10 Best blemish spot treatments of 2025

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Best Choice

1

CeraVe
CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz

15% Off
Main highlights

Advanced Exfoliation and Hydration
Combines BHA and AHA to clear acne, smooth skin, and maintain moisture.

Ideal for Sensitive and Acne-Prone Skin
Perfect for those seeking gentle yet effective acne treatment.

Unmatched Performance and Affordability
Praised for its effective results and affordable price point.
9.8

Exceptional

Our Rating

8.9
worth the money

8.9
For Gentle skin

8.7
Aroma
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Value for Money

2

Mario Badescu
Mario Badescu Drying Lotion for All Skin Types| Blemish Spot Treatment with Salicylic Acid and Sulfur | Dries Surface Blemishes | 1 Fl Oz

24% Off
Main highlights

Key Features and Benefits
Fast-acting acne treatment, reduces blemish size overnight, suitable for occasional use.

Ideal Use Cases
Best for emergency acne treatment, spot application for quick results.

Praised Feature
Highly effective in reducing blemish size and duration.
9.7

Exceptional

Our Rating

8.0
For Gentle skin

8.0
Aroma

8.0
Moisturizing
3

Mighty Patch
Mighty Patch™ Original patch from Hero Cosmetics – The #1 Hydrocolloid Acne Pimple Patch for Shrinking Zits and Whiteheads in 1 use; Nighttime Spot Stickers for Face and Skin (36 Count)
Main highlights

Overnight Pimple Treatment
Mighty Patch Original uses hydrocolloid to visibly improve pimples overnight, reducing redness and size.

Best for Night Use
Ideal for overnight use, these patches stay on securely while you sleep.

Customer Praised Adhesion
Customers love the strong adhesion that keeps the patch in place all night.
9.4

Excellent

Our Rating

9.5
Simple to use

9.5
Simple to take off

9.5
Attachment
4

The Ordinary
The Ordinary Salicylic Acid 2% Solution, Acne-Fighting Serum for Blemish-Prone Skin, 1 Fl Oz
Main highlights

Blemish-Reduction Formula
The Ordinary Salicylic Acid 2% Solution targets acne and blemishes effectively.

Ideal for Oily Skin
Best used for oily and blemish-prone skin types.

Customer Praised Clarity
Users frequently commend its ability to clear skin blemishes.
9.1

Excellent

Our Rating
5

Amazon Basics
Amazon Basics Advanced Blemish Spot Treatment with 2% Salicylic Acid Acne Medication, 0.75 Fluid Ounces, 1-Pack
Main highlights

Advanced Acne Treatment
Formulated with 2% Salicylic Acid to effectively treat acne.

Targeted Spot Application
Ideal for applying on specific blemishes one to three times daily.

High Volume Tube
Praised for containing a generous amount of product.
Key specs
- Skin Benefits:Acne treatment
- Formulation:Spot treatment
- Application Frequency:One to three times daily
- Active Ingredient:2% Salicylic Acid
- Skin Type:N/A
8.9

Very Good

Our Rating
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6

AcneFree
AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1
Main highlights

Maximum Strength Benzoyl Peroxide
Contains 10% benzoyl peroxide for effective acne treatment and redness control.

Ideal for Spot Treatment
Best used for treating individual pimples and mild recurring acne.

Convenient Flip-Cap Design
Praised for its easy-to-use flip-cap that prevents loss and simplifies application.
Key specs
- Skin Benefits:Redness Control
- Formulation:Cream
- Application Frequency:N/A
- Active Ingredient:N/A
- Skin Type:N/A
8.7

Very Good

Our Rating

9.7
quality of ingredients

8.4
worth the money

8.0
Sheerness
7

Neutrogena
Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube

30% Off
Main highlights

Effective Acne Treatment with Benzoyl Peroxide
.75-ounce tube with 2.5% benzoyl peroxide fights acne gently.

Ideal for Daily Use on Acne-Prone Skin
Use up to three times daily without over-drying.

Praised for Quick and Visible Results
Customers appreciate its effectiveness and quick results.
Key specs
- Skin Type:All skin types
- Formulation:Cream
- Effects:Fights acne
- Niacinamide:N/A
- Hyaluronic Acid:N/A
8.5

Good

Our Rating
8

e.l.f.
e.l.f. SKIN Blemish Breakthrough Blemish Fighting Spot Gel, Roll-on Blemish Spot Gel For Targeting & Treating Blemishes, Infused With Salicylic Acid
Main highlights

Acne Fighting Formula
Infused with Salicylic Acid, treats and prevents blemishes.

Ideal for Oily Skin
Perfect for acne-prone, oily skin types needing quick relief.

Cooling Sensation
Praised for its soothing, cool feeling and redness reduction.
Key specs
- Function:Acne treatment
- Skin Type:Oily and acne-prone
- Usage:Up to three times daily
- Size:0.63 ounces
- Ingredients:Salicylic Acid, Aloe, Witch Hazel
8.4

Good

Our Rating
9

Neutrogena
Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel, Maximum Strength 10% Benzoyl Peroxide Treatment Medication for Acne Prone Skin, Pimple Cream Reduces Size & Redness in 2 Hours, 1 oz

27% Off
Main highlights

Maximum Strength Benzoyl Peroxide
Contains 10% benzoyl peroxide for rapid acne reduction.

Ideal for Stubborn Acne
Perfect for treating stubborn acne on acne-prone skin.

Quick and Effective Results
Praised for reducing acne size and redness within hours.
8.3

Good

Our Rating

8.7
Aroma

8.4
Fashion

8.2
worth the money
10

Daolyo

Daolyo Pimple Patches for Face, 4 Size 300 Counts Acne Patches, Hydrocolloid Patches for Covering Zits and Blemishes, Spot Stickers with Salicylic Acid, Tea Tree Oil & Calendula Oil
8.2

Good

Our Rating

9.9
Simple to use

9.9
worth the money

9.9
Comfort

10 Best blemish spot treatments of 2025

1

CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz

8.9

8.9

8.7

How do we rank?

How do we rank?

Analyzing top stores

2

Mario Badescu Drying Lotion for All Skin Types| Blemish Spot Treatment with Salicylic Acid and Sulfur | Dries Surface Blemishes | 1 Fl Oz

8.0

8.0

8.0

3

Mighty Patch™ Original patch from Hero Cosmetics – The #1 Hydrocolloid Acne Pimple Patch for Shrinking Zits and Whiteheads in 1 use; Nighttime Spot Stickers for Face and Skin (36 Count)

9.5

9.5

9.5

4

The Ordinary Salicylic Acid 2% Solution, Acne-Fighting Serum for Blemish-Prone Skin, 1 Fl Oz

5

Amazon Basics Advanced Blemish Spot Treatment with 2% Salicylic Acid Acne Medication, 0.75 Fluid Ounces, 1-Pack

6

AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1

9.7

8.4

8.0

7

Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube

8

e.l.f. SKIN Blemish Breakthrough Blemish Fighting Spot Gel, Roll-on Blemish Spot Gel For Targeting & Treating Blemishes, Infused With Salicylic Acid

9

Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel, Maximum Strength 10% Benzoyl Peroxide Treatment Medication for Acne Prone Skin, Pimple Cream Reduces Size & Redness in 2 Hours, 1 oz

8.7

8.4

8.2

10

Daolyo Pimple Patches for Face, 4 Size 300 Counts Acne Patches, Hydrocolloid Patches for Covering Zits and Blemishes, Spot Stickers with Salicylic Acid, Tea Tree Oil & Calendula Oil

9.9

9.9

9.9

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