November 5, 2025

Advertising Disclosure

10 Best dewormer for large dogs of 2025

Save up to 20% off

Best Choice

1

Durvet
Durvet Triple Wormer for Medium and Large Dogs
Main highlights

Comprehensive Worm Control
Controls seven strains of tape, hook, and roundworms with chewable tablets.

Ideal for Large Dog Owners
Perfect for treating medium to large dogs with simple dosage instructions.

Dogs Love the Taste
Customers praise the palatability; dogs take tablets like treats.
9.8

Exceptional

Our Rating

9.3
Simple to use

8.9
worth the money

8.9
Flavor
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

PetArmor
PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Large Dogs & Puppies (Over 25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 6 Flavored Chewables
Main highlights

Treats and Controls 7 Worm Species
PetArmor 7 Way Chewable De-Wormer treats and controls 2 types of tapeworms, 2 types of roundworms, and 3 types of hookworms.

Ideal for Large Dogs and Puppies
This vet-quality dewormer is safe for puppies 12 weeks or older and large dogs weighing 25.1 to 200 lbs.

Convenient Chewable Tablets
Customers appreciate the chewable tablets for their ease of administration, making it simple to give to dogs without resistance.
9.7

Exceptional

Our Rating

9.7
Simple to use

9.3
Flavor

9.3
worth the money
3

PetArmor
PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Large Dogs & Puppies (Over 25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 2 Flavored Chewables
Main highlights

Comprehensive Worm Control
Treats and controls 7 species of worms, including tapeworms, roundworms, and hookworms.

Convenient Chewable Tablets
Ideal for easy administration in large dogs and puppies over 25 lbs.

Vet-Quality Standard
Praised for its reliable effectiveness and noticeable health improvements in dogs.
Key specs
- Target Worms:7 species of worms
- Administration:Oral
- Form:Chewable tablets
- Dosage:Chewable tablets
- Safety:Safe for puppies 12+ weeks
9.6

Exceptional

Our Rating

9.3
Simple to use

8.9
worth the money

8.7
Flavor
4

Elanco
Elanco Chewable Quad Dewormer for Large Dogs, 45 lbs and over, 2 chewable tablets

20% Off
Main highlights

Beef-Flavored Chewable Convenience
Easy-to-give beef-flavored tablets make deworming stress-free.

Comprehensive Deworming Solution
Ideal for treating tapeworms, roundworms, hookworms, and whipworms.

Rapid and Effective Results
Praised for quickly eliminating worms, even stubborn cases.
9.5

Excellent

Our Rating

8.9
Simple to use

8.2
worth the money

8.0
Flavor
5

Dog Dewormer Canine
Dog Dewormer Canine 8in1 Safe Guard Safeguard Dogs Large Puppies Pet Wormer 4gr

13% Off
Main highlights

Comprehensive Worm Treatment
Treats against tapeworms, roundworms, hookworms, and whipworms for comprehensive protection.

Ideal for Multi-Pet Households
Perfect for households with multiple dogs due to ease of use.

Highly Praised Ease of Use
Customers appreciate the pre-measured, easy-to-mix granules.
Key specs
- Target Worms:Tapeworms, Roundworms, Hookworms, Whipworms
- Administration:Mix into food
- Form:Granules
- Dosage:3 consecutive days
- Safety:Safe for puppies, pregnant dogs
9.4

Excellent

Our Rating

9.3
Simple to use

9.1
worth the money

9.1
Flavor
See Today’s Deals & Prices
6

WORM X PLUS
WORM X PLUS 7 Way De-Wormer Chewables for Dogs - Tablets for Medium & Large Dogs (Over 25 lbs) (pyrantel pamoate/praziquantel), 2 Count
Main highlights

Broad Spectrum Deworming
Treats two types of tapeworms, two types of roundworms, and three types of hookworms.

Ideal for Medium and Large Dogs
Perfect for dogs and puppies over 25 pounds.

Highly Praised for Effectiveness
Customers report consistent, reliable worm-free results with no adverse reactions.
Key specs
- Target Worms:Tapeworms, roundworms, hookworms
- Administration:With or without food
- Form:Chewable tablet
- Dosage:One chewable tablet
- Safety:N/A
9.2

Excellent

Our Rating

9.1
Simple to use

8.9
worth the money

8.4
Flavor
7

PetArmor
PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces
Main highlights

Effective Worm Treatment
Removes 4 species of worms, including roundworms and hookworms.

Versatile Usage
Ideal for puppies (2 weeks+) and adult dogs in contaminated areas.

Customer Satisfaction
Praised for effectiveness, especially in roundworm treatment.
Key specs
- Target Worms:Roundworms, Hookworms
- Administration:Oral
- Form:Liquid
- Dosage:1 teaspoon per 10 lbs
- Safety:Safe for puppies 2+ weeks
9.0

Excellent

Our Rating

9.5
worth the money

8.9
Simple to use

8.0
Flavor
8

Elanco
Elanco Tapeworm Dewormer (praziquantel tablets) for Dogs, 5 Count (Pack of 1) Praziquantel Tablets for Dogs and Puppies 4 Weeks and Older
Main highlights

Key Features and Benefits
Elanco Tapeworm Dewormer effectively removes Dipylidium caninum and Taenia pisiformis from dogs.

Ideal Use Cases
Best for dogs and puppies over 4 weeks old needing tapeworm removal.

Praised Feature
Customers appreciate its effectiveness in eliminating tapeworms quickly.
Key specs
- Target Worms:Tapeworms
- Administration:Crumble with food or oral
- Form:Tablets
- Dosage:5-count bottle
- Safety:For dogs over 4 weeks
8.9

Very Good

Our Rating

9.5
Simple to use

8.9
worth the money

8.4
Flavor
9

SAFE-GUARD
Guard Canine Dewormer for Large Dogs, 4-Gram (Pack of 2)
Main highlights

Comprehensive Worm Treatment
Safe and effective for treating tapeworms, roundworms, hookworms, and whipworms in dogs.

Ideal for Various Dogs
Suitable for puppies over 6 weeks, pregnant females, and heartworm-infected dogs.

Convenient Feeding Method
Easy-to-use granules mix seamlessly into food for hassle-free administration.
Key specs
- Target Worms:Tapeworms, roundworms, hookworms, whipworms
- Administration:Mix into food
- Form:Granules
- Dosage:3 consecutive days
- Safety:Safe for puppies, pregnant dogs
8.8

Very Good

Our Rating

9.9
Simple to use

9.5
Flavor

8.7
worth the money
10

Panacur
Panacur C Canine Dewormer (Fenbendazole), 4 Gram, 3 Count (Pack of 1), Red
Main highlights

Effective Deworming Solution
Panacur C Canine Dewormer provides a cost-effective solution for treating common canine intestinal worms, including roundworms, hookworms, and whipworms.

Versatile Usage
Ideal for regular deworming routines or when symptoms suggest worm infestations in dogs six weeks and older, including pregnant dogs.

Cost-Effective Alternative
Praised for its affordability compared to veterinary treatments, allowing pet owners to manage worm issues economically.
8.5

Good

Our Rating

9.9
Precision

9.5
Simple to use

9.1
worth the money

10 Best dewormer for large dogs of 2025

1

Durvet Triple Wormer for Medium and Large Dogs

9.3

8.9

8.9

How do we rank?

How do we rank?

Analyzing top stores

2

PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Large Dogs & Puppies (Over 25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 6 Flavored Chewables

9.7

9.3

9.3

3

PetArmor 7 Way De-Wormer for Dogs, Oral Treatment for Tapeworm, Roundworm & Hookworm in Large Dogs & Puppies (Over 25 lbs), Worm Remover (Praziquantel & Pyrantel Pamoate), 2 Flavored Chewables

9.3

8.9

8.7

4

Elanco Chewable Quad Dewormer for Large Dogs, 45 lbs and over, 2 chewable tablets

8.9

8.2

8.0

5

Dog Dewormer Canine 8in1 Safe Guard Safeguard Dogs Large Puppies Pet Wormer 4gr

9.3

9.1

9.1

6

WORM X PLUS 7 Way De-Wormer Chewables for Dogs - Tablets for Medium & Large Dogs (Over 25 lbs) (pyrantel pamoate/praziquantel), 2 Count

9.1

8.9

8.4

7

PetArmor Sure Shot Liquid De-Wormer for Dogs and Puppies, Liquid De-Wormer Treats Roundworms & Hookworms in Dogs and Puppies 2 Weeks and Older, For Dogs Under 120 lbs, 2 ounces

9.5

8.9

8.0

8

Elanco Tapeworm Dewormer (praziquantel tablets) for Dogs, 5 Count (Pack of 1) Praziquantel Tablets for Dogs and Puppies 4 Weeks and Older

9.5

8.9

8.4

9

Guard Canine Dewormer for Large Dogs, 4-Gram (Pack of 2)

9.9

9.5

8.7

10

Panacur C Canine Dewormer (Fenbendazole), 4 Gram, 3 Count (Pack of 1), Red

9.9

9.5

9.1

Sign up and get exclusive special deals