10 Best enzyme cleaner products of 2025

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Editor's Choice

1

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ANGRY ORANGE
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies
Main highlights

Dual Action Enzyme Cleaner
Combines stain removal and odor elimination for pet messes.

Versatile Multi-Surface Use
Ideal for carpets, hardwood, fabrics, and more.

Citrus Scented Success
Customers praise the effective odor removal and pleasant scent.
9.9

Exceptional

Our Rating

9.3
Simple to use

8.9
Aroma

8.7
Odor elimination
How do we rank?

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Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

P & S PROFESSIONAL DETAIL PRODUCTS
P & S Professional Detail Products Terminator Enzyme Spot & Stain Remover – Professional Upholstery & Carpet Cleaner, Eliminates Grease, Dirt, Protein-Based Stains, Fresh Scent - 1 Gallon
Main highlights

Key Features
Powerful enzyme cleaner attacks grease, oil, dirt, and food stains. Deodorizes with a fresh scent. Part of the Renny Doyle Double Black Collection.

Ideal Use Cases
Perfect for pre-treating spots and stains on carpets and upholstery before shampooing. Suitable for both home and professional detailing applications.

Customer Praise
Users highly commend its effectiveness on tough stains, appreciating the fresh scent and the product`s ability to clean and deodorize in a single step.
9.7

Exceptional

Our Rating

9.7
Simple to use

9.3
Simple to take off

9.3
Aroma
3

Bioda
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
Main highlights

Powerful Cleaning and Odor Control
This probiotic cleaner offers powerful cleaning and odor elimination for various surfaces, leaving a fresh lemon and sage scent.

Ideal for Pet and Household Use
Perfect for managing pet stains, odors, and maintaining household cleanliness, especially in bathrooms and kitchens.

Highly Effective Odor Elimination
Customers praise its ability to permanently eliminate tough odors, especially from pet-related incidents and organic waste.
Key specs
- volume:1 Gallon
- cleaning method:Probiotic cleaner
- scent:Lemon and sage
- specific instructions:Spray & let probiotics work
- perfume:Lemon and sage
9.6

Exceptional

Our Rating
4

ACTIVE
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads
Main highlights

Effective Stain and Odor Removal
Bio enzymatic formula targets and eliminates tough stains and odors.

Perfect for Activewear and Pet Accidents
Ideal for removing sweat, grease, and pet-related odors.

Highly Recommended for Odor Elimination
Customers praise its ability to remove persistent smells.
Key specs
- Usage:Laundry
- Volume:32 oz
- Formulation:Enzyme Powder
- Surface Compatibility:All Fabrics
- Stain Remover:Heavy Duty
9.5

Excellent

Our Rating
5

Zeiff
Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce - Fragrance Free
Main highlights

Pro Grade Cleaning Performance
Zeiff Pro-Grade Formulas deliver effective cleaning, breaking up complex organic proteins, pet stains, hair, grease, fats, and oils without leaving residue.

Versatile Multi-Purpose Use
Ideal for professional and home use, it cleans stains, odors, carpets, floors, kitchen & bathroom surfaces, and prevents clogging in drains and septic tanks.

Highly Effective Odor Elimination
Customers praise its ability to eliminate foul odors from pet accidents, food, garbage, and grease, leaving a long-lasting fresh scent.
9.3

Excellent

Our Rating

9.9
Odor elimination

9.7
Simple to use

9.1
worth the money
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6

Aviano

Aviano Cat Enzyme Cleaner – 1 Gallon – Made in USA – Odor Eliminator with Lemon Scent – Pet & Carpet Enzyme Cleaner for Cat Pee, Litter Boxes & Furniture
9.1

Excellent

Our Rating
7

Pestco Products

Enz-O-Matic Enzyme Drain Cleaner - Organic Enzyme-Based Waste Degrader And Odor Neutralizer - 1 Gallon Bottle 128 Fl Oz - Multi-Purpose Enzyme Cleaner - Clean Fresh Scent - Bathroom Accessories
8.8

Very Good

Our Rating
8

ACTIVE
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

20% Off
Main highlights

Complete Odor and Stain Elimination
The enzyme-based formula effectively removes pet stains and odors, leaving a pleasant citrus scent.

Versatile Home Use
Ideal for cleaning carpets, upholstery, hardwood, and various home surfaces affected by pet messes.

Highly Praised Citrus Scent
Customers appreciate the non-overpowering citrus scent that effectively neutralizes odors.
Key specs
- size:32oz
- material:Enzymes and Natural Probiotics
- function:Odor and stain removal
- dimensions:10.2 x 4.65 x 2.83 inches
- color:N/A
8.7

Very Good

Our Rating
9

Green Gobbler
Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon
Main highlights

Effective_Clog_Removal
Utilizes natural enzymes to break down grease, fats, and oils efficiently.

Ideal_Use_for_Slow_Drains
Best used for slow drains and regular maintenance to prevent clogs.

Odor_Control_Praised
Highly praised for eliminating foul odors in drains and pipes.
8.6

Very Good

Our Rating

9.3
Simple to use

8.7
Aroma

8.7
Sheerness
10

Mighty Mint

Mighty Mint Drain Maintainer with Enzymes – Drain Cleaner Controls Bad Smells and Prevents Buildup for Drains, Grease Traps, Septic, 32oz
8.5

Good

Our Rating

10 Best enzyme cleaner products of 2025

1

Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

9.3

8.9

8.7

How do we rank?

How do we rank?

Analyzing top stores

2

P & S Professional Detail Products Terminator Enzyme Spot & Stain Remover – Professional Upholstery & Carpet Cleaner, Eliminates Grease, Dirt, Protein-Based Stains, Fresh Scent - 1 Gallon

9.7

9.3

9.3

3

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

4

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

5

Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce - Fragrance Free

9.9

9.7

9.1

6

Aviano Cat Enzyme Cleaner – 1 Gallon – Made in USA – Odor Eliminator with Lemon Scent – Pet & Carpet Enzyme Cleaner for Cat Pee, Litter Boxes & Furniture

7

Enz-O-Matic Enzyme Drain Cleaner - Organic Enzyme-Based Waste Degrader And Odor Neutralizer - 1 Gallon Bottle 128 Fl Oz - Multi-Purpose Enzyme Cleaner - Clean Fresh Scent - Bathroom Accessories

8

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

9

Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon

9.3

8.7

8.7

10

Mighty Mint Drain Maintainer with Enzymes – Drain Cleaner Controls Bad Smells and Prevents Buildup for Drains, Grease Traps, Septic, 32oz

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