9 Best enzyme carpet cleaners of 2025

Explore top picks

Best Choice

1

AmazonCommercial
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
Main highlights

Powerful Enzymatic Cleaning
Breaks down complex organic proteins, pet stains, and odors on various surfaces.

Ideal for Pet Owners
Perfect for homes with pets, tackling messes on carpets, furniture, and more.

Highly Praised Odor Elimination
Customers love its ability to eliminate odors, not just mask them.
9.9

Exceptional

Our Rating

9.3
Simple to use

9.1
worth the money

8.9
Odor elimination
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Value for Money

2

P & S PROFESSIONAL DETAIL PRODUCTS
P & S PROFESSIONAL DETAIL PRODUCTS - Terminator Enzyme Spot & Stain Remover - Perfect for Deoderizing, Removing Embedded Soils, Grease, Dirt and Protein Based Stains; Fresh Scent (1 Gallon)
Main highlights

Key Features
Powerful enzyme cleaner attacks grease, oil, dirt, and food stains. Deodorizes with a fresh scent. Part of the Renny Doyle Double Black Collection.

Ideal Use Cases
Perfect for pre-treating spots and stains on carpets and upholstery before shampooing. Suitable for both home and professional detailing applications.

Customer Praise
Users highly commend its effectiveness on tough stains, appreciating the fresh scent and the product`s ability to clean and deodorize in a single step.
9.8

Exceptional

Our Rating

9.7
Simple to use

9.3
Simple to take off

9.3
Aroma
3

Rug Doctor
Rug Doctor Pet Carpet Cleaner, 96 oz., Pro-Enzymatic Formula with 3X Action - Cleans, Deodorizes, & Deters Remarking, Concentrated Solution, Professional Grade for Pet Stains & Odors
Main highlights

3X Action Formula Cleans and Deodorizes
Rug Doctor Pet Carpet Cleaner uses a 3X action formula to effectively clean, deodorize, and deter pets from remarking.

Ideal for Pet and Household Stains
Perfect for homes with pets, tackling stains like urine, feces, vomit, and dirt with ease.

Praised for Fresh Scent and Effectiveness
Customers love its fresh scent and effective stain and odor removal without overpowering perfumes.
9.7

Exceptional

Our Rating

9.9
Simple to use

9.3
Aroma

9.1
worth the money
4

Bioda
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
Main highlights

Powerful Cleaning and Odor Control
This probiotic cleaner offers powerful cleaning and odor elimination for various surfaces, leaving a fresh lemon and sage scent.

Ideal for Pet and Household Use
Perfect for managing pet stains, odors, and maintaining household cleanliness, especially in bathrooms and kitchens.

Highly Effective Odor Elimination
Customers praise its ability to permanently eliminate tough odors, especially from pet-related incidents and organic waste.
9.6

Exceptional

Our Rating
5

Simple Solution
Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz
Main highlights

Powerful Enzymatic Formula
Three times stronger than regular formulas, effectively removes tough pet stains and odors.

Versatile Home Use
Ideal for cleaning dog and cat urine, feces, vomit on carpets, upholstery, and more.

Highly Praised Sprayer
Customers love the improved sprayer for its fine mist and no leakage.
9.5

Excellent

Our Rating

9.7
Odor elimination

9.3
Comfort

9.1
deep clean
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6

Rocco & Roxie Supply Co.
Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover for Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray For Home, Puppy Potty Training
Main highlights

Eliminates Major Stains, Odors, and Residue
The product effectively removes tough stains and odors from various surfaces, leaving a subtle Meyer lemon scent that quickly dissipates.

Ideal for Pet Owners with Multiple Animals
Best used on carpets, floors, furniture, clothing, pet bedding, litter boxes, travel crates, and cars where pet accidents frequently occur.

Highly Effective on Tough Stains and Odors
Customers consistently praise the product's ability to completely eliminate pet urine odors and prevent re-marking, even on stubborn, old stains.
9.4

Excellent

Our Rating

9.9
worth the money

9.9
Stain resistance

9.5
Simple to use
7

OdoBan
OdoBan 3-n-1 Carpet Cleaner, 128 Fl Oz
Main highlights

3-in-1 Functionality
Combines traffic lane pretreatment, extraction cleaner, and spot remover efficiently.

Ideal for Pet Owners
Perfect for removing pet stains and odors from carpets.

Customer Favorite Freshness
Leaves carpets smelling fresh without a lingering odor.
9.3

Excellent

Our Rating
8

Calyptus
Calyptus Pet Stain and Odor Remover | Orange and Enzyme Cleaner Duo Solution for Pets | 128oz (64oz x 2 Bottles) | Carpet Cleaner and Odor Eliminator for Cat Urine, Dog Pee, and Poop | Pro Strength
Main highlights

Revolutionary Probiotic Technology
Advanced formula targets and eliminates odor-causing proteins for superior cleaning.

Ideal for Pet Owners
Perfect for removing pet stains and odors from carpets and furniture.

Highly Praised Odor Elimination
Customers love its ability to completely remove odors from surfaces.
9.2

Excellent

Our Rating

9.9
Odor elimination

9.7
Stain resistance

9.3
Aroma
9

FOLEX
FOLEX Instant Carpet Spot Remover, 32oz
Main highlights

Powerful Stain Removal
Effectively removes a wide range of stains including pet accidents, wine, and coffee.

Versatile Cleaning Solution
Ideal for carpets, upholstery, and clothing, making it perfect for households with kids or pets.

Highly Praised Performance
Customers rave about its ability to remove stubborn, old stains easily.
9.1

Excellent

Our Rating

9.5
Simple to use

9.1
worth the money

9.1
Aroma

9 Best enzyme carpet cleaners of 2025

1

AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack

9.3

9.1

8.9

2

P & S PROFESSIONAL DETAIL PRODUCTS - Terminator Enzyme Spot & Stain Remover - Perfect for Deoderizing, Removing Embedded Soils, Grease, Dirt and Protein Based Stains; Fresh Scent (1 Gallon)

9.7

9.3

9.3

3

Rug Doctor Pet Carpet Cleaner, 96 oz., Pro-Enzymatic Formula with 3X Action - Cleans, Deodorizes, & Deters Remarking, Concentrated Solution, Professional Grade for Pet Stains & Odors

9.9

9.3

9.1

4

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

5

Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz

9.7

9.3

9.1

6

Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover for Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray For Home, Puppy Potty Training

9.9

9.9

9.5

7

OdoBan 3-n-1 Carpet Cleaner, 128 Fl Oz

8

Calyptus Pet Stain and Odor Remover | Orange and Enzyme Cleaner Duo Solution for Pets | 128oz (64oz x 2 Bottles) | Carpet Cleaner and Odor Eliminator for Cat Urine, Dog Pee, and Poop | Pro Strength

9.9

9.7

9.3

9

FOLEX Instant Carpet Spot Remover, 32oz

9.5

9.1

9.1

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