Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads

5

Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

9.9

9.5

9.3

6

OxiClean Odor Blasters Versatile Odor and Stain Remover Powder, 5 lb

9.3

9.3

9.1

7

Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High Efficiency & Standard Machine Washer | Nontoxic, Biodegradable | Stain & Odor Removal Enzyme Booster

9.9

9.5

9.5

8

Active Wear Laundry Detergent & Soak - Formulated for Sweat and Workout Clothes - Natural Performance Concentrate Enzyme Booster Deodorizer - Powder Wash for Activewear Gym Apparel (90 Loads)

9.9

9.3

9.1

9

Lysol Tough Odor Eliminator Laundry Sanitizer Additive, Sanitizing Liquid for Gym Clothes and Activewear, 0% Bleach, Eliminates Odor Causing Bacteria, 90oz

9.9

9.3

8.0

10

Lazy Coconuts Complete 5 Enzyme Laundry Detergent Strips - Unscented, 48 Loads - Sulfate Free Laundry Detergent With Solid And Liquid Enzymes - Fights Natural Stains and Odor

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