August 22, 2025

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10 Best hypoallergenic pillow protectors of 2025

Save up to 20% off

Best Choice

1

SureGuard Mattress Protectors
Set of 2 Standard Size SureGuard Pillow Protectors - 100% Waterproof, Bed Bug Proof, Hypoallergenic - Premium Zippered Cotton Terry Covers
Main highlights

Key Features
100% Waterproof, Bed Bug Proof, Hypoallergic, Soft & Noiseless with a 10-year guarantee. Offers total protection and comfort.

Ideal Use
Perfect for those with allergies, pet owners, and anyone looking to protect their pillows from liquids, stains, and bed bugs.

Customer Praise
Most reviews highlight its effectiveness in protection against allergens and comfort, appreciating its noiselessness and quality.
9.9

Exceptional

Our Rating

9.7
Simple to clean

9.5
lasts a long time

9.5
Easy to care
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Value for Money

2

Aller-Ease
Set of 4 Standard/Queen AllerEase Pillow Protectors - Moisture Wicking, Advanced Allergy Protection - Premium Polyester, Zippered Protectors
Main highlights

Key Features
Features tightly woven fabric for allergy protection, breathable material for comfort, and extends pillow life with a durable zippered encasement.

Ideal Use Cases
Perfect for allergy sufferers needing a clean sleep environment, and anyone wanting to keep their pillows fresh and free from dust or mites.

Customer Reviews Highlight
Most praised for being soft, quiet, and effectively blocking allergens, leading to improved sleep quality for allergy sufferers.
Key specs
- size:28L x 20W
- fabric:88 Polyester, 12 Nylon
- zipper:Durable and comfortable
- thread count:240
- breathable:Yes
9.8

Exceptional

Our Rating

9.7
Gentle

9.7
Simple to clean

9.5
Water tight
3

Aller-Ease
Set of 4 Standard/Queen AllerEase Pillow Protectors - Temperature Balancing, Allergist Recommended - Premium Breathable, Zippered Protectors
Main highlights

Advanced Allergy Protection
Tightly woven fabric prevents allergens from collecting in pillows.

Ideal for Allergy Sufferers
Perfect for those needing allergist-recommended pillow protection.

Praised Temperature Balancing
Customers love the temperature regulation for a comfortable sleep.
Key specs
- size:28L x 20W
- fabric:88 Polyester, 12 Nylon
- zipper:Zippered protector
- thread count:240
- breathable:Temperature balancing
9.7

Exceptional

Our Rating

9.9
materials Quality

9.7
Simple to clean

9.5
Gentle
4

Aller-Ease
Set of 2 Standard/Queen AllerEase Pillow Protectors - Moisture Wicking, Advanced Allergy Protection - Premium Polyester, Zippered Protectors
Main highlights

Key Features
Features tightly woven fabric for allergy protection, breathable and heat-resistant material for comfort, and extends pillow life with a durable zippered cover.

Ideal Use Cases
Perfect for individuals with allergies, hot sleepers needing a cool surface, and anyone looking to protect and prolong their pillow`s lifespan.

Customer Reviews Summary
Most praised for its ability to block allergens effectively, maintain a cool sleeping temperature, and the quietness of the fabric during movement.
Key specs
- size:28L x 20W
- fabric:88 Polyester, 12 Nylon
- zipper:Yes
- thread count:240
- breathable:Yes
9.6

Exceptional

Our Rating

9.5
Gentle

9.5
Simple to clean

9.5
Comfort
5

Four Seasons Essentials
Standard Pillow Protectors (Set of 2) – Zippered Waterproof Pillow Covers Hypoallergenic Dust and Allergen Proof Pillowcase Encasement

11% Off
Main highlights

Key Features
100% waterproof with a polyurethane lining, soft and noiseless design, hypoallergenic with a fully zippered enclosure for ultimate protection.

Ideal Use Cases
Perfect for households with pets and children, protecting against spills, stains, and allergens for a cleaner sleep environment.

Customer Reviews Summary
Most praised for its effectiveness in waterproofing and its ability to stay noiseless and comfortable, enhancing sleep quality.
Key specs
- size:21W x 27L
- fabric:Polyester top surface
- zipper:Zipper closure
- thread count:300
- breathable:Stretchable, breathable fabric
9.3

Excellent

Our Rating

9.9
worth the money

9.5
materials Quality

9.5
Simple to clean
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6

Aller-Ease
Set of 2 Standard/Queen AllerEase Pillow Protectors - Temperature Balancing, Allergist Recommended - Premium Breathable, Zippered Protectors
Main highlights

Advanced_Allergy_Protection
AllerEase pillow protectors feature tightly woven fabric to block allergens and household particles, ensuring a healthier sleeping environment.

Ideal_Use_Cases
Perfect for allergy sufferers, households with dust mites, and anyone looking to extend the life of their pillows while maintaining comfort and cleanliness.

Praised_Feature
Customers consistently praise the soft and comfortable material, which effectively protects against allergens and extends pillow life without compromising on comfort.
Key specs
- size:28L x 20W
- fabric:88 Polyester, 12 Nylon
- zipper:Yes
- thread count:240
- breathable:Yes
9.2

Excellent

Our Rating

9.9
materials Quality

9.7
Simple to clean

9.5
Gentle
7

Amazon Basics
Amazon Basics Standard Pillowcase with Zipper, 100% Cotton Hypoallergenic, Pillow Protector, White (27 x 21 Inches), Pillows Not Included
Main highlights

Hypoallergenic and Comfortable Sleep
Crafted from 100% cotton, this pillowcase minimizes allergens for a restful sleep.

Ideal for Allergy Sufferers
Perfect for those seeking a clean, allergen-free sleep environment.

Praised Zipper Enclosure
Customers love the secure zipper that keeps pillows protected.
Key specs
- size:27L x 21W
- color:white
- material:100 Cotton
- special feature:hypoallergenic protection
- closure:zipper closure
9.1

Excellent

Our Rating
8

National Allergy
National Allergy Premium 100% Cotton Zippered Pillow Protector - Queen Size - White - 300 Thread Count - Hypoallergenic Bed Pillowcase with Zipper - Breathable Encasement Cover
Main highlights

Advanced Protection with Zipper System
The pillow protector features an exclusive Zipper System, fully encasing and protecting your pillow with an auto-locking zipper and fabric shield.

Ideal for Allergy Sufferers
Recommended by doctors, this hypoallergenic cover is perfect for those seeking a healthier sleep environment.

Breathable and Quiet Comfort
Customers praise the noiseless, breathable cotton fabric that enhances comfort without compromising protection.
Key specs
- size:31L x 21W
- fabric:100 Cotton
- zipper:Zippered Two-Part System
- thread count:300
- breathable:100 breathable cotton
8.8

Very Good

Our Rating
9

Utopia Bedding
Utopia Bedding Waterproof Pillow Protectors Zippered Queen Size (2 Pack, White), Zippered Pillowcases, Bed Bug Proof Pillow Encasement Covers 20 x 28 Inches

20% Off
Main highlights

PILLOW_ENCASEMENT_PACK_OF_2
Perfectly fits Queen sized pillow, measuring 20 by 28 inches each. Polyester knitted jersey fabric provides comfort, TPU coating makes it waterproof.

Ideal_for_Travel_and_Protection
Great for travel bags, protecting from bed bugs and dust mites, and interior casings for new fluff for sofa pillows.

Praised_Feature
High-quality zip and double hemmed stitching provide protection, and the waterproof feature is highly appreciated for its effectiveness and durability.
Key specs
- size:20 by 28 inches
- fabric:Polyester knitted jersey
- zipper:High-quality zip
- thread count:N/A
- breathable:N/A
8.7

Very Good

Our Rating

9.7
Simple to use

9.3
lasts a long time

9.3
Comfort
10

HOSPITOLOGY PRODUCTS
HOSPITOLOGY PRODUCTS Pillow Encasement- Zippered Bed Bug Dust Mite Proof Hypoallergenic - Sleep Defense System - Standard - Waterproof - Set of 2 - 20" H x 26" W

14% Off
Main highlights

Key Features and Benefits
100% waterproof, extra-soft polyester knit, breathable membrane, machine washable, 5-Year Warranty. Protects against fluids, enhances sleep, cool and comfortable.

Ideal Use Cases
Perfect for individuals prone to sweating, drooling, or allergies. Great for homes with pets, children, or in care settings to protect pillows.

Customer Reviews Summary
Most praised for its effective waterproofing without compromising comfort or breathability, leading to enhanced sleep quality.
8.5

Good

Our Rating

9.5
Water tight

9.5
Simple to clean

9.3
Gentle

10 Best hypoallergenic pillow protectors of 2025

1

Set of 2 Standard Size SureGuard Pillow Protectors - 100% Waterproof, Bed Bug Proof, Hypoallergenic - Premium Zippered Cotton Terry Covers

9.7

9.5

9.5

How do we rank?

How do we rank?

Analyzing top stores

2

Set of 4 Standard/Queen AllerEase Pillow Protectors - Moisture Wicking, Advanced Allergy Protection - Premium Polyester, Zippered Protectors

9.7

9.7

9.5

3

Set of 4 Standard/Queen AllerEase Pillow Protectors - Temperature Balancing, Allergist Recommended - Premium Breathable, Zippered Protectors

9.9

9.7

9.5

4

Set of 2 Standard/Queen AllerEase Pillow Protectors - Moisture Wicking, Advanced Allergy Protection - Premium Polyester, Zippered Protectors

9.5

9.5

9.5

5

Standard Pillow Protectors (Set of 2) – Zippered Waterproof Pillow Covers Hypoallergenic Dust and Allergen Proof Pillowcase Encasement

9.9

9.5

9.5

6

Set of 2 Standard/Queen AllerEase Pillow Protectors - Temperature Balancing, Allergist Recommended - Premium Breathable, Zippered Protectors

9.9

9.7

9.5

7

Amazon Basics Standard Pillowcase with Zipper, 100% Cotton Hypoallergenic, Pillow Protector, White (27 x 21 Inches), Pillows Not Included

8

National Allergy Premium 100% Cotton Zippered Pillow Protector - Queen Size - White - 300 Thread Count - Hypoallergenic Bed Pillowcase with Zipper - Breathable Encasement Cover

9

Utopia Bedding Waterproof Pillow Protectors Zippered Queen Size (2 Pack, White), Zippered Pillowcases, Bed Bug Proof Pillow Encasement Covers 20 x 28 Inches

9.7

9.3

9.3

10

HOSPITOLOGY PRODUCTS Pillow Encasement- Zippered Bed Bug Dust Mite Proof Hypoallergenic - Sleep Defense System - Standard - Waterproof - Set of 2 - 20" H x 26" W

9.5

9.5

9.3

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