10 Best anti itch treatments of 2025

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Best Choice

1

Aquaphor
Aquaphor Itch Relief Ointment, Maximum Strength 1% Hydrocortisone, Relieves Itch from Skin Irritation, Insect Bites, Psoriasis, Skin Rashes, Eczema, & Poison Ivy, 2 oz
Main highlights

Long Lasting Itch Relief
Aquaphor Itch Relief ointment provides soothing relief for up to 12 hours.

Versatile Use Cases
Ideal for insect bites, poison ivy, dry skin, and psoriasis.

Praised Texture
Customers appreciate its long-lasting effect, despite its Vaseline-like texture.
Key specs
- form:Tube
- size:2 ounces
- cream type:Itch Relief Ointment
- active ingredient:1% hydrocortisone
- application method:Ointment
9.8

Exceptional

Our Rating

8.7
pain management

8.2
quality of ingredients

8.0
Moisturizing
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Value for Money

2

Calagel
Tecnu Calagel Anti-Itch Gel, Maximum Strength Itch Relief for Rashes, Bug Bites, Stings and Minor Burn Relief, 6 oz
Main highlights

Quick and Effective Relief
Provides fast relief for insect bites, sunburns, and minor rashes, using maximum strength diphenhydramine HCl 2%.

Versatile Use Cases
Ideal for soothing bug bites, stings, sunburn, and minor burns, making it a versatile addition to any first aid kit.

Highly Praised Itch Relief
Customers consistently praise its ability to significantly reduce itching from insect bites and irritants.
9.7

Exceptional

Our Rating

9.3
Aroma

9.1
worth the money
3

Benadryl
Benadryl Extra Strength Anti Itch Relief Gel, 2% Diphenhydramine HCl, Relief from Insect Bites, Sunburn & More, Great for Camping Essentials, 3.5 fl oz

25% Off
Main highlights

Fast-Acting Cooling Relief
Benadryl Extra Strength Gel provides quick relief from itching and pain caused by insect bites, sunburn, and minor skin irritations.

Outdoor Activity Essential
Ideal for camping, hiking, and outdoor events, offering relief for ages 2 and up.

Instant Itch Control
Customers praise its immediate itch relief and cooling sensation, making it a must-have for skin irritations.
Key specs
- Item Form:Gel
- Recommended Use:Insect bites, sunburn
- Dimensions:1.47 x 2.43 x 6.35 inches
- Special Feature:Anti-itch relief
- Reusability:N/A
9.4

Excellent

Our Rating

8.7
Simple to use

8.4
worth the money

8.4
For traveling
4

Cortizone 10
Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.
Main highlights

Maximum Strength Relief
Contains 1% hydrocortisone for fast, effective itch relief.

Ideal for Itch and Irritation
Perfect for eczema, psoriasis, insect bites, and rashes.

Praised for Quick Absorption
Non-greasy formula absorbs quickly, leaving no residue.
Key specs
- form:Cream
- size:2 oz.
- cream type:Anti-Itch Cream
- active ingredient:1% hydrocortisone
- application method:Topical
9.3

Excellent

Our Rating
5

Campho-Phenique
Campho Phenique Maximum Strength Antiseptic Liquid, Pain Relief and Anti-Itch Treatment, Provides Instant Relief From Bug Bites, Minor Cuts and Skin Irritations, 0.75 Oz

29% Off
Main highlights

Instant Pain and Itch Relief
Campho-Phenique provides immediate relief from pain and itching for insect bites and minor skin irritations.

Ideal for Insect Bites and Burns
Perfect for treating insect bites, minor skin irritations, and burns in adults and children over 2 years.

Generational Trust and Effectiveness
Praised for its long-lasting effectiveness and nostalgic scent, trusted by families for decades.
Key specs
- Usage:Insect bites, minor burns
- Formulation:Anesthetic and antiseptic
- Country of Origin:USA
- Active Ingredients:N/A
- Skin Type:N/A
9.1

Excellent

Our Rating

9.9
pain management

9.7
worth the money

8.0
Aroma
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6

Globe
Globe (4 Pack) Hydrocortisone Maximum Strength Anti-Itch Cream 1% w/Aloe, Intensive Formula for Redness, Rash, Bug & Mosquito Bites, Eczema, Hemorrhoids, Sensitive Skin, Instant Itch Relief,1 oz Tube

49% Off
Main highlights

Maximum Strength Relief with Aloe
Combines hydrocortisone 1% with aloe vera for soothing, moisturizing relief.

Versatile Home and Travel Use
Effective for skin irritations, rashes, insect bites, and more.

Great Value and Quantity
Affordable multi-pack praised for its convenience and cost-effectiveness.
9.0

Excellent

Our Rating
7

Nizoral
Nizoral Scalp Itch Relief Liquid—Relieves Scalp Itch and Soothes, Calms and Hydrates with Maximum Strength Anti-Itch Medicine (Hydrocortisone 1%), 2 Fl Oz
Main highlights

Maximum Strength Itch Relief
Contains Hydrocortisone 1% with aloe, menthol, vitamin E, and hyaluronic acid to soothe and hydrate the scalp.

Ideal for Dandruff and Dry Scalp
Perfect for managing seborrheic dermatitis, psoriasis, eczema, and general scalp itchiness.

Praised for Shine and Frizz Control
Users love its ability to add shine and manage split ends and frizz.
Key specs
- form:Solution
- size:2 ounces
- cream type:Medicated
- active ingredient:Hydrocortisone 1
- application method:Directly to scalp
8.9

Very Good

Our Rating
8

Cortizone 10
Cortizone 10 Maximum Strength Intensive Moisture Anti-Itch Cream, 1% Hydrocortisone, 2 oz.
Main highlights

Maximum Strength Itch Relief
Cortizone-10 provides fast relief from itch with maximum-strength hydrocortisone and nourishing moisturizers.

Ideal for Minor Skin Irritations
Perfect for relieving itch from dry, chafed, and chapped skin.

Instant Relief and No Grease
Highly praised for its quick action and non-greasy feel.
Key specs
- form:Cream
- size:2-oz. tube
- cream type:Anti-Itch Cream
- active ingredient:1 hydrocortisone
- application method:Topical
8.8

Very Good

Our Rating
9

Cutter
Cutter BiteMD Insect Bite Relief Stick, Analgesic And Antiseptic 0.5 Fl Oz (Pack of 1)
Main highlights

Fast Relief and 3-in-1 Formula
Provides immediate pain relief, itch reduction, and infection prevention.

Perfect for Outdoor Adventures
Ideal for hiking, traveling, and family outings with insect exposure.

Compact Design and Ease of Use
Highly praised for its convenience and effective, mess-free application.
Key specs
- Item Form:Stick
- Recommended Use:Insect bites
- Dimensions:4 x 1 x 8 inches
- Special Feature:3-in-1 formula
- Reusability:N/A
8.7

Very Good

Our Rating

9.9
pain management

9.7
movability

8.9
For traveling
10

Benadryl
Benadryl Extra Strength Itch Relief Stick, Diphenhydramine HCL Topical Analgesic & Zinc Acetate to Relieve Skin Itching & Pain Associated with Insect Bites, Sunburn & More, 0.47 fl. oz
Main highlights

Fast Itch and Pain Relief
.47-fluid ounce stick provides quick relief from itching and pain.

Compact and Portable Design
Ideal for on-the-go relief from insect bites and minor skin irritations.

Instant Relief Praised by Users
Customers appreciate its effectiveness and portability for emergency use.
Key specs
- Item Form:Stick
- Recommended Use:Insect bites, sunburn
- Dimensions:6.04 x 0.98 x 0.84 inches
- Special Feature:Fast relief from itching
- Reusability:N/A
8.6

Very Good

Our Rating

9.9
movability

9.9
Simple to use

9.7
pain management

10 Best anti itch treatments of 2025

1

Aquaphor Itch Relief Ointment, Maximum Strength 1% Hydrocortisone, Relieves Itch from Skin Irritation, Insect Bites, Psoriasis, Skin Rashes, Eczema, & Poison Ivy, 2 oz

8.7

8.2

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Tecnu Calagel Anti-Itch Gel, Maximum Strength Itch Relief for Rashes, Bug Bites, Stings and Minor Burn Relief, 6 oz

9.3

9.1

3

Benadryl Extra Strength Anti Itch Relief Gel, 2% Diphenhydramine HCl, Relief from Insect Bites, Sunburn & More, Great for Camping Essentials, 3.5 fl oz

8.7

8.4

8.4

4

Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.

5

Campho Phenique Maximum Strength Antiseptic Liquid, Pain Relief and Anti-Itch Treatment, Provides Instant Relief From Bug Bites, Minor Cuts and Skin Irritations, 0.75 Oz

9.9

9.7

8.0

6

Globe (4 Pack) Hydrocortisone Maximum Strength Anti-Itch Cream 1% w/Aloe, Intensive Formula for Redness, Rash, Bug & Mosquito Bites, Eczema, Hemorrhoids, Sensitive Skin, Instant Itch Relief,1 oz Tube

7

Nizoral Scalp Itch Relief Liquid—Relieves Scalp Itch and Soothes, Calms and Hydrates with Maximum Strength Anti-Itch Medicine (Hydrocortisone 1%), 2 Fl Oz

8

Cortizone 10 Maximum Strength Intensive Moisture Anti-Itch Cream, 1% Hydrocortisone, 2 oz.

9

Cutter BiteMD Insect Bite Relief Stick, Analgesic And Antiseptic 0.5 Fl Oz (Pack of 1)

9.9

9.7

8.9

10

Benadryl Extra Strength Itch Relief Stick, Diphenhydramine HCL Topical Analgesic & Zinc Acetate to Relieve Skin Itching & Pain Associated with Insect Bites, Sunburn & More, 0.47 fl. oz

9.9

9.9

9.7

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