10 Best enzyme cleaners of 2025

Save up to 18% off

Best Choice

1

No Scent Pet Odor Management

No Scent – Carpet, Bedding & Upholstery Cleaner Spray – Enzyme-Based Odor Eliminator for Urine, Stains & Everyday Messes – Pet-Friendly Eco-Conscious Cleaning Solution – 32oz
9.8

Exceptional

Our Rating
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

AmazonCommercial
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
Main highlights

Powerful Enzymatic Cleaning
Breaks down complex organic proteins, pet stains, and odors on various surfaces.

Ideal for Pet Owners
Perfect for homes with pets, tackling messes on carpets, furniture, and more.

Highly Praised Odor Elimination
Customers love its ability to eliminate odors, not just mask them.
Key specs
- Usage:Multi-purpose cleaning
- Form:Liquid
- Volume:1 gallon
- Perfume:Fresh mint scent
- Special Features:Enzymatic formula
9.7

Exceptional

Our Rating

9.3
Simple to use

9.1
worth the money

8.9
Odor elimination
3

Bioda
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
Main highlights

Powerful Cleaning and Odor Control
This probiotic cleaner offers powerful cleaning and odor elimination for various surfaces, leaving a fresh lemon and sage scent.

Ideal for Pet and Household Use
Perfect for managing pet stains, odors, and maintaining household cleanliness, especially in bathrooms and kitchens.

Highly Effective Odor Elimination
Customers praise its ability to permanently eliminate tough odors, especially from pet-related incidents and organic waste.
9.6

Exceptional

Our Rating
4

Rocco & Roxie Supply Co.
Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz
Main highlights

Certified Safe and Effective
Chlorine-free, color-safe, and CRI-approved for all carpets.

Ideal for Pet Owners
Perfect for removing pet stains and odors from multiple surfaces.

Enzyme-Based Miracle Worker
Customer reviews praise its ability to eliminate odors completely.
Key specs
- Formula:Enzyme Activated
- Use:Stain, Odor Removal
- Stain Type:Urine, Feces, Vomit
- Packaging:Spray
- Safety:Chlorine free, Safe for pets
9.5

Excellent

Our Rating

9.9
worth the money

9.5
Simple to use

8.9
Odor elimination
5

Resolve
Resolve Pet Expert Stain and Odor Remover, Carpet Cleaner, Pet Stain and Odor Remover, Carpet & Upholstery Cleaner - Removes Stains and Odors, 22 oz (pack of 1)
Main highlights

Key Features
Exceptional stain removal on first use, prevents resoiling, safe for pets and kids.

Ideal Use Cases
Perfect for tackling pet urine, feces, vomit, and everyday stains like red wine, grape juice, and grease.

Customer Praise
Most reviews highlight its effectiveness on tough stains and appreciate the safety aspect for pets and children.
9.3

Excellent

Our Rating

9.5
Simple to use

9.3
worth the money
See Today’s Deals & Prices
6

Nature's Miracle
Nature’s Miracle Stain and Odor Remover Dog, 32 Ounces, Everyday Mess Enzymatic Odor Control Formula

17% Off
Main highlights

Immediate Stain Removal
Begins to break down and remove stains on contact.

Ideal for Pet Accidents
Perfect for tackling dog messes and pet accidents at home.

Praised Fresh Scent
Customers love its fresh citrus scent and stain removal.
9.1

Excellent

Our Rating

9.7
Stain resistance

9.3
Simple to use

9.1
Odor elimination
7

Nature's Miracle
Nature’s Miracle Urine Destroyer Plus Cat, 32 Ounces, Enzymatic Formula, Ready-to-Use
Main highlights

Powerful Stain and Odor Removal
Enzymatic formula breaks down severe cat urine stains and odors.

Ideal for Persistent Pet Messes
Perfect for cleaning carpets, furniture, and litter box areas.

Highly Effective Odor Control
Praised for eliminating smells, preventing repeat pet marking.
Key specs
- Formula:Enzymatic
- Use:Cat urine messes
- Stain Type:Bio-based mess
- Packaging:2.29 Pounds
- Safety:Safe for pets
8.9

Very Good

Our Rating

9.7
Freshness

9.3
Simple to use

8.4
worth the money
8

Zeiff
Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Pet Stain and Odor Remover, Drain Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce
Main highlights

Key Features and Benefits
Powerful, proprietary enzyme cleaner; breaks down complex stains and odors; safe, non-corrosive, and eco-friendly; ideal for professional and home use.

Ideal Use Cases
Perfect for cleaning pet stains, unclogging drains, removing odors, and general cleaning of floors, carpets, and kitchen/bathroom surfaces.

Customer Reviews Highlight
Most praised for its effectiveness in eliminating tough stains and odors, leaving areas spotlessly clean and freshly scented.
8.8

Very Good

Our Rating

9.7
Simple to use

9.1
worth the money

9.1
Aroma
9

ACTIVE
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads
Main highlights

Effective Stain and Odor Removal
Bio enzymatic formula targets and eliminates tough stains and odors.

Perfect for Activewear and Pet Accidents
Ideal for removing sweat, grease, and pet-related odors.

Highly Recommended for Odor Elimination
Customers praise its ability to remove persistent smells.
Key specs
- Usage:Laundry
- Volume:32 oz
- Formulation:Enzyme Powder
- Surface Compatibility:All Fabrics
- Stain Remover:Heavy Duty
8.7

Very Good

Our Rating
10

Nature's Miracle
Nature's Miracle Dog Stain and Odor Remover, Everyday Mess Enzymatic Formula, 24 fl oz

18% Off
Main highlights

Key Features
Immediate stain removal with light citrus scent, enzymatic formula works on bio-based messes, trusted by Nature`s Miracle brand.

Ideal Use Cases
Perfect for homes with pets, effectively removes stains and odors from accidents on carpets, furniture, and floors.

Customer Reviews
Most praised for its effectiveness in eliminating pet odors and stains, leaving homes smelling fresh and clean.
8.6

Very Good

Our Rating

9.5
Simple to use

8.9
Odor elimination

8.7
deep clean

10 Best enzyme cleaners of 2025

1

No Scent – Carpet, Bedding & Upholstery Cleaner Spray – Enzyme-Based Odor Eliminator for Urine, Stains & Everyday Messes – Pet-Friendly Eco-Conscious Cleaning Solution – 32oz

How do we rank?

How do we rank?

Analyzing top stores

2

AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack

9.3

9.1

8.9

3

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

4

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz

9.9

9.5

8.9

5

Resolve Pet Expert Stain and Odor Remover, Carpet Cleaner, Pet Stain and Odor Remover, Carpet & Upholstery Cleaner - Removes Stains and Odors, 22 oz (pack of 1)

9.5

9.3

6

Nature’s Miracle Stain and Odor Remover Dog, 32 Ounces, Everyday Mess Enzymatic Odor Control Formula

9.7

9.3

9.1

7

Nature’s Miracle Urine Destroyer Plus Cat, 32 Ounces, Enzymatic Formula, Ready-to-Use

9.7

9.3

8.4

8

Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Pet Stain and Odor Remover, Drain Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce

9.7

9.1

9.1

9

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

10

Nature's Miracle Dog Stain and Odor Remover, Everyday Mess Enzymatic Formula, 24 fl oz

9.5

8.9

8.7

Sign up and get exclusive special deals