Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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10 Best enzymatic cleaners of 2026
Save up to 33% off
Best Choice1
Clicked 349 times
in the last weekRocco & Roxie Supply Co.9.6Exceptional
Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon
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Form Factor:Spray
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Certified Safe:Seal of Approval by the Carpet and Rug Institute (CRI)
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Capacity:1-Gallon
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Cleaner Type:Enzyme Cleaner
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Ingredients:Chlorine free, color safe, no hazardous propellants or residue
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Value for Money2
AmazonCommercial9.5Excellent
AmazonCommercial Multi-Purpose Enzyme Cleaner, Stain & Odor Remover, Pet Stain Remover, 1-Gallon, 1-Pack
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asin:B07XL3C6FR
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product dimensions:6.1 x 6.1 x 11.68 inches; 8.6 Pounds
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date first available:January 6, 2020
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item model number:PBH-342711
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best sellers rank:#4 in Commercial All-Purpose Cleaners
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3
Rocco & Roxie Supply Co.9.4Excellent
Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray Clear, 32 Fl Oz
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4
Biokleen9.1Excellent
Biokleen Bac-Out Enzyme Cleaner and Stain & Odor Remover for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic, Lime Scent, 128 Ounces
33% Off Limited Time Deal-
is discontinued by manufacturer:No
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product dimensions:7 x 12 x 7 inches; 0.01 ounces
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asin:B0061VZQWO
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date first available:April 6, 2011
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item model number:B00034
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5
GELEAN9.0Excellent
Multi-Purpose Probiotic Enzyme Citrus Cleaner, 1/2 Gallon (64 oz.) - Pet Stain and Odor Remover - Concentrated - Professional & Home Strength Drains, Floors, Bathrooms, Toilets Trash Can, Made in USA
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Bioda8.9Very Good
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
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asin:B0CJ51KCH4
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product dimensions:N/A
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date first available:September 15, 2023
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item model number:N/A
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best sellers rank:#3 in Commercial All-Purpose Cleaners
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7
Rocco & Roxie Supply Co.8.8Very Good
Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training
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GELEAN8.7Very Good
Enzymatic Cleaner Multi-Purpose Enzyme Cleaner for Dog Urine and Poop Carpet | Cat Pee Odor eliminator Pet Urine Enzyme Drain Cleaner | Floors, Carpets, Laundry, Bathrooms, Trash Can Deodorizer, 128oz
26% Off
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McKesson8.6Very Good
McKesson Multi-Enzymatic Cleanser for Surgical Instruments & General Healthcare Equipment, 1 Gallon [Pack of 1] Fresh Mint
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is discontinued by manufacturer:No
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product dimensions:6 x 6 x 12 inches 8.63 Pounds
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asin:B002C5ZXJ4
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date first available:June 5, 2009
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item model number:53-28501
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Black Diamond Stoneworks8.5Good
Commercial Multi-Purpose Enzyme Cleaner & Odor Eliminator | Pet & Human Urine, Stains & Odors | Carpet, Laundry, Bathroom, Drain & Trash Deodorizer | Dog, Cat, Organic Waste Remover (1 Gallon)
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Frequently Asked Questions
- What is an enzymatic cleaner?
- How does an enzymatic cleaner work?
- Can enzymatic cleaners be used on any surface?
- Are enzymatic cleaners eco-friendly?
- Can I use an enzymatic cleaner for pet stains?
