9 Best enzyme cleaners of 2025

Save up to 27% off

Editor's Choice

1

Clicked 867 times in the last month

ANGRY ORANGE
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies
Main highlights

Dual Action Enzyme Cleaner
Combines stain removal and odor elimination for pet messes.

Versatile Multi-Surface Use
Ideal for carpets, hardwood, fabrics, and more.

Citrus Scented Success
Customers praise the effective odor removal and pleasant scent.
9.9

Exceptional

Our Rating

9.3
Simple to use

8.9
Aroma

8.7
Odor elimination
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Biokleen
Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic
Main highlights

Eco-Friendly Formula
Bac-Out uses a plant-based, biodegradable formula without harsh chemicals.

Versatile Cleaning Use
Ideal for pet accidents, laundry, carpets, and more.

Effective Odor Removal
Customers praise its ability to eliminate odors effectively.
9.8

Exceptional

Our Rating

9.7
Simple to use

9.5
Aroma

9.5
Odor elimination
3

Black Diamond Stoneworks

Commercial Multi-Purpose Enzyme Cleaner & Odor Eliminator | Pet & Human Urine, Stains & Odors | Carpet, Laundry, Bathroom, Drain & Trash Deodorizer | Dog, Cat, Organic Waste Remover (1 Gallon)
9.7

Exceptional

Our Rating
4

Bioda
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
Main highlights

Powerful Cleaning and Odor Control
This probiotic cleaner offers powerful cleaning and odor elimination for various surfaces, leaving a fresh lemon and sage scent.

Ideal for Pet and Household Use
Perfect for managing pet stains, odors, and maintaining household cleanliness, especially in bathrooms and kitchens.

Highly Effective Odor Elimination
Customers praise its ability to permanently eliminate tough odors, especially from pet-related incidents and organic waste.
Key specs
- volume:1 Gallon
- cleaning method:Probiotic cleaner
- scent:Lemon and sage
- specific instructions:Spray & let probiotics work
- perfume:Lemon and sage
9.6

Exceptional

Our Rating
5

Rocco & Roxie Supply Co.
Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray

27% Off
Main highlights

Certified Safe and Effective
Chlorine-free, color-safe, and CRI-approved for all carpets.

Ideal for Pet Owners
Perfect for removing pet stains and odors from multiple surfaces.

Enzyme-Based Miracle Worker
Customer reviews praise its ability to eliminate odors completely.
Key specs
- Formula:Enzyme Activated
- Use:Stain, Odor Removal
- Stain Type:Urine, Feces, Vomit
- Packaging:Spray
- Safety:Chlorine free, Safe for pets
9.5

Excellent

Our Rating

9.9
worth the money

9.5
Simple to use

8.9
Odor elimination
See Today’s Deals & Prices
6

Zeiff
Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce - Fragrance Free
Main highlights

Pro Grade Cleaning Performance
Zeiff Pro-Grade Formulas deliver effective cleaning, breaking up complex organic proteins, pet stains, hair, grease, fats, and oils without leaving residue.

Versatile Multi-Purpose Use
Ideal for professional and home use, it cleans stains, odors, carpets, floors, kitchen & bathroom surfaces, and prevents clogging in drains and septic tanks.

Highly Effective Odor Elimination
Customers praise its ability to eliminate foul odors from pet accidents, food, garbage, and grease, leaving a long-lasting fresh scent.
9.3

Excellent

Our Rating

9.9
Odor elimination

9.7
Simple to use

9.1
worth the money
7

ACTIVE
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads
Main highlights

Effective Stain and Odor Removal
Bio enzymatic formula targets and eliminates tough stains and odors.

Perfect for Activewear and Pet Accidents
Ideal for removing sweat, grease, and pet-related odors.

Highly Recommended for Odor Elimination
Customers praise its ability to remove persistent smells.
Key specs
- Usage:Laundry
- Volume:32 oz
- Formulation:Enzyme Powder
- Surface Compatibility:All Fabrics
- Stain Remover:Heavy Duty
9.2

Excellent

Our Rating
8

KINZUA ENVIRONMENTAL
KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Effective on Laundry, Carpets & More, Original Scent, 1 Gallon

26% Off
Main highlights

High Enzyme Count for Effective Cleaning
Contains over 200 billion enzymes to liquefy, digest, and eliminate urine and feces.

Versatile Applications for Pet Owners
Ideal for carpets, upholstery, laundry, drains, and toilets; perfect for households with pets.

Customer Praised Stain and Odor Removal
Highly effective in removing pet stains and odors, leaving carpets smelling fresh.
8.9

Very Good

Our Rating

9.1
Simple to use

8.9
Odor elimination

8.4
Aroma
9

Simple Solution
Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz
Main highlights

Powerful Enzymatic Formula
Three times stronger than regular formulas, effectively removes tough pet stains and odors.

Versatile Home Use
Ideal for cleaning dog and cat urine, feces, vomit on carpets, upholstery, and more.

Highly Praised Sprayer
Customers love the improved sprayer for its fine mist and no leakage.
8.8

Very Good

Our Rating

9.7
Odor elimination

9.3
Comfort

9.1
deep clean

9 Best enzyme cleaners of 2025

1

Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

9.3

8.9

8.7

How do we rank?

How do we rank?

Analyzing top stores

2

Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic

9.7

9.5

9.5

3

Commercial Multi-Purpose Enzyme Cleaner & Odor Eliminator | Pet & Human Urine, Stains & Odors | Carpet, Laundry, Bathroom, Drain & Trash Deodorizer | Dog, Cat, Organic Waste Remover (1 Gallon)

4

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

5

Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray

9.9

9.5

8.9

6

Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce - Fragrance Free

9.9

9.7

9.1

7

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

8

KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Effective on Laundry, Carpets & More, Original Scent, 1 Gallon

9.1

8.9

8.4

9

Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz

9.7

9.3

9.1

Sign up and get exclusive special deals