10 Best dog immune boosts of 2025

Save up to 14% off

Best Choice

1

VetSmart Formulas
Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract - 30-Day Supply
Main highlights

Key Features and Benefits
Enhances pet health with premium ingredients, supporting joint, coat, and overall wellness. Unique formula backed by veterinary science.

Ideal Use Cases
Perfect for aging pets, those with joint issues, or pets needing a nutritional boost for a shiny coat and improved vitality.

Customer Reviews Highlight
Most praised for significantly improving pets` mobility and energy, with noticeable results in joint health and activity levels.
9.7

Exceptional

Our Rating

8.2
Simple to use

8.2
Aroma

8.2
Comfort
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Value for Money

2

Petsmont
Petsmont Buddy Guard for Lumps and Bumps, Lipoma for Dogs & Cats, Patent Pending Organic 8 Mushroom Powder Blend Natural Dog Probiotic & Immune Support Chaga, Reishi, Lion's Mane, Turkey Tail Mushroom
Main highlights

Reduced Lumps and Bumps
Contains Turkey Tail mushroom known to help with dog lumps and bumps, providing smoother, bump-free skin and peace of mind for dog owners.

Ideal for Senior Dogs
Boosts immune system with Reishi and Shiitake mushrooms, increases energy and vitality, making it perfect for senior dogs with lumps and bumps.

Improved Energy and Playfulness
Customers frequently praise the noticeable increase in their senior dogs' energy levels and playfulness after using the supplement.
Key specs
- Size:N/A
- Formulation:Organic supplement
- Dimensions:3.07 x 2.99 x 2.83 inches
- Health Benefit:Stronger immune system
- Origin:N/A
9.6

Exceptional

Our Rating

9.7
Simple to use

9.7
quality of ingredients

8.9
Efficient Energy Use
3

VETRISCIENCE
VetriScience Immunity Health Easy-Open Capsules, 23 Antioxidants for Cell Advance, Immune Plus Supplement for Medium to Large Breed Dogs, Immune and Allergy Support, 120 Count
Main highlights

23 Powerful Antioxidants
Immunity Health offers 23 antioxidants to boost immune health and protect against free-radical damage in all dog breeds and ages.

Ideal for All Breeds
Perfect for owners seeking immune support for dogs of any size, with specific formulas for small and medium/large breeds.

Easy-to-Use Capsules
Customers praise the convenience of capsules that can be added directly to meals or sprinkled over food.
9.5

Excellent

Our Rating
4

Pet Honesty
Dog Allergy & Itch Relief - Advanced Itch Supplement with Probiotics for Dogs - Immune Support & Skin Relief for Seasonal Allergies - Natural Itchy Skin & Paw Relief - (Salmon, 90 Ct)
Main highlights

Supports Immune and Histamine Response
Combines natural ingredients like colostrum and turmeric for healthy immune and histamine response.

Ideal for Seasonal Allergies
Perfect for dogs with seasonal and occasional allergies, soothing skin-related issues.

Praised for Reducing Itching
Customers appreciate its effectiveness in reducing itching and skin irritation.
9.4

Excellent

Our Rating

9.1
Simple to use

9.1
Comfort

8.9
worth the money
5

NaturVet

NaturVet Mushroom Max Advanced Immune Support Dog Supplement – Helps Strengthen Immunity, Overall Health for Dogs – Includes Shitake Mushrooms, Reishi, Turkey Tail – 60 Ct.
9.3

Excellent

Our Rating

9.1
Simple to use

8.9
worth the money

8.2
Flavor
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6

VETRISCIENCE

VetriScience DMG Immunity Health Easy-Dose Liquid, Vetri DMG Immune Support Supplement for Cats and Dogs, Hypoallergenic, Support Performance, Stamina, Immune Response, 30 ml
9.2

Excellent

Our Rating

9.9
dispense easily

9.1
Aroma

8.9
worth the money
7

Nutramax Laboratories

Nutramax Laboratories Nutramax Imuquin Immune Health Supplement Powder for Dogs, with Beta Glucans, Marine Lipids, Vitamins and Minerals, 30 Packets, Updated Version
9.1

Excellent

Our Rating
8

VETIQ
VetIQ Multivitamin Supplement for Dogs, Supports Active Brain Function, Immune System, and Digestive System, Hickory Smoke Flavored Dog Multivitamin, Made in The USA, 60 Count

14% Off
Main highlights

Comprehensive Health Support
VetIQ Multivitamin aids brain, immune, and digestive systems.

Ideal for Training and Anxiety
Perfect for training and calming anxious dogs.

Highly Praised Flavor and Texture
Dogs love the hickory smoke flavor and soft chew texture.
Key specs
- Formulation:Multivitamin
- Dimensions:1.5 x 6.18 x 7.75 inches
- Health Benefit:Supports brain, immune, digestive
- Ingredients:N/A
- Country of Origin:USA
9.0

Excellent

Our Rating

8.0
Flavor

8.0
Simple to use

8.0
worth the money
9

FSLHCY

Milk Thistle for Dogs, 180 Chewable Tablets Milk Thistle Supplement for Dogs Natural Liver Support for Pets, Kidney Cleanse & Repair, Boosts Immune System Peking Duck Flavor
8.9

Very Good

Our Rating
10

PetLab Co.
PetLab Co. Allergy & Immune Probiotics for Dogs, Support Seasonal Allergies, Gut & Digestive Health - Pork Flavor - 30 Soft Chews - Packaging May Vary
Main highlights

Supports Gut Balance and Immune Response
Advanced formula with probiotics for gut health and immune support.

Ideal for Seasonal Allergy Relief
Perfect for dogs with seasonal allergies to promote comfort.

Reduces Paw Licking and Biting
Most praised for reducing paw licking and biting in dogs.
Key specs
- Probiotics:Specialized probiotic dog chews
- Bowel Health:Gut balance support
- Digestive Support:Advanced Formula
- Prebiotics:Premium-quality prebiotics
- Enzymes:N/A
8.8

Very Good

Our Rating

8.0
Flavor

8.0
Aroma

8.0
worth the money

10 Best dog immune boosts of 2025

1

Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract - 30-Day Supply

8.2

8.2

8.2

How do we rank?

How do we rank?

Analyzing top stores

2

Petsmont Buddy Guard for Lumps and Bumps, Lipoma for Dogs & Cats, Patent Pending Organic 8 Mushroom Powder Blend Natural Dog Probiotic & Immune Support Chaga, Reishi, Lion's Mane, Turkey Tail Mushroom

9.7

9.7

8.9

3

VetriScience Immunity Health Easy-Open Capsules, 23 Antioxidants for Cell Advance, Immune Plus Supplement for Medium to Large Breed Dogs, Immune and Allergy Support, 120 Count

4

Dog Allergy & Itch Relief - Advanced Itch Supplement with Probiotics for Dogs - Immune Support & Skin Relief for Seasonal Allergies - Natural Itchy Skin & Paw Relief - (Salmon, 90 Ct)

9.1

9.1

8.9

5

NaturVet Mushroom Max Advanced Immune Support Dog Supplement – Helps Strengthen Immunity, Overall Health for Dogs – Includes Shitake Mushrooms, Reishi, Turkey Tail – 60 Ct.

9.1

8.9

8.2

6

VetriScience DMG Immunity Health Easy-Dose Liquid, Vetri DMG Immune Support Supplement for Cats and Dogs, Hypoallergenic, Support Performance, Stamina, Immune Response, 30 ml

9.9

9.1

8.9

7

Nutramax Laboratories Nutramax Imuquin Immune Health Supplement Powder for Dogs, with Beta Glucans, Marine Lipids, Vitamins and Minerals, 30 Packets, Updated Version

8

VetIQ Multivitamin Supplement for Dogs, Supports Active Brain Function, Immune System, and Digestive System, Hickory Smoke Flavored Dog Multivitamin, Made in The USA, 60 Count

8.0

8.0

8.0

9

Milk Thistle for Dogs, 180 Chewable Tablets Milk Thistle Supplement for Dogs Natural Liver Support for Pets, Kidney Cleanse & Repair, Boosts Immune System Peking Duck Flavor

10

PetLab Co. Allergy & Immune Probiotics for Dogs, Support Seasonal Allergies, Gut & Digestive Health - Pork Flavor - 30 Soft Chews - Packaging May Vary

8.0

8.0

8.0

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