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10 Best enzyme drain cleaners of 2026

Save up to 20% off
  • Best Choice

    1

    Garbage Disposal Cleaner Deodorizer Tablets - 24 Pack, New Powerful XL Foaming Tablet - Fresh Citrus Foam Sink Garburator Disposer Freshener, Natural Kitchen Drain Cleaning Care - 1 Year Supply
    ACTIVE
    9.7
    Exceptional

    Garbage Disposal Cleaner Deodorizer Tablets - 24 Pack, New Powerful XL Foaming Tablet - Fresh Citrus Foam Sink Garburator Disposer Freshener, Natural Kitchen Drain Cleaning Care - 1 Year Supply

    15% Off Limited Time Deal
    • mildew resistant:BPA Free, Bleach Free, Chlorine Free
    • product dimensions:8.6 x 7.6 x 0.59 inches
    • specific instructions for use:Garbage Disposal Cleaner and Deodorizer
    • item weight:15.5 ounces
    • item model number:active-disposal-v2-24
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  • Value for Money

    2

    Bioda Professional Strength Enzyme Drain Cleaner, Septic Safe Drain Odor Eliminator, Smell Eliminator, 1 Gallon
    Bioda
    9.5
    Excellent

    Bioda Professional Strength Enzyme Drain Cleaner, Septic Safe Drain Odor Eliminator, Smell Eliminator, 1 Gallon

    • package dimensions:12.05 x 5.94 x 5.83 inches; 9.15 Pounds
    • asin:B07JQ3NG3P
    • date first available:December 21, 2018
    • item model number:BEB-00013
    • best sellers rank:#5 in Commercial Drain Openers

  • 3

    Septic Tank System Treatment Pods - 12 Dissolving Packets | Enzyme-Producing Live Bacteria Solution | 1 Year Supply Professional Eco-Friendly Maintenance | Prevent Clogs, Odor & Backups | Made in USA
    ACTIVE
    9.4
    Excellent

    Septic Tank System Treatment Pods - 12 Dissolving Packets | Enzyme-Producing Live Bacteria Solution | 1 Year Supply Professional Eco-Friendly Maintenance | Prevent Clogs, Odor & Backups | Made in USA

    10% Off Limited Time Deal
    • package dimensions:9.41 x 6.65 x 1.97 inches; 11.68 ounces
    • asin:B0C24VY5PJ
    • date first available:August 14, 2023
    • department:unisex-adult
    • item model number:active-septic-12

  • 4

    Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.
    Bio-Clean
    9.1
    Excellent

    Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! Removes fats Oil and Grease, Completely Cleans Your System.

  • 5

    Drano Max Build Up Remover Drain Cleaner, Enzymes & Probiotics Prevents Clogs & Remove Odor-Causing Buildup, Safe for Septic, Toilets & Pipes in Bathroom Drains & Kitchen Sinks, Commercial Line, 60 oz
    Drano
    9.0
    Excellent

    Drano Max Build Up Remover Drain Cleaner, Enzymes & Probiotics Prevents Clogs & Remove Odor-Causing Buildup, Safe for Septic, Toilets & Pipes in Bathroom Drains & Kitchen Sinks, Commercial Line, 60 oz

    • package dimensions:9.66 x 5.75 x 3.82 inches 4 Pounds
    • asin:B0BGQSD3PJ
    • date first available:September 28, 2022
    • item model number:333671
    • manufacturer:SC Johnson
  • See Today’s Deals & Prices

  • 6

    Drano Balance Drain Clog Remover and Cleaner, Non-Corrosive Formula, Safe on All Pipes and Septic Tanks, Formulated Using Only Essential Ingredients, 32 Fl Oz
    Drano
    8.9
    Very Good

    Drano Balance Drain Clog Remover and Cleaner, Non-Corrosive Formula, Safe on All Pipes and Septic Tanks, Formulated Using Only Essential Ingredients, 32 Fl Oz

    11% Off
    • package dimensions:N/A
    • asin:B0B8LWTHB3
    • date first available:August 3, 2022
    • item model number:351390
    • manufacturer:SC Johnson

  • 7

    Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Pet Stain and Odor Remover, Drain Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce
    Zeiff
    8.8
    Very Good

    Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Pet Stain and Odor Remover, Drain Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce

    • product dimensions:3.35 x 3.35 x 10 inches
    • import:Made in US
    • specific instructions for use:Multi surface cleaner
    • item weight:2 pounds
    • item model number:ZC25018

  • 8

    Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
    Bioda
    8.7
    Very Good

    Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

  • 9

    Zep Drain Defense Pipe Build-Up Remover - 64 Ounces - ZLDC648 - Professional Strength Liquid Pipe Build Up Remover,GREEN
    Zep
    8.6
    Very Good

    Zep Drain Defense Pipe Build-Up Remover - 64 Ounces - ZLDC648 - Professional Strength Liquid Pipe Build Up Remover,GREEN

    • package dimensions:N/A
    • asin:B001AZQR9C
    • date first available:N/A
    • item model number:ZLDC648
    • manufacturer:ZEP COMMERCIAL PRODUCTS

  • 10

    Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon
    Green Gobbler
    8.5
    Good

    Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon

    20% Off

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