June 25, 2025

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10 Best eye drops for severe dry eyes of 2025

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Best Choice

1

Rain

Rain Preservative Free Eye Drops for Severe Dry Eyes – More Natural Eye Drops for Dry Eye Relief – Proprietary Formula Relieves Dry, Itchy Eyes – Take Back Your Eye Comfort
9.9

Exceptional

Our Rating
How do we rank?

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Based on millions of stores and reviews

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Analyzing top stores
Value for Money

2

Optase
OPTASE MGD Advanced Dry Eye Drops - Preservative Free Drops for Dry Eyes and MGD - Lipid-Based Artificial Tears - Demet Technology, Multidose Bottle, Contact Lens Safe - .33 fl oz, 300 Doses
Main highlights

Superior Lubrication and Hydration
OPTASE MGD Advanced Eye Drops offer non-blurry, lipid-based hydration for moderate to severe MGD symptoms relief.

Ideal for Post-Surgery and Dry Eye Relief
Recommended for individuals requiring long-lasting, non-irritating eye moisture, especially post-surgery and for dry eyes.

Highly Recommended by Users
Users praise its ability to keep eyes moist without burning or blurring, offering lasting comfort.
9.8

Exceptional

Our Rating

8.4
Long life

8.2
Moisturizing

8.0
dispense easily
3

BLINK
Blink Eye Drops for Dry Eyes, Triple Care Lubricant Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz

11% Off
Main highlights

Extended Dry Eye Relief
Blink Triple Care drops offer instant, long-lasting relief for moderate to severe dry eye symptoms.

Ideal for Screen Users
Perfect for computer users experiencing dry eye-induced blurry vision.

Customer Praised Hydration
Praised for effective hydration without causing blurry vision or discomfort.
9.6

Exceptional

Our Rating
4

BLINK
Blink GelTears Eye Drops for Dry Eyes, Gel Lubricating Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz

23% Off
Main highlights

Immediate and Long-Lasting Relief
Experience immediate and long-lasting dry eye relief with Blink GelTears' viscous formula, ideal for both day and night use.

Ideal for Post-LASIK Recovery
Perfect for post-LASIK recovery, providing essential lubrication and comfort for sensitive eyes.

Highly Praised Comfort
Customers praise Blink GelTears for its instant comfort and long-lasting relief, outperforming other brands.
9.4

Excellent

Our Rating

9.1
Simple to use

9.1
Comfort

8.4
worth the money
5

iVIZIA
iVIZIA Lubricant Eye Gel for Severe and Nighttime Dry Eye Relief, Preservative-Free, Moisturizing, 30 Sterile Single-Use Vials Packaging May Vary
Main highlights

Thicker Formula for Overnight Use
The gel provides more lubrication and moisture than daytime formulas, ideal for relieving severe dry eye symptoms, especially overnight.

Ideal for Severe Dry Eye or Nighttime Use
iVIZIA Lubricant Eye Gel is perfect for individuals with severe dry eye symptoms or those needing extra moisture during nighttime.

Long-Lasting Hydration
Customers frequently praise the product for its ability to provide lasting relief and hydration, reducing the need for frequent reapplication.
9.2

Excellent

Our Rating

9.7
Moisturizing

8.7
worth the money

8.0
Simple to use
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6

Systane
Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each
Main highlights

Fast Long-Lasting Relief
Provides quick and extended relief for dry eye symptoms.

Ideal for On-the-Go Use
Perfect for soothing irritated eyes anytime, anywhere.

Highly Rated by Users
Praised for relieving dryness and reducing redness efficiently.
9.1

Excellent

Our Rating

9.5
Moisturizing

9.1
Long life

8.9
worth the money
7

TheraTears
TheraTears Extra Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, 0.5 fl oz Bottle, 2 Count(Pack of 1)

35% Off
Main highlights

Extraordinary Hydration
Provides up to 12 hours of hydrating comfort for dry eyes.

Ideal for Laser Corrected Eyes
Perfect for those needing relief post-laser eye surgery.

Silky Texture
Praised for its silky feel and non-irritating application.
9.0

Excellent

Our Rating

9.9
Simple to use

9.1
Moisturizing

9.1
Comfort
8

OCuSOFT
OCuSOFT Retaine MGD Ophthalmic Emulsion - Complete Dry Eye Relief - Soothes Red & Irritated Eyes - 30 Count Preservative-Free Single-Use Containers - 0.01 Fl Oz

24% Off
Main highlights

Moisturizing Lubrication
Retained MGD offers long-lasting relief with preservative-free emulsion.

Ideal for Severe Dry Eyes
Perfect for moderate to severe dry eye conditions.

Highly Praised Effectiveness
Customers love its soothing effect and non-irritating formula.
8.8

Very Good

Our Rating

9.3
Moisturizing

8.9
Long life

8.4
worth the money
9

Rohto
Rohto Dry Aid Lubricant Eye Drops, Fast Relief for Dry Eyes, Long-Lasting Hydration, Dry Eye Symptom Relief, Moisturizing and Soothing Eye Drops for Dry Eyes, Contact Lens-Friendly, 0.34 fl oz
Main highlights

Fast-Acting Non-Blurring Relief
Provides quick relief with Liquidshield technology, mimicking real tears.

Ideal for Digital Eye Strain
Perfect for dryness from electronics, hormonal, or environmental factors.

Praised for Comfort
Users appreciate the cooling sensation and extended relief periods.
8.7

Very Good

Our Rating

9.1
Moisturizing

8.7
worth the money

8.7
Long life
10

NOVEHA
NOVEHA Pet Gel Eye Drops with 0.3% Viscoadaptive Hyaluronan | Eye Solution for Severe Dry Eyes - Long Lasting Hydration, Reduces Nuisance, Swelling & Dryness - Eye Lube for Dogs and Cats (2x10mL)
Main highlights

Immediate Hydration and Comfort
NOVEHA Gel Eye Drops provide instant soothing hydration and lubrication for severely irritated pet eyes.

Ideal for Severe Dry Eye Relief
Perfect for pets suffering from severe dry eye conditions, offering long-lasting relief and comfort.

Ease of Application
Praised for easy application, especially beneficial for pets resistant to treatments.
8.4

Good

Our Rating

9.9
Simple to use

8.0
worth the money

8.0
Comfort

10 Best eye drops for severe dry eyes of 2025

1

Rain Preservative Free Eye Drops for Severe Dry Eyes – More Natural Eye Drops for Dry Eye Relief – Proprietary Formula Relieves Dry, Itchy Eyes – Take Back Your Eye Comfort

How do we rank?

How do we rank?

Analyzing top stores

2

OPTASE MGD Advanced Dry Eye Drops - Preservative Free Drops for Dry Eyes and MGD - Lipid-Based Artificial Tears - Demet Technology, Multidose Bottle, Contact Lens Safe - .33 fl oz, 300 Doses

8.4

8.2

8.0

3

Blink Eye Drops for Dry Eyes, Triple Care Lubricant Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz

4

Blink GelTears Eye Drops for Dry Eyes, Gel Lubricating Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz

9.1

9.1

8.4

5

iVIZIA Lubricant Eye Gel for Severe and Nighttime Dry Eye Relief, Preservative-Free, Moisturizing, 30 Sterile Single-Use Vials Packaging May Vary

9.7

8.7

8.0

6

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

9.5

9.1

8.9

7

TheraTears Extra Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, 0.5 fl oz Bottle, 2 Count(Pack of 1)

9.9

9.1

9.1

8

OCuSOFT Retaine MGD Ophthalmic Emulsion - Complete Dry Eye Relief - Soothes Red & Irritated Eyes - 30 Count Preservative-Free Single-Use Containers - 0.01 Fl Oz

9.3

8.9

8.4

9

Rohto Dry Aid Lubricant Eye Drops, Fast Relief for Dry Eyes, Long-Lasting Hydration, Dry Eye Symptom Relief, Moisturizing and Soothing Eye Drops for Dry Eyes, Contact Lens-Friendly, 0.34 fl oz

9.1

8.7

8.7

10

NOVEHA Pet Gel Eye Drops with 0.3% Viscoadaptive Hyaluronan | Eye Solution for Severe Dry Eyes - Long Lasting Hydration, Reduces Nuisance, Swelling & Dryness - Eye Lube for Dogs and Cats (2x10mL)

9.9

8.0

8.0

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