July 24, 2025

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10 Best cat urine remover with enzymes of 2025

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Editor's Choice

1

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ANGRY ORANGE
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

29% Off
Main highlights

Dual Action Enzyme Cleaner
Combines stain removal and odor elimination for pet messes.

Versatile Multi-Surface Use
Ideal for carpets, hardwood, fabrics, and more.

Citrus Scented Success
Customers praise the effective odor removal and pleasant scent.
9.8

Exceptional

Our Rating

9.3
Simple to use

8.9
Aroma

8.7
Odor elimination
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Based on millions of stores and reviews

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Value for Money

2

Eco Strong
Cat Stain And Odor Remover| Enzyme Urine Odor Neutralizer - Stain Remover for Carpet, Litter Boxes, Bedding, and Laundry [Citrus Scent Gallon Value Size]
Main highlights

Eliminates Odors and Stains
This bio-enzymatic spray breaks down and consumes residue, effectively eliminating cat urine odors and stains without masking them.

Ideal for Multi-Surface Cleaning
Safe for carpets, floors, fabrics, bedding, and more. Effective on organic stains and odors from both pets and humans.

Highly Effective Odor Removal
Customers praise the product for completely removing cat urine odors and stains, even from challenging surfaces like carpets and bedding.
9.6

Exceptional

Our Rating

9.3
Stain resistance

9.1
deep clean

8.9
Odor elimination
- Amazon
3

SIMPLE GREEN
Simple Green Cat Stain & Odor Remover - Enzyme Cleaner for Cat Urine, Feces, Blood, Vomit (32 oz Sprayer & 1 gallon Refill)
Main highlights

Key Features
Eliminates tough stains and odors with natural enzymes, safe for pets, works on various surfaces including upholstery and wood.

Ideal Use Cases
Perfect for cleaning urine, feces, vomit, and more from carpets, pet bedding, and even auto upholstery, ensuring a clean, fresh environment.

Customer Praise
Most reviews highlight its effectiveness on even set-in stains and odors, making it a go-to for pet owners for a fresh, clean home.
9.5

Excellent

Our Rating

9.3
Simple to use

8.4
worth the money

8.4
Aroma
- Amazon
4

Rocco & Roxie Supply Co.
Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray

20% Off
Main highlights

Certified Safe and Effective
Chlorine-free, color-safe, and CRI-approved for all carpets.

Ideal for Pet Owners
Perfect for removing pet stains and odors from multiple surfaces.

Enzyme-Based Miracle Worker
Customer reviews praise its ability to eliminate odors completely.
Key specs
- Formula:Enzyme Activated
- Use:Stain, Odor Removal
- Stain Type:Urine, Feces, Vomit
- Packaging:Spray
- Safety:Chlorine free, Safe for pets
9.4

Excellent

Our Rating

9.9
worth the money

9.5
Simple to use

8.9
Odor elimination
- Amazon
5

Nature's Miracle
Nature's Miracle Stain and Odor Remover Cat, Odor Control Formula, Pour
Main highlights

Key Features
Efficiently tackles cat urine, feces, vomit, and drool stains and odors with a refreshing citrus scent, safe for multiple surfaces and pet-friendly.

Ideal Use Cases
Perfect for households with pets, excels on carpets, hard floors, furniture, and fabrics, ensuring a clean, fresh home environment.

Customer Praise
Highly appreciated for its effectiveness in removing tough stains and odors, with many users commending the pleasant citrus aroma.
Key specs
- Formula:Stain and odor remover
- Use:Cat urine, feces, vomit
- Stain Type:Organic stains
- Packaging:8.4 Pounds
- Safety:Safe for pets and home
9.3

Excellent

Our Rating

8.9
Simple to use

8.7
worth the money

8.7
Odor elimination
- Amazon
- PetSmart
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6

Simple Solution
Simple Solution Extreme Cat Stain Eliminator for Strong Odor, Pet Odor Eliminator for Home, Stain Remover for Cats, Floor Cleaner, Urine Destroyer, Carpet Cleaner Spray, 32oz
Main highlights

Powerful_Enzymatic_Cleaning
Formulated with 3X Pro-Bacteria cleaning power to eliminate tough cat odors and stains.

Versatile_Use_Cases
Ideal for carpets, bedding, fabric, and most water-safe surfaces.

Highly_Effective_Odor_Removal
Praised by users for completely eliminating cat urine smell.
9.2

Excellent

Our Rating

8.9
Simple to use

8.0
Aroma

8.0
worth the money
- Amazon
7

ACTIVE
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

20% Off
Main highlights

Complete Odor and Stain Elimination
The enzyme-based formula effectively removes pet stains and odors, leaving a pleasant citrus scent.

Versatile Home Use
Ideal for cleaning carpets, upholstery, hardwood, and various home surfaces affected by pet messes.

Highly Praised Citrus Scent
Customers appreciate the non-overpowering citrus scent that effectively neutralizes odors.
9.1

Excellent

Our Rating
- Amazon
8

Simple Solution
Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz
Main highlights

Powerful Enzymatic Formula
Three times stronger than regular formulas, effectively removes tough pet stains and odors.

Versatile Home Use
Ideal for cleaning dog and cat urine, feces, vomit on carpets, upholstery, and more.

Highly Praised Sprayer
Customers love the improved sprayer for its fine mist and no leakage.
9.0

Excellent

Our Rating

9.7
Odor elimination

9.3
Comfort

9.1
deep clean
- Amazon
9

ACTIVE
Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads

24% Off
Main highlights

Powerful Odor and Stain Elimination
ACTIVE Pet Detergent's enzymes tackle pet stains and odors, ensuring fresh results.

Versatile for Pet and Human Laundry
Ideal for pet beds, clothing, and even personal laundry.

Highly Praised Odor Removal
Customers love its ability to remove tough pet odors.
Key specs
- Cleaning Power:Natural cleaning power
- Load Capacity:64 loads
- Formulation:Bio based enzyme cleaner
- Hypoallergenic:Gentle for sensitive skin
- Stain Removal:Targets pesky stains
8.9

Very Good

Our Rating
- Amazon
10

KIDS 'N' PETS
KIDS 'N' PETS Instant All-Purpose Stain & Odor Remover Permanently Eliminates Dog Pee, Cat Urine, Other Smells, Spots from Home Carpet, Couch, Furniture, Mattress, Fabric. Non-Toxic, Child Safe - 27oz
Main highlights

Neutralizes Odors and Stains
Patented formula effectively neutralizes and eliminates tough odors and stains, ensuring a deep clean.

Versatile Application
Ideal for use on carpets, furniture, bedding, and any water-safe surfaces.

Highly Effective Odor Removal
Praised for exceptional ability to permanently eliminate urine and other odors.
Key specs
- Usage:Household stains & odors
- Formulation:Patented formula
- Surface Compatibility:Carpet, furniture, mattresses
- Stain Remover:Instant All-purpose
- Special Features:Non-Toxic & Cruelty-Free
8.8

Very Good

Our Rating

9.9
Stain resistance

9.5
Simple to use

9.1
worth the money
- Amazon

10 Best cat urine remover with enzymes of 2025

1

Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

9.3

8.9

8.7

How do we rank?

How do we rank?

Analyzing top stores

2

Cat Stain And Odor Remover| Enzyme Urine Odor Neutralizer - Stain Remover for Carpet, Litter Boxes, Bedding, and Laundry [Citrus Scent Gallon Value Size]

9.3

9.1

8.9

3

Simple Green Cat Stain & Odor Remover - Enzyme Cleaner for Cat Urine, Feces, Blood, Vomit (32 oz Sprayer & 1 gallon Refill)

9.3

8.4

8.4

4

Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray

9.9

9.5

8.9

5

Nature's Miracle Stain and Odor Remover Cat, Odor Control Formula, Pour

8.9

8.7

8.7

6

Simple Solution Extreme Cat Stain Eliminator for Strong Odor, Pet Odor Eliminator for Home, Stain Remover for Cats, Floor Cleaner, Urine Destroyer, Carpet Cleaner Spray, 32oz

8.9

8.0

8.0

7

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

8

Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz

9.7

9.3

9.1

9

Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads

10

KIDS 'N' PETS Instant All-Purpose Stain & Odor Remover Permanently Eliminates Dog Pee, Cat Urine, Other Smells, Spots from Home Carpet, Couch, Furniture, Mattress, Fabric. Non-Toxic, Child Safe - 27oz

9.9

9.5

9.1

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